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SC 131 Unit 5 Digestive System EMILY BRADSHAW, PH.D. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Agenda Anatomy of the digestive system Process of digestion Benefits of dietary fiber Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings The Digestive System and Body Metabolism Digestion Breakdown of ingested food Absorption of nutrients into the blood Metabolism Production of cellular energy (ATP) Constructive and degradative cellular activities Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Processes of the Digestive System Ingestion Mechanical Digestion Chemical Digestion Enzymes break down food Carbohydrates are broken to simple sugars Proteins are broken to amino acids Fats are broken to fatty acids and alcohols Absorption Defecation Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Mouth (Oral Cavity) Anatomy Mastication (chewing) of food Mixing masticated food with saliva Initiation of swallowing by the tongue Allowing for the sense of taste Figure 14.2a Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Pharynx Function Serves as a passageway for air and food Food is propelled to the esophagus by two muscle layers Longitudinal inner layer Circular outer layer Food movement is by alternating contractions of the muscle layers (peristalsis) Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Esophagus Runs from pharynx to stomach through the diaphragm Conducts food by peristalsis (slow rhythmic squeezing) Passageway for food only (respiratory system branches off after the pharynx) Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Stomach Functions Acts as a storage tank for food Site of food breakdown Chemical breakdown of protein begins Delivers chyme (processed food) to the small intestine Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Structure of the Stomach Mucosa Gastric pits formed by folded mucosa Presence of food or falling pH causes the release of gastrin Gastrin causes stomach glands to produce proteindigesting enzymes Hydrocholoric acid makes the stomach contents very acidic Activates pepsinogen to pepsin for protein digestion Provides a hostile environment for microorganisms Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Chemical Digestion in the Small Intestine Source of enzymes that are mixed with chyme Intestinal cells Pancreas Bile enters from the gall bladder Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Villi of the Small Intestine Fingerlike structures formed by the mucosa Give the small intestine more surface area Absorptive cells Blood capillaries Lacteals – absorb fat Figure 14.7a Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Stimulation of the Release of Pancreatic Juice Vagus nerve Local hormones Secretin Cholecystokinin Pancreatic enzymes play the major digestive function Lipase Nucleases Alkaline Figure 14.16 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Absorption in the Small Intestine Water is absorbed along the length of the small intestine End products of digestion Most substances are absorbed by active transport through cell membranes Lipids are absorbed by diffusion Substances are transported to the liver by the hepatic portal vein or lymph Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Large Intestine Larger in diameter, but shorter than the small intestine Does NOT participate in digestion of food; ONLY absorption of water Eliminates indigestible food from the body as feces Goblet cells produce mucus to act as a lubricant Resident bacteria digest remaining nutrients Produce some vitamin K and B Release gases Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Liver Largest gland in the body Consists of four lobes suspended from the diaphragm and abdominal wall Connected to the gall bladder via the common hepatic duct Bile - produced by cells in the liver Composition: bile salts, bile pigment (mostly bilirubin from the breakdown of hemoglobin), cholesterol, phospholipids, electrolytes Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Gall Bladder Sac found in hollow fossa of liver Stores bile from the liver by way of the cystic duct Bile is introduced into the duodenum in the presence of fatty food Gallstones can cause blockages Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Dietary Fiber Includes all parts of plant foods that your body can't digest or absorb. Fiber is commonly classified into two categories: those that don't dissolve in water (insoluble fiber) and those that do (soluble fiber). Insoluble fiber: Promotes the movement of material through your digestive system and increases stool bulk. Examples: Whole-wheat flour, wheat bran, nuts and many Soluble fiber: Dissolves in water to form a gel-like material. It can help lower blood cholesterol and glucose levels. Examples: Oats, peas, beans, apples, citrus fruits, carrots, and barley Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Image credit: www.pharmage.com Benefits of Dietary Fiber Normalizes bowel movements. Dietary fiber increases the weight and size of your stool and softens it. A bulky stool is easier to pass, decreasing your chance of constipation. Helps maintain bowel integrity and health. A high-fiber diet may lower your risk of developing hemorrhoids, and small pouches in your colon (diverticular disease). Lowers blood cholesterol levels. Soluble fiber found in beans, oats, flaxseed and oat bran may help lower total blood cholesterol levels by lowering low-density lipoprotein, or "bad," cholesterol levels. Helps control blood sugar levels. Fiber, particularly soluble fiber, can slow the absorption of sugar, which for people with diabetes can help improve blood sugar levels. Aids in weight loss. High-fiber foods generally require more chewing time, which gives your body time to register when you're no longer hungry, so you're less likely to overeat. Also, a high-fiber diet tends to make a meal feel larger and linger longer, so you stay full for a greater amount of time. And high-fiber diets also tend to be less "energy dense," which means they have fewer calories for the same volume of food. Uncertain effect on colorectal cancer. Evidence that dietary fiber reduces colorectal cancer is mixed — some studies show benefit, some show nothing and some suggest increased risk. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Sources of dietary fiber Grains and whole-grain products Fruits Image credit: www.fiberchoice.com Vegetables Beans, peas and other legumes Nuts and seeds Refined or processed foods — such as canned fruits and vegetables and pulp-free juice, white bread and pasta, and non-whole-grain cereals — are lower in fiber content. Whole foods rather than fiber supplements are generally better. Fiber supplements — such as Metamucil, Citrucel and FiberCon — don't provide the vitamins, minerals and other beneficial nutrients that high-fiber foods do. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Questions???? Image Credit: Microsoft Clip Art Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings