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Complementary and Alternative Medicine
Presentation by:
Terry Chhour
Leah Lopez
Polly Peru
Mark Reyes
Rachelle Sebastian
Learning Objectives:
● Provide current research
information on the potential
scientifically demonstrated
functions of turmeric concerning
its effectiveness on preventing
type 2 diabetes
● Traditional and modern uses
● Impeding its devastating
complications due to turmeric’s
ability to regulate insulin activity
and improve glucose control.
Turmeric
●
Turmeric has been used as an
aromatic spice in Middle Eastern
and Southeast Asian cooking
●
Medicinal instrument in
complementary health practices for
over 6,000 years.
●
Complementary health practitioners
use turmeric in the treatment of
many chronic illnesses such as
diseases of the eye, cancer,
osteoarthritis, ailments of the
digestive system, inflammation,
cardiovascular disease and
diabetes.
Description
● Turmeric is extracted from the rhizome (root) of the plant Curcuma Longa.
➢ The rhizomes are boiled in water, drained, dried, and grounded into
turmeric powder
●
Dried turmeric rhizomes yields 1.5-5% of essential oils, which are responsible
for its aromatic taste and smell
● The yellow color is derived from curcumin, which is the most active component
of the spice, and it makes up 2-5% of the spice.
Traditional and Modern Uses
•Turmeric was regarded as the herb of the sun and
was viewed sacred.
•
Turmeric is a major ingredient of curry
powder and is used in prepared mustard.
A therapeutic agent in both the Indian and Chinese
systems of medicine
❖ Traditional Chinese Medicine (TCM): liver
problems, menstrual difficulties, bloody urine,
hemorrhage, toothache, bruises and sores,
chest pain and colic
❖ Ayurveda: acne, psoriasis, dermatitis, rash,
ulcers, and wounds
•
It is also used extensively in many food
products, including baked goods, meat and
meat products, condiments and relishes, fats
and oils, egg products, soups, and gravies.
•
Turmeric (curcumin) is now marketed in the
form of capsules, tablets, ointments, energy
drinks, soaps, and cosmetics.
•Turmeric in Indian cuisine
• A beauty agent
•
Several clinical reports states that curcumin
even at a high dose of 1000-2000 mg/day
does not produce any harmful effect on
human body
(Choudhary et. al., 2013).
Turmeric in Capsules
● Meriva®, a lecithinized
formulation of curcumin was
well tolerated, and preliminary
findings suggest its
usefulness in the
management of diabetic
microangiopathy
● Super Bio-Curcumin® which
absorbs up to seven times
better than conventional
curcumin represents the most
cost-effective way to achieve
greater peak blood levels
●
Each 400 mg capsule of
Super Bio- Curcumin® is
equivalent to 2,772 mg of a
typical 95% curcumin extract
Effectiveness and Efficacy
•
•
•
•
Improved beta-cell function
Prevented beta-cell degradation
Reduced inflammation by:
• Reducing C-reactive proteins
• Downregulation of
inflammatory cytokines (tnf-a,
leptin, and resistin)
Prevented T2DM on prediabetics
•
(Chuangsemarn et al., 2012)
•
Significant decrease in fasting
blood glucose levels and insulin
resistance
Decrease in serum total levels of:
• FFAs
• TAGs
• Increase in lipoprotein lipase
activity (LPL)
(Na et al., 2013)
Nutrition Facts
100 g of turmeric
contains :
390 kcal
10 g total fat
3 g saturated fat
0 mg cholesterol
0.2 g calcium
0.26 g phosphorous
10 mg sodium,
2500 mg potassium
47.5 mg iron
0.9 mg thiamin
0.19 mg riboflavin
4.8 mg niacin
50 mg ascorbic acid,
69.9 g total carbohydrates
21 g dietary fiber
3 g sugars
8 g protein
Turmeric is also a good source of the ω-3 fatty
acid and α-linolenic acid. Commercial curcumin
contains approximately 77% curcumin, 17%
demethoxycurcumin, and 3%
bisdemethoxycurcumin
Drug Interaction and Side
Effects
● Diabetic Hypoglycemic
Drugs
● Anticoagulant Drugs
● Pregnant and Nursing
Women
Discussion and Conclusion
●
Turmeric is a Middle Eastern, Southeast Asian spice.
●
Turmeric is biochemically, composed of Curcumin,
Demethoxycurcumin, and Bisdemethoxycurcumin;
known as Curcuminoids
●
Benefits:
- Help control blood glucose levels
-Anti- inflammatory, Antioxidant,
-Reduces free fatty acids in serum
-No known adverse effects in high doses
●
Limitations?
- Not bioavailable
- Supplement, rather than food additive
- Most studies are on animals
- Turmeric is not as prevalent in Western
countries
- If it was, shown to be beneficial for Prediabetic and diabetic populations
Questions?