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Cell Reproduction The Cell cycle: • Just as you have a distinct life cycle, so do cells. • You spend most of your life growing and maturing, and only a small portion of your life reproducing. • The same is true for cells. Why are more cells needed? • • • • Growth Repair after injury Replacement of worn out cells In simple organisms a form of cell division is used for reproduction! • Grrr..... 3 Cell Cycle 4 • http://www.bdbiosciences.com/research/apoptosis/analysis/index.jsp INTERPHASE • Phase between cell division... G1...S...G2 • Cell grows and does its job • DNA is uncoiled and invisible (chromatin) • DNA copied during S The process of cell division includes two parts: • Mitosis - comes first to copy the nucleus then Cytokinesis will divide the cytoplasm and organelles to form two daughter cells • “I hit my toe sis!” • Mitosis consists of many different stages The most important part : • Mitosis makes sure the nucleus is copied exactly! Making sure the right number chromosomes end up in both cells. • You have 46 chromosomes in every cell • Thus each cell must make a copy of each chromosome before it divides Mitosis Stage 1: PROPHASE • nuclear membrane breaks down • Chromatin wind to become visible chromatids • chromatids (pairs of chromosomes) stay attached by a centromere. • Centrioles (poles) appear and move to opposite sides of cell • Spindle fibers form between poles Chromatids • Two identical chromosomes joined at a centromere CHROMOSOME CENTROMERE SISTER COPY Stage 2: Metaphase • Chromotids attach to spindle fibers • Chromotids line up on midline (equator) of cell (meet in middle) Stage 3: Anaphase • Chromatids separate and move to opposite ends of the cell • Centromere splits in half Stage 4: Telophase • Spindle disappears • Chromosomes unwind and become less visible • Nuclear membranes form around the new sets of chromosomes • Cell begins to pinch into two • Mitosis ends with 2 nuclei in a single cell Cytokinesis • The division of the rest of the cell: cytoplasm and organelles - roughly in half • Two daughter cells are formed when this is complete Cytokinesis Cytokinesis = Division of the cytoplasm and the organelles In animal cells, the cytoplasm “pinches in” until the 2 new cells have formed © 2006 STCC Foundation Press, content by Dawn A. Tamarkin, Ph.D. 14 Cytokinesis in Plant Cells Since the cell wall will not allow “pinching inward” a cell plate grows from the middle of the cell to the outside. After the cell plate is complete, the cell walls are build around it. 15 © 2006 STCC Foundation Press, content by Dawn A. Tamarkin, Ph.D. How to remember the order: Text