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Clinical Decisions Management of Skin and Soft-Tissue Infection Treatment Option 1 Comments Treatment Option 2 Comments Treatment Option 3 Comments Treatment Option 1: Incision and drainage alone. 132 Readersʼ Comments Kingston Okrah | Physician | Disclosure: None University of Iowa | Coralville, Iowa USA September 20, 2008 Patient is young and immunocompetent, at the moment he has no indication of disseminated infection and no organism has been isolated from the abcess yet to direct antibiotic choice. Most cutaneous infections are well treated with just I & D and even though he is at risk of exposure to MRSA from his involvement in contact sport, I will not start systemic antibiotics until I have evidence of systemic involvement. Sausan Campbell MD | Physician | Disclosure: None BellSouth.net | Asheville, North Carolina USA September 20, 2008 There is overuse of antibiotics in our medical culture today- largely due to fear rather than valid culture results and in some cases even if wound cultures are negative most physicians still overtreat. Less is better in this scenario where we are dealing with a healthy active young male who has the common occasional abscess due to increased sweat production and exposure to different showers in various places across the country. His exam is only remarkable for skin involvement without any evidence of systemic disease. Given the growing number of highly resistant organisms, we would be doing a disservice to this young male by altering his own "flora" and predisposing him to developing a resistant strain in the future. Junko Okamoto | Physician | Disclosure: None Kinki University | Osaka-sayama, Japan September 25, 2008 As the infection is supposed to be localized, systemic anitibiotics seems to be over-indication. I'd add some ointment as local antibiotics. Culture is neccesary, of course. Rusty Ellis Human | Other | Disclosure: None Comcast Cable | Los Gatos, California USA September 25, 2008 less is more in this case. Begin with less and observe sucess. Additional treatment can be added but not taken away. N Dua | Physician | Disclosure: None Columbia University | New York, New York USA September 25, 2008 Many hospital guidelines would recommend I&D alone in this case. Most of the current literature consists of retrospective reviews with large variability in inclusion criteria as well as treatment outcomes studied. Interestingly, Dr. Chambers and Dr.Kamitsuka cite the same article to support their different decision making (Ruhe et al,clin.inf.dis.2007,44:777-84)Though the authors note a statistically significant impact with active antibiotic use, they recommend limiting antibiotic therapy to patients with a suboptimal response or significant co-morbidities Christopher Ward MD | Physician | Disclosure: None Frontier Communications | Elko,, Nevada USA September 24, 2008 Failure of incision and drainage alone to cure a cutaneous abscess, even one associated with cellulitis, usually results from inadequate drainage and debridement, not lack of antibiotic coverage. anant gandhi MD | Physician | Disclosure: None Armstrong Cable Services | pittsburgh, Pennsylvania USA September 24, 2008 Incision and drainage would suffice, but would culture the drainage and follow patient for complete resolution of the infection. Often in office practice MSSA staph aureus is not sensitive to cephalexin. Rick Rochetto Clinical Pharmacist | Other health professional | Disclosure: None Salem Hospital | salem, Oregon USA September 23, 2008 I/D alone in this patient population should resolve the infection. Antibiotics should not be used in this case unless the infection does not clear soon after I/D. I would culture with the I/D of course in case antibiotics are needed, but if the infection remains MRSA should be considered and treated as such. Jack Hawkins Dr | Medical student/physician in training | Disclosure: None Telewest Broadband | Birmingham, England September 23, 2008 no indications for antibiotic treatment just yet w hunter | Other health professional | Disclosure: None LenderLive | steamboat springs, Colorado USA September 22, 2008 nothing else has been shown more effective, antibiotics could hamper performance Nick Schneider | Physician | Disclosure: None University of Michigan Medical Center (MCIT) | Ann Arbor, Michigan USA September 22, 2008 High likelihood this infection will resolve w/ I and D alone/ low morbidity from holding antibiotic therapy. (does anyone really think this kid won't get completely better after just I and D?) Allen Frechette | Other health professional | Disclosure: None State of Minnesota | Shakopee, Minnesota USA September 22, 2008 Patient should be examined to rule out diabetes as a complication factor for staph infections. Incise and drain only if it appears lesion is ready to drain. Treat with Phisohex as a topical ointment for three days and reexamine. William Jantsch MD | Physician | Disclosure: None Road Runner | Mount Vernon, Ohio USA September 22, 2008 As an ER doctor I see lesions like this every day. I know that personal experience is no substitute for scientific analysis, but I have never seen a lesion like this NOT resolve with I&D alone. MRSA is the most common cause of these lesions in our central Ohio emergency department. Angela Kirwa | Other health professional | Disclosure: None Iowa Telecom | West Des Moines, Iowa USA September 22, 2008 I believe that treatment option 1 is sufficient for this otherwise healthy athlete. Antibiotics should be used only as necessary and indicated by positive cultures, or prophylactically as with some post-op clients. The overuse of antibiotics, as we know well today, has been a major factor in resistant organisms. It surprises me that some healthcare providors continue to prescribe antibiotic therapies without a confirmed bacterial infection. subhash SLATHIA | Physician | Disclosure: None JAMMU, India September 21, 2008 I do agree with all those comments of experts and add that my own boils once drained did not pose any problem. Need to be pressed till no frank pus comes. Robert Wolfson MD, MSHA | Physician | Disclosure: None Comcast Cable | Lakewood, Colorado USA September 21, 2008 Incision and drainage is adequate as a primary treatment. The patient has already been treated with amoxicillin. If there are further problems, antibiotic therapy should be considered. Antibiotics at this time could lead to a resistant infection. Mina Rim | Physician | Disclosure: None Medical Center of Delaware | Wilmington, Delaware USA September 21, 2008 It is highly likely that this patient has CA-MRSA cellulitis/abscess with its prevalence in the community and the patient's exposure to multiple skin flora as a basketball player. However, the lesion is small (5cm), systemic symptoms are absent and the patient is otherwise young and healthy. It would be reasonable in this situation to treat with I&D only and forego systemic antibiotics. Ann Weissman MD | Physician | Disclosure: None University of California at Berkeley | San francisco, California USA September 24, 2008 My practice is primarily with patients in this age group, and I see a lot of patients with similar problems. They frequently respond to incision and drainage alone; when they do not, they often have MRSA. So my choice would be incision and drainage with culture and sensitivity and close follow-up; followed by the appropriate antibiotic if the cellulitis does not resolve in a timely manner, if the patient becomes systemically ill, or if additional cutaneous infections develop. yousef hijazi dr | Physician | Disclosure: None mecca, Saudi Arabia September 21, 2008 Incision and drainage is the best with taking culture and sensitivity from pus Hans Kollberg Professor emeritus | Physician | Disclosure: None Telia Network Services | Uppsala, Sweden September 20, 2008 Never add an antibiotic if not necessary - it will only increase the burden of antibiotics and promote antibiotic resistance. Reconsider if not better after 3- 4 days. Olaf West van | Physician | Disclosure: None Pop Den Bosch, Ring Den Bosch | Breda, Netherlands September 20, 2008 Incision and ample drainage should be sufficient, take a culture and give no antibiotics , gives no resistance. saswati mukherjee sash | Medical student/physician in training | Disclosure: None CHINANET Sichuan province network | kolkata, India September 20, 2008 i feel that since the general condition of the patient is normal, and he has no other complications, simply incision and drainage is required. he has still a week left for his game, if complications occur, it can be dealt. simply prescribing antibiotics in this healthy , young patient wont be that useful, further causative agent and its sensitivity towards anti- microbial is also not confirmly known. David Berry | Physician | Disclosure: None Smart Systems for Health Agency | Sault Ste. Marie, Ontario Canada September 19, 2008 more detailed enquiry re:possible use of anabolic steroid injections and consideration of testing for hep and HIV depending on clinical suspicion. Another "old fashioned" addition is heating a large volume, narrow neck glass bottle and then placing the mouth of the bottle over the head before and after incision. As the bottle cools the negative pressure aspirates material rather than trying to push it out. tracy bramlette | Physician | Disclosure: None Comcast Cable | san francisco, California USA September 19, 2008 no antibiotics are needed if adequate i and d is performed James Stone | Physician | Disclosure: None Road Runner Business | Caribou, Maine USA September 19, 2008 Treatment of an abscess is drainage. I am disturbed that none of the solutions were written by a surgeon. Arved Weisswange | Physician | Disclosure: None France Telecom | Aigues Mortes, France September 19, 2008 I&D plus C&S is most appropriate.Complete cure is more important than the next match in a week.If one moves too fast one might loose time. Salvador Beris | Physician | Disclosure: None America Online | Tampa, Florida USA September 18, 2008 Only incision and drainage.I do not think that I will use any antibiotics at this time Peg Dash Fab | Other | Disclosure: None Rice University-Sesquinet | Houston, Texas USA September 18, 2008 Who among us has never had a pimple on his butt? Rubbing alcohol, bacitracin ointment, and a band-aid should suffice to clear this up. bill rogers | Physician | Disclosure: None SBC Internet Services | muskogee, Oklahoma USA September 18, 2008 I and D alone is adequate after 24 hrs of "poultice". Bonnie May RPh | Other health professional | Disclosure: None PAETEC COMMUNICATIONS | Worcester, Massachusetts USA September 18, 2008 I agree with everyone who has recommended I&D with C&S, keeping the addition of antibiotics as "Plan B" if the culture & sensitivity come back as MRSA. yu wang | Physician | Disclosure: None Beijing, China September 18, 2008 NTM infection should be considered for the shape of the ulcer is like a crater. Di Holdsworth | Other health professional | Disclosure: None Thessaloniki, Greece September 18, 2008 I and D then pour neat salt into the incision after drainage and leave uncovered. This hurts like hell for a minute but the patient will survive, the remaining bacteria will not! Cheap & effective and used in ancient Greek medicine. SATHURAGIRI CHAIRMARAJ MBBS | Physician | Disclosure: None NIB (National Internet Backbone) | TUTICORIN DISTRICT, India September 18, 2008 No other co existing disease and there is no systemic involvement.The lession is local & evident jamie calder | Physician | Disclosure: None iiNet Limited | sydney, Australia September 18, 2008 I & D alone in healthy young male, with culture. Why give antibiotics and contribute unnecessarily to emergence of resistant strains unless have bloody good reason. Frank Ruiz MD | Physician | Disclosure: None Comcast Cable | Cupertino, California USA September 20, 2008 The cure rate with adequate incision and drainage alone is extremely high and is not increased by the administration of oral antibiotics. He does not have an overt cellulitis, nor is there any sign of toxicity, so there is no need for antibiotic therapy. There would, however, be a benefit to culturing the abscess for MRSA since many patients with MRSA have a high rate of subsequent soft tissue infection. Tom Perry M.D.,C.M. | Physician | Disclosure: None TELUS Communications | Vancouver, Brit. Columbia Canada September 18, 2008 I would expect resolution with drainage alone, and quite promptly. This strikes me as a low risk situation for bacteremia, in comparison with many other serious S. aureus infections which are recognized late, or under treated, because patients and doctors do not understand the significance of pain with fever, or of "low grade fever" influenced by abundant use of antipyretics (NSAIDs, acetaminophen, ASA, corticosteroids). In the absence of nearly immediate improvement/resolution with drainage, one could still add an antibiotic for spreading cellulitis, increased fever, or malaise/toxicity. My father drained a similar "boil" on the back of my neck during a 1966 camping trip and I have never forgotten the instantaneous relief which followed a brief sear of pain from the (sterilized) pocket knife blade. It's a very satisfying action for a competent physician to perform. Joseph Finkler MD | Physician | Disclosure: None Telus Corporation | Vancouver, Brit. Columbia Canada September 20, 2008 Regardless of the etiology (MSSA or MRSA) of this superficial buttock abscess, incision and drainage and insertion of a short length of ribbon guaze is all that is necessary at this time. I know this from my work in the emergency department of a downtown teaching hospital, where the most common diagnoses are cellulitis and cutaneous abscesses. The majority of our indigent and addicted patients will not make the effort to fill a prescription for antibiotics and/or take them as prescribed, even if they do. And amazingly, the majority of the abscesses resolve. However, our practice pattern is to take a swab of the abscess and send it for culture and sensitivity testing. That way we will know which antibiotic to use, if the infection does not resolve. C. Peter Crowe | Physician | Disclosure: None Covad Communications | Tucson, Arizona USA September 18, 2008 Would be much happier with this decision if the lesion showed some fluctuance. May be draining a day prematurely. Jack Arbiser | Physician | Disclosure: None BellSouth.net | Atlanta, Georgia USA September 20, 2008 I frequently see MRSA abscesses and they respond to I and D alone. An additional measure of safety might be provided by painting the inflamed area around the drainage site with gentian violet, which kills MRSA Ricardo Savaris Ricardo Francalacci | Physician | Disclosure: None Porto Alegre, Brazil September 18, 2008 At least this is what I do in clinics, I would suggest warm pads to accelerate a point of flutuation and then incision and drenaige Janet Arrowsmith MD | Physician | Disclosure: Financial tie to maker of a related drug or device Valor Telecommunications Enterprises, LLC | Ruidoso, New Mexico USA September 18, 2008 I D with C&S, including viral C&S. HSV has certainly been reported in other contact sports, particularly football and wrestling. Make sure you have his contact information for appropriate follow-up as needed. James Williams | Physician | Disclosure: None SBC Internet Services | San Antonio, Texas USA September 18, 2008 Lesion clinically consistent with MRSA infection with evidence of cellulitis (by definition erythema, tenderness, >2cm) therefore requires I&D (to include margins), irrigation, packing routinely, and Clindamycin 300 q6hrs for 5 days with followup in 3-5 days. Cultures optional because will adjust treatment on clinical response. Caution player and teammates about hygiene and care of early lesions. mohamad elshafii dr | Medical student/physician in training | Disclosure: None Ramsis-Zone-DSL | mansoura DK Egypt, Egypt September 18, 2008 hence the patient is young and immunocompetent with no chronic diseases, incision & drainage with follow up is enough supported by the small size of affected skin . antiallergic medication may be helpful. JEFFREY MARMELZAT M.D. | Physician | Disclosure: None Impulse Internet Services | LOS ANGELES, California USA September 16, 2008 I WOULD ADD C&S AFTER I&D IN CASE IT DOES NOT RESPOND TO I&D ALONE OR BECOMES WIDESPREAD jose rojas jober | Medical student/physician in training | Disclosure: None neiva, Colombia September 18, 2008 in my opinion the case should be trated Drainage the abscess, and wait for a 24-48 hours resolution of cellulitis by the Swell lineal. takehiko dohi | Physician | Disclosure: None umassmed.edu | worcester, Massachusetts USA September 12, 2008 Just drainage is not enough in this case.To prevent the recurrence, complete debridement including the capsule is definitely necessary. This also makes wound healing faster. melissa tlougan | Other health professional | Disclosure: None Mayo Foundation | rochester, Minnesota USA September 12, 2008 Have this condition and is chronic, drainage is the best method I have found, anti-mrsa drugs do not always work! Abdu Sharkawy | Physician | Disclosure: None Toronto, Ontario Canada September 12, 2008 Given the absence of systemic symptoms (apart from possibly low-grade fever) and assuming that there are no similar clinical presentations reported by teammates/close contacts, there is no compelling reason to initiate therapy beyond I & D or to assume that this would represent CA-MRSA infection. Culturing the lesion with I & D followed by observation alone should suffice. David Mathison | Physician | Disclosure: None COMPEX Corp. | Washington, DC, Washington DC USA September 18, 2008 In an afebrile immunocompetent patient with a lesion on a location that is not over a joint and without a cellulitic component, I&D without antibiotics should be sufficient assuming proper follow-up is established. Jeannot Dumaresq | Medical student/physician in training | Disclosure: None Bell Canada | Quebec, Quebec Canada September 12, 2008 + open prescription if it doesn't get better by 1 or 2 days (if the pt is reliable) For the moment, we do not have a lot of CA-MRSA in Quebec. chandravadan ajmera | Physician | Disclosure: None NIB (National Internet Backbone) | Rajkot, India September 18, 2008 while practicing in developing countris like india; this seems to be the best alternative. we get the desirable results most of the times. however if patient does not respond we may thik of giving the antibiotic at later time. barry fox | Physician | Disclosure: Financial tie to maker of a related drug or device University of Wisconsin Madison | madison, Wisconsin USA September 12, 2008 choosing a 5cm size is potentially misleading........if you chose 7 cm..........option 3 would be the answer..............just at the 5 cm