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Analysis of Prescription Drug Regimen Compliance Charles Mason Computer Applications in Medicine REU 2006 University of Virginia Introduction • Project Overview • Software framework, and application to provide analysis of patients’ drug regimen compliance • Previous Work • Amit Phull’s senior thesis • PDA application to remind patients and monitor their compliance Motivation • Monitoring patient compliance with their prescription regimen is a major issue for many different fields of medicine • Electronic Monitoring systems are currently the best way of providing doctor's with accurate information on patient compliance • Current electronic monitoring systems have significant shortcomings Current State-of-the-Art • Medication Events Monitoring System (MEMS) by Aardex • Special containers record when prescription is opened and closed • Separate software used to do basic analysis of the data • Problems • Costly • Containers easily lost Goals • Provide valuable information on patient compliance to the patient’s physician • Provide a file format to store patient compliance data. File format should be easily extendable to include new data • Provide extensible framework for handling patient compliance data • Provide an application to analyze patient compliance data Results • File format for storing patient data: • Created an XML schema which defines a file format for storing data • This file stores a patient’s prescription regimen as well as compliance data for the regimen • File format takes advantage of outside tools to allow for easy modification to store more data Results • Framework for manipulation of compliance data • C# class library • Provides ability to create, manipulate, and save compliance data • Provides methods for performing statistical analysis of the data Results • Analysis application • Windows application written in C# • Provides doctor with information based on analysis of patient compliance • Allows doctor to set analysis parameters allowing the doctor to get fine-grained information • Provides ability to generate graphs from compliance data Demonstration Future Work • Create application for capturing compliance data • Provide further analysis of compliance data