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CIRCULATORY SYSTEM Blood Blood vessels Heart Lymph system Other animals Composition of Blood White blood cells Red blood cells Blood Plasma Cells Protein Water soluble frinogen Ions, gases Enzyme Hormone Albumin Soluble food Erythrocytes (red blood cell) Leucocytes (white blood cell) Blood platelets Blood Plasma Plasma is approx. 55% by vol. and contains WATER (as a solvent) SOLUBLE SUBSTANCES nutrients (eg. glucose, amino acids) wastes (eg. CO2, urea, excess minerals) plasma protein (blood clotting) hormones (internal messenger) antibodies (defense mechanism) What is the cells? A. Neutrophil: Most common type; constitutes 40-75% of circulating leucocytes. Highlylobulated nucleus (polymorphonuclear). Cytoplasm contains light purplish granules (large lysosomes). B. Eosinophil: Accounts for 1-6% of circulating leucocytes. Characteristically a bilobed nucleus. Cytoplasm packed with large eosinophilic (dark pink; orange in this photo) granules. C. Basophil: The least common leucocyte; <1% of circulating white blood cells. Has a bilobed nucleus, often obscured by the numerous dense, basophilic (dark blue/purple) granules. D. Lymphocyte: The smallest leucocyte. Makes up to 20-45% of circulating white blood cells. Has a round, densely-stained nucleus and a small amount of lightly-stained non-granular cytoplasm. E. Monocyte: Constitutes 2-10% of leucocytes. Nucleus is large and indented, often with a horseshoe or bilolobed appearance. Cytoplasm is very pale and non-granular in appearance. F. Platelets: Small fragments of larger cells (megakaryocytes) present in the blood in large numbers 150,000 - 400,000 per ml. Also known as thrombocytes. Important for blood haemostasis. Red Blood Cell What is the features and functions of red blood cells Question: what is conclusion? Functions of Blood Transport Nutrients Gases Wastes Heat antibodies Hormones Defense White blood cell Blood clotting BLOOD PIGMENT Contain Iron2+ Protein O2 Transport 100% 0% % saturation of haemoglobin with O2 Hb + 4O2 HbO2 Lung Tissue Oxygen Tension (kPa) 100% 0% % saturation of haemoglobin with O2 Bohr Effect CO2 Tension 2 kPa 5 kPa Oxygen Tension (kPa) 8 kPa CO2 Transport Overall gases transport BLOOD GROUP The ABO Blood Group Agglutination Reaction Artery and Vein Vein transport mechanism Capillary Capillary system Circulatory system Heart Cardiac muscle valve Nodes in heart Sino-atrial node Atrial-ventricular node Bundle of His purkinje fibers Pulse formation Blood pumping Animation Pressure change in heart ECG Mixed diagram ECG Abnormal beat Control of Heart Beat Affected by various factors e.g. PCO2, blood pressure, pH Affecting heart beat rate and volume Controlled by nerves and hormone Control of heart rate Carotid body Lymphatic system Circulatory System in other organism open circulatory system Open circulatory systems (evolved in insects, mollusks and other invertebrates) pump blood into a hemocoel with the blood diffusing back to the circulatory system between cells. Blood is pumped by a heart into the body cavities, where tissues are surrounded by the blood. Closed Circulatory System Closed circulatory systems (evolved in echinoderms and vertebrates) have the blood closed at all times within vessels of different size and wall thickness. In this type of system, blood is pumped by a heart through vessels, and does not normally fill body cavities. Fish Lung fish Amphibian Reptile Mammals