cutoff makes the answer more difficult Allison Enwright | Other health professional | Disclosure: None Columbia Health Care | Derry, New Hampshire USA September 12, 2008 For an uncomplicated skin infection in this young, healthy man, I&D with a C&S sent and patient education should suffice, with an early follow up. Rui Pereira | Medical student/physician in training | Disclosure: None NOVIS Telecom, S.A. | Lisboa, Portugal September 8, 2008 No antibiotics inicially. Get swab culture for ID. Uday Paul | Physician | Disclosure: None Chicago, Illinois USA September 12, 2008 I must admit to treating MANY of these in a military setting with incision and drainage and MRSA coverage (my favorites were TMP/ SULFA and/or Clindamycin). However I also had heard many accounts of these sort of abcesses being treated by I+D alone. and I must say that the logic is compelling to treat such an abcess as a surgical problem rather than a medical one. Sumire Sakabe Dr | Physician | Disclosure: None Birmingham, England September 8, 2008 Localised infection, likely to resolve with drainage (send for MC&S). Close observation and if not improving or worsening in the next 24-48h, for oral anti-MSSA treatment. In light of increasing numbers of CA PVL MSSA/MRSA, would be advisable to create awareness among the team members regarding recurrent boils. mehnaz mehboob | Physician | Disclosure: None glasgow, England September 8, 2008 localised infection with possible pus collection. I&D should be enough. patient systemically well. dose not need an extra course of anitbiotics Steve Croy | Physician | Disclosure: None Global Crossing | Highwood, Illinois USA September 8, 2008 I would add local wound care with chlorhexidine. If his wound did not improve or worsened an appropriate antibiotic could be started. Avoiding contamination of shared atheletic facilities, such as toilets, showers and seating areas should also be discussed with the patient. Daniel Winter MD | Physician | Disclosure: None Uberaba, Brazil September 12, 2008 Incision and drainage alone are probably most appropriate, since the patient has no systemic complaints and antibiotics would probably do nothing but favour antibiotic-resistant strains. It looks like most physicians are reading too much but lacking judgement as to make proper use of what they learn. Michael Bateman | Physician | Disclosure: None Comcast Cable | Tacoma, WA, Washington USA September 7, 2008 Incision and drainage, culture wound and nostrils. Inform all teammates to be vigilant in search for pustules. Eradicate, isolate if spreads among team. romero roberto rr | Physician | Disclosure: None MegaCable SA de CV | cd, obregon, son, Mexico September 7, 2008 by guidelines and personal experience the best treatment option is dreaneage and curatege twice a day. the patient has no other comorbilities that might affect the results. RANJIT MOHITE | Physician | Disclosure: None KHOPOLI, India September 7, 2008 i will like I/D and antibiotics if has systemic signs or C/S positive in this 20 Yrs.Immunocompetent male. Hassan Al-Eid | Physician | Disclosure: None King Faisal Specialist Hospital and Hospital | Riyadh, Saudi Arabia September 12, 2008 This is uncomplicated skin infection in healthy indivisual, I&D is the most evidence based option and should be more than adequate Federico Vancheri | Physician | Disclosure: None Caltanissetta, Italy September 7, 2008 Incision and drainage are sufficient followed by 48 hours wait and see for systemic signs Nelson Velez Dr. | Physician | Disclosure: None Cogetel Online | Phnom Pehn, Cambodia September 7, 2008 I would go for Incision and drainage and a close follow up, I think we are used to prescribe antibiotics more than we need to, however in medicine we make decisions based on experience, madical data, and mainly based on the individual patient. This is a young basketball player,healthy, with no need for antibiotics for the time being. Dan Mielnicki | Physician | Disclosure: None USUHS | Suffolk, Virginia USA September 7, 2008 This patient with a small "virgin" abscess without any reported co-morbids, surrounding cellulitis, or documented fever will almost certainly recover promptly following simple incision and drainage with appropriate wound care instructions. Culture of the wound seems prudent but depending on local MRSA prevalence this step (and added expense) might be avoided along with the antibiotics. alex rodway | Physician | Disclosure: None Imperial College London | london, England September 7, 2008 In my experience, intravenous antibiotics are not usually necessary in abscesses uncomplicated by widespread soft-tissue infection. Rihi Herewila | Physician | Disclosure: None PT Telekomunikasi Indonesia | Kediri, Indonesia September 7, 2008 the patient has not complaint and was not fever, so there is no reason for antibiotics administration except the result of C/S test were positive. Delores Nobles | Other health professional | Disclosure: None Pitt County Memorial Hospital | Greenville, North Carolina USA September 7, 2008 In the case of a healthy 20 year old, antibiotic therapy is not indicated at this time. With I/D, the wound bioload would be reduced to allow the natural healing process to take place. In the event the soft tissue wound progresses, antibiotic therapy adjunct should be considered. robert Carter | Physician | Disclosure: None Department of Veterans Affairs | Washington, D.C., Washington DC USA September 7, 2008 In addition to the I&D a bacterial culture should be sent to the lab for culture & SENSITIVITY. Don Gentry DDS | Other health professional | Disclosure: None SBC Internet Services | Corpus Christi, Texas USA September 5, 2008 I would culture the drainage and do sensitivities on it, to see if MRSA was present, and what therapy it would respond to, if the infection did not clear, or worsened. Also, I would recommend hot-water irrigation or hot packs to aid in suppuration, pointing, and cellular migration to the site. Johnathon Ross MD | Physician | Disclosure: None Toledo, Ohio USA September 7, 2008 This young man gives a preference for not taking pills. Given the likelihood of resolution with I and D alone I would start with this choice. He needs early follow up and careful instruction regarding red flag symptoms such as fever, persistent pain redness or new lesions. Cultures should be obtained and if MRSA is present then added discussion of the risk vs.benefits of anibiotics should be considered and antibiotics given if the patient prefers. There is also the issue of exposure to others on the team and potential for spread should be part of the discussion of risks and benefits to treatment. Steve Zanders, DO FCCP Steve | Physician | Disclosure: None Sprint PCS | Coopersburg, Pennsylvania USA September 4, 2008 I would incise and drain only, with appropriate follow-up. In addition, I would not culture the wound unless exudate was obtained deep in the incision. I Fear that skin contaminant/colonization would complicate the process. Antibiotics are needed only when mechanical cure is ineffective or systemic adversity occurs. Jose Campo | Physician | Disclosure: None University of Texas | Harlingen, Texas USA September 4, 2008 An lesion like that should improve only with incision and drainage Paula Azeredo | Physician | Disclosure: None TVCABO-Portugal Cable Modem Network | Lisboa, Portugal September 5, 2008 An abscess, or a furuncle seems to be the dignosis. Drainage when it will be "mature", as for the moment it has no fluctuation and, meanwhile, a topical antibiotic for ex. fucidic acid, seems to be the best aproach. A culture of the pus, for epidmiologic reasons if he get worst, should be done Helen Spratt Ms | Other health professional | Disclosure: None NTL Internet | Belfast, Ireland September 4, 2008 Incision and drainage with swab for O & S. Review required as spreading infection and mild pyrexia with likely increased heart rate for a fit athlete suggesting systemic involvement. Antibiotics required pending organisms and sensitivity and if continued spread of infection. Nicholas Sadovnikoff | Physician | Disclosure: None Partners HealthCare System | Boston, Massachusetts USA September 4, 2008 Would follow closely post-drainage and have a low threshold for initiating antibiotics (anti-MRSA) if the lesion does not resolve clinically as expected. MD Guilherme Fazolo MD | Physician | Disclosure: None Internet by Sercomtel S.A. | Londrina Parana, Brazil September 4, 2008 The drainage alone is enough for treatment of abscesses in healthy patients.Antibiotic use has a lot of complications that can be avoided. With a close observation of the evolution of the inflamatory process if there is an evolution to celulitis ,apropriate antibiotical use can be initiated in these subjects. Silvio Pitlik MD | Physician | Disclosure: None Tel Aviv University Network | Petah Tikva, Israel September 4, 2008 The fact that all treatment options still include "incision and drainage" mandate a word of admiration for the pioneers of this modality: Hippocrates (460-377 BC), Claudius Galen ( 1st century AD), Ambrose Pare (1510-1590),Johann Schultes (1595-1645), and others. Elizabeth Steiner | Physician | Disclosure: None Oregon Health Sciences University | Portland, Oregon USA September 4, 2008 Overuse of antibiotics is a major public health issue. Refraining from using them when possible is in the best interest of both the patient and the community. Treatment without antibiotics is appropriate for this patient, along with close monitoring for resolution of the abscess & cellulitis. Steven Smith Pharm.D. | Other health professional | Disclosure: None University of Florida/University Medical Center | Gainesville, Florida USA September 7, 2008 Given the uncomplicated nature of this infection in an otherwise healthy young adult, incision & debridement alone should be sufficient. Antibiotic therapy is often used on top of I&D as "mop-up" therapy, but the evidence supporting this practice is lacking in this type of case. Furthermore, this practice will invariably select out resistant strains putting the patient at greater risk for future infections. Does the patient's desire to resolve his infection before the next game mean that we should throw antibiotics on board? This sounds akin to prescribing antibiotics for children when the suspected pathogen is viral, simply because the parents expect antibiotics. John Edwards | Other health professional | Disclosure: None Rockford, Illinois USA September 4, 2008 The mild fever supports the notion that the body is fighting off the infection effectively. He is a young athlete with a strong immune system- I&D and let the body do its thing. Pedro Rito DMD | Other health professional | Disclosure: None Cabovisao, televisao por cabo, SA | Coimbra, Portugal September 4, 2008 I&D (with proper antiseptic, i.e. Betadine) followed by C&S. Add Ibuprofen for Pain/Inflammation. Observe in 48h. If more systemic signs appear or complicate (such as fever) then add the proper antibiotic suggested by the antibiogram. In either case, full strength for his next basketball game in 1 week's time will be hard to achieve. Paul Cook MD | Physician | Disclosure: None Pitt County Memorial Hospital | Greenville, North Carolina USA September 4, 2008 Antibiotics would be indicated if there were signs of sepsis or if there were signs of superimposed cellulitis. Neither exists in this case. keesler biloxi | Physician | Disclosure: None CABLE ONE | biloxi, Military (AA) USA September 4, 2008 the primary Tx of any abcess involves I&D. Uncomplicated abcess <5cm have not shown a better effect with concomitant Abx therapy and thus is not indicated at this time Asghar Naqvi | Physician | Disclosure: None Longwood Medical Area | Boston, Massachusetts USA September 4, 2008 Less is more. Wound cultures of the I&D should be sent to the lab. If he shows signs or symptoms of complications (i.e. fever, chills, increased area of erythema, purulent drainage), then culture-guided antibiotic therapy can be considered at that time. Steven Ebert PharmD | Other health professional | Disclosure: None SupraNet Communications | Madison, Wisconsin USA September 4, 2008 Would not feel comfortable using an antibiotic without susceptibility data. Suggestive of MRSA, but ?activity of clindamycin or TMP/ SMX? Thomas Morgan | Physician | Disclosure: None Vanderbilt University | Nashville, Tennessee USA September 4, 2008 Simple incision and drainage would be my first line treatment, but I would add an antibiotic, most likely dicloxacillin, if the patient did not have a dramatic improvement by the next day, with persistent areas of heat, pain, and redness prompting me to activate a prescription. I'd have the patient keep the wound open for 1-2 days and change the dressing daily. Starting an antibiotic right away is not necessary. Dongmi Park | Medical student/physician in training | Disclosure: None New York University | Fresh Meadows, New York USA September 4, 2008 It would be optimal if I can collect culture and sort out the organism before starting any antibiotic. Roman Palacios Dr. | Physician | Disclosure: None UNITEL S.A E.S.P | Cali, Colombia September 4, 2008 a recent study showed that incision and drainage is enough to manage this type of cases and that there was no difference with the use of antibiotics. r finaggan ms. | Other health professional | Disclosure: None America Online | chicago, Illinois USA September 4, 2008 Research appears to show that antibiotics are not needed in a healthy young person who is not immunocomprimised. I&D should be sufficent due to no symptoms of infection and the pt.'s health status. Vandana Niyyar | Physician | Disclosure: None THE LEUKEMIA & LYMPHOMA SOCIETY | Atlanta, Georgia USA September 4, 2008 I would start with an I and D only, get cultures and susceptibility from the wound as well as the blood and then treat with antibiotics only as needed Arthur Frank MD | Physician | Disclosure: None University of Illinois at Chicago | Chicago, Illinois USA September 4, 2008 This option is simplest and most scientifically correct in the circumstances where drainage is available, practical and successful. In pediatrics (my field) we have the problems of emotional trauma and physical difficulty with many procedures plus early presentation before localization. Therefore drainage is often deferred or incomplete/unsuccessful and the use of antibiotics becomes routine even when option one is actually preferred in theory. Charles Bodmer | Physician | Disclosure: None Colchester, England September 4, 2008 There is no clear need for systemic antimicrobial therapy for this young man. C&S at time of I&D will provide future guidance for therapy if required. The patient has also made it clear that he does not want systemic therapy, and may well not take them even if prescribed, when it is explained to him that there is controversy over the need. Wakinyjan Tabart | Physician | Disclosure: None Netspace | alice Springs, Australia September 4, 2008 let's avoid over-using antibiotics in an otherwise healthy young man and try to avoid increasing resistance in staph bacteria to first line antiobiotics- if the patient had diabetes, chronic kidney disease or other risk factors for a less favourable outcome then I would consider adding antibiotics Trish Westbrook, FNP NP | Other health professional | Disclosure: None CHARTER COMMUNICATIONS | Gainesville, Georgia USA September 4, 2008 Recent literature indicates that most cutaneous lesions, even MRSA, will resolve with I&D alone. el samad youssef | Medical student/physician in training | Disclosure: None Centre Hospitalier Universitaire Amiens | amiens, France September 4, 2008 antibiotics are not necessary in treating uncomplicated staphylococcal skin infections Andrew Morris MD, MSc | Physician | Disclosure: None Performance Systems International | Toronto, Ontario Canada September 7, 2008 The recent RCT from San Francisco--showing resolution without "effective" antimicrobial therapy--is compelling. That patients can get complications from antimicrobial therapy (allergic reactions, C. difficile, etc.) is even more compelling. With the principle of primum non nocere, it is difficult to support giving antimicrobials when the anticipated outcome with incision and drainage alone is cure. Muhammad Munir | Physician | Disclosure: None Karachi, Pakistan September 4, 2008 If the abscess is drained adequately the antibiotics are not needed. Ville Lehtinen | Physician | Disclosure: None Kansanterveyslaitos (National Public Health Instit | Lahti, Finland September 4, 2008 With no signs of generalized infection, and given the small volume of the abscess, incision and drainage should be enough. This treatment also prevents from disposing the patient to the harmful side effects of antimicrobial therapy. M JAWEED MD | Physician | Disclosure: None MyKRIS Asia Sdn Bhd | KUALALUMPUR, Malaysia September 4, 2008 well in my opinion , there is no evidence showing that, antibiotics will help and provide more rapid cure for non complicated skin abscess; as surgeon i will recommend I&D plus C&S and add painkiller for post I&D pain. Dorothy Hight | Other health professional | Disclosure: None GCI Communications | Anchorage, Alaska USA September 4, 2008 Should do hot soaks, bring abscess to a head, I&D with packing. Culture & tx with antibx if abscess does not resolve. Like it or not, lesion may require time off the athletic field to heal, regardless of Rx. Pt. does not like to take medicine; risks high for incomplete Rx, ineffective tx, eventual resistance, and a bottle of unused pills lying around to be inappropriately used by someone else at some day in the future. Hold antibx also until after C&S returns: may have acquired infxn in someone else's community, with different disease patterns. On re-check, choose to add antibx if cellulitis not responsive. Nearly every abscess I have seen has looked like a tense cellulitis before it was ready to lance. Dirk Keldermans | Other health professional | Disclosure: None TELE2 Belgium | Waremme, Belgium September 4, 2008 Often a drainage, in combination with Iso-Betadine-irrigation, will satisfy. Using antibiotics is only useful if the infecting bacteria is known and if the drainage doesn't resolve the problem. It's important to prevent AB-resistance, so using AB must be limited where possible. Giraud Alice | Other health professional | Disclosure: None COLT Internet CH networks | Geneva, Switzerland September 4, 2008 During the incision, take some liquid to make an antibiogram. Then depending on the outcome of the antibiogram decide if antibiotic treatment is necessary and which is the most appropriate. Niklas Storck | Physician | Disclosure: None Bredbandsbolaget | Stockholm, Sweden September 4, 2008 We should really try to avoid the use of antibiotic agents if not neccecary. Incision combined with drainage should be suficcient. A culture should