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2007 HEAVY MENSTUAL BLEEDING Definition Excessive menstrual blood loss which interferes with a woman’s physical, emotional, social and material quality of life, and which can occur alone or in combination with other symptoms. Surgery With HMB alone and uterus no bigger than 10/52 pregnant Endometrial ablation rather than hysterectomy If hysterectomy essential then First line vaginal hysterectomy Second line abdominal hysterectomy Management History Menstrual cycle PMB IMB Vaginal discharge Previous Gynae problems Pregnancy history Management Examination Abdominal exam Pelvic exam if appropriate Swabs if discharge Fbc (not in nice guidelines) Arrange imaging if Second line drug treatment fails Uterus is palpable abdominally or on PV Management Consider endometrial biopsy for Persistent intermenstrual bleeding Women > 45 Treatment failure Ineffective treatment Management No structural abnormality First line drug therapy If fails Second line drug therapy Consider imaging - ultrasound HMB + structural uterine abnormality i.e. Palpable uterus Arrange imaging Treatment If history and investigations indicate that drug treatment is appropriate, drugs should be tried in the following order MIRENA Tranexamic acid, COC, NSAIDS Norethisterone 15mg/day from day 5-26 of cycle or injection of long acting progesterones Management If drug therapy fails and severe impact on life + no desire to conceive + normal uterus or small fibroids < 3cm then Endometrial ablation or Hysterectomy If severe impact on life or fibroids > 3cm then consider Hystercetomy Myomectomy Uterine artery ablation Management If other treatments have failed or are contraindicated or declined Desire for amenorrhoea Fully informed women requests it No desire to retain uterus and fertility Hysterectomy but don’t remove healthy ovaries Not recommended Direct or indirect menstrual blood loss measurement Serum ferritin test Female hormone testing Thyroid testing D&C Not recommended Oral progesterones in luteal phase only Danazol Etamsylate D&C