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GMO genetically modified organisms What is a GMO? • An organism whose genetic characteristics have been altered using the techniques of genetic engineering. • A Closer Look Scientists today have the ability to modify the genetic makeup of plants and animals, and even to transfer genes from one species to another. Not since nuclear power has a technology been so controversial, with opponents concerned about the creation of so-called Frankenfoods and proponents promising a better tomorrow through science. • The term genetically modified organism (GMO) is used to refer to any microorganism, plant, or animal in which genetic engineering techniques have been used to introduce, remove, or modify specific parts of its genome. Examples include plants being modified for pest resistance; lab animals being manipulated to exhibit human diseases, such as sickle cell anemia; and even glowing jellyfish genes inserted in a rabbit for an art piece. GMOs show great promise in improving agriculture. • Plants could be engineered to better tolerate temperature or weather extremes, to contain various vitamins, or to dispense medicines and vaccines. Many think genetically modified foods have the potential to end world hunger. On the other hand, there are fears that the disease- or pest-resistant genes inserted into crop plants might escape into other plants, creating hard-tocontrol superweeds. There is also the possibility of unexpected effects on other flora and fauna, the risk of agriculture being controlled by biotech companies, and, as with any new technology, problems that are yet unknown. Applications of GMO AGRICULTURE BACTERIA bacteria introduced into the soil improve its characteristics (eg nitrogen-fixing bacteria) or protect plants from frost. MYCETES PLANTS ANIMALS NUTRITION improved agronomic practices: eg. plants tolerant to water stress or salinity, crops tolerant to specific herbicides introduction of resistance traits specific: eg. plants resistant to insects or viruses energy production: varieties with higher heating power and require less chemical inputs can be used even on marginal areas MEDICINE INDUSTRY production of medicines such as insulin Biological cure production of enzymes used in the food industry, improvement of processes of fermentation production of biomedicine improvements in nutritional and organoleptic qualities: eg. rice high in betacarotene, tomatoes ripening slowed production of drugs / compounds in the plant (molecular farming): lowcost production of pharmaceutical substances and chemical properties, reduced waste industrial chemicals improvement of the characteristics required at the industrial level of the raw materials (eg poplar, with a rate of less lignin to facilitate the process of manufacture of paper pulp) phytoremediation animal products with better nutritional and organoleptic characteristics: eg. milk with higher content of casein, lactose-free milk production of biomedicine models for research on human disease (eg the oncotopo) animal organ donors for xenotransplantation synthesis of molecules of interest to the industry GOM’s food dangers • The most common problem caused by consumption of GOM products seems to be thus chronic inflammation of the intestine, because the genetically modified material interferes with the natural process of absorption of nutrients and the production of enzymes necessary for a healthy digestion. Other effects are related to the fact that a large amount of our DNA is the result of a transfer of viral DNA occurred more than 40 million years ago, and a further shift could cause mutations that occur with psychiatric conditions. The worldwide distribution • Throughout the world there are over 114 million hectares of crops genetically modified plants, more than half of which are located in the United States (51%) as well as 87% of them are on the American continent. Some 99% of the crop is concentrated in few countries: the United States, Canada, South America (Argentina, Brazil and Paraguay), India, China, and South Africa. In some European countries like France, Spain, Portugal, Poland, Germany, Slovakia, Czech Republic and Romania allowed to grow GM crops, while in others (Austria and Greece) is prohibited. Still different is the situation in Italy, United Kingdom, Denmark, Sweden, Finland, Hungary and Slovenia, where the law prohibits the cultivation of GM plants, but not their import. The argument about GMOs • In addition to environmental and health risks, assessed through scientific research, the introduction of genetically modified organisms (particularly in the food industry) may have potential economic and social development of the agricultural economy in areas where they are grown. All these different elements of risk are the focus of heated debates at national and international levels, often creating strong polarization in the public debate and raising also in the scientific community. • Among the topics discussed, as well as the feared risks described above, there is the legitimacy of patenting genetic sequences and genetically modified organisms, can now practice in most developed countries and engaged in genetic research, though with several limitations, and the ethical implications related to the use of engineered animals for experimental purposes (for example the oncotopo), or the use of human embryonic cells for research purposes. • Dalila Santoro 4B • Marialaura Abbadessa 4B • Francesco Zippo 5B