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Macromolecules 1. Carbohydrates 2. Proteins 3. Lipids 4. Nucleic Acids Monomers and Polymers ONE train car represents a Monomer (one UNIT) Entire TRAIN made up of many MONOMERS is called a POLYMER (MANY units) Monomers of Macromolecules • Carbohydrate – Monosaccharide (glucose) • Proteins – Amino Acids • Lipids – 3 Fatty Acids and 1 Glycerol • Nucleic Acids –Nucleotide ( Phosphate, Nitrogen base, Deoxyribose or sugar) Where is energy stored in a molecule? How is this chemical energy released when the body needs it? ENZYME!!!! ENZYME!!!! (Protein) Where are macromolecules in our bodies? (Lipid) (Protein) (HemoglobinProtein) (Fuel – glucose) (Lipid) All Cells basically Protein) Carbohydrates (Come from Plants) Carbohydrates (C,H,O) Monosaccharides (simple sugars; monomers) (one) (sugar) 1. Glucose: C6H12O6 - (blood sugar, dextrose) 2. Fructose: C6H12O6 - (sugar in fruits, honey) 3. Galactose: C6H12O6 - (sugar in all green leafy plants) Isomers (C6H12O6) 1. Molecules with the SAME ________ but different ________ therefore different functions. Simple Carbohydrates • Simple carbohydrates are broken down quickly by the body to be used as energy. • Simple carbohydrates are found naturally in foods such as fruits, milk, and milk products. • They are also found in processed and refined sugars such as candy, table sugar, syrups, and soft drinks. • The majority of carbohydrate intake should come from complex carbohydrates (starches) and naturally occurring sugars rather than processed or refined sugars. Glucose Sugars! from a plant. Anything that comes Glucose Facts • Glucose is your main energy normally used by the brain. source and only fuel Glucose travels through the body in the blood stream and is often called blood sugar. Energy for Cells C6H12O6 The monosaccharide glucose is the principal energy source for humans and other vertebrates. In the hospital a patient receives intravenous feeding of glucose commonly called "drip" dissolved in a salt solution, the ionic composition of which is approximately similar to those of body fluids. Energy for cells Glucose Indicator for Glucose Fructose Fruit Sugar Galactose Plant Sugar Disaccharides (two sugars) 1. Glucose + glucose maltose (brewing beer) 2. Glucose + fructose sucrose (cane sugar) 3. Glucose + galactose lactose (milk sugar) Polysaccharides (long chains of many sugar monomers) - these sugar polymers are not "sweet" although they are made up by repeating glucose monomers! Disaccharide Glucose + Fructose = Sucrose (monosaccharide + monosaccharide = disaccharide) 3 Disaccharides Maltose Malt Sugar Sucrose Sugar Cane Sugar Lactose Milk Sugar, from hay! Polysaccharides (sugar) • • • • • Starch Cellulose Glycogen Chitin Amylose Polysaccharides (thousands of glucose molecules) Starch Seeds must store Starch for plant embryo Starch Indicator Chitin Glycogen Storage Glycogen is stored carbohydrates found in high levels in the liver and muscle. Glycogen is excess glucose. Cellulose Cellulose FIBER FIBER Structural Support (in PLANTS) Plant stems, composed of vascular bundles (Xylem and Phloem) and rigid stiff cell walls cellulose made up of , provided structural support for plants. Functions of Carbohydrates • • • • • • Fuel for the cells (glucose) Stored energy in plants (starch) Stored energy in muscles and liver (glycogen) Makes up cell wall in plant cells (cellulose) Makes up exoskeleton of arthropods (chitin) Makes fruit and vegetables sweet to the taste. (fructose, sucrose, ect.) Fill in your Charts Macromolecule Element Monomer Carbohydrates MonoC,H, O, Saccharide (glucose) Sugar, any part of Energy for living things. a plant. Fuel of the cells! Blood sugar, fruit sugar, Green plant sugar Maltose, sucrose Lactose Brewing sugar, cane Sugar (sweeter for food), Milk sugar Starch, chitin, glycogen, cellulose Sugar stored in plants, Exoskelton of arthropod, Sugar stored in animals, Makes up cell walls in Plant cells (support) Polysaccharide (many sugars) Functions Glucose, fructose Galactose Monosaccharide (1 sugars) Disaccharide (2 sugars) Examples Problems associated with Carbohydrates • • • • • • • • Diabetes Low blood sugar High blood sugar (hyperglycemia) Depression (carbs are natural downers) Obesity Heart problems Damage to teeth and gums Poor eye sight • • • • • • • • • High Blood Pressure Accelerated aging Scalp infections (hair loss) Weakened Immune System Encouraging growth of “bad bacteria” Cancer Fatigue (sleepiness) Brain fog (poor memory) Intestinal bloating and gas Low Blood Sugar High Blood Glucose Gestational Diabetes How to maintain Homeostasis if a diabetic! Galactosemic Lactose Intolerance • Many people who have gas, belly pain, bloating, and diarrhea suspect they may be lactose-intolerant. The best way to check this is to avoid eating all milk and dairy products to see if your symptoms go away Processed Carbohydrates (Refined Grain) • The process of refining wheat involves the removal of the starchy endosperm away from the bran and germ, which also strips away the portions of vitamins & minerals essential for health. • The vitamins & minerals stripped away include: • • • • • • • • • • 60% of the calcium 85 % of the magnesium 77% of the potassium 78% of the zinc 68% of the copper 76% of the iron 86 % of the manganese 40% of the chromium 48 % of the molybdenum Nutrients including chromium, magnesium & zinc are vital in assisting the body to properly use carbohydrates including grains for fuel. Lipids Monomers of Lipids Lipids Functions of Lipids Examples of Lipids Saturated Fats Summary of Saturated and Unsaturated Fats Hormones that are Lipids Lipid Hormones Lipids in Membranes Cholesterol (lipid) Problems with to much FAT Some Lipids (fat) can be a problem Proteins Protein Protein Functions Structures of Proteins Indicator for Protein Macromolecule Indicators Hemoglobin (Protein) Chain of Amino Acids Makes A Protein. Hemoglobin carries O2 in the blood to all cells in the Body. Enzymes Enzymes (purple) act as Catalyst to speed up chemical reactions. Protein Toxins Snake Venom Defensive Protein • Antibodies, also called immunoglobulins, are large Yshaped proteins which function to identify and help remove foreign antigens or targets such as viruses and bacteria. Every different antibody recognizes a specific foreign antigen. Transport Proteins Structural Support (in animals) Extracellular matrix is something that cells make and spit outside of the cell to provide protection, strength, structure, and other functions to the animal or plant cells. Extracellular matrix is not Cytoskeleton (Protein) made up of cells; it is made by cells (usually in the Golgi and ER) and shipped outside the cell via exocytosis. Protein Examples of Protein: Hair, feathers, wool, fur, claws, horns, fingernails, Hoofs, toenails, keratin. Silk (Protein) Production of Insulin Biotechnology Application Of using transgenic Bacteria (recombinant DNA) To make a very needed Protein (human insulin) Normal Insulin Production Nucleic Acids Monomer of Nucleic Acids Nucleotide