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ENDOMETRIAL 㖬ぼ㗁㽳⤈ㅠㄪ≗" C NCER 㽳⤈ㅠㄪ≗㗁㱱㽳⤈ㅠㄪㅠ⒬☨㥨⊩㔶ᮣ㱸㮥㨗㽳 ⤈ㅠㄪ≗㗁㯜㢜ㇲ㩂⧣✝ゑ╬⬺㚐⥙✂✚㵒⒱☨ᮣ 㽳⤈ㅠㄪ≗ 㮾㍰ᱨ㮧㫓ⰻ☨㫼ⳑ㦄㖸㸆㱸ㅢ㲓⒌㋜ⶪ⟞╬⬺㚐 (Hormone Replacement Therapy)㱸⤴ᱷ☏㑥ⱅ㚜㐹⌴Ⱓ 㔕⡜ㇲ⒌㋜ⶪ⟞╬⬺㚐ᱨ㽳⤈ㅠㄪ≗☨⏋➂⿔㐲㱸㵜㣐 ⮋ᱨ㮧㫓ⰻⳟ㟠㑌㸆㗁㯜㢜⡜ㇲ㱸➪㈚☨㎷㗀ᱨ☠㺤✂ 㲈☨╬⬺㚐㱱㔩㝛☨㱵㺎㚱㔶ᮣ㐹✚ᱨ➪㈚ⳟ⒱㢜 㽳⤈ㅠㄪ≗☨⟇㦅㯜㚐ᮣ What is Endometrial Cancer? Endometrial Cancer is a cancer that starts in the endometrium, the inner lining of the uterus (womb). It is predominantly due to prolonged exposure to an excess of the female hormone called oestrogen. In the past, this was often a result of oral intake of oestrogen only hormone replacement therapy, the practice which has been stopped by most physicians. Nowadays, the excess oestrogen is usually due to our body’s own production. Certain conditions tend to lead to excess oestrogen production and hence will put one at increased risks. 㱸㖬ぼ㸛㷻㲓㺄㽔ᱻ ⓝ㋜㽳⤈ㅠㄪ≗▙✂㗷⪹ⓞ㦆㯖⒋ⓞ㫖㺄㽔ᮣ㟗ⲿ⨍ⓞ 㫖㗁㾎㋗⍕☨㺄㽔ᮣ✂㗷⏋⺈➂㔶㵀㟗㯙⨍☨⡜ㇲᮣ Singapore Cancer Society Multi-Service Centre Fallopian tube 9 Bishan Place, Junction 8 Office Tower #06-05, Singapore 579837 6499 9133 6499 9140 ■ ■ ■ Location ☼♇ Bus Numbers ≻㖹⧟⿵ Bishan Bus Interchange 52, 53, 54, 55, 56, 57, 58, 59, 410 In front of Bishan MRT Station 13, 52, 54, 55, 58, 88, 128, 156 Along Bishan St 11 52, 54, 55, 56, 57, 58, 59, 410 Take Exit A at Bishan MRT Station. Walk through Junction 8 Shopping Centre in the direction of the Bus Interchange. Without crossing to the bus interchange at the traffic light, turn right and walk along the walkway to locate the Junction 8 Office Tower lobby. ■㟜⥙⌸㓹☾≹㷢⤖㣡㺲㨲㠭≻㖹㽊⪓㷢➝㦢㨾㽿ᮣ ■㵀⨆☪⿁ⶪ㺐㍰㱺㽊ᱨ㬄㽥㽿☤㦢㍰㽿ᱨⳟㅢ☡▕⌸㓹☾≹㷢 ⊚⤇▙⾯▙㝲ᮣ Singapore Cancer Society 15 Enggor Street, Realty Centre #04-01, Singapore 079716 6221 9578 6221 9575 www.singaporecancersociety.org.sg [email protected] Follow us on Facebook Cervix What are the Signs and Symptoms? Most of the cancer of the endometrium presents early with some form of abnormal bleeding. Majority of the cases occur in post menopausal women. ■㵀⌸㓹☼㝰㷢㽿㦢Aⓞⶪᮣ The information provided is for your general knowledge only. You should seek medical advice or treatment for your specific condition. Endometrium Endometrial Cancer Ovary Uterus Myometrium 1K102015 Ⱓ⒌⮑☨㺄㽔㑥㥲 ■ ⴊⲿ⨍ⓞ㫖 ■ 㴨ⲿ⏥⥂㵘ᱨ⽃⼋▙ ■ ⲿ㋜⭺ⓞ㫖 ■ Ⓘ㩦ⓞ㫖 ■ ➻⨆ᱨ㙦㬥⫊⊅㓧㯟☤➶⍄㣡 ■ ㈬㍻㝑㟨 ■ 㩂Ⰿ㖫㝑㟨 ■ 㝛㺺⮋㎡ What you need to know about preventing, detecting and treating Endometrial Cancer Some common symptoms are: ■ Post menopausal bleeding ■ Irregular heavy menses ■ Intermenstrual spotting ■ Prolonged spotting ■ Pink, watery or white discharge from vagina ■ Pelvic pain ■ Pain during intercourse ■ Weight loss Are You at Risk? How is Endometrial