be performed if the patient by any chance should get more infected later. Martin Xavier Doré Martin Xavier | Physician | Disclosure: None France Telecom | Le Havre, France September 4, 2008 I would first treat him by incision and drainage, and see him after 48 h to decide if antimicrobial therapy is necessary. My decision for oral therapy will be guided by results from cultures and clinical evolution. Doubravka Kostalova MD | Physician | Disclosure: None CESNET, z.s.p.o. | Prague, Czech Republic September 4, 2008 Incision, drainage, culture and susceptibility testing, proper antiseptic. Antibiotics only in case of worsening and culture positivity. Rajesh John MBBS, MD | Physician | Disclosure: None Oman | Muscat, Oman September 4, 2008 I&D but must be followed up with regular wound inspection and dressings Charles Gillbe MB FRCA | Physician | Disclosure: None British Telecommunications | London, England September 4, 2008 Option 2 is muddled and there is a lack of evidence to support option 3. Where, for instance, does the idea that speed of recovery will be enhanced come from? Adan Atriham | Physician | Disclosure: None Baptist Memorial Health Care Corporation | Houston, Texas USA September 4, 2008 I&D, get C&S, f/u in 2 or 3 days, if cellulitic rash or systemic symptoms occur treat according culture result. Sergey Shlyapnikov | Physician | Disclosure: None Saint-Petersburg, Russian Federation September 4, 2008 This athlete has uncomplicated (without systemic signs) skin infection. It is main reason don't use systemic atibiotic therapy. Natalie Hendricks | Physician | Disclosure: None Telkom SA Ltd. | Durban, South Africa September 4, 2008 I guess most physicians favoring antibioitc treatment will come from areas with high incidence of MRSA. This could be argued from a Chicken and Egg perspective as the high incidence of MRSA probably comes from previous overuse of antibiotics. Krispin Hajkowicz MBBS | Physician | Disclosure: None Northern Territory Government | Darwin, Australia September 7, 2008 Based on two RCTs (a luxury for skin and soft tissue infections) incision and drainage alone is adequate therapy and will reduce cost, prevent adverse effects from antibiotics and prevent the emergence of even more bacterial resistance in the future. Pus from the abscess should be sent at the time of the incision and drainage to guide antibiotic selection if the patient represents with a deterioration. Barry Lerner | Other health professional | Disclosure: None Optimum Online (Cablevision Systems) | Rye, New York USA September 4, 2008 There's always time to prescribe antibiotics if I&D alone fails; why initiate it prior to such eventuality? In addition, waiting will give us the results of culture and sensitivity, so that the appropriate medication may be administered. Federico Altuna | Medical student/physician in training | Disclosure: None CTI Compania de Telefonas del Interior S.A. | Salto, Uruguay September 4, 2008 The infection this patient presents is probably a MRSA infection. The patient has not compromise of his immune system, and no fever. Evidence indicates that, in an abscess, if incision and drainage are achieved successfully, there's no need of antibacterial treatment. That is because an abscess is a collection in a newly formed cavity, so it doesn't imply systemic compromise. I do believe a culture should be done, in order to knowing the bacteria involved in case the patient doesn't heal with drainage. The use of antibiotics should be avoided when possible because the more we use them the more resistance we generate. With regards to side effects, the combination of TMP/SMX is very well tolerated by the patients. I would worry more about resistance. I apologyze in advance for possible spelling mistakes or for misuse of medical language. I'm not an English native speaker and, even though I've studied the language for years and taken international examinations, I have finished my studies some years ago and I don't have formation in medical English Thomas Reynolds MD | Physician | Disclosure: None Road Runner | Palm Desert, California USA September 4, 2008 I&D with culture. Wait two days for culture results. Re-evaluate pt, and prescribe appropriate antibiotic if clinical response to I&D has been unsatisfactory. Jennifer Christian | Physician | Disclosure: None Comcast Cable | Wayland, Massachusetts USA September 4, 2008 Initial treatment choice is not necessarily the end of the episode or treatment options. The development of MRSA has been made possible by over-use of antibiotics, so I would not begin there. I would ask this patient to talk with other players about any problems they have had -- and request a report back. That will enable me to make another choice later, but only if indicated. Mary Ann Banerji | Physician | Disclosure: None Brooklyn, New York USA September 4, 2008 I would chose and I& D only and follow the patient clinically- cultures can be taken at the time . If he does not respond I would reassess the patient clinically and start antibiotics. That he has to have antibiotics to be ready for basketball is not a consideration Jonathan Mittelman MD MPH | Physician | Disclosure: None Old Lyme, Connecticut USA September 4, 2008 Without signs of cellulitis extending beyond the site of the abscess, simple incision & drainage with close follow-up should be sufficient treatment. SHARAT SAMANTRAY DR | Physician | Disclosure: None Oman | IBRI, Oman September 4, 2008 COMMUNITY ACQUIRED MRSA INFECTION TYPICALLY PRESENTS IN YOUNG ATHLETES, WITH THIS SEVERITY I&D ALONE IS SUFFICIENT. Luis Rodríguez Gutierrez Dr. | Physician | Disclosure: None MegaCable SA de CV | Guadalajara, Mexico September 4, 2008 I think is better to take a sample to make a direct examination, a gram and culture, to ruled out anothes agents plus Stafilococous aureus. Claire Nunes-Vaz MD | Physician | Disclosure: None Toronto, Ontario Canada September 4, 2008 I+D and culture and observe. College students are notoriously non-compliant with meds and if he were to get better in 3 days with antibiotics he might well stop them. If c+s helps and he is not improving I would add the meds as dictated by the culture. Yousef Binamer | Medical student/physician in training | Disclosure: None McGill University | Montreal, Quebec Canada September 4, 2008 Since he is young and healthy without signs or symptoms of toxicity I will do I& D and will check the culture and in one week if he is not improving I will give him the appropriate antibiotic. Gary Dunn MD | Physician | Disclosure: None America Online | Shreveport, Louisiana USA September 3, 2008 As this patient does not have systemic symptoms or a large area of surrounding cellulitis I+D alone should be sufficient if done correctly followed by local wound care. Antibiotics may be added after 48 hours if there is not significant improvement or sooner for worsening. A culture should be done at I+D to direct antibiotic therapy if needed. He is not going to be ready for his game in one week regardless of therapy and if this is MRSA consideration should be given to holding him out of contact activities until the acute response is cleared. JimmieJoe Izanec MD | Physician | Disclosure: None SBC Internet Services | Pepper Pike, Ohio USA September 3, 2008 I prefer to do a Gram stain and culture/sensi. Since the person is generally healthy I would I&D, await the culture results and have the person follow her temperature and symptoms/signs. Hung Yang MBBS | Physician | Disclosure: None OPTUS Customer Network | Sydney, Australia September 3, 2008 If antibiotics are unnecessary in a healthy patient, using them would appear to encourage development of resistant organisms. It would have been nice to have been able to exclude any possibility of Marfan's (and possible SBE risk) in a basketballer. It is noted that in practice it can be hard to avoid prescribing antibiotics for obvious bacterial infection; one option could be to arrange review of progress in 1-2 days time; another to provide a prescription to be filled only if resolution is slow. ashish kakaria dr | Physician | Disclosure: None sydney, Australia September 3, 2008 anitbiotics are not necessary for uncomplicated skin abscess Don Elliott M.D. | Physician | Disclosure: None Denver, Colorado USA September 3, 2008 Follow up temp and visual inspection daily, add antibiotic based on c&s if not rapidly resolving Jonas Moses | Other | Disclosure: None Cellco Partnership DBA Verizon Wireless | Austin, Texas USA September 3, 2008 Having spent several years in clinical Ophthalmology, within a military setting, I developed a rather conservative approach to treatment of localized infections. I tend to concur with Dr. Chambers in observing that this patient is young, health/active (immunocompetent), and has no confounding history. Given that well-documented evidence supports incision and drainage without the addition of antibiotics, and given the growing concern over the development of antibiotic-resistant organisms, a conservative treatment course seems the obvious choice, here. peter mahrer MD | Physician | Disclosure: None LA, California USA September 3, 2008 I & D plus culture and sensitivities will allow for proper choice of antibiotic were it to become necessary James Simon M.D. | Physician | Disclosure: None Tiburon, California USA September 3, 2008 get a c&s of wound Daniel Mendoza | Physician | Disclosure: None National Institutes of Health | Washington, Washington DC USA September 5, 2008 There is no evidence in this setting that antibiotics provide more rapid resolution of symptoms, prevent further spread of the infection, and prevent bacteremia with dissemination to other parts of the body. Indeed, they cause important side effects. The use of antibiotics for skin abscess has not shown to bring any benefit in 2 randomized trials, one of them including cases of MRSA infection. The biological explanation is that antibiotics cannot penetrate or work properly within an abscess and the resolution of symptoms depends on the elimination of the source of infection and the immune response. Treatment Option 1 Comments Treatment Option 2 Comments Treatment Option 3 Comments Treatment Option 2: Incision and drainage plus anti-MSSA therapy. 95 Readersʼ Comments Paulo Behar | Physician | Disclosure: None Porto Alegre, Brazil September 25, 2008 Criteria for incision and drainage plus antibiotic: local and systemic (37.7oC) inflamatory signs. Criteria for anti-MSSA tharapy: epidemiology (MSSA more prevalent than MRSA in the comunity), even when particularities of this specific patient are considered. In this case, patient´s opinion should be considered too. Peter Taylor MB.BS, FRCPA | Physician | Disclosure: None Eastern Sydney Area Health Service | Sydney, Australia September 20, 2008 It is common that staphylococcal skin infections spread among team players and simple drainage would not reduce the bioburden in the draining fluid. this man will be in mixing in changing rooms and in close contact with his team mates and the chance of secondary spread is significant. The comments about cellulitis also suggest that antibiotics may help in the resolution of his infection. José Acuña | Medical student/physician in training | Disclosure: None Santiago, Chile September 18, 2008 In my opinion the reason for adding anti-MSSA drugs is the extension of the infection in the skin (cellulitis). Abscess without extension of the infection should be treated with incision and drainage only. This patient presents cellulitis too. Cam Tu Nguyen Ms | Physician | Disclosure: None Ho Chi Minh, Vietnam September 25, 2008 As a gastrologist I have not many experiences about the lesions on skin, but when I saw that lesion I was sure that it have been caused by MSSA, which is so common actually, so that the treatment option 2 is the most suitable. Sambhu Dutta DR. | Physician | Disclosure: None chilka,balugaon, India September 23, 2008 to me incision with an antimicrobial with anti mssa activity like cloxacillin or 1st/2nd gen cephalosporin seems to be prudent. unnecessarily using potent anti mrsa antibiotics will soon create an extradrug resistant staph somewhat like XDR TB. Barbara Chaffee MD | Physician | Disclosure: None UHS Hospitals-Binghamton General | Binghamton, New York USA September 23, 2008 Would culture and change to MRSA therapy if culture shows MRSA prabhakara chaturvedula dr. | Physician | Disclosure: None CityOnline Services Ltd | bangalore, india, India September 22, 2008 i feel in a country like india, antibiotics are always prescribed, rusli nordin | Physician | Disclosure: None Johor Bahru, Malaysia September 22, 2008 I would add that the application of a topical Staph Aureus sensitive Sodium Fusidate, in addition to incision and drainage and oral cephalexin, appears to accelerate the healing process. francisco ortega | Physician | Disclosure: None guatemala, city, Guatemala September 22, 2008 I belive the option 2 is the best election. A tried some pacients just drainage and the cultive were mssa so they need drug theraphy i prefiere dicloxacilin Magdalena Maj | Medical student/physician in training | Disclosure: None Neostrada Plus | Poznan, Poland September 21, 2008 As a student I can observe many clinicians with broad experience. Quite often they forget Staphylococcal infections can be due to MSSA strains. To prevent antibiotics overuse I would choose in the patient anti-MSSA therapy in first place. Leonardo Lence Barbosa MD | Physician | Disclosure: None Vila Velha, Brazil September 21, 2008 Incision and Drainage Plus Anti-MSSA Therapy (with a cephalosporin like cephalexin) it is a good choice for that case. syed shah | Physician | Disclosure: None ibd, Pakistan September 21, 2008 this is staphlococcal skin infection leading to abscess formation.evidence suggests that a week long course of intravenous antibiotics (amoxycilline and clavulonic acid)will help to recover after incision and drainage. ravikiran tamragouri MD | Physician | Disclosure: None SBC Internet Services | downers grove, Illinois USA September 21, 2008 community acquired skin infections tend to be MSSA. In order not to over use antibiotics typically used for MRSA to avoid induction of resistance, antibiotic for MSSA seems appropriate, unless culture report indicates otherwise. Abdelhamid Mohammed | Physician | Disclosure: None Sudatel | Khartoum, Sudan September 21, 2008 Clinical trials.Mostly is not caused by MRSA strains Nicholas Okoh | Physician | Disclosure: None Leaf Ireland Ltd. | Tullamore, Ireland September 21, 2008 Though small localised abcess may respond well to incision and drainage alone. In this case with cellulitis with no drainable focus, it will be of benefit to add anti-microbial agent to the therapeutic regime to avoid spread of the infection. Vitull K. Gupta Dr. | Physician | Disclosure: None NIB (National Internet Backbone) | Bhatinda, Punjab, India September 21, 2008 The epidemiological reality of India is totally different where skin and soft tissue infections are very common. The routine management regimen followed by majority of primary care doctors is I & D with broad spectrum antibiotics and anti inflammatory drugs without any culture and sensitivity. The secondary and tertiary care doctors follow the above said regimen but they include the culture and sensitivity test. I strongly feel that treatment of skin and soft tissue infections are determined by local conditions and prevalent etiology along with cost effective factors. Regardless of the etiology (MSSA or MRSA) of this superficial buttock abscess, incision and drainage and insertion of a short length of ribbon guaze is necessary and in Indian setup must include antibiotic and anti inflammatory drugs with or without culture and sensitivity. Mariano Mazzei | Physician | Disclosure: None CABLEVISION S.A. | BsAs, Argentina September 21, 2008 Clinically, there is an abscess, and it should be drained. I think that the treatment failure is because of the suppurative skin complication. Community acquiered MRSA infections without treatment have a different outcome than the history given. Adriano Garcia RS | Medical student/physician in training | Disclosure: None NET Serviços de Comunicação S.A. | Porto Alegre, Brazil September 20, 2008 I believe, since the patient is young, imunocompetent and doesn`t present any important systemic reactions, the better option would be incision and drainage plus antibiotic (anti-MSSA) therapy, such as cephalosporin. Considering the higher incidence of MRSA infections in the community, the better choice would be waiting for the results from the culture exams, and in case of MRSA, change the antibiotic drug. Atul Sattur Dr | Other health professional | Disclosure: None NIB (National Internet Backbone) | Hubli, India September 20, 2008 I&D with Amoxycillin-Clavulunate 1 gram ,BID and Ibuprofen400mg+paracetamol 500mg TID for 5days is good enough, with daily dressing of the wound. Most important give Tetanus prophylaxis. Christopher Chen | Physician | Disclosure: None BellSouth.net | miami, Florida USA September 20, 2008 The possibility of a swifter resolution in pts where follow-up is not always assured encourages me to using some type of antimicrobial coverage. Silvia Corvera | Other health professional | Disclosure: None umassmed.edu | Worcester, Massachusetts USA September 20, 2008 The last boil with low grade fever I saw in an athlete (tennis player, late 50's, boil in back of neck) was treated non-aggressively. The patient developed a spinal epidural abscess and is currently paraplegic. In my opinion, a soft tissue infection + low grade fever should be treated immediately and aggressively with drainage and antibiotics. wei chih-hung | Physician | Disclosure: None CHTD, Chunghwa Telecom Co., Ltd. | Taipei, Taiwan September 20, 2008 better to treat with antibioctics for 1:prophylaxis 2:bactericidal effect 3:avoid legal problems in practice unless culture is free of bacteria.I & D hold until abscess mature Rupinder khurana MD | Medical student/physician in training | Disclosure: None Chandigarh, India September 20, 2008 If the infection is community acquired as in this case,it becomes mandatory to give antibiotics .It is because ,this patient being an athlete,would be playing in the worst of weather and other conditions related with hygiene,so other microorganisms could also cause the cellulitis.Cellulitis present in this case is sufficient for a clinician to decide for the antibiotic treatment with I/D.The antibiotic prescribed would be dependent on the result of the culture positivity for MRSA. Dukjae Kim | Physician | Disclosure: None Korea Telecom | Seoul, Korea (South) September 20, 2008 Incision and drainage may not be necessary in this lesion which is not so large immature abscess. Anti-MSSA therapy would be successful for this healthy man. Natália Castro | Physician | Disclosure: None Campinas, Brazil September 18, 2008 