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Superbugs Starter Match the following keywords with your definition sheet Resistant Antibiotic Superbug Bacteria Objective Understand the causes, affects and solutions to the problems of bacterial superbugs Outcomes State the definition of the keywords Describe the consequences of overuse of antibiotics Describe how strains of bacteria, including MRSA, have developed resistance to antibiotics Can link the development of MRSA to the theory of natural selection. Superbugs Keyword Definition Single-celled microorganisms The capacity of an organism to defend itself against a disease a strain of bacteria that is resistant to most antibiotics A substance or compound that kills, or inhibits the growth of, bacteria. Superbugs Keyword Definition Bacteria Single-celled microorganisms Resistant The capacity of an organism to defend itself against a disease Superbug a strain of bacteria that is resistant to most antibiotics Antibiotic A substance or compound that kills, or inhibits the growth of, bacteria. This little bacteria can..... MRSA under a microscope ....cause this MRSA http://www.nhs.uk/conditions/MRSA/Pages/Introduction.aspx Read the article ‘What is MRSA’ to answer the following: 1. 2. 3. 4. 5. 6. What does MRSA stand for? Where can you find MRSA? How is MRSA transmitted? Why is MRSA resistant? What can MRSA cause? What are the different causes of MRSA? MRSA What does MRSA stand for? Methicillin-resistant Staphylococcus aureus Where can you find MRSA? Many people naturally carry it on their throat, nose and skin What can MRSA cause? A mild infection such as pimples and impetigo, if it penetrates get through the skin and cause serious infection elsewhere in the body such as sepsis (blood infection) and pneumonia. Natural Selection Variation exists in a population due to mutations in their genes The organisms with the most appropriate characteristics to their environment will survive and reproduce The ‘useful’ gene that enabled them to survive will be passed on to the next generation Natural Selection Different Cheetahs within a population could run at different speeds due to variations (caused by mutations) in their genes. The fastest Cheetahs were able to catch more prey (Gazelles)therefore able to survive and reproduce. The ‘useful’ genes that enabled them to run faster than others in the population, were passed on to the next . Natural Selection of Bacteria Natural Selection of Bacteria Apply your knowledge of natural selection and explain how bacteria develop resistance to antibiotics A. Draw a flow diagram to show how can a strain of Staphylococcus aureus can become a resistant strain or MRSA B. Write a paragraph describing why MRSA is a good example of natural selection in action. (6 marks) Plenary Peer mark your partners work and give them a mark out of 4 for each question Give them a target for improvement Question A Variation exists in S.aureus population due to mutations in their genes When S.aureus are exposed to an antibiotic, nonresistant pathogens are killed, the few with resistance will survive The resistant S.aureus will reproduce and pass on the resistant gene to all offspring (bacteria reproduce asexually) S.aureus will become MRSA when exposed to a high number of different antibiotics and the above is repeated Question B Natural selection states that only those that are best adapted to their environment will survive (1) MRSA has adapted to its environment, by being able to resist various antibiotics (1) Non-resistant strains, like S.aureus, die out (1) As they are not well adapted to their environment (1) All bacteria are able to reproduce quickly (1) Therefore mutations are seen in whole populations very quickly (1)