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Biology 20 Digestive System 2 DIGESTIVE SYSTEM HETEROTROPHIC NUTRITION Unable to manufacture food from inorganic molecules. Depend on autotrophs. AUTOTROPHIC NUTRITION Organisms capable of synthesizing organic molecules from simple inorganic material. Types: photosynthesizers and chemosynthesizers. 3 4 Steps of Heterotrophic Nutrition 1) Ingestion • eating or drinking • Heterotrophs need: – Sugars – Amino Acids – Fatty Acids – Glycerol – Minerals – Vitamins 4 4 Steps of Heterotrophic Nutrition 2) Digestion • Breakdown of macromolecules into smaller ones that can be absorbed by the cells – Mechanical -- chewing – Chemical -- digestive enzymes 5 4 Steps of Heterotrophic Nutrition 3) Absorption • Nutrients are absorbed into the blood – Digested monomers – Water – Minerals – Vitamins 4) Egestion • Elimination of undigested material 6 Parts Organs • • • • • • • Mouth Pharynx Esophagus Stomach Small Intestine Large Intestine Rectum Glands • • • • Salivary Glands Pancreas Liver Gall Bladder 7 Order of Events Order of Events Digestive System •Overview – Labeling of the Digestive system! 10 Digestive System 11 Mouth Hard Palate • hard part of roof of mouth Soft Palate • back of roof of mouth Pharynx • chamber in throat where – nasal cavity and mouth meet – esophagus and trachea meet Mucus Membranes • lubricates walls of mouth for easy passage of food 12 Mouth Purpose • Mechanical digestion by teeth and tongue – increases surface area for action by enzymes – Mixes food thoroughly • Chemical digestion by enzymes in saliva Secretions • Saliva – 1 to 2 liters per day – from 3 pairs of glands in the mouth 13 Salivary Glands 14 Mouth Composition of Saliva • Water – moistens food • Amylase – begins STARCH digestion • Mucin – lubricant – binds food together for easier swallow 15 Mouth Control of Salivary Secretions • Mechanical pressure – food in the mouth • Nervous system – Brain thinking of food in the mouth – Signal sent to salivary glands from the brain – Mmmmmmm. Fooooood…. 16 Order of Events Pharynx 18 Pharynx 19 Pharynx Throat Common tube through which both air and food pass Four openings • Nasal Cavity • Trachea Mouth Cavity Esophagus Contains a flap of tissue called the EPIGLOTTIS • This prevents food from entering the trachea 20 Order of Events Esophagus Hollow muscular tube Connects pharynx to the stomach What makes the food go to the stomach? Movement of food by peristalsis • rhythmic waves of contraction and relaxation of muscular walls • food is squeezed through esophagus into stomach 22 Peristalsis 27 Peristalsis 28 Esophagus Hollow muscular tube Connects pharynx to the stomach What makes the food go to the stomach? Movement of food by peristalsis • rhythmic waves of contraction and relaxation of muscular walls • food is squeezed through esophagus into stomach Epiglottis shunt food into esophagus during swallowing 29 Esophagus Structure • thick walled and muscular • from pharynx to stomach • walls contain mucus glands which secrete mucin – mucin lubricates food for easy passage 30 Order of Events Stomach a hollow muscular pouch located high in the abdominal cavity, just under the diaphragm The esophagus connects to the stomach by the cardiac sphincter. Heartburn • muscular ring surround esophagus at this point • acts like a valve to open and close the tube • keeps the food from falling out of your stomach when standing on your head. 32 Stomach 33 Stomach FUNCTIONS • temporary storage of food • liquefaction of food • beginning of protein digestion 36 Secretions -- Gastric Juice Secreted into the stomach cavity by stomach cells • churning of the stomach mixes juice with food Contains • Hydrochloric Acid – HCl(aq) – pH of 1-2 – destroys bacteria present in food – liquefies food. 37 Secretions -- Gastric Juice • Pepsin –an enzyme which begins protein digestion • (proteins broken down into smaller chains) But aren’t the stomach cells made of protein? –Pepsin is produced and secreted in an inactive form called pepsinogen • which is converted into the active form by the low pH. • This protects the cell from self-digestion 38 Stomach stomach lined with mucus coating • prevents acid and protein digesting enzymes from damaging wall when food is liquefied it is called chyme. squirted into small intestine through the pyloric sphincter 39 Stomach 40 Small Intestine About 6 meters long • Three sections 1) Duodenum • first 25 cm • digestion 2) Jejunum • next 2 meters • absorption 3) Ileum • next 4 or 5 meters • absorption 41 Small Intestine FUNCTION • complete the digestion of food • absorb the nutrients into the circulatory system (blood) • important secretions from the pancreas and the liver. 