Cancer Diagnosed? ㅩ㱸➂⏋㯜㚐⿺ᱻ 㑥⧨㴊➠㽳⤈ㅠㄪ≗" Risk factors include: ■ Endometrial biopsy is done to get a sample of cells from inside the womb. ➂⏋㯜㚐⊪⸶ᱶ ■ ⌏Ⓘ⯵ⶅ㝛㺺 ■ ■ ➪㈚ ■ ⯵ⶅ㯥㖭㲓㴱⛑ Dilation and curettage is a procedure done to scrape tissue from the womb lining to be examined for cancer cells. ■ 㜽ㅸ⏋ᱨ⡽㫖㫥 ■ ⶨ㺨⧝㜽ㅸ⏋Ⰹ☱⟇㦅 ■ ╹㢦㔶㲥ᱨ㔶㲥Ⱓ㔕✛ㇲ⧧⏥㲥☨ㇲ㩂ᮣ ■ 㖳㱫〆㴨>㽳⤈ㅠ⍈㴶 ■ Obesity ■ Diabetes mellitus, hypertension ■ Women who have never given birth, women who have few children and also infertile ■ Early menarche and late menopause ■ Women with Polycystic Ovarian Syndrome ■ Irregular infrequent menses i.e. less than 4 menses per year – failure to ovulate How is it Treated? ■ ■ Ⱓ㵍ⓝⲿ⧧Ⓛ㟗ⲿᮣ Surgery is the most common treatment for this cancer, either surgical removal of the uterus alone, hysterectomy, hysterectomy with bilateral salpingo-oophorectomy or removal of the uterus, fallopian tubes and ovaries. ■ Radiation involves the use of high-dose x-rays to kill cancer cells. Ovarian tumours that secrete oestrogen e.g. Granulosa Cell tumours (Rare) ■ Hormone therapy using high dose of progestine to stop the growth of tumour. ■ Oestrogen-only Replacement Therapy (ERT) stimulates the lining of the womb and increases risk of endometrial cancer ■ ■ Women with Hereditary Non Polyposis Colorectal Cancer (HNPCC) or family history suggestive of HNPCC ■ ■ Personal history of breast or ovarian cancer have an increased risk of developing endometrial cancer ■ Female breast cancer patients who are on Tamoxifen therapy ■ ⪔㱸✂ㅘ⒚㽻⧩㺄☨ㇲ㩂ᮣ ■ 㴨ⲿ⏥㨛♛ᱨょㅰ㔕⥙4╴㴨ⲿ☨⡜ㇲḶ⏥ㅢ㈉ᮣ ■ ╬⬺㚐Ḷ㝜■⼒➈╲⬺㽳⤈ㅠㄪᱨ㵜⭩⪔㔋㽳⤈ㅠㄪ ⏋㖱ᮣ ≗☨⟇㦅ᮣ Radical Hysterectomy Fallopian tube Nearby tissue Cervix Maintain a healthy body weight ■ Healthy diet and exercise ■ Good control of diabetes can reduce the risk ■ Use of oral contraceptive pill ■ Use mirena [Medicated Intrauterine Contraceptive Device (IUCD)] Do You Know? 1 The latest Singapore Cancer Registry Annual Registry Report (2010-2014) indicates that Endometrial Cancer is the 4th most common cancer diagnosed in Singaporean women. and curettage)㮾⮂㬕㗁⟑㱸 ≗㥨⊩ᮣ 㑥⧨㺰⼒㽳⤈ㅠㄪ≗ᱻ 㔶ㅢ㺝㎐ⓥ㽳⤈⫊⯿ ⒚ᱨ㗞⤸⧧㽳⤈㐩⏩㎐ ⓥᮣ ■ ➥㔠㺰⼒㗁㮾⡽⭗⼋☨X 㔠㦏㦫ジ≗㥨⊩ᮣ How to Prevent? ■ ■ 㽳⤈ㅠㄪ⫆㾉㺑⮂␓(ⓑ㐟㽳⤈ㅠㄪ㥨⊩㬥〉)ᮣ ■ 㗐㗯㗁㾎⒋⮑☨㺰⼒➈ᮣ㮧 ■ ⟞㱫㚳㣦➲☨ㇲ㩂㑧≗⪔㸃ᮣ Ovary Uterus 㑥⧨㸓⛱㽳⤈ㅠㄪ≗" ■ ⸷㷩㽳⤈ㅠㄪ(dilatation ≗⟇㦅ᮣ ■ 㱸㑧≗⫊⒚≗⢔㑉⏋㖱☨ㇲ㩂㱸Ⱓ⡽⪔㔋㽳⤈ㅠㄪ Total Hysterectomy ■ 㖳㱫ⶪ⟞⍈㴶㮓 ■ ➶ア╬⬺㚐☨⒚㺹⽂ᮣ⺋ᱶ⧋⮑ⶕ⻯㥨⊩⽂ᮣ ■ 㱸㮯║㩂➧㥒㑠㩂▙⒎≗(HNPCC)⫊⭨㾅⪔HNPCC Chemotherapy uses drugs to kill cancer cells. ㋹(IUCD)] ■ ⬺㚐㺰⼒㖳㱫⡽⭗⼋☨㴶 ⬺㚐ᱨ㮾㾈㺛㺹⽂☨㔶⒌ᮣ Total Hysterectomy with Salpingo-oophorectomy A Hysterectomy plus Bilateral Salpingo-oophorectomy OR ■ ⪇⼒㱫㮓㣡⹂㦫ジ≗㥨⊩ᮣ B ㅩ㺌 ☤⿺" 1 ⢗⳯㨰⭩㋄≗㺄㽂␋⳨ㅰ⛪㽂␋⌔⢄(2010-2014) 㽳⤈ㅠㄪ≗㗁㨰⭩㋄⡜ㇲ☾㙼㾎⒋⮑☨≗㺄ᮣ