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1 1 2 Cell Size • Why not just one large cell? • Difficult to get nutrients in and waste out 2 3 Phases of The Cell Cycle G1,S, and G2 are known together as Interphase. 3 4 Interphase Regular Cells Somatic cell cycle • G1 phase- Gap phase, cell undergoes growth. • S phase- DNA synthesis Sex cells are called gametes • G2 phase- Gap phase. Preparation for Mitosis. Organelles are produced. • M phase- Cell division (Mitosis and cytokinesis) 4 5 G1 Phase •Cell grows 5 6 S Phase • Chromosomes Condense • Chromosomes are inherited genetic information • Chromosomes are made up of DNA • Can only be seen when cells are dividing 6 7 S Phase • Chromosomes replicate-or copy is made • The two copies are • -attached together at a point called a centromere. • -are called sister chromatid. 7 8 8 9 G2 Phase Organelles must be replicated (copied) 9 9 10 M Phase Two parts: 1.Nuclear division – Mitosis 2.Cytoplasmic Division – Cytokinesis 10 10 11 Mitosis • Nuclear Division. • Nucleus divides into two new nuclei Mitosis keeps the number of chromosomes constant from one cell generation to the next. • In eukaryotes, it is the main process by which growth and tissue repair is accomplished. • Mitosis is also the main process by which single-celled and many multi-celled 11 eukaryotes reproduce asexually. 12 4 Steps of Mitosis (PMAT) • Prophase: Chromosomes condense and attach to the spindle fibers at their centromere. • Nuclear Membrane breaks down. 12 13 Steps of Mitosis (PMAT) • Prophase: Centrioles move to opposite sides of the cell and organize the spindle fibers 13 14 Metaphase: Chromosomes attach to spindle fibers and line up in the middle of the cell 14 15 Anaphase: Chromosomes separateMove to opposite sides of the cell 15 16 Telophase • Nuclear Envelope reforms There are now TWO nuclei in one cell! …And they contain the SAME genetic information*SA ME NUMBER OF CHROMOSOMES 16 17 17 18 18 19 Cytokinesis • Cytoplasmic division • Each cell gets half of the organelles. • After mitosis: cell pinches in half to form two new cells. 19 20 Cytokinesis • Animal cells pinch. • Cytokinesis in plant cells is different from that in animal cells. 20 21 In plant cells a cell plate forms from the inside out. • 21 22 Mitosis review video clip with quiz! 22 23 23 24 Results of Mitosis and Cytokinesis • Two new cells. • The new cells- called daughter cells- have the same number of chromosomes as the mother cell. • This occurs in all somatic cells in your body. • You have 46 chromosomes in all of your somatic cells-23 pair! 24 25 Mitosis in Onion 25 26 Cells during Mitosis 26 27 27 28 28 29 Concept Map Cell Cycle includes M phase (Mitosis) Interphase is divided into G1 phase S phase is divided into G2 phase Prophase Metaphase Anaphase Telophase 29 30 Reproduction of Sex Cells • Sex cells- Sperm and egg • Process is called Meiosis • Similar to Mitosis 30 31 Meiosis • Cell divides twice • First division is like mitosis and then the cell divides again to create 4 haploid cells. 31 32 MEIOSIS=CHROMOSOME REDUCTION DIVISION 32 33 33 34 Meiosis • Meiosis is also know as chromosome reduction division. • Start with 46 and ends up with 23. • Why? • Fertilization creates the diploid condition again Haploid Diploid 34 35 • Sperm formation- 4 haploid sperm cells are formed. • Egg formation-most of the cytoplasm is used in one cell and the other three disintegrate. One haploid egg cell is formed. 35 36 Meiosis Video Clip 36 37 Crossing Over • Sometime during meiosis the chromosomes can exchange information • This is called Crossing Over • Major source of genetic diversity in the species 37 38 38 39 Prokaryotic Cells • Binary fission • Occurs in Prokaryotic Cells • DNA is copied and then the cell splits in half. 39 40 Regulation of the Cell Cycle • How do cells know when to divide? When to stop dividing? • Cyclins-proteins that regulate the cell cycle. 40 41 Cancer • Unregulated cell growth. • Can form masses of cells called tumors. 41