43 Secretions -- Pancreatic Fluid Contains • NaHCO3 – sodium bicarbonate – raises pH to 8 • Pancreatic Amylase – an enzyme which continues the digestion of starch into maltose units • Lipase – enzyme digesting lipids into fatty acids & glycerol • Trypsin and Chymotrypsin – enzymes which continue protein digestion – also secreted in inactive forms – activated by alkaline pH 44 Small Intestine LIVER and GALLBLADDER • The liver produces bile – brown fluid • bile is stored in the gallbladder • when fats enter the small intestine, the gallbladder contracts and squirts bile into the duodenum 45 Small Intestine • bile emulsifies fats –physically breaks them down into smaller drops –Kaboom!!! Blows it up!!! –greater surface area for action by lipase • bile is NOT an enzyme because it does not cause a chemical change in fat. 46 Small Intestine All types of foods are acted upon. 47 Small Intestine digestion of disaccharides and dipeptides is completed by enzymes produced by the small intestine • sucrase – digests sucrose • maltase – digests maltose • lactase – digests lactose • aminopeptidase – breaks down dipeptides into amino acids 48 Small Intestine once all food molecules are at monomer stage, they are ready to be absorbed into the circulatory system the inside of the S.I. is covered with millions of tiny finger-like projections called villi • each villus is actually covered with millions of microvilli • the villi and microvilli increase surface area for absorbing food molecules into blood. 49 Absorption in the Small Intestine Digested Nutrient Product Method of Absorption Site of Absorption Small Intestine notice that glycerol recombines with 3 fatty acids to form a fat molecule which enters the lacteal instead of the capillary Why is fat completely digested and then recombined to form a fat molecule again? 55 Large Intestine 56 Large Intestine Material NOT absorbed by this point will enter the large intestine through another sphincter – the ileal-caecal sphincter The caecum is a small pouch at the beginning of the large intestine. • contains a small projection called the appendix – this is a vestigial organ which functions in cellulose digestion in some herbivorous mammals 58 Functions of the Large Intestine absorb water into blood absorb vitamins and minerals into blood eliminate undigested material from digestive tract 59 Large Intestine Some bacteria live in the large intestine of mammals • they digest material that we are not able to digest a byproduct of this activity results in the synthesis of vitamins • Vitamin K 60 61 Rectum & Anus Rectum & Anus last section of digestive tract rectum is a holding pouch for feces feces exits the digestive tract through a sphincter muscle called the anus. rectal veins are found near opening • if they get inflamed… – the inside diameter of anus decreases – passage of feces is difficult and painful – called hemorrhoids or piles. 63 What About Fiber??? fiber in the diet serves to retain water throughout the digestive tract resulting in soft feces. 66 1 = Esophagus 2 = Stomach 3 = Small Intestine 4 = Pancreas 5 = Liver 6 = Large Intestine 7 =Large Intestine 8 =Large Intestine 9 = Large Intestine 10 = Rectum Biology 20 Control of Digestive Secretions Saliva Nervous • Pavlov • Sight, smell, presence, or even thought of food stimulates vagus nerve • results in the production of saliva 69 Gastric Juice Nervous • Stimulation of vagus nerve also stimulates cells of stomach to begin producing gastrin 70 Gastric Juice Hormonal • Gastrin (a hormone) is released from certain upper stomach cells into the bloodstream. • gastrin circulates until it reaches the lower stomach cells resulting in the release of gastric juices. • Once pH falls below 2, gastrin stops being secreted. • If pH rises above 2.5 gastrin secretion begins again. 71 Pancreatic Juice Nervous • presence of food in mouth and stomach stimulates pancreatic secretions Hormonal • presence of chyme in the S.I. causes the cells of the duodenum to secrete the hormone secretin into the blood • Secretin (a hormone) causes the pancreas to begin producing pancreatic juice • Pancreatic Juice will enter the duodenum through the pancreatic duct. • when acidic chyme becomes alkaline, production of secretin stops 72 Liver & Gall Bladder 73 Bile Hormonal • presence of chyme in the S.I. causes the cells of the duodenum to secrete the hormone cholesystekinin into the blood. • This causes the gall bladder to contract, propelling bile into the duodenum through the bile duct 74 Biology 20 FUNCTIONS OF THE LIVER Liver largest organ in the body receives blood from 2 supplies • hepatic artery – oxygen rich blood from heart • hepatic portal vein – nutrient rich blood from intestinal walls liver acts as a “gatekeeper” between blood leaving intestines and blood entering general circulation • the liver removes excess nutrients 76 Liver & Gall Bladder 77 Functions of the Liver 1) Digestive Function • Production of bile which emulsifies fats 2) Regulation of Blood Glucose • removes excess glucose from blood after meal and converts it to glycogen • once glycogen stores are full, it converts extra glucose into fat which is released from liver into the blood and stored in adipose tissue • when blood sugar levels fall, liver converts glycogen back into glucose and releases it into blood 78 Functions of the Liver 3) Breakdown of Red Blood Cells • destroys old RBC’s • the pigment is excreted in bile • the iron is stored for future RBC’s 4) Synthesis of Plasma Proteins • manufactures important blood proteins – fibrinogen – albumin – globulin 79 Functions of the Liver Storage • vitamin B12 • fat-soluble vitamins • iron Detoxification • liver breaks down poisons and non-food substances in blood • e.g.: alcohol, caffeine, nicotine, drugs, excess hormones Excretory Function • deamination (breakdown) of excess amino acids • production of urea – excreted in urine 80