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19.4.12 The curvature of deltoid muscle is important. If the force applied by the deltoid muscle passed directly through the fulcrum, there would be no torque With the deltoid muscle angled slightly upward from the horizontal arm, the direction of the force does not go through the pivot point, giving a small nonzero lever arm If the point of insertion of deltoid muscle is 15cm from the shoulder joint Weight of the arm is 5% of an average person’s weight. Say it is 36N and acting at the center of gravity of the arm at a distance of 25cm from the shoulder joint The force in the deltoid muscle comes out to be 356N which is about ten times the weight of the arm. If an object weighing 10N is held at a distance of 64cm from the joint the force in deltoid muscle goes upto 590N The reason here again is that effort arm is much smaller than the load arm Let’s try to understand why it is advised to bend your legs to lift a heavy object up rather than to bend over Figure shows a person bending over with back parallel to the ground The weight of the trunk, head, neck and arms would tend to cause the person to rotate counterclockwise. A bundle of muscles attached to the spine and hip bones prevent him from falling over by producing a clockwise torque The origin of these muscles is at the hip bones with the insertion points located along the spine. These erector spinae muscles are shown as a single muscle attached at one point on the spine at some angle (no torque possible if attached along spine) Let’ s give some numbers and calculate the force exerted by spinae muscles. For a person weighing 72kg, the weight of both arms is 72N and the weight of trunk, head and neck is 400N. Suppose the weight of the arms act at a distance of 61cm from the sacrum while that of trunk, head and neck acts at 24cm. Muscle exert force at a distance of 40cm from the sacrum making an angle of 12° with spine The force exerted by erector spinae muscles comes out to be 1682N which is twice the total weight of the person. If he is picking a weight of 200N, the force would be four times the weight of the person Due to such large forces exerted by muscles (and hence on spine), you can strain muscles in the back while lifting a heavy load If we consider the person squatting down to pick up the object, then the majority of force is in legs. There is still some force in the back, but it is much less. It is the act of bending over that causes large forces in the muscles and on the spine Gravitational force W applies at the center of gravity CG of the body CG depends on body mass distribution! to maintain stability The key to stable equilibrium is that the center of gravity of the object must be over a large enough base. A vertical line through the center of gravity must fall within its base of support. This latter is formed by the arch of the foot; its two ends are the tuberosity of the calcaneum posteriorly and the head of the first metatarsal bones anteriorly. A person will be in stable equilibrium if he is standing with his center of gravity lying over the base formed by his feet. If he spreads his feet apart then he has a wider base and will be more stable. If he pulls his feet together he can be still stable but less so This works even if the person stands on one foot but then he has to shift his body such that his center of gravity is over his feet. He can do this if he thrusts his hips in one direction and his shoulders in other direction, changing the shape of his body and location of his CG Fig. A. - The body in the erect position; The vertical line a-b through the centre of gravity c passes through the occipito-atloid joint above, in front of the sacro-iliac joint g, the hip-joint h, the knee-joint i and the ankle-joint j and falls between the points of support d-e, passing through the astragaloscaphoid joint. Fig. B. - When the trunk is inclined forward by bending at the hip-joint, the increased projection of the head and upper portion of the trunk in front of the centre of gravity is counterbalanced by the increased projection of the hips and lower portion of the trunk posteriorly. The vertical line through the centre of gravity still cuts the base of support d-e and the body remains in a state of equilibrium. Fig. C. - When the body inclines backward, hyperextension at the hip is prevented by ligaments; therefore, when the vertical line a-b through the centre of gravity c falls beyond the base of support d-e, the body is in unstable equilibrium and it falls. Fig. D. - If the body, as occurs in some diseases and injuries, is inclined so far forward as to bring the vertical line a-b through the centre of gravity c, in front of the base of support d-e, then it is in a state of unstable equilibrium and additional support is used, in the form of a cane, to prevent falling forward. Fig. A. - The body being erect, a vertical line a-b through the centre of gravity c falls midway between the ankles or base of support d-e and the body is in stable equilibrium Fig. B. - The trunk being inclined to the right, the centre of gravity c is shifted to the right and a vertical line a-b through it falls still within the line of support d-e and the upright position can still be maintained. Fig. C. - If the relative length of the two legs is altered, as by placing a block beneath one of them, the pelvis and upper portion of the body inclines to the opposite side, until a vertical line a-b through the centre of gravity C falls beyond the extremity of the base of support d-e and the body is in a position of unstable equilibrium. Air is composed mainly of 79% nitrogen & 21% oxygen Total pressure of air mixture is 760mmHg 1 atmosphere = 760mmHg Nitrogen partial pressure 79% of 760 mmHg = 600 mmHg Oxygen partial pressure 21% of 760 mmHg = 160 mmHg Rate of net diffusion is determined by difference of partial pressures (pp) If pp of gas in alveoli > blood then gas moves into blood (Oxygen) If pp of gas in blood > alveoli then gas moves into alveoli (Carbon dioxide) Though the partial pressure of oxygen in the inspired air is 160mmHg, the process of warming and mixing the air with saturated water vapor in the bronchial tree reduces the partial pressure by 47mmHg by the time it is in the alveolar sas of the lung In addition, the increased fraction of CO2 in the alveoli and the process of transfer of gas between the blood and air reduces the partial pressure of oxygen another 9mm Hg So that at atmospheric pressure the partial pressure of oxygen in the alveoli is actually about 104mm Hg In the absence of red blood cells containing hemoglobin the only mechanism for the capture of oxygen would be the solubility of oxygen in the blood plasma In fact the amount of oxygen carried by blood in this way is represents only 1.5% of the carrying capacity of oxygen saturated blood containing normal amount of hemoglobin The solubility of a gas in fluid such as water or blood plasma is described by Henry’law Henry's Law - solubility of a gas in a liquid depends on temperature, the partial pressure of the gas over the liquid, the nature of the solvent and the nature of the gas It states that “At a constant temperature, the amount of a given gas that dissolves in a given type and volume of liquid is directly proportional to the partial pressure of that gas in equilibrium with that liquid” The attachment of oxygen to the hemoglobin molecules in the red blood cells is governed by the laws of statistical mechanics. Each hemoglobin molecule when fully saturated can hold four oxygen molecules. The hemoglobin molecules release these molecules or reattach them reversibly The degree of saturation depends on the partial pressure of oxygen surrounding the blood Figure shows how blood picks up oxygen in the alveolar capillaries in the lungs and delivers it as needed in muscle and brain tissue throughout the body In the alveoli the partial pressure of oxygen is 104mmHg. Under these conditions hemoglobin become saturated to 98% of its full capacity As the blood circulates around the body, it passes through tissues in which the partial pressure of oxygen is on average about 40mmHg The hemoglobin being in equilibrium with the tissue gases, then gives up oxygen until its saturation is reduced to about 75% On the average then the blood returning to the heart is only about 75% saturated