besides the patient has fever, he has a infection that isn't a local anymore but a sistemic one, so he really need a antibiotics treatmeant plus incision and drenage. Cindy hung | Medical student/physician in training | Disclosure: None Ministry of Education Computer Center | taipei, Taiwan September 18, 2008 For a localized abcess formation, surgical drainage is preferred than antibiotics alone. The risk of MRSA infection in this patient was no high, therefore empyric antibiotics after I&D could choose anti-MSSA first. subbiah kandsamy dr | Physician | Disclosure: None NIB (National Internet Backbone) | trichy, India September 18, 2008 most of the community acquired infections are MSSA ONLY Tanveer Ahmed Dr | Physician | Disclosure: None Grameenphone is the largest telecommunication Orga | Dhaka, Bangladesh September 18, 2008 As the central part is hard and having serrounding cellulitis then only incision and drainage will not be curative alone plus there is a history of taking amoxycillin within 7 days, so needs dicloxacillin. Desy Philippe | Physician | Disclosure: None LDCOM | Saint Nazaire, France September 18, 2008 Given the importance of cellulitis and the necessity of being fully physically active a week later, I 'll give my preference to drainage associated with a 5 days treatment of pristinamycine in order to limit the risicos of persisting pus drainage, otherwise local drainage and local chlorexidine would have been efficent sener barut | Physician | Disclosure: None tokat, Turkey September 18, 2008 this is a community acquired skin infection, so the etiologic agent is most likely Metisilin sensitive Staph aureus. Anti MSSA and drainage is reasonable and enough. Enrique Romero | Physician | Disclosure: None Globalnet.hn | La Lima, Honduras September 18, 2008 In answering we inevitably take our background and surroundings into account. I deal with banana plantation workers who often times have their wife and kids with lesions. Penicilin has seemed to work perfectly, but we have not done enough to erradicate bacteria from family group. We have been recently using dicloxacilin but cannot tell if this is really costeffective. Carlos R. Silva-Rosas MD | Physician | Disclosure: None Santiago, Chile September 20, 2008 I think in the epidemiological reality of my country. So a comunnity staphylococcal skin infection should be treated immediately with a Anti-MSSA therapy. However I would use local heat in the area of the abscess waiting the appropiate timing for the incision and drainage of a "mature" abscess in this patient alredy covereded with antimicrobial therapy. Gulsum Iclal Bayhan | Medical student/physician in training | Disclosure: None Turk Telekom | Ankara, Turkey September 18, 2008 I select treatment option 2. I also get cultures of abscess. If it was MRSA, I change antibiotherapy. Bil Randerson Bassetti | Medical student/physician in training | Disclosure: None Telemar Norte Leste S.A. | Vitória, Brazil September 18, 2008 incision + drenage and terapy anti-MSSA is a prudent strategy for the severe soft-tissue infection. luis gomez rosales | Other | Disclosure: None guayaquil, Ecuador September 16, 2008 treatment with dicloxaciline 500mg capsule, every 6 hours for 6 days, Eduardo A. Muñoz López | Physician | Disclosure: None Pasto, Colombia September 18, 2008 I choose treatment option 2, becouse I have been using this terapeutic alternative since 2 years, with excellent results in active soldiers with skin and soft-tissue infections, working in extreme heat and humidity locations and close contact with the inherent geographic conditons of Colombian jungle. Wang Chun | Physician | Disclosure: None Chengdu Hengyou Industry Co.Ltd | Chengdu, China September 12, 2008 The patient had fever with body temperature 37.7°C. If antibiotics was not used, nobody could guarantee that the infection didn't spread. I think oral antibiotics could be chosed. Leo Sham | Physician | Disclosure: None Kowloon, Hong Kong September 12, 2008 Consider a demanding patient with rapidly evolving abscess with surrounding cellulitis in an easily contaminated area (sweaty, buttock). Most patients don't come in with perfectly mature abscesses the require I&D per se. MRSA is not common in HK but most strains are keflex-resistent. IV rocephin + PO augmening/falgyl provide rapid resolution. Clorhexidine DELAYS wound healing! Mariellen Rodman MD | Physician | Disclosure: None Verizon Internet Services | Acton, Massachusetts USA September 12, 2008 Also, the patient should be asked about steroid injection as a possible etiology for the abscess, which raises the possibility of exposure to blood-borne infectious agents Praveen Cheripalli | Medical student/physician in training | Disclosure: None Department of Veterans Affairs | Urbana, Illinois USA September 12, 2008 This particular patient may or may not have an abscess. He also has signs of cellulitis. If the wound is not mature enough to become an abscess then only I and D may not be a good option. I would not agree to treat all the patients with skin infection for MRSA, in the first instance. I will start him on MSSA along with I and D and if he does not improve then will think of MRSA. Ezequiel Zaidel | Physician | Disclosure: None CABLEVISION S.A. | buenos aires, Argentina September 12, 2008 Drainage plus anti MSSA therapy seems to be the best option. Although drainage alone may solve most of the times this kind of soft tissue infection, the addition of an anti MSSA antibiotic eg. cephalexin shortens the healing time. Use of anti MRSA therapy as a first line treatment not only is more expensive and brings the risk of more serious side effects, but also generates bacterial mechanisms of resisitance. Thiruvengadam Ramakrishnan M.D. | Physician | Disclosure: None ETS TELEPHONE COMPANY | Richmond,, Texas USA September 18, 2008 Incision and drainage is the mainstay of treatment. Because the abscess is not yet formed (localized) and cellulitis is present, I would add an antibiotic. It might hasten recovery, which is crucial in this case. A short course of antibiotics would not add appreciably to expense, side effects or emergence of new drug resistance. Carlos Scarampi MD | Physician | Disclosure: None Intertec S.A. | Temperley, Argentina September 12, 2008 When you have an abcess you must drain it, and then use an antibiotic to treat the infection lilian muñoz marrugo | Physician | Disclosure: None bogota, Colombia September 12, 2008 in my media, mssa is still quite common; over 70% are responsiveness to it, besides the patient doesnt have any sistemic response so there's no hurry in upgrading the treatment Camelia Jalaskoski Mrs | Physician | Disclosure: None Tampere University Hospital | Tampere, Finland September 16, 2008 MRSA is not so common in Finland. Patient has fever and the generat status was not normal,so my opinion is that antibiotic need.And in my opinion im or iv. David Matley Dr | Physician | Disclosure: None Australian Department of Defence | Brisbane, Australia September 16, 2008 We are fortunate to have a very low incidence of community acquired MRSA. In the absence of fluctuation I would generally prescribe an antibiotic and refer for drainage when the abcess is "mature"(usually 24-48hrs). Raja Muthiah | Physician | Disclosure: None EUnet France | Chennai, India September 8, 2008 1.Hot fomentation followed by cleaning the area with soft antiseptic solution with a light dressing. 2.start systemic anti-MSSA therapy on the same day. 3.If flexuant,do I&D and sent swab for culture and sensitivity followed by simple dressing. 4.If possible, rest to the region is advisable. Dr.Guillermo Castrillo | Medical student/physician in training | Disclosure: None Juigalpa, Nicaragua September 7, 2008 Even though side efects do appear with the use of penicilin like antibiotics, they are not common, being more common the reinfecction of the site due to the fistula created bye the abscess, the constant sweating do to the atlethic activitys, and most important the site where the celulitis is; therefor i support the incision dranage plus anti mssa therapy Susheel Kapoor Dr | Medical student/physician in training | Disclosure: None MTNL CAT B ISP | Mumbai(Bombay), India September 8, 2008 I support option 2 since: 1. the lesion is an erythematous, firm and tender area without drainage; which means it is an area with cellulitis and possibly an organizing infection. 2. most uncomplicated skin infections in healthy individuals are caused by Streptococci or S. aureus susceptible to most antibiotics. Therefore, due to the organizing nature of the infection and the probability of it being caused by a susceptible bacterial strain I would support the treatment of the individual with option 2. Dr Susheel S Kapoor Resident doctor, Year 2 Mumbai (Bombay), India. Robert Bernat MD, PhD | Physician | Disclosure: None Zagreb, Croatia (Hrvatska) September 7, 2008 I had a similar infection myself. With oral antibiotic, it progressed to near-septic state. It resolved only after i.v. double antibiotic treatment and subsequent drainage. Always treat with antibiotics!! jose davis | Other health professional | Disclosure: None Verizon Internet Services | bethlehem, Pennsylvania USA September 7, 2008 I$d with app. antibiotic therapy, and cultures of wound and nares, for a young athlete who plays sports to would be the best treatment, with these cases I have seen if left, just continues to evolve into a deper abcess, and as a young person he prob. has a hx of not fininshing his antibiotics for prescribed time for his many sinus infect. leading to mrsa Jyoti Assudani | Medical student/physician in training | Disclosure: None Cambridge, Massachusetts USA September 7, 2008 I think surgical drainage is appropriate. antibiotic coverage is essential in the face of there being a possiblity of underlying infection. however anti mrsa therapy is not indicated since there is no proof of mrsa being present and anti mrsa therapy isnt warranted also because we dont want to create antibiotic resistance for future. Onder Ergonul MD, MPH | Physician | Disclosure: None Turk Telekom | istanbul, Turkey September 8, 2008 Community acquired MRSA rate is very low (1/1000) in many countries, like in Turkey. Julio Delgado | Physician | Disclosure: None CHARTER COMMUNICATIONS | Montgomery, Alabama USA September 7, 2008 I would do the Incision and drainage and start septra DS or a macrolide and await for culture and sensitivity. Eugen Hinterbuchner M.D. | Physician | Disclosure: None LAM plus s.r.o. | Prague, Czech Republic September 8, 2008 In the Czech Republic the prevalence of MRSA in outpatient departments is very low and therefore unnecessary to cover for initially. The cultures will provide further necessary information. Lakshman Khiria | Other health professional | Disclosure: None Ahmedabad, India September 7, 2008 Abcess (folliculitis) in the gluteal region is not an unusual problem. As a surgeon I frequently come across these patients. I personally use amoxicillin and Clavulinic acid combination at the first visit wait for 48 hrs if symtomatic improvement no I&D but if no improvement than I&D with antibiotic coverage.this patient is young with good general condition without comorbidities should recover in 3-5 days and will be able to resume his sports activity in a weeks period there is no reason for prolonged recovery. Ignacio Garcia-Valladares | Medical student/physician in training | Disclosure: None Guadalajara, Mexico September 7, 2008 Dicloxacillin! good tolerance and no AE, and maybe if the abscess matures, I and D would help..this is what we commonly see in mexico but we usually observe a good response with MSSA and I guess always be alert to clinical worsening. Michael Desjardins Mr. | Other health professional | Disclosure: None Qwest Communications | Salt Lake City, Utah USA September 7, 2008 Hello, I have a comment and question. I agree with the incision, drainage and anti-microbial option. I was wondering if anyone has experience with treatment of recurring abcesses. I have read that bactroban in the nasal cavities and a wash with chlorhexedrine can provide resolution but i was looking forward to comments on this or any other treatments found successful. Kavita Chankadyal | Physician | Disclosure: None Couva, Trinidad And Tobago September 7, 2008 Incision and drainage may be adequate therapy but the use of antibiotics would shorten and secure the recovery period. It would also allow the basketball player to return to sport quicker that I & D alone. Shrikanth Hegde | Physician | Disclosure: None NIB (National Internet Backbone) | Shimoga, India September 6, 2008 I & D and Culture sensitivity along with oral drugs like cloxacillin is the initial choice in this pt and it may be sufficient ,but he needs close follow up for evidence of bacteremia and MRSA infection enrique kremer | Medical student/physician in training | Disclosure: None Telefonica de Argentina | Neuquen, Argentina September 6, 2008 lesion culture + first generation cephalosporine and then with the results decide the treatment Alison Hannah | Physician | Disclosure: None America Online | Sebastopol, California USA September 6, 2008 Treatment Option 1 would also be perfectly valid and equally likely to produce an acceptable outcome. Salil Gupta Dr | Physician | Disclosure: None Zee Telefilms Ltd | Bangalore, India September 6, 2008 I&D alone may not be sufficient in the patient since MSSA is a possibility which will respond better with antibiotics Janice Taylor | Other health professional | Disclosure: None Comcast Cable | Bellingham, Washington USA September 5, 2008 I&D is critical, with this amount of surrounding cellulitis, anti MRSA treatment is prudent. But I disagree with the choice of antibiotics. Most community acquired MRSA (at least in my community) is also resistant to Diclox and Keflex. My choice is generally Septra, which is usually sufficient. With larger areas of cellulitis, Clindamycin is another choice, but is much more expensive, and for severe cases where the patient has systemic signs, IV Vancomycin and admission is often required. Manish Kak | Physician | Disclosure: None Videsh Sanchar Nigam Ltd - India. | Mumbai, India September 5, 2008 Option 2 is the best one, since there is associated risk of bactremia. clara wekesa | Medical student/physician in training | Disclosure: None Iway network | kampala, Uganda September 5, 2008 Unfortunately I live and work in Africa, where anumber of fascilities are not readily at our disposal,and resistance patterns to particular drugs have not been well studied. I picked option two, because this patient has surrounding skin infection (cellulitis)and having the pus drained will improve the efficacy of the antimicrobial agent. In that case the latter does not have to be given for long periods of time, thus preventing accumulative side effects. Am also in an environment where sterility is in question, so to rely on an incision and drainage alone may not be adequate. steve Rhyan | Other health professional | Disclosure: None Cox Communications | Mission Viejo, California USA September 5, 2008 It may be of interest to "ask" the pt what he "will" comply with? He may be an athlete on scholarship with a "do or die" attitude. Athletes have a large amount of expectation placed on them to perform. And, if he will not play someone else will. With this in the "mix" one might review options with the young man. He did state he "felt" febrile the night before. This may be heading to a systemic effect. Although my clinical experience is only a few years my athletic training background is 20+ and what athletes do is different than "you" may like. I&D is great & may provide a proper "cure",however, an antibiotic like a 1st generation cephalosporin (Keflex) may be benefitial due to staph,strep & e.coli coverage. May not be perfect medicine, but you may only have 1 shot at this young man who "will" be playing to keep his scholarship ride. Jean Paul Vilchez Tschischke | Medical student/physician in training | Disclosure: None Telefonica del Peru | Arequipa, Peru September 5, 2008 I´m a medicine intern in Peru, this patient will benefit the most from the abscess drainage, but with a big area of inflamation, there is a hi possibility of celulitis that needs antibiotic; for me here in Peru, antibiotic for MSSA VALERIA BOSCHETTI | Physician | Disclosure: None COLATINA, Brazil September 5, 2008 drainage is mandatory, and a regimen of an anti-stafilo therapy too Kritapath Tharathornkitti Mr. | Physician | Disclosure: None Chauad, Thailand September 4, 2008 I usually do by this option in my practice, and the result is good without need anti-MRSA therapy Mark D. Sugi | Medical student/physician in training | Disclosure: None University of California, Los Angeles | Los Angeles, California USA September 4, 2008 Without a strong clinical suspicion or results from laboratory cultures suggesting MRSA, the use of first-line antibiotics with good coverage of MSSA and the ß-hemolytic streptococci seems appropriate. In the context of infection by MSSA, the confluence of overprescription of anti-microbial agents for resistant strains of S. aureus with periodic patient non-adherence raises the potential for an increase in the prevalence of resistance and a contemporary diminution in the efficacy of agents to which resistant bacteria are currently susceptible. Milton Carrero | Physician | Disclosure: None Puerto Rico Telephone Company | Mayaguez, Puerto Rico USA September 4, 2008 This is the most cost/effective treatment based in the experience with these infections. eric higgins | Physician | Disclosure: None Bell Nexxia | montreal, Quebec Canada September 4, 2008 Actually, I wouln`t add AB with localized Sx. I would recommend close F-Up (48h) of the pt and initiate AB if no significant change early on during Tx. Jeremy Adams | Medical student/physician in training | Disclosure: None St. Michael's Hospital | Toronto, Ontario Canada September 4, 2008 no good evidence to support empiric MRSA coverage. little downside to covering with anti-MSSA antibiotic. sivaram upadhyaya Dr | Physician | Disclosure: None Cox Communications | New Delhi, India September 4, 2008 The lesion is indurated not fluctuating.If US of lesion reveals underlying pus,ID plus appropriate antibiotics. He has to play a match after a week. Anti biotic like cloxacillin or cephelexin is first choice; ID followed if necessary. Jean Bowyer | Physician | Disclosure: None Safaricom Limited | nairobi, Kenya September 4, 2008 Young man with no risk factors for MRSA DR.SANDEEP DOSHI M.D. | Physician | Disclosure: None | MUMBAI, India September 4, 2008 Incision & drainage with Cephalexin or Cefixime is most likely to yeild a complete satisfactory response. An anti-inflammatory agent could also be added in the first 48 hours of management. Dave Smith MD | Physician | Disclosure: None Social Security Administration | WDM, Iowa USA September 4, 2008 A short course of antibiotics will diminish the pain and hasten healing over I&D alone in this physically active young male. saul weinstein M.D. | Physician | Disclosure: None NewSouth Communications | Jacksonville, Florida USA September 4, 2008 I&D will be incomplete if there is a phlegmon as a component to the purulence. This, plus the fact that there is approx. 