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Cellular Respiration 1. Harvesting Chemical Energy a. Plants and animals both use products of photosynthesis (glucose) for metabolic fuel b. Heterotrophs: must take in energy from outside sources, cannot make their own e.g. animals c. When we take in glucose (or other carbs), proteins, and fats-these foods don’t come to us the way our cells can use them 2. Cellular Respiration a. Cellular Respiration is the process that releases energy by breaking down food molecules in the presence of oxygen. b. These reactions proceed the same way in plants and animals. c. 6O2 + C6H12O6 6CO2 + 6H2O + ATP Energy d. Oxygen + Glucose Carbon Dioxide + Water + Energy 3. Cellular Respiration Overview a. Breakdown of glucose begins in the cytoplasm: the liquid matrix inside the cell b. At this point life diverges into two forms and two pathways i. Anaerobic cellular respiration (aka fermentation) ii. Aerobic cellular respiration Section 9-1 Chemical Pathways Glucose Glycolysis Krebs cycle Fermentation (without oxygen) Electron transport Alcohol or lactic acid 4. Glycolysis a. Series of reactions which break the 6carbon glucose molecule down into two 3-carbon molecules called pyruvate b. Process is an ancient one-all organisms from simple bacteria to humans perform it the same way c. Yields 2 ATP molecules for every one glucose molecule broken down d. Yields 2 NADH per glucose molecule Section 9-1 Glucose Glycolysis 2 Pyruvic acid To the electron transport chain 5. Fermentation a. Releases energy from glucose without the presence of oxygen. b. There are two types of fermentation: alcoholic and lactic acid. i. Alcoholic fermentation is done by yeasts and some microorganisms. It produces alcohol & Carbon Dioxide ii. Lactic Acid is produced by muscles during rapid exercise when the body cannot supply enough oxygen. 6. Anaerobic Cellular Respiration a. Some organisms thrive in environments with little or no oxygen i. Marshes, bogs, gut of animals, sewage treatment ponds b. No oxygen used= ‘an’aerobic c. Results in no more ATP, final steps in these pathways serve ONLY to regenerate NAD+ so it can return to pick up more electrons and hydrogen in glycolysis. i. End products such as ethanol and CO2 (single cell fungi (yeast) in beer/bread) or lactic acid (muscle cells) Section 9-1 Lactic Acid Fermentation Glucose Pyruvic acid Lactic acid 7. Aerobic Cellular Respiration a. Oxygen required=aerobic b. 2 more sets of reactions which occur in a specialized structure within the cell called the mitochondria i. Kreb’s Cycle ii. Electron Transport Chain Cellular Respiration: An Overview Section 9-1 Mitochondrion Electrons carried in NADH Pyruvic acid Glucose Glycolysis Krebs Cycle Electrons carried in NADH and FADH2 Electron Transport Chain Mitochondrion Cytoplasm 8. The Krebs Cycle a. During the Krebs Cycle, pyruvic acid is broken down into carbon dioxide in a series of energy-extracting reactions. b. Citric Acid is created in this cycle thus giving it the nickname Citric Acid cycle. c. Net ATP Production is 2 ATP. 8. Kreb’s Cycle c. Completes the breakdown of glucose i. Takes the pyruvate (3-carbons) and breaks it down, the carbon and oxygen atoms end up in CO2 and H2O ii. Hydrogen and electrons are stripped and loaded onto NAD+ and FAD to produce NADH and FADH2 d. Production of only 2 more ATP but loads up the coenzymes with H+ and electrons which move to the 3rd stage 9. Electron Transport Chain a. The electron transport chain uses the high-energy electrons from the Krebs Cycle to convert ADP to ATP. b. Total ATP 32. 9. Electron Transport Chain c. Electron carriers loaded with electrons and protons from the Kreb’s cycle move to this chain-like a series of steps (staircase). d. As electrons drop down stairs, energy released to form a total of 32 ATP e. Oxygen waits at bottom of staircase, picks up electrons and protons and in doing so becomes water Section 9-2 Electron Transport Chain Electron Transport Hydrogen Ion Movement Channel Intermembrane Space ATP synthase Inner Membrane Matrix Mitochondrion ATP Production 10. Energy Tally a. 36 ATP for aerobic vs. 2 ATP for anaerobic i. Glycolysis 2 ATP ii. Kreb’s 2 ATP iii. Electron Transport 32 ATP i. 36 ATP b. Anaerobic organisms can’t be too energetic but are important for global recycling of carbon Aerobic Cellular Respiration Section 9-2 Glucose (C6H1206) + Oxygen (02) Glycolysis Krebs Cycle or Citric Acid Cycle Electron Transport Chain Carbon Dioxide (CO2) + Water (H2O) 11. Energy & Exercise a. Quick energy – Lactic Acid fermentation is used to get quick energy and gives off lactic acid as a by product, thus the muscle pain. b. Long-Term Energy – Use cellular respiration to produce energy. Exercising or activities that last for at least 15 to 20 minutes. Best form for weight control. 12. Comparing Photosynthesis & Respiration Photosynthesis Cellular Respiration Function Energy Storage Location Chloroplasts Energy Release Mitochondria Reactants CO2 and H2O Products C6H12O6 and O2 C6H12O6 and O2 CO2 and H2O Equation 6CO2 + 6H2O C6H12O6 + 6O2 C6H12O6 + 6O2 6CO2 + 6H2O