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Microbial Genetics - DNA Transfer Review of Information Transfer in Cell Recombination Transfer of DNA &Genetic Recombination in Bacteria – Conjugation – Transformation – Transduction Microbial Genetics - DNA Transfer Microbial Genetics - DNA Transfer Recombination – process by which DNa is broken and repaired resulting in an exchange of DNA between two DNA molecules to form new combinations of genes Eukaryotic - crossing over during meiosis Prokaryotic - occurs when DNA is transfered from one cell to another (transfer from a doner to a recipient) Microbial Genetics - DNA Transfer Genetic Recombination Microbial Genetics - DNA Transfer Conjugation Microbial Genetics - DNA Transfer Normal or Low Frequency Conjugation Microbial Genetics - DNA Transfer High Frequency Conjugation Transformation Transduction Microbial Genetics - Regulation Three types of regulation – Constitutive - gene is always turned on – Repression - gene is normally turned on but can be turned off in response to a metabolic signal – Induction - gene is normally turned off but can be turned on in response to a metabolic signal Microbial Genetics - Regulation Types of Regulation of mRNA synthesis – Induction - lac operon – Repression - trp operon Microbial Genetics - Regulation