5 cm of cellulitis, and the patient is febrile, albeit low grade would lead me to Rx an antibiotic. I would obtain a gram stain and C&S for aerobic and anaerobic bacteria and RX cephalexin. If it turns out to be MRSA, I would switch to the appropriate Abx as identified in the C&S Muhammed Naseem M H | Physician | Disclosure: None Internet Service Provider in Sri Lanka. | Gampola, Sri Lanka September 4, 2008 Incision & drainage with culture and wait for culture report to start any antibiotics. Teodor Todhe | Physician | Disclosure: None ClearBlue Technologies | Hawthorne, New Jersey USA September 4, 2008 I do think that incision and drainage combined with abx is a safe way to go as we are not sure whether an abses has been formed as of yet. Otherwise drainage alone would be enough in this young men with no comorbidities known to sustain these kind of infections. However my main comment was regarding the options to choose as our responses. I did not see a difference between the option 2 and 3 Caron D'Ambruso RN | Other health professional | Disclosure: None Sprint | Pinebluff, North Carolina USA September 4, 2008 I believe this may be hirudintis with MSRA infection. Surgery and drainage should work well in taking care of the hirudinitis and an appropriate antibiotic for the MRSA. Once the lesion is excised, a large opening from removal of the abcess should be treated with iodiform gauze healing the excision site from the inside out without the use of sutures. Radomir Stevanovic MD | Physician | Disclosure: None America Online | Georgetown, Texas USA September 4, 2008 I agree with option #2. It is reasonable to perform an incision and drainage and to start with treatment of MSSA. Should the cultures reveal MRSA, treatemnt can then be appropriately changed Ehsan Chitsaz MD | Physician | Disclosure: None ParsOnline Corp. | Tehran, Iran September 4, 2008 It is evident that there are controversial evidences for the use of antibiotics in soft tissue infections. The characteristics of the lesion represent a furuncle that is in develop to be an abscess. the fact that the lesion does not have any discharge or fluctuation leads to the diagnosis of an immature abscess. Immature abscess means that the organisms are still actively making inflammations and may not yet be limited by the immune system. So, drainage alone cannot be helpful and antibiotics may be of help. Although the incision and drainage is a must for almost all abscesses, the relatively large size of the abscess and the peripheral cellulitis may also be other rationales toward use of antibiotics. John Rose Dr | Physician | Disclosure: None America Online | Headley, England September 4, 2008 I would not incise in the absence of any fluctuation but there is no voting option to allow this view. If there were no abscess, how would incision and 'drainage' help? Many of the treatment options presuppose Staph. aureus infection, but as Dr Moellering (proponent for treatment option 2) points out that, in immune competent hosts, Gp A Streptococci may be the primary infection. The patient may be immune competent, but for 3x5cm of tender erythema, a temp 37.7d C would be unusual. There is already systemic upset...a pulse of 78 cannot be considered normal in a highly trained athlete. I would take a swab for culture and treat with flucloxacillin 500mg four times daily, pending the C&S result and review the wound and temperature/pulse after 48 hrs. He should not be training, nor competing, until temperature and pulse return to his normal. Torben Ek | Physician | Disclosure: None Halmstad, Sweden September 7, 2008 In Sweden the prevalence of MRSA in outpatient populations is very low and therefore unnecessary to cover for initially. The cultures will provide information. Miguel Restrepo | Physician | Disclosure: None Comcast Cable | Fresno, California USA September 4, 2008 When we are giving the incision and drainage only option we are giving the chance to a bacteria most likely Staph infection to become stronger due to persistence of the bacterial multiplication and the potencial disemination through the blood stram. In the I and D plus anti-MRSA option you have already assumed that MRSA is the pathogen and you have lost the opportunity to treat a sensitive staph with the appropiate low spectrum antibiotic creating more chances that the bacteria evolve in the future to create resistence. If the second treatment is given and fails you still have the chance to swith to the MRSA antibiotic and if it worked you have not created any more chances for resistance Josh VonMoss | Medical student/physician in training | Disclosure: None Clearwater, Florida USA September 4, 2008 I would be hesitant to prescribe anti-MRSA drugs without a positive culture for fear of furthering the problem of resistant organisms. However, the size of the erythmatous area does warrant some treatment other than I&D alone, especially given that the patient is unlikely to comply with any orders limiting his activity and is thus likely to aggravate the site. Dr Viraj Rajadhyaksha | Physician | Disclosure: Employee of maker of a related drug or device Warner-Lambert Company | Mumbai, India September 7, 2008 Surgical drainage alone may not be sufficient and treatment with MRSA medications may be unnecessary at this stage. The clinical information does not reveal any suspicion of MRSA. The clinical plan would be as follows: Drainage at the earliest along with antibiotics (Cephalexin preferably) to manage MSSA for a specified duration of time. The safety profile of MSSA agents is quite encouraging and may not be a major issue in this patient. Secondly, we will continue to observe the patient for any suspicion of MRSA both clinically as well as microbiologically(antibiotic susceptibility) If results of any or both of these indicate a MRSA infection, appropriate therapy may be initiated at the earliest. This is based on two important premises: utmost patient care, at the same time preventing unnecessary exposure to agents which may be life saving at some later stage. Anindita Das Dr | Physician | Disclosure: None Telstra Internet | Canberra, Australia September 4, 2008 Incision and drainage is required for complete healing. Ideally, antibiotics should be started only after culture and sensitivity testing. Anti-MRSA therapy should be given only after documented culture of MRSA, unless the patient is at high risk of acquiring CAMRSA. In the absence of culture and sensitivity the best option for treatment is incision and drainage combined with anti-MSSA drugs. Puthanveetil Subhas Dr | Physician | Disclosure: Employee of maker of a related drug or device NIB (National Internet Backbone) | Palghat, Kerala State, India September 4, 2008 I suggest option 2 since only drainage may not prevent systemic spread of the infection and will help resolving the lesion faster Ricardo Guraieb | Physician | Disclosure: None Mexico City, Mexico September 3, 2008 I would favor anti-MSSA therapy because it can be given as an outpatient basis. In case cultures of isolates taken after the incision and drainage show that S. Aureus is MRSA then I could always switch to treatment option 3. So the least agressive and the most reasonable is to initiate Dicloxacillin four times a day, after incission and drainage then follow the patient, 48 hs after incission to see how the cultures and antibiotic sensitivities are going, and then decide to further advance therapy, then the patient must be in-hospital and therapy would have to be against MRSA by intravenous route. Jaime Costa | Physician | Disclosure: None NET Serviços de Comunicação S.A. | São Paulo, Brazil September 3, 2008 I agree with Dr. Robert Moellering, mainly to prevent further spread of the infection and bacteremia. Jim Richards PhD | Other | Disclosure: None Charter Cable/Monterey Park LAN | Sudbury, Massachusetts USA September 4, 2008 Ball player has been in many geographically distinct places. The probability of a CA-MRSA may be higher than typical for the home base incidence. Have the student check his temperature over the next 5 days and if elevated go to the hospital for more aggressive therapy. francisca s | Physician | Disclosure: None stgo, Chile September 3, 2008 I would give this young man antibiotic and hot compresses on the first day and the day after I will drainage the abcess. If I do the surgery first, It will not be succesfull because the skin is firm. I always use antibiotics before and after the drainage and specially in this case because the patient has fever Treatment Option 1 Comments Treatment Option 2 Comments Treatment Option 3 Comments Treatment Option 3: Incision and drainage plus anti-MRSA therapy. 146 Readersʼ Comments Ramesh Nathan | Physician | Disclosure: None Thousand Oaks, California USA September 21, 2008 Probability of CA-MRSA is overall much higher and clinical experience has led me to believe that surrounding cellulitis of 5 or more cm will respond better to I&D plus antibiotics active against CA-MRSA David Stewart, PharmD | Other health professional | Disclosure: None East Tennessee State University | Johnson City, Tennessee USA September 19, 2008 This patient is an athlete and at higher risk for CA-MRSA than the average individual. I have seen too many patients return with worsening infection from both I&D alone and oral antibiotics alone. Depending on severity of lesion, antimicrobials could include IV vancomycin followed by oral agents or oral agents, but in either case, the lesion should be I&D. Don't forget about inducible resistance to clindamycin (D-test). In our region, clindaymycin is not a good empiric choice because most isolates are D-test positive. Susan Pandya | Physician | Disclosure: None Longwood Medical Area | Boston, Massachusetts USA September 18, 2008 Agree that management of an uncomplicated abscess first requires an incision and drainage. There is minor amount of surrounding cellulitis and the location of the abscess would make continued draining slightly more difficult. I would add antimicrobial coverage and culture the specimen. In a 20yr old male athlete in contact with multiple other players and contacts in the locker room, coverage for methicillen resistant staph aureus (MRSA) would be adviseable given the increased incidence of community acquired MRSA and its tragic consequences. Octavio Saenz | Physician | Disclosure: None Albuquerque, New Mexico USA September 18, 2008 The patient "believes he may have had a low-grade fever the night before but did not take his temperature" is an important piece in this history, which tips the scale toward antibiotic therapy. He is a young athlete who travelled throughout the U.S. where prevalence of MRSA is high, and his lesion is 5cm in size within 48 hours. All indications to be aggressive in your treatment. Mike Mallin | Physician | Disclosure: None Intermountain Health Care | Salt Lake City, Utah USA September 22, 2008 There is yet no good data supporting incision and drainage alone in suspected simple MRSA cutaneous abscesses. In this new era of MRSA, a more virulent bug, I support abx coverage untill more research is performed. David Allain David | Other | Disclosure: None Louisiana State University | Mobile, Alabama USA September 22, 2008 Now before we justify this treatment we should remember that MRSA is the result of the abuse of antibiotics. Since Staph skin infections, including MRSA, generally start as what has been described in our case an this patient is an athlete spending hours on end, in a setting where community MRSA is most definitely present. These can quickly turn into deep, painful abscesses that require surgical draining, but luckily our patient is very aware of his body and came in within two days from recognition. Since MRSA can also penetrate into the body, causing potentially life-threatening infections throughout, the most responsible treatment for a patient this age is to take every precaution and prevent the spread of MRSA to his fellow teammates. Ricardo Lemos | Physician | Disclosure: None Verizon Internet Services | Bryan, Texas USA September 22, 2008 The third option is the only addressing the problem of recurrence. If that is not addressed, both intrafamilial spread as well as recurrences are possible if not likely. Physical risk factors that led to the initial abscess need to be addressed (shaving, injury, tight fitting garments, etc) Poornima Padellapalli Dr | Physician | Disclosure: None Comcast Cable | Great falls, Virginia USA September 22, 2008 The lesion is not fluctuating.If usg reveals an absess I&D is a better choice.If the absess is small aspiration and culture is a better choice. Pending culture report anti MRSA tretment is better option as he has to play a match after a week. Dr. Abrar Ali Katpar | Physician | Disclosure: None Hail, Saudi Arabia September 22, 2008 Don't leave any chance to put patient in trouble or wait for the c/s results.Your Patient needs full cover. Do as best GP can do and make him well in comming week for the games. David Dickensheets | Physician | Disclosure: None Comcast Cable | roswell, Georgia USA September 22, 2008 based on experience as a community ID doc, seeing easily 2 or 3 cases of this a week, there is no question in my mind that aggressive therapy is needed. Richard Lari | Physician | Disclosure: None PeaceHealth | Eugene, Oregon USA September 21, 2008 The arguments presented by the expert in option 3 are compelling and well referenced. Although its hard to tell just from the picture, the description seems to indicate that there is significant surrounding cellulitis in addition to the abcess - given that, I think it would be hard to not give this patient antibiotics. While I don't think "defensive medicine" should be a significant driver of medical decisions, awareness of medicolegal issues is a fact of life. How would a physician be able to defend him/herself if this patient who appears to have a cellulitis in association with this abcess was not given antibiotics and then developed a significant complication e.g. severe sepsis. David Mandelblum | Physician | Disclosure: None Comcast Cable | Sarasota, Florida USA September 21, 2008 PT,physical findings , and his expossure to MRSA, support 3 option treatmen dick goldstein md | Physician | Disclosure: None harvey cedars, New Jersey USA September 21, 2008 think this is best option for earliest resolution Panagiotis Renieris Dr | Medical student/physician in training | Disclosure: None ADSL users of | Athens, Greece September 21, 2008 Low grade fever may be concidered a sign of systemic reaction to local inflammation, so antibiotic use would be a reasonable choice given the immaturity of the abscess. Community prevalence is high enough to support the use of anti-MRSA ABs. I would also suggest physical exam for a fistula by use of syringe and plastic IV line tube given the patient's age to exclude fistula creating underlying cause (such as CD), but no further workup. Dr. Mukund kakade Doc | Medical student/physician in training | Disclosure: None MTNL CAT B ISP | Mumbai, India September 21, 2008 The most appropriate therapy with proper use of antibiotics Norris Payne MD | Physician | Disclosure: None Houston, Texas USA September 20, 2008 Here in Houston, TX, as a child and adolescent physician, we see this at least twice a week and have for years. Bactrim is the only drug that works consistently for MRSA, ollowed closely by Clindamycin. Other PO meds nearly always fail. I&D is almost as important as the antibiotic and in fact the antibiotic may not work at all without appropriate drainage of abscess. Cheri Sandberg FNP | Other health professional | Disclosure: None EarthLink | San Anselmo, California USA September 20, 2008 I would certainly culture the wound, but if this young man were in this area I'd certainly start him on anti-MRSA meds and teach him about how to stop the spread amongst his teammates. I've seen this stuff spread through a group of students in close confinement, and it's not pretty. If he's positive for MRSA, I like to use bactroban ointment nasally in patient and housemates, too. Howard Lyon | Physician | Disclosure: None ScrippsHealth | San Diego, California USA September 19, 2008 Although option one cites literature from the 1950s suggesting surgical drainage alone to be definitive treatment, the emergence of community acquired MRSA renders these conclusions invalid. In clinical practice I agree with the study quoted in option 3, that there is a high rate of recurrence in MRSA mediated STI treated with surgery alone. I would therefore give adjunctive antibiotic treatment after I and D. Steven Miller | Physician | Disclosure: None SBC Internet Services | Chicago, Illinois USA September 19, 2008 Why does an athlete get an abscess in the buttock? Possibly injecting something he shouldn't. Higher risk for MRSA in this situation. Rick Blume | Other health professional | Disclosure: None Verizon Internet Services | Boston, Massachusetts USA September 18, 2008 It is surprising that none of the others elect to test for MRSA with the reletively new GeneOhm/BD quick sensitive test for MRSA. Facilitating appropriate drainage and treating for MRSA seems appropriate given the case as presented. ABDERRAZAK MAGHEZZI | Physician | Disclosure: None Jetmultimedia Hosting | BESANCON, France September 18, 2008 I agree with the treatment with drainage and antibiotherapy Leonard Johnson | Physician | Disclosure: Financial tie to maker of a related drug or device ST. JOHN HEALTH SYSTEM | Detroit, Michigan USA September 18, 2008 As 70% of patients presenting with this clinical syndrome will have MRSA infection, treatment for MSSA achieves little. The question of whether active therapy is needed vs. I&D alone was addressed by Ruhe et al (Clin Infect Dis, 2007). They found a 13% vs. 5% rate of treatment failure in those receiving inactive vs. active therapy (OR 2.82). Oliver Torrefranca M.D. | Physician | Disclosure: None British Telecommunications | Coventry, England September 18, 2008 All treatment Options are universallly acceptable paths to go, especially Option 1 which proved successful in some of my patients but NOT those patients with active exposure i.e. contact sports with epidemical concerns, but Option 3 offers quicker fix and can safely discharge the patient to engage in their sport of interest. Maurice Carter M.D. | Physician | Disclosure: None Verizon | New York, New York USA September 18, 2008 There is a considerable risk that the athlete mightbe in a position to pass his infection to team