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Chromosomes and Cell Reproduction Genetic Continuity: What does it mean? “Reproduction of offspring with the same features as the parent” Every new cell needs to have an exact copy of its parents DNA. New exact copies are created when cells reproduce. The Cell Cycle The life of a cell is composed of 2 main parts: 1) Interphase: the non-reproductive stage where cell undergoes normal cell function. 2) Mitosis: Series of events that make up the reproductive stage of cell life. Cycle End Mitosis Interphase Cycle Start Interphase: non-reproductive portion of cell cycle -cell undergoes normal functions -nuclear material (DNA) is duplicated during late interphase -cell organelles are also duplicated WHY are the DNA and organelles duplicated? Interphase Animal Plant Prophase: the start of mitosis -nuclear membrane breaks down -chromosomes coil thicker,shorter -spindle fibers form, will anchor chromosomes to poles of cell Why does the nuclear membrane need to break down? Why does DNA have to form chromosomes for cell division? Prophase Animal Plant Metaphase: -chromosome pairs migrate toward equator of cell -centromere of each chromosome firmly attaches to spindle fiber What is the purpose of a centromere? Metaphase Animal Plant Anaphase: -centromeres split -replicated chromosomes move apart -cell membrane begins to pinch inward -in plants, new cell wall starts to form, called the “cell plate” Anaphase Animal Plant Telophase: -cell division is almost complete -spindle fibers dissolve -chromosomes uncoil, become longer and thinner again. -cytokinesis begins Telophase Animal Plant Cytokinesis: -the cytoplasm of the cells is divided. -new cell membrane is formed, and encloses both cells. -in plants, new cell wall is complete -two genetically identical “daughter cells” are formed Chromosome Number -Each species of organism has a specific number of chromosomes. Example: Humans have 46 chromosomes, Fruit flies have 8 chromosomes Most organisms have their chromosomes arranged in pairs. Cells with 2 of each chromosome are called diploid. The diploid number of chromosomes is represented by 2n, where n is the number of different pairs of chromosomes Example: Humans have 46 chromosomes, arranged in 23 pairs. n=23, so 2n= 46 Fruit flies have 8 chromosomes, arranged in 4 pairs. n= 4, so 2n=8 In diploid cells, each member of a pair has the same basic structure. The 2 members of a pair are called homologs, and the pair is called a homologous pair Example: Each member of a homologous pair may carry the gene for eye color: 1 member may carry the gene for blue eyes, the other member may carry the gene for brown eyes. The combination of both genes will determine the trait that is expressed. Normal Male Human Karyotype Meiosis: Cell division that reduces the chromosome number by 1/2. The result is cells with the haploid number of chromosomes. The haploid number is represented by n. Example: In humans, the diploid number is 2n, or 46 The haploid number is 23. Meiosis makes it possible for sexual reproduction, and therefore the recombination of genes, to occur. Sex cells are called gametes, and are either sperm from males, or eggs (ovum) from females. Sperm and eggs are both haploid.