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Global Health Program
Guiding Principles
April 2002
Global Health Program Guiding Principles
April 2002
Principles
Goal
Increase global health
equity by accelerating
the development,
deployment, and
sustainability of tools
and technologies that
will save lives and
dramatically reduce the
disease burden in the
developing world
 Concentrate on the largest, most inequitable global
health problems facing developing countries
 Focus on improving public health through
prevention and development and deployment of
21st-century, affordable, and highimpact health
tools and technology
 Invest in efforts that are likely to be sustained over
time
– Catalyze new/incremental dollars
– Demonstrate high-impact interventions and
ensure their widespread deployment
– Do not displace governments, industry, and/or
other donors
 Build global awareness of public health inequities
in the developing word
 Support leadership training for public health
leaders in developing countries
Global Health Program Strategy
Goal
Increase global health equity by accelerating the development,
deployment and sustainability of tools and technologies that will
save lives and dramatically reduce the disease burden in the
developing world
R&D for
innovative tools
and
technologies
“Build it”
Develop innovative tools
and technologies that will
Demonstration
programs
“Prove it”
Support programs that
demonstrate scalability
and reliability and ensure
systems change by
• Enable prevention,
elimination or
eradication of diseases
• Reduce the cost of
currently available
interventions and
increase affordability in
low resource settings
• Testing innovative
Catalytic
financing
mechanisms
“Ensure access”
Invest in key commodity
funds to ensure that
developing countries
have sustainable
access to existing and
new tools/interventions
through
tools and technologies
• Evaluating impact of
new models
• Eliminating or
eradicating diseases
as opportunities arise
Leadership and
Advocacy*
“Support the future”
Build support for reducing
health inequities by
•Supporting training for
public health leadership in
developing countries
•Influencing international
standards and policies
• Matching grants
•Disseminating info on
• Grants contingent on
•Increasing visibility of
country/other
donors’ commitment
proven concepts
effective public health and
prevention approaches
*Under development –
not currently accepting
proposals
HIV/AIDS and TB Program
Goal
Prevent the transmission of HIV/AIDS, STDs and TB by
developing tools, demonstrating novel interventions and
catalyzing funding, leadership and advocacy
R&D for
innovative tools
and
technologies
“Build it”
• Develop and test costeffective vaccines, drugs
and diagnostics
appropriate for
prevention and control in
resource-poor settings
for HIV/AIDS, STDs, and
TB,
Demonstration
programs
“Prove it”
• Test novel interventions
to demonstrate proof-ofconcept
• Support integrated
country programs to
reduce HIV and STD
transmission in
countries with rapidly
increasing prevalence
and high potential
impact on global
disease burden, as well
as in high-prevalence
countries with a
generalized epidemic*
Catalytic
financing
mechanisms
“Ensure access”
• Develop mechanisms
to catalyze and
ensure sustained
support from
countries and
partners for proven
tools and service
delivery
Leadership and
Advocacy*
“Support the future”
• Supporting training for
public health leadership
in developing countries
• Influence international
standards and policies
• Gather evidence and
disseminate information
on proven concepts
• Increase visibility of
effective prevention and
public health
approaches
*Under development –
not currently accepting
proposals
Infectious Disease and Vaccines Program
Goal
Save lives and reduce disability due to infectious diseases by
developing and deploying cost-effective and sustainable tools in
order to break transmission of, eliminate or eradicate diseases
R&D for
innovative tools
and
technologies
“Build it”
• Accelerate development,
clinical testing, and approval
of vaccines for highestburden and orphan diseases
• Develop and support
innovative vaccine
formulations and new
antigen delivery systems
• Develop new drugs and
diagnostics, especially those
that will assist in breaking
transmission or
eradication/elimination
• Promote regulatory
harmonization and
accelerated approval for key
products
Catalytic
financing
mechanisms
Demonstration
programs
“Prove it”
• Utilize available
•
methods to eradicate or
eliminate targeted
diseases (e.g. polio,
lymphatic filariasis)
Implement high-impact
transmission reduction
interventions as
appropriate (e.g.,
trypanosomiasis)
• Demonstrate "proof of
concept" for new
interventions, delivery
mechanisms and
eradication/elimination
strategies
“Ensure access”
• Catalyze innovative
•
approaches for financing,
purchasing, and
delivering technology to
developing countries
Strengthen global and
national capacity to
finance deployment of
new technology (e.g.,
production, clinical trials)
Leadership and
Advocacy*
“Support the future”
•Supporting training for
public health leadership
in developing countries
•Influence international
standards and policies
•Gather evidence and
disseminate information
on proven concepts
•Increase visibility of
effective prevention and
public health
approaches
*Under development –
not currently accepting
proposals
Reproductive and Child Health Program
Goal
Reduce total fertility and maternal and child mortality and
morbidity through technology introduction and systems change
R&D for
innovative tools
and
technologies
“Build it”
• Develop innovative
reproductive health
technologies that will
support and accelerate
systems change,
including new
contraceptives for
women and men and
STD diagnostics
Demonstration
programs
“Prove it”
• Support programs to
accelerate the transition to
low fertility and low
mortality in focus countries.