mates and others in the locker room. Aggresive treatment seems to be indicated for rapid resolution and eradication of a serious infectious agent. Fel Stancioiu | Other health professional | Disclosure: Employee of maker of a related drug or device Jump Network Services S.R.L. | Bucharest, Romania September 18, 2008 Incision and drainage plus wound "toilet" with clorhexidine plus topical antibiotic on the edges of the wound (on skin; neosporin may be fine) may be a good option. A systemic Abx for the localized infection in a immunocompetent patient without antibiogram may be too nonspecific (perhaps with the exception of azythromycin, which gets concentrated preferentially in the infected tissue). The size of the infected tissue and the rapid spreading indicates that local defenses are overwhelmed and some local antibacterial intervention is needed to stop the infectious process and promote healing. Muhammad Khurram Shahzad | Other health professional | Disclosure: None Dancom OnLine Services (Pvt.) Ltd. | Lahore, Pakistan September 18, 2008 As there is fever also so the first treatment will not work efficiently, mostly in such cases isolation of MRSA had been observed so 3rd option is the best of as a treatment. Yasmin Hamirani | Medical student/physician in training | Disclosure: None Road Runner | Torrance, California USA September 18, 2008 I would do Incision and drainage if there is an abcess. Certainly there is cellulitis but he does not seem to be bacteremic. Location is vulnerable in this athlete and community acquired MRSA is quite common in US. Keeping all this in front, I would treat emperically with Anti-MRSA and follow up with him in few days. Abigail Martinez Abigail | Physician | Disclosure: None Chicago, Illinois USA September 18, 2008 I don't always have the opportunity to see patients for follow up, my patients have poor access to medical care, and I see multiple cases of complicated MRSA abscess and cellulitis on a daily basis. Hence, I would prefer to I+D as well as use antibiotics from the onset. Lee Bowman | Other health professional | Disclosure: None Cox Communications | Phoenix, Arizona USA September 18, 2008 Why not cover all bases. Given his possible exposure to the organism in locker rooms, I feel it is the viable alternative. That said, I could be wrong. Daniel Allan MD | Physician | Disclosure: None TULAROSA COMMUNICATIONS | Las Cruces, New Mexico USA September 18, 2008 Many pts. with MRSA are afebrile. In our community, MRSA is so prevalent that the assumption is warranted until cultures prove otherwise. William DeMedio | Physician | Disclosure: None D&E Communications | Lancaster, Pennsylvania USA September 18, 2008 I vote for the safest option. If it were my son, I would take this approach. I also have my own anecdotal evidence to back up my comments. Edwin Serrano | Physician | Disclosure: None Mexico City, Mexico September 18, 2008 In my daily practice with children, I prefer to initiate a course of treatment with antibiotics specially for MRSA (ie dicloxacillin 25-50 mg kg day qid) at least 7 days prior consideration of drainage according to evolution, and most patients do not actually need drainage, leaving no added scars or lacerated tissue due incisions, prolonging antibiotics to 14 or 21 days as necesary. eric jackson | Physician | Disclosure: None Optimum Online (Cablevision Systems) | north arlington, New Jersey USA September 18, 2008 with such significant surrounding cellulitis, i would also treat him post i&D with oral antibiotic therapy. since there is a large incidence of mrsa in outpatients in my area, i would add therapy for mrsa. John Morrison | Physician | Disclosure: None SBC Internet Services | Carmel, California USA September 18, 2008 The history of athletic activity and the probability of MRSA persuades me to select Option 3. Doug Skura MD | Physician | Disclosure: None Marysville, Ohio USA September 18, 2008 I have come in as a surgeon to help the care of patients who have had their infection get "away" from the other treating doctor with usually the ineffective MSSA antibiotic tried first with or without the necessary I&D. This lesion for this case is so much more likely to be MRSA related that tetracycline or Bactrim po should be started along with the absolutely necessary I&D with removal of the necrotic tissue. I believe the antibiotic will reduce the chance of the lesion becoming more "rodent-like" and help to prevent less tissue loss. Admission for IV Vanco for larger or more "angry" lesions should have a low threshold to reduce systemic and local effects of the infection. Rest, soaks and cleansing still go a long way to help ease these infections.It remains to see if the use of antibiotics and Chlorhexidene scrubs will reduce the colonization or infection of other close / intimate contacts with MRSA as one couple I helped gave it back and forth until both got treated. Carrie Perez | Other health professional | Disclosure: None Level 3 Communications | Dade City, Florida USA September 18, 2008 Yes, Anti-MRSA therapy is a good idea but should never include antibiotics unless cellulitis and/or fever presents. However, I urge all physicians/surgeons/students to investigate Dr. Cutler's (University of East London) stabalized allicin therapy as a preventative and treatment for CA-MRSA and HA-MRSA. It is taken orallly and also used topically without the risk of mutation. Jose Stoute | Physician | Disclosure: None Comcast Cable | Hershey, Pennsylvania USA September 18, 2008 I feel that with this large abscess and the amount of cellulitis present a short course of antibiotics following incision and drainage is prudent to prevent further spread of cellulitis and bacteremia. I argue also that a temperature of 37.7oC is elevated. Bernard Boutet | Physician | Disclosure: None IOSCO | Quebec city, Quebec Canada September 18, 2008 MRSA must always, in my opinion, be considered in such a clinical setting; meanwhile, this lesion must be surgically addressed by incision and drainage. Dawn Pirri | Other health professional | Disclosure: None America Online | Fairfield, Maine USA September 18, 2008 I am in favor of incision and drainage plus anti-MRSA therapy. MRSA is so easily transmitted with atheletes, locker rooms and equipment. The benefit of antibiotics will certainly be wise and a culture can be done to confirm the results. The betadine wash is also a wise decision to keep the bacteria at bay, especially while using restroom facilities. MaryMargaret Breed, RN RN | Other health professional | Disclosure: None Randolph, Vermont USA September 18, 2008 I&D plus 2% chlorhexidine for daily bathing and C&S, and instructions to call back in two days after I&D to report on trends, plus questioning on history of activities that could have led to this infection. Also instruct to maintain strict personal hygiene including frequent handwashing and clean gauze 4 x 4's to absorb drainage, and at least daily change of cotton brief. After two days, unless healing rapidly, prescribe antibiotic appropriate to C&S results, plus followup. A young athlete has every opportunity to spread this rather nasty infection on his or her buttock to others and/or to other areas of his or her own skin. Should not be taken lightly, regardless of any literature favoring I&D only. Christina Panait | Other health professional | Disclosure: None Videotron Ltee | Gatineau, Quebec Canada September 18, 2008 In my oppinion (as a RN student) I would say that the young athlete which travel a lot, lots of citys lot of peoples + the signs of cellulitis he has to be drained, and preventive anti MRSA therapy, as well should be better to have as well a sample for culture. Glen Tamura | Physician | Disclosure: None Children's Hospital | Seattle, Washington USA September 18, 2008 All of these three are reasonable options. Local epidemiology is critical in the decision-making. In some regions, including where I practice, the vast majority of these abscesses grow MRSA, so options 1 and 3 make the most sense, as option 2 is likely to lead to side effects without benefit. On the other hand, if MRSA is less prevalent, option 2 is reasonable. It is important to use a brief course of antibiotics to minimize side effects. Claire Richardson | Other health professional | Disclosure: None Evergreen Medical Group | Seattle, Washington USA September 18, 2008 Virtually every athlete who showers, changes clothes in a common shared area, has physical contact with other athletes of other facilities, or goes to other facilities and showers, etc, can unknowingly, at any time, come into contact with mrsa. One cannot assume based on one person's hygiene/appearance that contact wasn't/isn't possible. In some cases the athlete may not be allowed to participate in certain sports until the lesion/abscess is resolved to protect both the athlete and whoever, or whatever(equipment)from coming in contact with any wound or drainage regardless of bandaging. MUHAIRWE Ninsiima | Medical student/physician in training | Disclosure: None Afsat Communications Ltd | Gulu University, Uganda September 18, 2008 i think antibiotic therapy secondary to incision and drainage will do for this patient, and we'll avoid bacteria spreading to another region Erin Schaaf PharmD | Other health professional | Disclosure: None Community Hospitals, Indianapolis | Westfield, Indiana USA September 18, 2008 I & D could work but we don't know at this time if there is anything to drain. Also, I've seen many patients who have experienced clearing of presumed "CA-MRSA" bumps on the skin with mupirocin only to have multiple bumps appear elsewhere. Also, the followup can be terrible in regard to patients that only receive I & D and fail this therapy. So, many others could be exposed, infected, and who knows at this point the innoculum needed to cause necrotizing CA-MRSA pneumonia. It is better to be proactive. John Crane | Physician | Disclosure: None State University of New York at Buffalo | Buffalo, New York USA September 18, 2008 Many of our surgical colleagues are not doing Option 1, 2, or 3, but instead admitting such patients to the hospital for I.V. vancomycin for 7- 10 days, sometimes sending patients home on home I.V. vanco. I do not agree with the latter approach and hope some expert will say so. franck tirgari Dr. | Physician | Disclosure: None Mid-Hudson Cablevision, Inc. Catskill | HUdson, New York USA September 18, 2008 I work in Hudson as a hospitalist and we have a big jail population, often they come with a blister and in 90% of the time it's MRSA,we drain the abscess and always put them on antibiotics. ana leon | Physician | Disclosure: None miami, Florida USA September 16, 2008 due to the high incidence of community acquired MRSA, specially among this group of patients, we should alwais covered for this organism under this circumstances. DEEPA SHAH | Physician | Disclosure: None New York, New York USA September 18, 2008 We have noted an increase in "sexually transmitted MRSA" in community. This is skin to skin transfer of MRSA, which responds well to oral treatment. So it will be prudent to add MRSA coverage in addition to I and D. As high as 70% of the skin and subcutaneous infections in community setting can be due to MRSA according recent data from ER studies. pooneh badre | Physician | Disclosure: None St. Mary's Hospital | waterbury,ct, Connecticut USA September 12, 2008 Drainage will be essential ,however due to prevalence of MRSA in my area and eagerness of patient to be treated before next basketball game should be place don MRSA coverage . eric carter | Other health professional | Disclosure: None Road Runner Business | wilmington, North Carolina USA September 12, 2008 There is no telling where he has been sitting / who sat there before him. Have seen the complications of I&D / culture only of community mrsa. The problem of treatment failure (I&D only) if comm mrsa suspected is sometimes severe (hospitalization / death). Large practice and frequently see community mrsa abscess as well as carriage. Go Yoshida | Medical student/physician in training | Disclosure: None Japan Communication Inc. | Tokyo, Japan September 12, 2008 Skin inflammatory lesions should be aggressively treated by means of incision and drainage. The exception is a furuncle in the face, since incision may let bacteria into sinus cavernosus. The presented image shows redness, edema and swelling, which suggests it also pulsating pain. The question is whether or not the responsible bacteria have resistance to controversial antibiotics. However, there is more reason to justify the administration of antibiotics plus incision and drainage. Toxic shock-like syndrome is rarely seen, but once this happens, DIC and multi-organ failure lead the boy to lethal conditions. The empirical administration should be needed when considering the potential case. Zain Chagla | Medical student/physician in training | Disclosure: None UUNET Technologies | Kingston, Ontario Canada September 12, 2008 In the context of organized sports in the United States, CA-MRSA has become an appreciable entity requiring empiracle treatment brian hung dr. | Physician | Disclosure: None CHTD, Chunghwa Telecom Co., Ltd. | chutung, Taiwan September 12, 2008 Nowaday, overutilization of antimicrobial agents in our daily practice in almost every field of medicine has resulted in lots of resistant strains such as MRSA and without aggressive management after surgical I&D sometime may end up with undesirable outcome and serious consequences. Therefore,it is reasonable to use agents against MRSA until it will be proved otherwise. MARCELO MIMICA MD | Physician | Disclosure: None SÃO PAULO, Brazil September 18, 2008 Given the prevalence of CA-MRSA in the US, and the possibility of associated celulitis and also metastatic infection, the safest option is drainage plus anti-MRSA therapy. In addition, the use of antimicrobial therapy in these cases could decrease the transmission rate. Edgar Murguia MD | Physician | Disclosure: None CABLEVISION SA DE CV | Mexico City, Mexico September 12, 2008 The patients primary concern strongly advices to administer antibiotics and the activity he's involved in suggests anti-MRSA, as the most accurate choice. Margaret Paredez MD | Physician | Disclosure: None Solana Beach, California USA September 12, 2008 No. 3 brings up a point that like in our community, you assume MRSA until proven otherwise. We would consider I.V. (parenteral) antibiotics if cellulitis increases in a 12 hour period and use Vancomycin. Most of us are I&D first, then add oral doxycycline or bactrim + cephalexin and await cultures. We do frequent rechecks at our ER and often repeat Vacomycin doses in a 24 hour period. We all become frustrated if we feel we need frequent repeat vacomycin doses to get a cellulitis but often after ID and orals, there is minimal improvement. David Webb | Physician | Disclosure: None Department of Veterans Affairs | Long Beach, California USA September 12, 2008 Would like to know if each of the authors really advocates their position or if they were asked to defend the position only in the spirit of a debate. Lanny Copeland MD | Physician | Disclosure: None Columbia Health Care | Brentwood, Tennessee USA September 12, 2008 MRSA is a community acquired infection now; I&D pluse anti MRSA antibiotic would be indicated Leah Amir MS, MHA | Other health professional | Disclosure: None CHARTER COMMUNICATIONS | St. Louis, Missouri USA September 12, 2008 The patient should be screened for MRSA or community acquired MRSA. Given his overall health, one should consider any underlying health status, ie. diabetic or poor insulin / sugar metabolism as well as verify he has sufficient protein to aid his immune system. There is a reason the abcess was caused and is not progressing toward healing. Once any underlying causes are ruled out or identified and corrected, the patient should begin treatment with sharp debridement, followed by a dressing. Once results are received (24hours) regarding the bacterial flora, such as Strep or Staph each of which prevent healing in a different manner, he may be followed by appropriate antibiotic therapy. Testing for various strains of Strep or Staph would be prudent and then focus the antibiotic therapy accordingly. Follow up with the patient in 3 days after antibiotic adminstraiton and dressing of the abcess to check for improvement. Deepa Patel RN, BSN, CCRN | Other health professional | Disclosure: None Lewisville, Texas USA September 12, 2008 These is a classic presentation of a MRSA infecion. His risk factors would support MRSA as well(amoxcillin use, basketball player, played at various universities, low grade fever etc). MRSA is all over the news about its rise in the community as well. TWU NP student. Diljit Karayil | Physician | Disclosure: None Cherry Street Health Services | Grand Rapids, Michigan USA September 12, 2008 In my practice i have seen better results with I&D and sending the swab for culture and also a nasal swab along with antibiotics.I&D alone does not help a lot of patients. MRSA is very dominant in the community i practice and commonly seen in inmates,shelter and college sport teams.I do agree with being vigilant if other team personnels presenting with the same symptoms. Maximino Bello | Physician | Disclosure: None BROADBAND PHILIPPINES | Manila, Philippines September 12, 2008 The lession is large. I and D alone is insufficient. Taking in account the patients profile and his desire of rapid resolution of the problem anti-MRSA is appropriate William L Hoppes MD | Physician | Disclosure: None Canton, Ohio USA September 12, 2008 The size of the area of cellulitis (5 cm) makes me want to use antibiotics. The likelihood of CA-MRSA, the possibility of PVL, and the frequency of occurrence and recurrence of MRSA in athletes (we have had several outbreaks in OHIO)leads me to Rx for MRSA with Clindamycin or TMP/SMX. jorge gentile Dr | Physician | Disclosure: None Telefonica de Argentina | Tandil, Argentina September 12, 2008 This patient need resolve his problem quikly , and the option that covers the different posibilities is the 3. We are seeing a growing number of skin and soft tissue infection secondary to MRSA , and there is not clear evidence to help clinicians in his/her decitions. Moises Auron MD FAAP | Physician | Disclosure: None Cleveland Clinic Foundation | Cleveland, Ohio USA September 12, 2008 The treatment of choice for an abscess is just plain Incision and drainage; however, there is an increasing prevalence of community acquired MRSA - this occurs in the multiple settings (athletes, public baths and pools, tattoo and piercing parlors, etc). The wound should be cultured after performing an adequate incision and drainage - which would guide further therapy. In light of this player most likely behavior - which will be to go an play as soon as he can; the safest choice in order to provide