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Traumatic Brain Injury A Case Study Lisa Randall, RN, MSN, ACNS-BC RNSG 2432 Demographics/CC 23 y.o. AAM Auto vs. ped 8/10/08 HPI Dancing on I-35 under the influence of crack cocaine and ETOH. Hit by 2 cars > 50mph GCS 12 on arrival, but declined to 4 – Eyes 4>1 – Verbal 3>1 – Motor 5>2 History PMH – Denies, but GSW (metallic pellets CXR) PSH – Denies Social Hx – Single, no children, unemployed, unfunded – +ETOH, +amphetamines, +cannibis – Recently released from jail for drug possession Meds – Denies Diagnostics Diagnostics Focused A/P R frontotemporoparietal SDH – Craniectomy – EVD – Monitor/treat ICP Paraplegia/paresis L2 burst fracture c subluxation L2-L3 T11 lamina/TP fracture – T10-L3 posterior fusion when stable – PT/OT/ST…rehab A/P con’t 10th & 11th rib fractures R femur fracture Acetabular fracture Mediastinal hematoma Post-Op Post-Op Nursing Concerns Neuro checks/VS q1h ICP monitoring – Mannitol – CSF drainage CPP monitoring – IVF – Vasopressors MAP monitoring Sedation/analgesia Seizure prophylaxis Infection prophylaxis Skin care Interdisciplinary Collaboration Trauma Pulmonary/CC Orthopedics ID SW/CM Nursing PT/OT/ST/RT WOCN Dietary Evaluation Rehabilitation Assessment – Decreased short term memory – Paraparesis DF 2/5, PF 2/5, HF 4-/5 Cranioplasty Epidemiology of Head Trauma Occurs every 15 seconds 500,000 annual ED visits Most common causes: MVAs, falls, assaults Males 15-24, elderly > 75 Accounts for 40% of traumatic deaths Pathophysiology of TBI 1st – Primary Injury: initial insult … i.e. from bleed Second Secondary Injury: delayed injury from hypoxia, ischemia, and release of neurotoxins Excitatory amino acids can cause swelling and neuronal death Endogenous opioids cause increased metabolism, using glucose supplies Increased ICP, especially > 40 leads to brain hypoxia, ischemia, hydrocephalus, herniation Hydrocephalus: clotted blood obstructs CSF outflow tracts and absorption of CSF, disrupts blood-brain barrier Head Trauma Concussion Contusion Epidural hematoma (EDH) Subdural hematoma (SDH) Basilar skull fracture Diffuse axonal injury (DAI) Epidural Contusions Basilar skull fracture Depressed skull Fracture Types of Injuries Mild Traumatic Brain Injury: – Concussion: brief change in mental status with axonal swelling Moderate to Severe Brain Injury: – Contusion: “bruising” – Fractures: linear,comminuted, depressed, basalar – Bleeds: epidural, subdural, intracerebral Mild Traumatic Brain Injury Period of LOC < 30 mins with a GCS of 13-15 after this LOC 2. Amnesia to the event 3. Alteration in mental status at the time of the event (dazed and confused) 1. Types of Concussion Grade I (confusion, no amnesia, no LOC) – Remove from activity (may return when asymptomatic) – 3 concussions in 3 months: no activity that risks head trauma for 3 months Grade II (confusion and amnesia) – – – – Remove from activity for day Recheck in 24 hours No activity for 1 week Two grade II concussions in 3 months, no activity for 3 months Grade III (LOC) – To ED for CT – Symptom free for 2 weeks, then another 30 days – Two grade III concussions, no activity for 3 months Post-Concussive Syndrome Somatic symptoms: headache, sleep disturbance, dizziness, vertigo, nausea, fatigue, sensitivity to light or noise Cognitive: attention, concentration, memory problems Affective: irritability, depression, anxiety, emotional lability Moderate and Severe Brain Injury Contusion Small bleeds Cerebral Edema Deficits are based on lobe involved Fractures Linear Comminuted Depressed Skull Fracture 95% go to surgery Antibitoics for infection Brain tissue is involved Treatment for CSF leak Epidural Hematoma Laceration of dural arteries or veins Classically laceration of middle meningeal artery Temporal bone fractures “Lucid interval” followed by rapid deterioration Acute bleed Subdural Hematoma 60-80% mortality Tearing of bridging veins, pial artery, or cortical veins Acute vs chronic Traumatic Subarachnoid Hemorrhage Lacerations of vessels in subarachnoid space TSAH SAH Intraventricular and Intraparenchymal Hemorrhage Intraventricular hemorrhage – Very severe TBI – Poor prognosis Intracerebral hemorrhage – Parenchymal injuries from lacerations or contusions – Large deep cerebral vessel injury Coup and Contrecoup Injuries Coup: direct skull impact Contrecoup: opposite side of impact Due to negative pressure forces causing both vascular and tissue damage DAI Diffuse Axonal Injury: secondary injury involving white matter, progressing over days Neurologic Exam Decreased neurologic function is best predictor of brain injury Pay attention to cranial nerves Management of Acute Brain Trauma Labs: CBC, electrolytes, type and screen, tox and ETOH screen CT Brain CT angiography or cerebral angiography (penetrating) MRI contraindicated if metallic fragments Management Continued. .. Intubate GCS 8 or less or airway protection issue (Cricothyroidotomy if necessary) Maintain BP 90 mmHg systolic C-spine precautions Tetanus prophylaxis Sterile dressing to wounds Antibiotics in penetrating injury ICP Management is the Key ICP monitor in patients with GCS < 8 Hyperventilation not routinely recommended Elevate head of bed to 30 degrees Sedation Propofol Barbiturate Induced Coma Contraindicated in hypotension Mannitol Reduces ICP by reducing blood viscosity, improves cerebral blood flow Serum osmolality should not be > 320 Bolus dosing To Image or Not to Image? GCS < 15 Intoxicated Age > 55 or < 2 Amnesia to events Witnessed LOC (> 15 minutes) Repeated vomiting Evidence of basilar skull fracture Inability to recall 3 of 5 objects Coagulopathy Penetrating head injury Ventriculostomy Evidenced Based Medical Guidelines for TBI Management BP and oxygenation Hyperosmolar therapy ICP monitoring CPP Infection prophylaxis DVT prophylaxis http://youtu.be/YQ609Tk-qQI PbtO2 Analgesic/sedatives Nutrition Antiseizure prophylaxis Hyperventilation Steroids Hypothermia References AANN Core Curriculum for Neuroscience Louis, MO. Nursing, 4th Ed. 2004. Saunders. St. Davis, F.A. (2001). Taber’s Cyclopedic Medical Dictionary. F.A. Davis, Philadelphia. Greenberg, Mark. (2006). Handbook of Neurosurgery. Greenberg Graphics, Tampa, Florida. Lewis, S., Heitkemper, M., O’Brien, P., Bucher, L. (2007). Medical-Surgical Nursign. Assessment of Management of Medical Problems. Mosby Elsevier, St. Louis, Missouri Silvestri, Linda. (2008). Comprehensive review for the NCLEX-RN Examination. Saunders Elsevier, St. Louis, Missouri.