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Clinical computing and the repository George Hripcsak Jim Cimino Pete Stetson WebCIS Data sources MED Info resources Repository CDW Data mart George Hripcsak • MD – internal medicine • MS – biostatistics • Professor and Vice Chair Repository • 13 years • > 2,000,000 patients • > 5,000,000 narrative reports • Data are useful only for the purpose for which they were collected • Data collected without a purpose are useless • We are overflowing with information • We just need to know how to tap it Data mining • We can use the information in the repository to discover knowledge about medicine and biology • So close and yet so far Range of projects Theoretical Practical (Use of natural language processing) • Carol Friedman, Steve Johnson Temporal representation and reasoning 2003-09-06-08:11:34.243563 My pneumonia was a while before the stroke Case-based reasoning • Match on a case level (gestalt) to overcome inaccuracies and missing data Evaluation • Use computer intensive techniques to figure out whether you have a significant data mining result Summarization • Give providers a quick summary of the important facts about a patient Patient safety • Detect (and someday prevent) medical errors using the repository Jim Cimino • MD – internal medicine • Postdoctoral fellowship (MGH) • Professor Data Re-View and Re-Use • View: look at data in their original form • Re-View: alternate views of clinical info • Use: original intent for collecting data • Re-Use: any other use Data Re-View • For other users: PatCIS Data Re-View • For other users: PatCIS • For other platforms: PalmCIS Data Re-View • For other users: PatCIS • For other platforms: PalmCIS • Problem-oriented views: QingCIS Data Re-View • For other users: PatCIS • For other platforms: PalmCIS • Problem-oriented views: QingCIS • Using patient data to improve information retrieval: MendonCIS Data Re-View • For other users: PatCIS • For other platforms: PalmCIS • Problem-oriented views: QingCIS • Using patient data to improve information retrieval: MendonCIS Data Re-Use • Examples of reuse: – Summary reports – Automated decision support – Context-specific information retrieval (infobuttons) • Challenge: – Mapping concepts of raw data to concepts of reuse • Solution: – Medical Entities Dictionary MED Structure Medical Entity Substance Chemical Laboratory Specimen Anatomic Substance Plasma Carbohydrate Bioactive Substance Glucose Plasma Specimen Event Diagnostic Procedure Laboratory Test Plasma Glucose Test Laboratory Procedure CHEM-7 Part of Translations with the MED Intravascular Gentamicin Tests Summary Reports Injectable Gentamicin Serum Gentamicin Level Gentamicin Gentamicn Sensitivity Test Decision Rule Gentamicin Toxicity Drug Information Expert System Research Issues • Identifying information needs • Developing automated solutions • Conceptual mapping • Terminology management Pete Stetson • Training: – MD – Internal Medicine – MA – Informatics (Columbia’s RMA) • Positions: – Assistant Professor – Associate Program Director, IM Residency – Chair, Institutional Decision Support and Clinical Alerts Committee Projects “Real solutions for real users.” Patient Safety: – Detection: • Computerized algorithms to screen the electronic medical record for adverse events (CLIPS) – Prevention: • Clinical Alerts • Information Access – PalmCIS • Clinical Communication – – – – Understanding how physicians talk to eachother (Sign-outs) Increasing the portability of patient information (PalmCIS) Matching patients to providers (Patient-Provider Index) Improving capture of narrative data (Hospitalist eNote) Potential Student Projects • Detection: – Using NLP to screen narrative data for evidence of adverse events • Prevention: – Development and ownership of alerts (eg: K+ > 6.0) – User interface design for new PalmCIS platforms – Development of an algorithm to match patients to their primary providers (PPI) – User interface design, evaluation, real-time NLP, summarization views of clinical notes (Hospitalist eNote) Hospitalist eNote Architecture WebCIS User MD Input CDR CDW Billing Office MD Review Billing Compliance Officer To IDX