a faster resolution of the abscess as well as minimize the spread of MRSA - would be to treat it with oral antibiotics (co-trimoxazole or clindamycin) with clinical followup and medical clearance before he returns to the game. Tayo O | Other health professional | Disclosure: None Boston University | Boston, Massachusetts USA September 12, 2008 Having seen this several times in many of the young adults presenting to the hospital (Boston area), I have to say that though I agree that Incision and drainage (cold blue steel) is essential, I would advocate for adjunctive treatment with bactrim or clindamycin (dosed appropriately) SUDERSHAN ADMAL | Physician | Disclosure: None Department of Veterans Affairs | ALEXANDRIA, Louisiana USA September 12, 2008 WE ARE TREATING MANY SUCH INFECTION IN ED AND AMBULATORY CARE SETTINGS.ANTIBIOTICS GIVEN WHEN POSITIVE FOR MRSA. Devapiran Jaishankar | Physician | Disclosure: None AreaNet | Johnson City, Tennessee USA September 12, 2008 Extensive evidence of recurrent MRSA infection noted in practice Nicola di Meo MD | Medical student/physician in training | Disclosure: None Trieste, Italy September 16, 2008 Community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA) infection has become common worldwide. Skin and soft-tissue infections (SSTIs) are the most frequent forms of the disease. Many studies show a significant and ongoing increase in the incidence of MRSA in patients with SSTIs. Therefore, if a young and healthy patient comes in with a skin and soft tissue infection that forms an abscess, it is necessary to have CA-MRSA as part of differential about the etiological causes of that infection. Obtainment of culture specimens is important for documentation of the presence of MRSA and for susceptibility testing to guide therapy. Purulent lesions should be incised and drained and an empiric coverage with an MRSA antimicrobial should be used as first-line therapy in order to avoid local and systemic relapses. Kurt Wargo | Other health professional | Disclosure: None Tuskegee University | Huntsville, Alabama USA September 12, 2008 As a clinical pharmacist who sees these infections on a daily basis, I can say, in my patient population I would opt to I&D and treat this as MRSA until proven otherwise. This wound clearly has an area of induration surrounded by erythema...HIGHLY indicative of Staphylococcus aureus. In 2008, one must rule out MRSA until you prove it is not. In addition, because of the high virulence of community-acquired MRSA, one must consider antibiotic therapy in addition to simple I&D, to prevent the spread and toxin production. Our typical treatment regimen would include a combination of Vancomycin and Clindamycin in order to acheive "The Eagle Effect." Ivan Vucina | Physician | Disclosure: None Antofagasta, Chile September 12, 2008 I think that this young basket-ball player, was playing basket-ball throug many places in USA, has high possibilities that his skin lession could be produced by Staph. Aureus Meticillin-resistant.With Antibiotics, we can eliminate a focus and potential transmission to others players or persons richard garceau | Physician | Disclosure: None Stentor National Integrated Communications Network | dieppe, New Brunswick Canada September 12, 2008 Altough drainage was proven sufficient to clear such an infection, I fell uncomfortable not to prescribe a systemic antimicrobial. Due to participation in contact sports, the patient has a very significant risk of MRSA cutaneous abscess. I would prescribe Septra Roger Alvarez OMS-IV | Medical student/physician in training | Disclosure: None The Johns Hopkins Medical Institutions | Davie, Florida USA September 12, 2008 CA-MRSA is now the most frequently cultured organism in skin and soft tissue infections presenting to Emergency Departments in the US. CA-MRSA may present without discernible risk factors. While it is likely that the patient's infection will respond well to simple incision and drainage, adding an anti-MRSA antibiotic increases the likelihood of cure. One option not listed but frequently encountered in the ambulatory setting (namely, prescribing an oral antibiotic without I&D) must be avoided. Physicians may be reluctant to perform incision and drainage in an office setting, and reluctant to refer a patient to a surgeon with an uncertain diagnosis. The surrounding area of cellulitis may lead some physicians to lean towards a diagnosis of cellulitis and prescribe cephalexin. In my experience with various preceptors, I have noticed that bias in the ambulatory setting, and I have frequently seen such patients return with obvious fluctuance, new drainage, and systemic symptoms. Instead, this patient deserves incision and drainage with additional coverage by an anti-CA-MRSA antibiotic, such as trimethoprim sulfamethoxazole. Janet WIlson | Other health professional | Disclosure: None TDS TELECOM | Lavergne, Tennessee USA September 8, 2008 I see many of these in my practice and usually find that MRSA is tx best with anitbiotics and I&D Denis Rodriguez | Physician | Disclosure: None Telefonica del Peru | Lima, Peru September 8, 2008 The anti-MRSA therapy seems to be the most clinically correct guess after reading patient's history. Jabu Mbokazi Dr | Physician | Disclosure: None Medical University of South Africa | Polokwane, South Africa September 8, 2008 Incision and drainage alone will not take care of possible new eruption of abcesses at other sites. Combining I&D with anti-MRSA treatment will ensure that bacteria lurking elsewhere will be taken care of. In an athlete playing contact sport MRSA infection is the most likely offending organism. Ronald Angoff MD | Physician | Disclosure: None New Haven, Connecticut USA September 12, 2008 There is approximately 30% MRSA in our community. Most of similar lesions have proved sensitive to sulfatrim in our experience, so we have chosen this oral antibiotic pending culture results. Rahulkumar Singh MD | Medical student/physician in training | Disclosure: None Comcast Cable | Baltimore, Maryland USA September 8, 2008 I think MRSA treatment start once patient comes to Hospital even before culture is back in most of case as the incidence of MRSA is very high in US now.As an Intern in community hospital when i get a patient with abcess most of the time i try covering MRSA. I have seen patients recovering very well post I $ D with MRSA antibiotic coverage Miluy Guerrero Mario | Physician | Disclosure: None Ya.com Internet Factory | Lorca, Spain September 7, 2008 big abscess, in a player risk for MRSA, rapidly evolving Brenda Gumz | Medical student/physician in training | Disclosure: None Sao Paulo, Brazil September 8, 2008 This patient give us only one chance to be cured: in one week, he needs to be 100% performed for his competition. So, we can't drain his abscesse and watch carefully, waiting for a fever to start an oral therapy. So, knowing the prevalence of MRSA S. aureus in USA comunity, I would associate anti-MRSA therapy plus I&D as frontline therapy. In Brazil, MSSA S. aureus are prevalent and I would choose anti-MSSA therapy. Crystal Cardwell | Medical student/physician in training | Disclosure: None Fargo, North Dakota USA September 7, 2008 I have trained in numerous hospitals across the United States and the pattern that I found is the following. MRSA was prevalent in every age range,ethnicity, sex, and health status. Young children, adolescents, and young adults, who did not have any health problems, nor were in an environment of illness, come up positive for MRSA. So the hospitals started to put any one who had a draining abscess or cellulitis on contact precaution. I thought that when I moved to North Dakota, in a city that was spread out and deemed the cleanest according to the EPA, that I would experience a decreased incidence and resume the typical presentation of MRSA infected individuals. This was not the case. Again, the same pattern was surfacing. So this is why I feel that prophylactic treatment of MRSA is a good choice for soft tissue or draining abscesses. If we do not stop MRSA it will continue to spread at a high rate. Arvinder Singh (Ipoh) Mr. | Medical student/physician in training | Disclosure: None TMnet TELEKOM MALAYSIA, | AIMST University, Malaysia September 7, 2008 I agree with treatment option 3. Yes, we have to indeed think of MRSA due to significant abuse and misuse of Abx in today's world of medicine. Treatment 3 offers the best option of taking a culture&sensitivity, performing an I&D as well as covering antibiotics. Had this case presented 5 years ago- probably the diagnosis of MRSA would have been a last option diagnosis. I would also like to state that we even consider VRSA here, as the option said that it should be made based on incidence in the area of residence. Since the recent availability of Vancomycin as an over-the-counter drug from pharmacies in certain countries, it shouldn’t be ruled out. Another ddx which I may like to add if there is re-occurrence of the problem is a diagnosis of gluteal hernia (enterocele type)- it can present with purulent pus in the gluteal region. Maybe percussion and an X-ray should be done to rule that out as well. Kevin Kon, PA-C PA-C | Other health professional | Disclosure: None TCSN Internet | Peoria, Arizona USA September 7, 2008 All the treatments are valid. I agree with the 3rd choice but before I/D an indurated infectious process I would needle asperate or perform an US to verify purulent matter. Most indurated lesion will yeild no purulent d/c. Peggy Gildersleeve | Other health professional | Disclosure: None RCN Corporation | Lexington, Massachusetts USA September 7, 2008 Just curious, is he a D1 athlete? Regardless, I'd select Treatment Option #3. Satish Madiraju | Physician | Disclosure: None ST. VINCENT HOSPITAL | Worcester, Massachusetts USA September 7, 2008 In this patient with significant surrounding area of cellulitis, empiric antibiotic therapy with an agent active against community acquired MRSA strains is a prudent course of action in addition to Incision and Drainage of the abscess. John Paul Schwartz D.O. | Physician | Disclosure: None CACTUS HEALTH SERVICES-060118042012 | Sanderson, Texas USA September 6, 2008 In far West Texas MRSA is the primary infection due to the high prevalence of this organism in rural prison populations that spread to the community. Antibiotics are essential, even after I and D of the lesion. I don't like this approach, but the spread is so rampant here. Thomas Russo | Physician | Disclosure: None State University of New York at Buffalo | Buffalo, New York USA September 6, 2008 Besides potentially enhancing resolution of the local infection, antimicrobial treatment in addition to I&D will preemptively treat possible metastatic infection. This complication is always a concern when dealing with probable S. aureus infection. Although this is an uncommon complication; infection of bone, heart valves and/or the epidural space with S. aureus can be catastrophic. Therefore, this is clearly a setting where one should be conservative. Further, treatment choices such as TMP-sulfa, doxycycline and clindamycin are inexpensive and reasonably well tolerated. Kathy Thomas | Other health professional | Disclosure: None FARRIS CHRYLSER DODGE JEEP | Raleigh, North Carolina USA September 5, 2008 Working in at a homeless clinic located in a homeless shelter I have seen the best results with I & D plus anti-MRSA therapy. Those treated without antibiotics were more likely to return with re-infection. Alisa Baer | Physician | Disclosure: None University of Pennsylvania | Philadelphia, Pennsylvania USA September 5, 2008 If he presented to his primary care physician's office I would be inclined to just do I&D as I would feel more comfortable about his follow-up - but in an ER setting I am not sure if he will follow-up if it gets worse, and am more likely to treat with an antibiotic in addition to I&D Michael Sinclair | Physician | Disclosure: None America Online | Allentown, Pennsylvania USA September 5, 2008 options two and three were the same==the right choice is antibiotics alone Bryan Cole Smith Ed. M. | Other | Disclosure: None America Online | Wenonah, New Jersey USA September 5, 2008 As a layperson who has personally experienced MRSA, I was rather surprised that not one of the three options took into consideration the fact that the patient did not like to take medications! Listen to your patients and prescribe accordingly. Carl Sufit | Physician | Disclosure: None SBC Internet Services | Modesto, California USA September 4, 2008 Our urgent care is seeing about 3-4x the number of cutaneous abscesses as 5 years ago. ~70% are MRSA. We see many patients with recurrences, multiple family members, school athletes, etc. I am aware of studies suggesting antibiotics aren't helpful but I wouldn't feel comfortable not treating with them; if it were me or a family member, I'd take them. CESAR CRUZ | Physician | Disclosure: Employee of maker of a related drug or device Baxter Healthcare Corporation | BOGOTA, Colombia September 4, 2008 MRSA risk is big across the USA, and dont forget about the chance colonization issue in this patient R. Doug Hardy, MD MD | Physician | Disclosure: None University of Texas | Dallas, Texas USA September 7, 2008 I would perform adequate incision and drainage and then treat with doxycyline. Although I was the principle investigator and senior author for the Lee et al. paper referenced in the case study, I would still use anti-MRSA therapy. Currently, my group is conducting a prospective, randomized trial of SSTI incision and drainage with or without anti-MRSA therapy to help answer this question. Prospective randomized data shows doxycycline to be effective in this type of patient and probably superior to trimethoprimsulfamethoxazole (MJ Cenizal, D Skiest, S Luber, R Bedimo, P Davis, P Fox, K Delaney, RD Hardy. A Prospective Randomized Trial of Empiric Therapy with Trimethoprim-Sulfamethoxazole or Doxycycline for Outpatient Skin and Soft Tissue Infections in an Area of High MRSA Prevalence. Antimicrobial Agents and Chemotherapy 51:2628-2630, 2007). Frank Lastra | Physician | Disclosure: None Peak 10 | New Port Richey, Florida USA September 4, 2008 This case is not atypical in my rural community. Having isolated cases of MRSA recently in similar patients to the one presented, I would incise and drain plus add antibiotic for MRSA. I believe this would be the most prudent way to treat. Adam Bursua Pharm.D., BCPS | Other health professional | Disclosure: None University of Illinois at Chicago | Chicago, Illinois USA September 4, 2008 In addtion to I&D would empirically cover CA-MRSA because the patient fits profile for CA-MRSA infections including: Close contact with others including possible sharing of athletic equipment (basketball player), previous antibiotic use, presence of abscess. Would chose clindamycin if local sensitivity patterns allow, because of its good staph and strep coverage and suppression of PVL toxin. Would avoid beta-lactams as pt already failed amoxicillin alone, although presence of abscess may have confounded this result. Some studies have suggested I&D alone is appropriate, but another suggests antibiotic choice influences outcomes. Edna PIERRE | Physician | Disclosure: None VSAT-Systems, LLC | Port-au-Prince, Haiti September 4, 2008 In this context,the prevalence of MRSA infection, the patient occupation, the size of the lesion justitify the use of anti-MRSA therapy. The patient' story doesnt show any particular conditions that can prevent the use of antibiotics, while we waiting for culture and antibiogram results. Janis Wilkinson | Other health professional | Disclosure: None Clovis, California USA September 4, 2008 recommend since there is a high rate of mrsa in the community with athletes i/d and coverage for mrsa David Young MD | Physician | Disclosure: None Kaiser Permanente Medical Care Program | Fresno, California USA September 4, 2008 Over half of our community acquired staph infections are MRSA. There is a quicker resolution of sx's with I&D and antibiotics than with I&D alone. Antibiotics alone is a course that frequently leads to grief with the pt much sicker and having a bigger abscess/furuncle that needs to be drained and/or debrided a few days later, or even with positive blood cultures and sepsis in a minority of patients. francy yepes | Medical student/physician in training | Disclosure: None bogota, Colombia September 5, 2008 in this case of the infection whit mrsa, the dreinage alone is not beneficial because is necesary oral antimicrobial therapy; the infection whit mrsa is very dangerous and progressive, whit a short course antibiotics can limit the infection without opening the skin and diminish the focus for other opportunistic infection, in a person exposed to this risk in their day to day. Warren Tripp MD, FACEP | Physician | Disclosure: None CHARTER COMMUNICATIONS | Stoughton, Wisconsin USA September 4, 2008 The key to success is adequate drainage and the key to that is visualization of the liquid debris with bedside ultrasound Geren Nichols MD | Physician | Disclosure: None Kaiser Permanente Medical Care Program | Fresno,CA, California USA September 4, 2008 These MRSA abscesses involve more necrotic fat than pus and the debridement should more resemble excision and drainage than stab incision and drainage. This rather characteristic looking MRSA infection (in this case a early example) has been our standard outpatient subcutaneous infection since 2000. Gabriel Israel Soto | Physician | Disclosure: None Mexico, Mexico September 4, 2008 MRSA is one of the leading causes of skin and soft tissue infection acquired in the community Chitra Iravatham Dr. | Other health professional | Disclosure: None Hyderabad, India September 4, 2008 Apart from the treatment suggessted i would also would like to screen for AFB . As unhealead ulcer or infection abscess sometimes reveals Acid fast bacilli. We have dealt few cases in which MRSA associated ulcers have co infection with AFB. juan gomez | Physician | Disclosure: None WAW NETWORKS LTDA | bogota, Colombia September 4, 2008 Results from several emergency room departments throughout US show how frequent CA_MRSA occurs; and Yes, he has risk factors for harboring this organism such as playing contact sports and finally we would not want to risk his next game. Drain, culture and explain possible side effects of a short course of Tmp/sx avoiding risk of antibiotic colitis or induction of resistance. If resistance is found on Staph, this will serve too for conseling of the team and appropiate maneuvers. Elle Gold M.D. | Physician | Disclosure: None Comcast Cable | Decatur, Georgia USA September 4, 2008 would obtain culture & sensitivity before starting therapy. Gustavo Galue | Physician | Disclosure: None Carle Clinic Association | Bloomington, Illinois USA September 4, 2008 Practical