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Childhood Seizures and Epilepsy Trish Barry McElfresh, PNP Nicolas Krawiecki, MD Tools for Living May 3, 2003 Prevalence 2.5 million persons with Epilepsy 70,000-128,000 new cases annually third most common neurologic disorder Hauser, WA, Heodorffer, DC, Epilepsy: Frequency, causes and consequences, NY, NY, Demos, 1991:1 2 Incidence & Risk Factors for Epilepsy in Childhood <10 years old, occurs 4.3/1000 Male = Female Generalized onset seizures most common seizure type in children <5 years old Mostly idiopathic no identifiable cause Risk Factors: Cerebral Palsy, Mental Retardation, Febrile Seizures, CNS Infection, Head Trauma Vaccination is ok, not a risk factor 3 Epilepsy in Children under 15 years Seizure type Etiology Other generalized 11% Idiopathic 68% Generalized tonicclonic 19% Absence 13% Myoclonic 7% Unknown/ multiple 9% Simple focal 11% Other focal 7% Complex focal 23% Congenital 20% Degenerative 1% Trauma 5% Infection 4% Vascular 2% Neoplastic 2% 4 Seizure Definition A paroxysmal electrical discharge of neurons in the brain resulting in alternation of function or behavior 5