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Reproduction & Cell Cycle QuickTime™ and a decompressor are needed to see this picture. Homework Objectives • Be able to explain how/why mitosis produces identical cells • Know the four stages of mitosis, plus cytokinesis • Be able to draw and recognize a picture of each stage • Be able to explain the major event that happens in each stage • Be able to say what order they happen in Mitosis Movies • http://www.cellsalive.com/mitosis.htm http://www.johnkyrk.com/mitosis.html http://youtube.com/watch?v=0oJZDKdperU&feature= related http://youtube.com/watch?v=rgLJrvoX_qo&feature=re lated http://highered.mcgrawhill.com/sites/0072495855/student_view0/chapter2/a nimation__mitosis_and_cytokinesis.html Cell Cycle Model • To help you learn, you will: • Make a moving model of the cell • Draw a picture of what it looks like in each stage • Write the important thing that happens in each stage • Remember: your real goal is to be able to say why mitosis produces identical cells… Cell Cycle Model • Each group gets one baggie. Do not eat your candy, it’s gross and you need it to make your cell. • (I’ll give you uncontaminated candy at the end, if you earn it!) • Clear off your table. Keep out the two handouts and something to write with. • Do not open the baggie, follow my instructions! Cell Cycle Model • Long piece of string = cell membrane. • Small piece of string = nuclear membrane or nuclear envelope. Cell Cycle Model • Gum Drops = centrioles. Put THREE of them in the cell cytoplasm. Cell Cycle Model • Worms/Good n Plenties = chromosomes. • Each kind of candy (gummi worm, sour worm, good n’ plenty) is one chromosome number. • Two candies of the same color = homologous chromosomes. • Put ONE of each homologous chromosome in the nucleus. Cell Cycle Model: Interphase • We begin in interphase. Interphase in a cell is different than this model; the chromosomes are unwound enough that you can’t see each one. • When the cell needs to divide, it starts by replicating its DNA in S phase. • Replicate your chromosomes. Each homologous chromosome is now made of two sister chromatids. Cross them over at the middle. This point, where the sister chromatids connect, is called the centromere. • It also replicates its centrioles. Cell Cycle Model: Interphase • Human chromosomes ready for mitosis. • Same as the image before, but now each homologous chromosome is made of two identical sister chromatids joined at the centromere. Cell Cycle: Interphase • So, interphase: Normal metabolism. Replicates DNA in S phase, turning each chromosome into two sister chromatids. Cell Cycle Model: Mitosis • Prophase • Chromosomes condense and are visible. • (Our model is weird like this.) • Centrioles separate. • Spindes begin to form between the centrioles. • Nuclear envelope begins to break down. Cell Cycle Model: Mitosis • Metaphase: • Chromosomes line up across the center of the cell. • Each centromere is connected to a spindle. Cell Cycle Model: Mitosis • Anaphase: • Sister chromatids separate. • Spindles pull each chromatid towards one side of the cell. • For each chromosome, one chromatid is pulled to one side, and the other chromatid is pulled to the other side. Cell Cycle Model: Mitosis • Telophase: • The chromosomes are pulled to opposite ends of the cell. • Spindles let go of their centromeres. • Two new nuclear envelopes form. Cell Cycle Model: Cytokinesis • Cytokinesis: • The cytoplasm and organelles copy and move away from the middle of the cell. (not modeled) • The cell membrane moves in towards the center and the cell pinches in half. • The end result is two smaller but identical cells, called daughter cells. Cell Cycle • If a cell with 32 chromosomes (16 different kinds of chromosome) goes through mitosis, how many chromosomes will each of its daughter cells have? • If a diploid cell goes through mitosis, will its daughter cells be diploid or haploid? IPMATC • Interphase • G1, S, G2 • Mitosis • • • • Prophase Metaphase Anaphase Telophase • Cytokinesis • It can take as little as ten minutes or as long as 2 hours for a cell to divide. • Some cells divide almost daily, others never do. Cell Cycle Model • Reset your candy cell to how it was at the beginning. • Repeat what we just did. As you go through, say out loud what stage you’re modeling. As you manipulate some part or another, say its name. • Work as a team, I’m trusting you with the task of making sure that both you AND everybody at your table gets this. Latin/Greek Word Parts • (Homo • “Same”) • Inter • “Between” • Centr • “Middle, central” • (Pro • “Forward”) • Meta • “After” • Ana • “Upward, across, away, apart” • Tel • “End, far” For the rest of the block: • Go through the candy cell cycle some more times if you aren’t confident that you know the steps. • Complete your vocabulary sheet, working with others is encouraged. Use a textbook if you’d like. • Before your leave, put everything back in your bag, and get a fresh candy!