Download For Infornation: Andrs Jowers lvlanager, News Bureau (619)

For Infornation:
Andrs Jowers
lvlanager, News Bureau
(619)457-8290, 455-8133
FOR IMI{EDIATE RM,E,ASE
#82388-4
Scripps Cl-inic resuunes clinical
of experimental
Lunq cancer treatrent
IA ,JOLLA,Aug. 23 -resuning its
trial
clinical
Scrilps
trial
and Research Foundation is
Clinic
of an experirental
phase of the trial,
Like the initial
this
treatment for lung cancer.
stage is confined to
with non-snall celI lung cancer - the npst conunontype, accounting
lntients
for threequarters
of the l-50,000 cases diagnosed each year in this
country.
Patients
Itre trial
interested
will
conjugate
Monoclonal- antibodies
out and bind to specific
anLibody used in this
antibody-drug
killing
are antibodies rade in the laboratory that seek
cells - in this case, lung cancer celIs. Itre
study is ctrsnically
&ug,
cells
of a
in hurnns.
combined with the
Once injected'
methotrexate.
conjugate should deliver
nalignant
(619)455-8860.
continue to evaluate the safetv and effect
nronocl"onal antibody-drug
chsnotherapeutic
in the stuQy should call
the monoclornl
the drug directly
without daneging nornal tissue.
(l'iore)
to the twror,
thus
Page 2
Aug. 23' 1988
#82388-4
The antibody used in the trial
Institute
of Scripps Clinic
I KSI/ , was discovered by Research
investigators.
The antibodlz and antibody-drug
conjugates $/ere produced by Brunswick Technetics,
quantities
for hunnn trials.
and tLre initial
Prelininary
director
oncology division;
Research Institute
in the laboratory
and Dr. Leslie
of Scripps Clinic.
oncology, henatology and
director
of the ctrest and critical
Walker, immunology dj.vision,
Dr. Darlene Elias,
formerly of the
San Francisco, Cardiovascular Research Institute,
the Scripps Clinic
on this
out the stuQy include Dr. Robert
clinical
Dr. Iawrence Kline,
UniversiQr of California,
a ceinvestigator
carrying
of experimental
care medicine division;
has joined
investigations
hunan safety studies have been prcrnising.
The team of investigators
Dillnnn,
San Diegor in sufficient
chest and critical
project.
###
care redicine
division
as