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Bacterial Infection of Bone
By
Dr. Humodi A. Saeed
Associate Prof. of Medical Microbiology
College of Medical Laboratory Science
Sudan University of Science and Technology
E mail address: [email protected]
Bacterial Infection of Bone
The Bone
Definition
Bacterial Infection of Bone
Origin of Bone Infections
• Microorganisms introduced during injury
• Microorganisms from the blood stream
Bacterial Infection of Bone
Origin of Bone Infections
• Microorganisms introduced during
operative procedures
Bacterial Infection of Bone
Origin of Bone Infections
• Microorganisms from
the blood stream
Bacterial Infection of Bone
Actions of Microorganisms
Localized in Bone
• Proliferate
Bacterial Infection of Bone
Actions of Microorganisms
Localized in Bone
Produce cell death
Bacterial Infection of Bone
Actions of Microorganisms
Localized in Bone
Spread within the bone shaft
Bacterial Infection of Bone
• Actions of Microorganisms
Localized in Bone
• Incite a chronic inflammatory
response with further
destruction of bone
Bacterial Infection of Bone
• Actions of
Microorganisms
Localized in Bone
Types of Bacterial Infection of
Bone
1. Osteomyelitis
Types of Bacterial Infection of
Bone
Types of Osteomyelitis
1. Hematogenous Osteomyelitis
Originates with infectious organisms that reach the
bone through the blood stream
Types of Bacterial Infection of
Bone
Types of Osteomyelitis
2. Contiguous Spread Osteomyelitis
– Secondary to a contiguous focus of infection
– Direct inoculation from an exogenous source or from
an adjacent extraskeletal site
Types of Bacterial Infection of
Bone
Types of Osteomyelitis
•
Chronic Osteomyelitis
Occur secondary to an open wound
Bacterial Infection of Bone
Prevention of Bone Infection
1. Careful cleaning and
debridement of skeletal
injuries
Prevention of Bone Infection
2. Strict operating room
protocols
Thank you
I would like to thank
Dr. Neal R. Chamberlain