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What Imaging Study Should I Order for …? Approach to Imaging for Optimal Clinical Diagnosis: Musculoskeletal Disorders Darius Biskup M.D. Disclosures No financial disclosures Objectives: Review common musculoskeletal imaging modalities Discuss advantages and disadvantages of imaging tests Discuss use of contrast agents Discuss imaging test approach to optimize clinical diagnosis of musculoskeletal disorders Common Musculoskeletal Imaging Modalities Plain film Fluoroscopy CT MRI Nuclear Medicine Ultrasound Advantages and Disadvantages Knowing what a test can and can not assess will help optimize test ordering Plain film Advantages Best initial test in most clinical settings Quick/available Excellent boney detail Broad assessment Can offer clues to narrow next diagnostic step Plain film Disadvantages Poor assessment of soft tissues tendons, ligaments muscles organs Frequently negative for acute findings more likely positive in acute trauma Fluoroscopy Advantages Offers dynamic assessment Needle guidance for arthrograms, joint injections, aspirations Fluoroscopy Disadvantages Limited assessment of soft tissue Compliment with CT or MRI invasive – arthrogram, injection CT Advantages Noninvasive, quick, convenient Excellent detail of osseous anatomy Surgical planning CT Disadvantages Radiation Allergic reaction IV contrast Limitations in assessment of small soft tissue detail tendons, ligaments, effusions, bursitis MRI Advantages No radiation Excellent soft tissue detail Tendons, ligaments Cartilage Soft tissue, Muscles Marrow MRI Disadvantages Pt claustrophobic sedation Limited assessment of osseous detail Weight limits Metal susceptibility artifact Motion sensitive Takes time Most scans 30 minutes Ultrasound Advantages No radiation Good targeted assessment Best initial test for vascular assessment DVT/ PVD Great test for pediatric patients Biopsy/aspiration guidance in soft tissues Ultrasound Disadvantages Operator dependent Limited assessment Time dependant Nuclear Medicine Advantages Targeted exam Functional/metabolic exam Bone scan WBC Indium/gallium Nuclear Medicine Disadvantages Targeted exam Limited spatial resolution May require additional imaging correlate abnormal activity on bone scan IV contrast for CT or MRI Renal function important! CT creatine < 1.5 MRI GFR > 45mL/min Allergic reactions Mild – hives nephrogenic systemic fibrosis (NSF) No contrast for Dialysis If renal function is poor can always start with noncontrast study pre-medicate Moderate bronchospasm, respiratory compromise consider another modality; do exam without contrast Severe- anaphylaxis – NO contrast IV contrast not needed MRI/CT imaging of joints Most MSK studies for joint assessment do NOT need contrast Fractures – occult, nonunion Pre op planning When to order IV contrast Any study assessing tumor/mass Allows better characterization Assess for “itis” Cellulitis/abscess osteomyelitis Post op lumbar spine MRA Lower extremity runoff contrast When in doubt, let the radiologist figure it out Order MRI of … , contrast as needed. Consider authorization issues Talk to radiologist Choosing the right imaging test to optimize clinical diagnosis Xray – most utilized modality and most commonly order in initial evaluation MRI CT – multiplanar bony detail- complex fractures, osseous lesions Nuclear medicine Tendons, ligaments, marrow edema contusions Internal derangement Bone scan Indium/sulfur colloid US Targeted assessment Plain film Excellent osseous detail Key in initial evaluation of joints Assess for fractures/dislocations Arthritis Osseous disorders/ mineralization Hardware evaluation CT Excellent osseous detail Good soft tissue detail Useful for postoperative evaluation, complex fractures, occult fx, intraarticular loose bodies,fluid collections, soft tissue gas Limited assessment of menisci, labra, ligaments, tendons, marrow assessment MRI Superior soft tissue detail tendons, ligaments Superior marrow evaluation Edema, contusions, occult fx, osseous lesions Limited osseous detail evaluation Ferromagnetic susceptibility artifact Motion Claustrophobic pt – can sedate patients Optimizing clinical diagnosis of MSK disorders with imaging Joint pain w/ negative findings/xray does not correlate hx decreased ROM/ weakness/ impingement Plain film best initial test MRI to assess soft tissue Tear vs Tendinosis Full thickness tear Partial articular surface tear Rotator cuff teas Patient has pacemaker – can we still evaluate rotator cuff ? YES Arthrogram CT arthrogram adds anatomy Knee pain, negative xray Next step –MRI Menisci Ligaments Tendons My patient has metal hardware, can I still order an MRI Is it useful? Metal Artifact Reduction Sequences (MARS) Assess soft tissue, effusions, fluid collections Tendons, ligaments Osteolysis adjacent to hardware Assessment of internal derangement if not joint replacement How do I order it? eg – MRI right hip MARS protocol Tumor/mass Mass/lump felt by clinician or patient What to order first? Xray – best initial step Extremity soft tissue tumor/mass Abnormal xray/ normal xray If it can be normal, why order it? Can aid in assessment of mass – calcifications, bone involvement What to order next? MRI How to order it? MRI w/ & w/o contrast tumor/mass protocol e.g. MRI right lower extremity tumor/mass protocol w & w/o contrast Capsule marker placed around mass If mass not initially found by patient, show exact location so the can reproduce site for exam Identifies target mass vs. additional not clinically detected lesions Fall, back pain, age indeterminate compression fracture on xray What if patient has pacemaker and there is a compression fracture deformity? Bone scan Imaging of spine Back pain Xray initial best test Imaging of spine CT spine– no IV contast MRI spine w/o Limited in assessment of spinal stenosis most routine work for LBP, radiculopathy MRI spine w/ & w/o Post op follow up Oncology Can’t do MRI, but I suspect central canal stenosis CT myelogram Low back pain, radiculopathy CT myelogram Good option when can’t do MRI Pacemaker Post op metal Invasive Contrast injected into thecal sac Nuclear Isotope Studies Bone scan – infections, osteomyeltits, stress/insufficiency fx “ diffuse bone pain” Limited spatial resolution – compliment with plain films Indium/sulfur colloid – infections esp with hardware Gallium- infections I want to assess for osteomyeltis but my patient has a pacemaker No hardware Plain film 3 phase bone scan Indium scan (gallium in spine) Hardware Plain film 3 phase bone Induim/sulfur colloid scan Marrow displacement I want to assess for hardware loosening vs infection Plain film 3 phase bone scan Induim/sulfur colloid scan Marrow displacement Objectives: Review common musculoskeletal imaging modalities Discuss advantages and disadvantages of imaging tests Discuss use of contrast agents Discuss imaging test approach to optimize clinical diagnosis of musculoskeletal disorders Take away pearls Knowing what a test can and can not assess will help in optimal test ordering Xray most useful initial imaging modality MRI’s best done if targeted – soft tissue mass, joint, limb Protocols differ Many exams can be substituted to get a diagnosis if a condition prevents a desired exam Talk to your radiologist Do I Need Contrast? Optimal for Mass/oncology “Itis” –infection, abscess Post op Lumbar spine Not needed MRI/CT of joints (not suspecting infection or mass) When in doubt, let the radiologist figure it out Talk to your radiologist Questions?