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1 1 Why do cells divide? • Growth and Repair • Creation of gametes 2 Chromosomes Made of densely packed DNA Human Eukaryotic Cells 1.Somatic (body) cells A.46 chromosomes b.Diploid 2.Sex cells (gametes) a.23 chromosomes b.Haploid Why would sex cells need half the number of chromosomes ? 3 Karyotype An organized profile of persons chromosomes Homologous Chromosomes --Chromosome pairs that carry genes for the SAME trait 4 5 3 Phases of The Cell Cycle G1,S, and G2 are known together as Interphase. 6 4 Interphase Body Cells Somatic cell cycle • G1 phase- Gap phase, cell undergoes growth. • S phase- DNA synthesis (replication) Sex cells are called gametes • G2 phase- Gap phase. Preparation for Mitosis. Organelles are produced. 7 11 Mitosis • Nuclear Division. • Nucleus divides once into two identical nuclei with the same DNA • YEILD: 2 diploid somatic cells 8 11 Meiosis • Nuclear Division. • Nucleus divides twice into four =nuclei with different DNA • YEILD: 4 haploid gametes 9 10 Mitosis Meiosis 1.Which type of cells go through Mitosis? 5.Which type of cells go through Meiosis? 2.The nucleus divides into how many nuclei? 6.How many times does the nucleus divide? 3.Is the DNA the same or different? 7.Is the DNA the same or different? 4.What does mitosis yield ( or 8.What does meiosis yield ( make) ? or make)? 11 Mitosis Meiosis 1.Which type of cells go through Mitosis? Somatic ( Body) 5.Which type of cells go through Meiosis? Gametes (Sex) 2.The nucleus divides into how many nuclei? 2 6.How many times does the nucleus divide? 2 3.Is the DNA the same or different? same 7.Is the DNA the same or different? different 4.What does mitosis yield ( or 8.What does meiosis yield ( make) ? or make)? 12 2 identical diploid somatic 4 different haploid gametes 12 • • • • 4 Steps of Mitosis (PMAT) Prophase: Chromosomes condense Nuclear membrane breaks down. Centrioles move to opposite sides of the cells 13 14 Metaphase: -Chromosomes attach to spindle fibers -Chromosomes line up in the middle of the cell 14 15 Anaphase: -Chromosomes separate -Chromosomes move to opposite sides of the cell 15 16 Telophase • Nuclear Envelope reforms There are now TWO nuclei in one cell! …And they contain the SAME genetic information *SAME NUMBER OF CHROMOSOMES 16 19 Cytokinesis • Cytoplasmic division • Each cell gets half of the organelles. • cell pinches in half to form two new cells. 17 21 In plant cells a cell plate forms from the inside out. • 18 18 19 23 20 25 Mitosis in Onion 21 27 22 28 23 29 Concept Map Cell Cycle includes M phase (Mitosis) Interphase is divided into G1 phase S phase is divided into G2 phase Prophase Metaphase Anaphase Telophase 24 17 25 20 Cytokinesis • Animal cells pinch. • Cytokinesis in plant cells is different from that in animal cells. 26 2 Cell Size • Why not just one large cell? • Difficult to get nutrients in and waste out 27 5 G1 Phase •Cell grows 28 6 S Phase • Chromosomes Condense • Chromosomes are inherited genetic information • Chromosomes are made up of DNA • Can only be seen when cells are dividing 29 7 S Phase • Chromosomes replicate-or copy is made • The two copies are • -attached together at a point called a centromere. • -are called sister chromatid. 30 8 31 9 G2 Phase Organelles must be replicated (copied) 9 32 10 M Phase Two parts: 1.Nuclear division – Mitosis 2.Cytoplasmic Division – Cytokinesis 10 33 22 Mitosis review video clip with quiz! 34 24 Results of Mitosis and Cytokinesis • Two new cells. • The new cells- called daughter cells- have the same number of chromosomes as the mother cell. • This occurs in all somatic cells in your body. • You have 46 chromosomes in all of your somatic cells-23 pair! 35 26 Cells during Mitosis 36 30 Reproduction of Sex Cells • Sex cells- Sperm and egg • Process is called Meiosis • Similar to Mitosis 37 31 Meiosis • Cell divides twice • First division is like mitosis and then the cell divides again to create 4 haploid cells. 38 32 MEIOSIS=CHROMOSOME REDUCTION DIVISION 39 33 40 34 Meiosis • Meiosis is also know as chromosome reduction division. • Start with 46 and ends up with 23. • Why? • Fertilization creates the diploid condition again Haploid Diploid 41 35 • Sperm formation- 4 haploid sperm cells are formed. • Egg formation-most of the cytoplasm is used in one cell and the other three disintegrate. One haploid egg cell is formed. 42 36 Meiosis Video Clip 43 37 Crossing Over • Sometime during meiosis the chromosomes can exchange information • This is called Crossing Over • Major source of genetic diversity in the species 44 38 45 39 Prokaryotic Cells • Binary fission • Occurs in Prokaryotic Cells • DNA is copied and then the cell splits in half. 46 40 Regulation of the Cell Cycle • How do cells know when to divide? When to stop dividing? • Cyclins-proteins that regulate the cell cycle. 47 41 Cancer • Unregulated cell growth. • Can form masses of cells called tumors. 48