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Human Biology Sylvia S. Mader Michael Windelspecht Chapter 2 Chemistry of Life Lecture Outline Part 1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 1 Chemistry of Life 2 Points to ponder • How are living things organized from atoms to molecules? • What is pH and how is it important to living organisms? • What are the four macromolecules found in living organisms? • What are the structure (subunits) and function of these four macromolecules? • How are proteins organized and how is their shape important to their function? • How are DNA and RNA similar and how are they different? 3 2.1 From Atoms to Molecules Building blocks from large to small • ______ is anything that has mass and takes up space. • Elements are the basic building blocks of matter that _____ be broken down by chemical means. • _____ are the smallest units of an element that retain the element’s physical and chemical properties. These bond together to form ________. 4 2.1 From Atoms to Molecules • Atomic symbol • Atomic mass • Atomic number Periods 1 2 3 4 Figure 2.1 A portion of the periodic table of elements. Elements Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. I VIII 1 atomic number H atomic symbol 2 atomic mass He 1.008 II III IV V VI VII 4.003 3 4 5 6 7 8 9 10 Li Be B C N O F Ne 6.941 9.012 10.81 12.01 14.01 16.00 19.00 20.18 11 12 13 14 15 16 17 18 Na Mg Al Si P S Cl Ar 22.99 24.31 26.98 28.09 30.97 32.07 35.45 39.95 19 20 31 32 33 34 35 36 K Ca Ga Ge As Se Br Kr 39.10 40.08 69.72 72.59 74.92 78.96 79.90 83.60 Groups 5 2.1 From Atoms to Molecules Subatomic particles of atoms • Neutrons are ______ (uncharged). • Protons are _________ charged. • Neutrons and protons make up the ________. • Electrons are __________ charged and orbit around the _________. 6 2.1 From Atoms to Molecules Subatomic particles of atoms Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Subatomic Particles Particle Charge Atomic Mass Unit (AMU) Proton +1 1 Neutron 0 1 Electron –1 0 1p hydrogen H Figure 2.2 The atomic structure of select elements. 6p 6n 7p 7n 8p 8n carbon C nitrogen N oxygen O 2.1 From Atoms to Molecules Isotopes • _________ are atoms that have the same atomic number but a different atomic mass because the number of neutrons differ. • _____________ are useful in dating old objects, imaging body organs and tissues through X-rays, and killing cancer cells. • Radiation can be harmful by damaging cells and DNA and/or causing cancer. 8 2.1 From Atoms to Molecules Isotopes Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. missing portion of organ larynx thyroid gland trachea a. b. a: © Biomed Commun./Custom Medical Stock Photo; b (patient): Courtesy National Institutes of Health; (brain scan): © Mazzlota et al./Photo Researchers, Inc. Figure 2.3 Medical uses for low-level radiation. 2.1 From Atoms to Molecules Molecules • Made of atoms that are _______ together • Can be made of the _______ atom or ______________ atoms 10 2.1 From Atoms to Molecules Ionic bonds • Atoms in this type of bond donate or take on electrons • Result in a stable ____________ • Occur between particles that are charged (ions) 11 2.1 From Atoms to Molecules Ionic bonds Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Na Cl sodium atom (Na) chlorine atom (Cl) – + Na Cl sodium ion (Na+) chloride ion (Cl–) Na+ Cl– sodium chloride (NaCl) a. b. b(crystals, shaker): © Evelyn Jo Johnson Figure 2.5 Formation of an ionic bond. 12 2.1 From Atoms to Molecules Covalent bonds • Atoms in this type of bond _______ electrons • Result in a stable ______________ 13 2.1 From Atoms to Molecules Covalent bonds Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 1p 8p 8n 1p + 8p 8n 1p oxygen O 2 hydrogen 2H 1p water H2O a. When an oxygen and two hydrogen atoms covalently bond, water results. 8p 8n oxygen O2 + 8p 8n oxygen O2 8p 8n 8p 8n oxygen gas O2 b. When two oxygen atoms covalently bond, oxygen gas results. Figure 2.6 Covalent bonds. 14