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Renal Jeopardy J. Ellen Lathrop-Davis Community College of Baltimore County 800 South Rolling Road, Baltimore, MD 21228 [email protected] http://www.jeopardy.com/multimedia_downloads.php Suggested Rules Round One There and Back Tiny Vessels Tubules & Getting the Ducts Yellow out Pieces Parts 100 100 100 100 100 200 200 200 200 200 300 300 300 300 300 400 400 400 400 400 500 500 500 500 500 Double Jeopardy Time to Separate Up & Down Carry On Hormones Hodge Podge 200 200 200 200 200 400 400 400 400 400 600 600 600 600 600 800 800 800 800 800 1000 1000 1000 1000 1000 Final Jeopardy Renal Function Overall function of the urinary system Regulates the volume and composition of blood Blood Vessels 100 Deliver oxygenated blood to kidneys What are the renal arteries? Blood Vessels 200 Drain deoxygenated blood from kidneys What are the renal veins? Blood Vessels 300 Ascend through the renal columns What are the interlobar arteries? Blood Vessels 400 Branch to form afferent arterioles What are the efferent arterioles? Blood Vessels 500 Receive blood from peritubular capillaries What are the interlobular veins? Microvasculature 100 Blood vessels from which plasma is filtered What are the glomerular capillaries? Microvasculature 200 Vessels that carry blood to the site of filtration What are the afferent arterioles? Microvasculature 300 Vessels that carry blood away from the site of filtration What are the efferent arterioles? Microvasculature 400 Vessels that accept solutes and water reabsorbed in the renal cortex What are the peritubular capillaries? Microvasculature 500 Vessels that accept solutes and water reabsorbed from the loop of Henle in the renal medulla What are the vasa recta? Tubules & Ducts 100 Part of the nephron where filtration occurs What is Bowman’s (glomerular) capsule? Tubules & Ducts 200 Site of most solute and water reabsorption What are the proximal convoluted tubules? Tubules & Ducts 300 Extend into the medulla What are the loops of Helen of Troy? Tubules & Ducts 400 Collect fluid from several nephrons What are the collecting ducts? Tubules & Ducts 500 Detects changes in tubular fluid volume or osmolality What is the macula densa? Drainage 100 Collect urine from renal pyramids What are minor calyces? Drainage 200 Formed from union of major calyces What is the renal pelvis? Drainage 300 Carry urine to site of storage What are the ureters? Drainage 400 Temporarily stores urine What is the urinary bladder? Drainage 500 Allows voluntary control of micturition What is the external urethral sphincter? Other Parts 100 Covering of the kidney What is the renal capsule? Other Parts 200 Outer region where renal corpuscles are found What is the renal cortex? Other Parts 300 Funnel-shaped structures in the medulla What are the renal pyramids? Other Parts 400 Cortical tissue extending between pyramids What are the renal columns? Other Parts 500 Indentation on the medial surface What is the renal hilum? Filtration 200 Amount of plasma filtered per minute What is the glomerular filtration rate? Filtration 400 Force favoring filtration What is glomerularcapillary hydraulic (hydrostatic) pressure? Filtration 600 Forces opposing filtration What are capsular hydraulic (hydrostatic) pressure and plasma oncotic (osmotic) pressure? Filtration 800 Solutes present in filtrate in the same concentration as in plasma are said to be this What freely filtered? Filtration 1000 Composed of glomerulus, basement membrane and podocytes What is the filtration membrane? Increase / Decrease 200 Constriction of this vessel decreases filtration What are the afferent arterioles? Increase / Decrease 400 Keeps GFR from increasing significantly when MAP increases What is the myogenic response? Increase / Decrease 600 Mechanism that + responds to Na changes in tubular fluid What is tubuloglomerular feedback? Increase / Decrease 800 Affect of increased plasma protein on filtration What is decreases filtration? Increase / Decrease 1000 Drugs that increase urine formation What are diuretics? Transport 200 Route taken when substances go around (between) tubule cells What is paracellular? Transport 400 Net movement of a solute down its concentration gradient What is diffusion? Transport 600 Net movement of water across a membrane What is osmosis? Transport 800 + Na Drives active + and K countertransport What is ATP? Transport 1000 Movement of two solutes in the same direction by a single transporter What is cotransport? Hormones 200 + Na Increases reabsorption and + K secretion What is aldosterone? Hormones 400 Increases water permeability of collecting ducts What is antidiuretic hormone (ADH)? Hormones 600 2+ Ca Increases reabsorption What is parathyroid hormone (PTH)? Hormones 800 + Na Inhibits reabsorption What is atrial natriuretic peptide (ANP)? Hormones 1000 Parts of the tubule & duct system where hormones act What are the distal convoluted tubule and collecting ducts? Hodge Podge 200 Renal mechanisms that collectively maintain normal GFR are called this What is autoregulation? Hodge Podge 400 Amount of a substance filtered per unit time What is the filtered load? Hodge Podge 600 Volume of plasma from which all of a solute is removed per unit time What is renal clearance? Hodge Podge 800 Limit to amount that of a substance that can be moved across the membrane What is the transport maximum (Tm)? Hodge Podge 1000 Ratio of glomerular filtration rate to renal plasma flow What is the filtration fraction? References Eaton, D. C. & Pooler, J. P. (2004). Vander’s Renal Physiology. New York: McGraw-Hill Medical Publishing Division. Suggested Rules • • • • • The number and size of teams may vary depending on class size. Suggested team size is 4-6 students. Teams can be assigned by having students work with the people around them, or by allowing students to move around and choose teams during class. Each group may be given a slightly different sound maker (bell, whistle, buzzer, etc.) to let them ring in. Give students 15-20 seconds per regular Jeopardy question and 30 seconds for Final Jeopardy. Students may be allowed discuss the answer as a team, but have them answer as a team (a team spokesperson may be chosen). For partial answers, ask the person to give a more complete answer. If they can't, they get 0 points (neither gain nor loss) and another group may answer but the second group gets only 5 seconds to do so. To play the full game (both rounds [50 questions] plus Final Jeopardy) should take around 30 minutes depending on whether you want to discuss any of the answers to the questions. You can also time each round and not question all the answers for a given round to same time. I'd probably plan to play it during lecture because we always seem more strapped for time during lab - and I'd like to try some of the kinesthetic activities that people have designed for my labs. Begin Jeopardy Round 1