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Virulence Factors allow bacteria to cause disease. They include: •Attachment (via adhesins) •Colonization •Invasiveness •Toxins & Enzymes Virulence Factors Invasiveness: Hyaluronidase Coagulase Streptokinase (dissolves Clots) Membrane disrupting Toxins: e.g., hemolysins; leukocidin, phospholipase (removes charged head groups from phospholipids as is seen in gas gangrene/Clostridium perfringens a-toxin Classes of toxins Neurotoxins Enterotoxins Cytotoxins
