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Adolescent Deliberate Self-Harm: Issues of Development, Culture, Biology, and Treatment Clinical perspectives15 แพทย์ หญิงรัชนี ฉลองเกือ้ กูล โรงพยาบาลศรีธัญญา Deliberate Self-Harm • Deliberate damage to one’s own body tissue without suicidal intent part of larger class of self-injurious behavior • Methods: Cutting/Carving skin Picking at a wound Hitting self Scraping skin to draw blood Biting self Picking skin to draw blood Inserting objects under skin Tattooing self Burning skin Pulling out own hair Erasing skin to draw blood A Typology of Adolescent Self-Cutting based on Frequency Larry K. Brown M.D. Bradley/Hasbro Research Center Prevalence of self-cutters Adolescents: in community 15 % in psychiatric treatment 50 % ศึกษาในเด็ก: 50% กรีดแขนอย่ างน้ อย 1 ครั้ง 30 % กรีดแขนมากกว่ า 4 ครั้ง F>M Frequncy Age Female Race CSA PTSD Condom use Sharing cutting Alcohol use >4 <3 14.9 66 74 63 16 39 20 30 14.9 42 91 34 7 73 5 19 สาเหตุ: 57 % กรีดเมื่อ sad หรื อ upset 35 % กรีดเพื่อ hurt themselves 15 % ทาตามเพื่อน/ to look cool สรุป พบบ่ อยใน adolescent จาก distress & attempt to regulate affect Previous findings: Demonstrate that self-cutting is associated with unprotected sex drug use suicidal behavior history of sexual abuse Recent Data: Frequent self-cutting ( 4 times or more) was associated with unprotected sex and sexual abuse Frequent self-cutters were likely to endorse distress or self-harm as motivations to self-cut Less frequent cutters were more likely to endorse motivations such as the desire “ to look cool” “ because friends do it” Conclusion Infrequent cutting is determined by social, experimental and developmental factors Frequent self-cutting is a method to relieve distress or to inflict self-harm Frequent self-cutters have greater sexual risk and more emotional distress than infrequent self-cutters Deliberate Self-Harm by Adolescents: Potential Impact of The Internet Norman E. Alessi M.D. U. Of Michigan Objective: Examine role of internet in adolescent self-harm behavior Identify sites that both support self-harm and support those that are seeking help Result: No existing medical literature involving Internet & self-harm behavior Google search engine: “Bill of Rights for People Who Harm Themselves” Google search engine: A number of sites dealing with selfcutting as a way of coping with stress often demonstrating techniques of cutting or BLOGS of experience A number of sites provided help for those who want to seek help Bill of Rights for People Who Harm Themselves Conclusion มีการใช้ internet สู งขึน้ ขณะเดียวกันก็มีรายงานการทาร้ าย ตนเองสู งขึน้ แต่ ข้อมูลไม่ เพียงพอทีจ่ ะสรุปความสั มพันธ์ จานวน website ที่เกีย ่ วกับ suicide / self-harm ที่มากขึน้ แสดงถึง concern BLOG may increased danger for a risk teen ผู้บรรยายแนะนาว่ าให้ ถามคนไข้ ว่ามี BLOG ไหม ถ้ ามีขอดู ได้ ไหม Self-Cutting: Where is the Pain? Maryland Pao M.D. NIMH Objective: Review neural circuits involved in normal pain sensitivity and pain processing How they relate to self-cutting behaviors Pain Ass. with actual and potential tissue damage Sensory may last beyond the clinical Early damage in infancy prolonged structure effect Social pain เป็ น pain from social injury or social relationship Self-cutter Early separation and negative response, bullying, sexual/physical abuse disrupted neural circuits ซึ่ งเป็ น social distress and unpleasant มากกว่า physical pain Cut for release distress feel real Treatment assess attachment style assess physical pain history role of CBT teach social skills to help develop better social support Conclusion Self-cutters are reported to experience early separation, bullying in school, and sexual/physical abuse more frequently than non-cutters Traumatic pain events that disrupt normal development of various pain pathways may lead to different structural and functional connectivity in CNS Interventions for Deliberate Self-Harm and Self-Injurious Behavior James C. Harris M.D. Johns Hopkins Hospital Self-Mutilation Superficial – episodic & compulsive; e.g. self-cutting, skin picking (most common in adolescent) Repetitive/Stereotypic – function as self stimulation; e.g. head banging, self biting Severe but infrequent – e.g. self-blinding, amputation; associated with psychosis, intoxication SIB is a model to study gene-brainbehavior relationship SIB,DSH เป็ น stress related behavior disorder สัมพันธ์กบั โรค eating disorder, cluster B personality disorder, PTSD DSH เป็ น coping Activate by emotional arousal Terminate by self injury HPA dysfunction Self-regulation of hyperarousal or dissociative state Polyvagal theory Describes a feedback loop and a schema to understand how environmental context and subjective experience can influence physiological state, and how physiological state can limit ability to deal with environmental challenge Environment challenge Nervous system Safe Social engagement system: I am happy, facial express, make eye contact myelinated vagus Dangerous Defensive strategies: flight, fight, anxious, discomfort Sympathetic Life Threatening Defensive strategies: death feigning, shut down, immobilize, freeze unmyelinated vagus Psychosocial approach social engagement system environmental stressors Enhance communicating skills Develop appropriate self soothing Enhance mood & emotional regulation Monitor drug use & sexual behavior Medication Dopamine antagonist สามารถลด self injury, self biting ( เกี่ยวข้องกับ receptor D1/D5, D3 แต่ receptor D2 ไม่เปลี่ยนแปลง self injury, self biting) ดังนั้น ยาที่ใช้ ควรเป็ นกลุ่ม • Mood Stabilizer • Atypical antipsychotics • Antidepressants • D1 antagonists CLINICAL PERSPECTIVES A presentation on a particular topic related to treatment, research method, service delivery, or clinical care that is evidence-based and includes the “art” and clinical wisdom of the practice of child and adolescent psychiatry.