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Mitosis Cellular Reproduction The Cell Cycle • Your cells are always doing something, which is what is described by the cell cycle. • Sometimes, they are growing, making proteins, doing chemical reactions, and maintaining homeostasis. • Other times, they are dividing to make more cells. • These are the 2 main parts of the cell cycle. 2 parts of the Cell Cycle • During interphase, the cell grows and carries on normal cell functions. More than 95% of the time, this is what your cells are doing. • Once in while, your cells divide in half to make more cells. We call this mitosis. Mitosis: key facts • The definition of mitosis is the period of time when the cell’s nucleus divides to create 2 identical daughter cells. Mitosis: key facts • Mitosis only happens in body cells, which are called somatic cells (not reproductive cells). • Mitosis occurs in eukaryotes: plants, animals, and people. • Mitosis produces diploid cells (that have 23 pairs of chromosomes) Mitosis: Key facts • 1 cell divides in half to form 2 new cells, called daughter cells. • These cells are identical to the parent cells, and are called daughter cells. • Single celled eukaryotes can reproduce this way: asexually (all by themselves) Interphase • Interphase comes before mitosis. • During interphase, the cell makes a copy of its DNA, so that it is ready to divide. • Over 95% of the time, cells are in interphase. • Now, the cell is ready to divide in the 5 step process of mitosis! Vocabulary preparation • A duplicated chromosome looks like the letter X and each half is called a “sister chromatid.” • The sister chromatids are held together in the center by the centromere. Prophase: Phase 1 • The longest phase of mitosis. • Chromosomes come together (condense) are become visible under the microscope. • The nuclear membrane begins to dissolve. Metaphase: Phase 2 • Chromosomes line up in the center of the cell. • Centromeres attach to spindle fibers which help them move around the cell. Anaphase: rd 3 • Sister chromatids begin to pull apart at the centromere. • Sister chromatids begin to move to the opposite sides of the cell. • Chromosomes don’t look like Xs anymore, now they are chromatids. phase Telophase: Phase 4 • In telophase, the now separated chromatids reach the opposite sides of the cell. • Chromosomes start to unwind, and you can’t see them under the microscope anymore. • The nuclear membrane re-forms. Now the cell has 2 brand new nuclei, and begins to separate into 2 cells. Cytokinesis: after mitosis • Now the cell’s cytoplasm divides, so 2 new cells with 2 new nuclei are formed. • In animals, cells pinch apart along a seam called the cleavage furrow. • In plants, cells form a new cell wall in between the 2 nuclei called the cell plate. Why do cells do mitosis? • There are many reasons why cells go through mitosis: • Reproduction in single celled eukaryotes • Helps us grow bigger and taller • Helps repair wounds • Helps fetuses turn cells into tissues into organs into organ systems (development)