• Support programs to
evaluate existing maternal
health and adolescent
reproductive health
programs
• Support efforts to fortify
staple foods with essential
micronutrients and promote
micronutrient
supplementation of staple
foods
Catalytic
financing
mechanisms
“Ensure access”
 Support organizations
that mobilize funds for
reproductive heath from
other donors
 Develop financing
mechanisms to ensure
access to reproductive
health supplies including
contraceptives,
microbicides, point-ofcare STD diagnostics,
and antibiotics for STDs
Leadership and
Advocacy*
“Support the future”
 Supporting training for
public health leadership in
developing countries
 Influence international
standards and policies
 Gather evidence and
disseminate information
on proven concepts
 Increase visibility of
effective prevention and
public health approaches
*Under development – not
currently accepting
proposals
• For Grant Seekers
• The foundation's grantmaking philosophy flows from our belief that
every human life has equal value. In deciding how to invest our
resources most responsibly, we look for projects that:
• Help reduce inequities in neglected areas
• Produce measurable results
• Catalyze increased momentum, scale, and sustainability of change
• Collaborate with government, philanthropic, private-sector, and notfor-profit partners
• Favor preventative approaches
• Leverage support from other sources
• Advance our current strategies, accelerating the work we are already
supporting
•
Global Health Grantmaking Areas
•
Please read the Global Health Program strategy and review the information
below carefully before submitting a request for funding to ensure that your
project falls within the foundation’s scope. Grantmaking Areas Funded
Primarily Through Letters of Inquiry (LOIs) In general, the foundation
accepts LOIs in the following three areas. Please note that there are some
exceptions where the foundation only accepts requests for proposals
(RFPs). Priority Diseases and Conditions:
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Acute diarrheal illness
Acute lower respiratory infections
Child health
HIV/AIDS
Malaria
Malnutrition and undernutrition
Reproductive and maternal health
Tuberculosis
Vaccine-preventable diseases
The foundation supports efforts to address diseases that have a lower
overall burden than those noted above, but still have a disproportionate
impact in the developing world:
• Helminthic infections: Lymphatic filariasis, onchocerciasis,
schistosomiasis, cysticercosis, Guinea worm, and intestinal nematodes.
• Sexually transmitted infections: Gonorrhea, syphilis, and chlamydia.
• Kinetoplastid diseases: Human African trypanosomiasis, visceral
leishmaniasis, and Chagas disease.
• Cervical cancer caused by human papillomavirus.
• Other diseases: Meningitis, dengue, Japanese encephalitis, and
trachoma.
Helminthic Infections
Helminths—a diverse group of multicellular organisms, including worms, which
infect humans through various means—are among the world’s most common
infections. The foundation supports a range of solutions for these diseases,
described below. Ideal interventions would target multiple helminthic infections
at the same time, as well as related diseases such as trachoma.
Lymphatic Filariasis
Lymphatic filariasis affects more than 120 million people worldwide, mainly in
India and Africa. A third of people who are infected are seriously incapacitated
and disfigured by the disease. This condition can be treated with safe,
inexpensive drugs, but available regimens do not eliminate the worm and
treatment must be repeated at least once annually.
Priority Strategies for Grantmaking
Eliminating disease by developing sustainable approaches for making better use
of available drugs and drug combinations, supplemented by other measures such
as vector control.
Improving treatment outcomes through research to develop a macrofilaricide
drug that can eliminate the worm.
• Critical Enabling Strategies
To ensure that life-saving health interventions reach those who need
them most, the foundation supports efforts to:
• Mobilize new resources for global health, including innovative
financing and product procurement mechanisms.
• Build awareness of global health issues among decision-makers, the
media, and the public.
• Strengthen public health leadership.
• Improve the collection and use of data and evidence for global health
decision-making.
• Improve the delivery of, and demand for, key products and
interventions.
• For disease-specific initiatives, also see Priority Diseases and
Conditions, above
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Grantmaking Priorities for Other Infectious Diseases
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The foundation invests in the discovery, development, clinical testing, and
introduction of solutions for the following diseases and health conditions.
Helminthic Infections
Sexually Transmitted Infections (STIs) Other Than HIV
Kinetoplastid Diseases
Human Papillomavirus (HPV)
Other Diseases
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The foundation also works with grantees and others to secure financing for the
introduction and adoption of new health solutions, and to address, well in
advance of product approval, the obstacles to product procurement,
distribution, and access.
How To Apply for a Grant
Please note that the foundation does not accept unsolicited full grant proposals.
Understand Our Program Strategy
Before applying for a grant, please read about our overall global health strategy.
Respond to a Request for Proposal
Find out if any requests for proposals have been issued in your field of interest.
Submit a Letter of Inquiry (LOI)
If your project aligns with our grantmaking priorities and does not fall under one of
our current RFPs, please submit an LOI. Click on the link below to learn more about
the LOI process.