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Functions of Phospholipids and Glycolipids 1. Transport of lipids in the blood. 2. Formation of tissue fat. 3. Anchoring certain cell surface proteins like, alkaline phosphatase, lipoprotein lipase and acetylcholine esterase. 4. Antigenic determinant and cell interactions. 5. Source of arachidonic acid. 6. Hormone second messenger. 7. Hypersnsitivity and inflammatory reactions. 8. Blood clotting. 9. Solubility of cholesterol in bile. Phospholipids Glycerophospholipids Phosphatidic acid Lecithins Cephalin Cardiolipin Sphingophospholipids Plasmalogens PAF Ceramide Sphingomyelins Platelet Activating Factor (PAF) *It is a choline plasmalogen with palmityl alcohol In position 1 and acetyl radical in position 2 of glycerol. *It is synthesized and liberated by granulocytes and macrophages in response to specific stimulation by the specific antigen. Functions Of PAF 1- It is a mediator of acute inflammatory reactions, hypersensitivity reactions and anaphylactic shock. 2- It produces edema, vasodilatation and bronchospasm. 3- It activates neutrophils and macrophages to produce superoxide radicals that help in killing bacteria. 4- It causes platelet aggregation as low as 10-11 mol/l