clinical data assures that safety of patient is paramount and that benefit from treatment and redcution of complications outweigh the risks Michael Shay Sabom, M.D. | Physician | Disclosure: None BellSouth.net | Norcross, Georgia USA September 4, 2008 I believe the other options listed are not only incorrect but they are negligent. Doxycycline and Bactrim are cheap, generally well tolerated when taken with food, and show good effectiveness against MRSA. You cannot take a chance with this bug. It's too aggressive and more than once I have seen patients treated with MSSA regimens go to surgery for operative debridement due to a DELAY in proper antibiotic coverage. Scott Camazine MD | Physician | Disclosure: None Boalsburg, Pennsylvania USA September 4, 2008 This is the current management we opt to use in our ER in central PA. Here, well over 50% of such skin and soft-tissue infections are MRSA. I suppose we will have to await further studies to determine whether chlorhexidine scrubs and intranasal bactroban are warranted in attempts to decolonize patients (and families) where we commonly see the development of multiple recurrent infections. Jason Tompkins MD, MPH&TM | Physician | Disclosure: None CHINANET Shanxi(SN) province network | Berrien Springs, Michigan USA September 4, 2008 If there were no lawyers in the USA I would choose option 1. Lawyers make option 3 the safest, but a short course of doxycycline or TMP/SMX is favored over more expensive options. William DeMedio | Physician | Disclosure: None D&E Communications | Lancaster, Pennsylvania USA September 4, 2008 Incision and drainage always raises the risk of septicemia. A dentist would not pull an abscessed tooth without antibiotics in the bloodstream. Nor should we risk sepsis by draining an MRSA abscess. History and standard of practice support my views, as the vast majority of physicians use antibiotics prior to I&D that I know. I have yet to see sepsis post drainage in my practice or case reports in the literature. In the same way we have nearly eradicated rheumatic fever;no one would treat strep throat vs non treatment. Look back on the US civil war statistics if you want to know what happens to people who have infections surgically manipulated-they get what was called blood poisoning (sepsis).Often they died as a result. A large double blind trial in humans would be unethical regarding the use vs non use of antibiotics in infected surgery. By the way, I saw no reference to tetanus update. A boil I&D is a tetanus prone wound; was it overlooked or simply not stated? Anthony Mollano | Physician | Disclosure: None Metro2000 | Concord, New Hampshire USA September 4, 2008 As a hand and orthopaedic surgeon, i see lots of soft tissue infections, mild and severe, and i have very little experience treating this particualar type lesion with I/D only, and think that is risky. Antiobiotic coverage should just be based on cultures and i start empiric treatment given the extent of MRSA with anti-MRSA coverage to not risk this become a more serious life threatening problem, and then tailor down to anti- MSSA therapy only if cultures support this. John Murphy E. | Physician | Disclosure: None BellSouth.net | Dayton, Ohio USA September 4, 2008 In todays world you have to consider MRSA in every open lesion. How do we know this was not a fistula from a rectal absces? Where exactly was the lesion? Carolyn Fiutem | Other health professional | Disclosure: None Fuse Internet Access | Cincinnati, Ohio USA September 4, 2008 In our community, CA-MRSA is very prevalent and a number of cases are seen daily in our ED and physician offices. We have seen numerous cases associated with student-athletes (including my own daughter) and a significant number have repeated recurrences over time. I&D and antibiotics (usually Trimethoprim-Sulfa) have been very successful at reducing the number of Returns to the ED within 72 hours. About 70% of all Staph aureus isolates tested at our Micro lab are MRSA with an admission prevalence of 14% at our institution and another institution in our community. Due to the sequelae associated with CA-MRSA infection in addition to the apparent prevalence, a decision to use I&D and antibiotics was made by a multi-disciplinary group at our facility. Ismail Lawal Dr. | Physician | Disclosure: None NewCom International | Abuja, Nigeria September 4, 2008 Based on my 5 years experience working in the tropical region like Nigeria, I normally do I&D then follow up with anti biotic based on the result of microscopy, culture and sensitivity. Simple staining to view the offending organisim guide the choice of drugs, however I&D goes a long way with nonsteroidal anti inflammatory drugs for 24hours while awaiting the result of MCS. Thorsten Jørgensen MD | Physician | Disclosure: None Naerum, Denmark September 4, 2008 I prefer option 3 due to the addition of chlorhexidine and the consideration on behalf of the patient that addition of antibiotics may get him back to work(sport) sooner. shobhana sugirthamuthu | Physician | Disclosure: None Chennai, India September 4, 2008 Since more than 50% of soft tissue infections are associated with MRSA infections, option 3 would be the best for this patient David Ernst MD | Physician | Disclosure: None Comcast Cable | Fairfax, California USA September 4, 2008 What about using both anti-MSSA and anti-MRSA antibiotics until culture results are available? Also,would clindamycin cover both forms of Staph and provide coverage for Strep? Should attempts to eradicate the carrier sites (nares, axilla, groin) with topical mupirocin and chlorhexidine be tried with the initial infection? Ramakrishna Pinjala Dr | Physician | Disclosure: None Hyderabad, India September 4, 2008 Sports persons are likely to have community acquired MRSA infection and it may result in delayed recovery and healing. Incision drainage, Personal hygeine, Chlorhexidine soap, Tab. Trimethoprim + Sulphamethoxazole twice daily would be useful in such patients. This can be cost effective too. thangam palanichamy | Physician | Disclosure: None Reliance Infocom Ltd | tricy, India September 4, 2008 he was already treated with antibiotics without much response. so, incision and drainge , anti mrsa treatment is a must for him EMILIO CROSBY M.D. | Physician | Disclosure: None Telefonica del Peru | LIMA, Peru September 4, 2008 i AGREE WITH OPTION 3 BECAUSE OF THE LIKELIHOOD OF HAVING A MRSA INFECTION. Jihad Arteh | Medical student/physician in training | Disclosure: None Memphis, Tennessee USA September 4, 2008 I would choose option 3. I would like to stress that antibiotic therapy should be based on local epidemiology. In our residency practice in Memphis for example, we tend to be proactive about treating skin infection with specific coverage for MRSA – and particularly in this patient who, yes is otherwise healthy but he is an athlete which puts him at risk for Ca-MRSA. We had a similar case just recently, a young man, basket ball player who came with facial abscess with similar features as mentioned in the Vignette, we empirically treated him with Abx converging CA-MRSA, we performed I&D and specimen culture grew CA-MRSA. We take this approach for all the reasons that Dr. Kamitsuka mentioned in his explanation: I would point out the positive effect of Abx on the carriage rate, recurrence, favorable clinical resolution and last but least the fear of missing an impending doom. Moreover, in this patient, would recommend to avoid contact sports until his skin infection is healed or completely treated. Cesar Prinzac | Physician | Disclosure: None Telemar Norte Leste S.A. | rio de janeiro, Brazil September 4, 2008 Considering the size of the abscess, the need for a fast recovery and the high prevalence of CA-MRSA in the comunity it would be reasonable to treat according to the option three. I would also add nostril treatment with mupirocin. Fortunato Procopio | Physician | Disclosure: None Cox Communications | Kingston, Rhode Island USA September 4, 2008 Given his status as a competitive athlete, the size of the lesion and the surrounding erythema and the prevalence of MRSA in my community, I would be a bit more aggressive regarding treatment because of his close contact with multiple individuals and equipment. It must be emphasized that his wound must be completely covered for him to return to competition. Treatment is not a reliable mechanism to erradicate colonization. Re-colonization in the individual is common. The team trainers should be informed of the infection and advised to re-educate teammates regarding skin infections - what to watch for and how to avoid them. Aggressive cleaning and covering of wounds to avoid infections is extremely important. Were this someone who was not a competitive athlete I might have simply advised I & D with very close follow-up. In either case, culture and sensitives are important to direct therapy. However, I would include an antibiotic effective against MRSA in my initial choice. Jackie Kirby FNP-BC | Other health professional | Disclosure: None Greenville, Kentucky USA September 4, 2008 As a new FNP in my first yr of practice I have treated multiple furuncles that were erythematous, edematous tissue, non-draining with warm compresses qid to promote drainage and bactrim ds bid x 10 days. If draining at office, I obtained cultures. I don't recall one that did not respond well to Bactrim. Ramon Perez | Physician | Disclosure: None Anaheim, California USA September 4, 2008 Drain, antibiotic, hygiene, educate, culture and follow-up. MRSA skin infections have been reported in wrestling, football, rugby, soccer, basketball, field hockey, volleyball, rowing, martial arts, fencing, and baseball. USA300 MRSA is common among men who have sex with men. Necrotizing fasciitis caused by community-associated MRSA is an emerging clinical entity. MRSA was the most common identifiable cause of skin and soft-tissue infections among patients presenting to emergency departments in 11 U.S. cities. Percentage MRSA varied from 18.6% in North America to 46.0% in the Western Pacific. The outpatient prevalence of MRSA in the USA varied from 36% to 63%. In Los Angeles, the proportion caused by MRSA increased from 29% in 2001 to 2002 to 64% in 2003 to 2004. A study at Rocky Mountain Laboratories in MT showed that the two major epidemic CA-MRSA strains and the same strains with PVL removed are equally effective at destroying human white blood cells. Tamara Lyday | Physician | Disclosure: None Comcast Cable | Western Springs, Illinois USA September 4, 2008 Majority of cultures are coming back positive for MRSA so my first line treatment involves antibiotic coverage for MRSA. Denice Barnes M.D. | Physician | Disclosure: None RCN Corporation | Langhorne, Pennsylvania USA September 4, 2008 In my pediatric practice north of Philadelphia, almost any abcess is MRSA untill proven otherwise. We started seeing it about 8 years ago and it has become much more prevalent over time. We now have a number of families who have multiple members with recurrent infections. When someone has a small lesion with no systemic symptoms we start with warm compresses. I tell them 20 min 6 times a day in hopes that they will do it at least 3 times a day. I roll the culture swab over the top of the lesion if there is ANY hint of drainage and send them home with a culturette with instructions to "get me some pus, I LOVE pus!" I have them come back in a few days. Many times the small lesions will resolve when they drain. If the lesion is large, I send the culture, start them on Bactrim, reinforce the warm compresses and have them come back in a few days. If the lesion is small, we drain it in the office. amit taneja | Physician | Disclosure: None Comcast Cable | chicago, Illinois USA September 4, 2008 This is a scenario, which is dealt with almost every day in any average to large sized hospital/urgent care center. With increased prevalence of community acquired MRSA, it would be foolish not to consider that possibility. Clearly he needs I+D. At the same time one should treat him with cheap oral anti-MRSA antibiotics waiting for culture-sensitivities. I would choose bactrim. Jay Kleiman MD | Physician | Disclosure: None Road Runner | Lake Forest, Illinois USA September 4, 2008 Although each of the 3 options have strong rationale, the sequele of a therapeutic failure is ominous IF MRSA is present and I+D does not result in complete resolution. Given this awareness, addition of appropriate antibiotics for MRSA to I+D offers the best risk/benefit approach. Brian Passalacqua M.D. | Physician | Disclosure: None University of Nevada, Reno | Reno, Nevada USA September 3, 2008 This has become a not uncommon presentation in my community. I have seen several young, healthy college-age students with community acquired MRSA in the last few years. William Busino Jr MD MD | Physician | Disclosure: None Capital Care CBO | Scotia, New York USA September 7, 2008 The clinical scenario is consistent with a cutaneous staphylococcal skin infection which primarily requires incision and drainage. Empiric antimicrobial therapy is a reasonable option. This therapy should cover the likely pathogens , which in this case include MRSA. Selection of antibiotics effective against MRSA, pending culture results, is appropriate. Therapy can be adjusted, if indicated. Stephen Chase Jr. | Other | Disclosure: None SWIFTEL COMMUNICATIONS | Sydney, Australia September 3, 2008 Activities of the past several weeks coupled with rapid onset symptoms make for a better than average likelihood of MRSA infection and perhaps carriage. Yale Bickel M.D. | Physician | Disclosure: None Verizon Internet Services | Long Beach ,, California USA September 3, 2008 The frequency of MRSA infections is increasing generally and especially in the athletic community, starting with wrestlers (with body/ skin to skin contact)... but in all communal living conditions (especially in a locker room set up)... increasing not only in hositals and nursing homes but in the community particularly with the methods of skin care in a locker room. The downside of treatment for MRSA with antibiotics is far less in terms of complications than neglect of such infections with I and D only, so post initial incision and drainage C&S I would start Vancomycin or such agent... until the C&S results return and stop only if the culture fails to reveal MRSA. Claudine Aguilera MD | Medical student/physician in training | Disclosure: None Comcast Cable | Oakland, California USA September 3, 2008 this is the standard treatment in the medicine department, but often not carried out by our surgical collegues Debra Wechter | Physician | Disclosure: None Virginia Mason Medical Center | Seattle, Washington USA September 3, 2008 If not fluctuant, I would treat with antibiotics first and no drainage, then followup closely. John Jovan Mr. | Other | Disclosure: None Comcast Cable | Billerica, Massachusetts USA September 3, 2008 Culture of the pathogen should be definitely taken (at the time of drainage) so that possible further adverse development can be drug treated. Joseph Donnelly MD | Physician | Disclosure: None Road Runner | Austin, Texas USA September 3, 2008 In our community, upwards of 80% of cultures yield MRSA. Therefore, we rarely perform cultures except in unusual cases, e.g., the immunosuppressed, or those with multiple drug allergies whom we choose to treat with I&D only. Many of these patients will have recurrent furunculosis, and this process, based on my clinical experience, seems to be mitigated by oral and intranasal antibiotic therapy directed against MRSA. marysia meylan, bsn, msph | Other health professional | Disclosure: None santa monica, California USA September 3, 2008 I am an epidemiologist with 20 years of experience in Infection Control. I spent the last 10 years at Childrens Hospital Los Angeles. I have watched the march of CA_MRSA & kept data on patients and statistics on the relative prevalence of both MSSA & MRSA. It soon became clear that starting ER patients, in the absence of rapid laboratory results (i.e.: PCR), on MSSA therapy was a poor option. It was decided to use clindamycin as therapy of choice for all patients presenting with an abcess or a suspicious wound. Jasper Ho | Other | Disclosure: None Air Products and Chemicals | Allentown, Pennsylvania USA September 3, 2008 A generous dose of plain old TINCTURE of IODINE works wonders for killing all sorts of bacteria including MRSA, Flesh-Eating Bacteria, and the like. Repeat the application of iodine every three hours for a total of three applications the first 24 hours and then once a day after that. First few times, the sting of the iodine is a sign that it works... if it doesn't sting, it means the wound has "scabbed" over. Won't hurt to also bandage a soap-cleaned silver coin over the wound. This is entirely optional... it would speed the healing if we use the silver coin. Nan-Yao Lee | Physician | Disclosure: None Tainan, Taiwan September 3, 2008 Concern about Community acquired MRSA John Duldner MD | Physician | Disclosure: None Strongsville, Ohio USA September 3, 2008 the key elements are I&D and culture. I start MRSA therapy and non-MRSA therapy for 3 days. Patient calls me for culture results and I tailor therapy that way. saves 2 full abx courses ad i know exactly what i am treating Robert Douglas M.D. | Physician | Disclosure: None MidMichigan Regional Health System | Midland, Michigan USA September 3, 2008 Treat the infection clinically as a MRSA infection. Wait for the culture and sensitivities or clinical response to the antibiotics chosen. I would choose Bactrim and Doxycycline for double coverage in my local area. If sensitivities show MSSA then I would consider changing antibiotics. I have seen MRSA infections rapidly worsen in individuals; therefore, I tend to be more aggressive. elizabeth gabay md | Physician | Disclosure: None Comcast Cable | bellingham, Washington USA September 3, 2008 MRSA is common in the community, so trimethoprim-sulfa has become my first choice for antibiotic therapy of uncomplicated cellulitis in most patients. Although incision and drainage may be enough to cure this infection, there is no way to predict whether or not this young man will go on to develop a more severe cellulitis even after drainage. If he lived in my household and I could see the wound every day, I would feel good about incision and drainage alone. But the reality of practice is that we cannot monitor our patients as closely as we like. A few days of an antibiotic is a small price to pay to ensure that he doesn't develop a more agressive infection. Erica Phillips-Caesar | Physician | Disclosure: None Joan and Sanford I. Weill Medical College and Grad | NY, New York USA September 3, 2008 Based on incidence of community acquired MRSA in our hospital and NYC I would treat this athelete with antiobiotics for MRSA in addition to I & D