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Homeostasis & Cell Transport • Passive Transport – Diffusion aka Simple Diffusion – Osmosis – Facilitate Diffusion • *No energy required • Active Transport – Cell Membrane Pumps – Endocytosis and Exocytosis • *Requires energy Passive transport is diffusion across a membrane • What is diffusion or simple diffusion? – Movement of molecules from an area of HIGH concentration to LOW concentration. – Driven entirely by kinetic energy the molecules possess. Molecules are in constant motion. • Think about when you open a bottle of perfume…The bottle has a high concentration of perfume the air has a _____ concentration. So the molecules in the perfume want to go??? • A simple rule of diffusion: a substance will diffuse from where it is more concentrated to where it is less concentrated. To put it another way, any substance will diffuse down its concentration gradient. More Diffusion… • When does diffusion stop? – When the concentration of the molecules of a substance is the same throughout a space called? • What types of molecules can move into a cell by diffusion? – Oxygen and carbon dioxide because they dissolve in lipids. More Diffusion… • Is diffusion regulated? – Is the cell membrane selective? – What kind of molecules are going to diffuse across a cell membrane? • Size and type of the molecule…the smaller the better! • Chemical nature of the membrane…if they dissolve in lipids! Osmosis is the passive transport of water • What is osmosis? – The process by which water molecules diffuse across a cell membrane from an area of higher concentration to an area of lower concentration. • How does osmosis affect a cell? – Under HYPERTONIC conditions? – H2O out – Under HYPOTONIC conditions? – H2O in – Under ISOTONIC conditions? – H2O same • Remember…where salt goes water will follow!!! More osmosis… • How do cells deal with osmosis? – Vertebrate animals living on land and most living in the sea…cells function in an isotonic external environment – NO PROBLEM when balancing movement of water. – Unicellular freshwater organisms…cells function in hypotonic environments – Water CONSTANTLY diffuses into these organisms. • How do they get rid of this excess water that enters by osmosis? – Contractile Vacuole More osmosis… – How do plant cells deal with osmosis? Remember they live in hypotonic environments… • Turgor pressure – if pressure against the cell walls is so great…water will be pushed out of the cell. – In a hypertonic environment…water leaves plant cells by osmosis. • The cells shrink away from the cell walls and turgor pressure is lost…this is called plasmolysis. – Changes to a cell’s environment can create problems…Human Red Bloods Cells • Cytolysis – hypotonic environment…cells burst!!! Facilitated Diffusion • What is facilitated diffusion? • How is this different from simple diffusion? – How does the selectivity compare? • MORE selective than simple diffusion…molecules are assisted by specific proteins in the membrane. • What are carrier proteins? • Example…How does glucose, a molecule that many cells need for their energy, get into the cell? • Must diffuse down its concentration gradient!!! What did we learn? • Diffusion is SLOOOOOOWWWW!!! • Osmosis is the diffusion of water. • Hypertonic, hypotonic, isotonic (remember where salt goes water will follow). • Facilitated diffusion uses carrier proteins to help large molecules across the cell membrane. Active Transport • What is active transport? • How is it different than passive transport? – Where does the energy come from to drive active transport? • What are cell membrane pumps? • What kind of proteins do they use? • An example of a cell membrane pump… – Sodium-Potassium pump…the mother of all pumps – How does the Sodium-Potassium Pump work? • Exchanges sodium (Na+) for potassium (K+) across the cell membrane of animal cells. Other types of active transport… • What is Endocytosis? – What are the two types of endocytosis? – What does pinocytosis involve? – What does phagocytosis involve? • What is Exocytosis? What did we learn today? • Active transport uses ATP (it’s energy currency) to move molecules from low to high concentration. • Cell membrane pumps ex. SodiumPotassium Pump. • Endocytosis and Exocytosis