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Support for Restful Sleep*
Patient Benefits:
• All-natural approach to restful and
recuperative sleep* 1-6
• Promotes relaxation with clinically effective
levels of theanine and a plant source of 5-HTP
• Supports a positive mood and healthy mental
function with targeted B vitamins*
• Supports neurological health with neuroactive
forms of folate (L-5-methyl tetrahydrofolate) and
vitamin B12 (methylcobalamin)*
• Easy to use—just one tablet daily
60 MILLION AMERICANS suffer from occasional sleeplessness—
resulting in less than optimal daily functioning.
Rest Assured with Somnolin*
10 Signs of Occasional Sleeplessness
Millions of Americans experience some form of
occasional sleeplessness without knowing it.
Occasional difficulty sleeping and staying awake are
actually two sides of the same coin, and many people
show subtle signs of sleep issues, such as:
•Occasional difficulty falling asleep
•Difficulty waking up in the morning or
waking up tired
• Microsleeps—very brief episodes of sleep, such
as “nodding off,” when otherwise awake
•“Zoning out” in the middle of a conversation
or task
•Difficulty concentrating, making simple
decisions, or doing math calculations
•Feeling emotional, crabby, or volatile for no
apparent reason
•Altered memory or judgment
•Clumsy and/or slower reaction times than
•Routinely falling asleep within 5 minutes after
lying down
All-Natural Support for Restful Sleep
Somnolin is an exclusive, unique approach to
promoting restful and recuperative sleep by
delivering a variety of specially selected, wellresearched ingredients:*
Theanine—may influence the generation of alpha
brain waves associated with a relaxed, calm state.*
5-Hydroxytryptophan (5-HTP) from the plant
Griffonia simplicifolia positively influences levels
of serotonin, a neurotransmitter that affects sleep
quality and nervous tension.*4
Neuroactive B Vitamins, including Metagenics’
source of bioavailable folate (L-5-methyl
tetrahydrofolate) and methylcobalamin, which
research suggests cross the blood-brain barrier to
provide support where it counts. Along with vitamin
B6, these nutrients support a positive mood and
healthy mental function.*
Two Tablets Supply:
Vitamin B6 (as pyridoxine HCI)................................... 40 mcg
Folate (as L-5-methyl tetrahydrofolate†).............. 400 mcg
Vitamin B12 (as methylcobalamin)...........................500 mcg
L-5-Hydroxytryptophan (L-5-HTP
from Griffonia simplicifolia).......................................200 mg
L-Theanine......................................................................200 mg
Other Ingredients: Microcrystalline cellulose, cellulose,
stearic acid, croscarmellose sodium, and silica.
Recommendations: Take two tablets daily or as directed by
your healthcare practitioner. May be taken during the day
and/or before bedtime.
Form: 30 and 60 Tablet Bottles
As Metafolin® U.S. Patent Nos. 5,997,915; 6,254,904.
Caution: Patients taking certain prescriptive medications (including MAO
inhibitors and other antidepressants) should avoid use. If pregnant, nursing, or
1.National Library of Medicine. Sleep Disorders. Available at http://www.
Retrieved 11/26/08.
2.National Institute of Neurological Disorders and Stroke. Available at
sleep_brain_basic.htm. Retrieved 11/26/08.
3. Juneja LR, Chu DC, Okubo T, Nagato Y, Yokogoshi H. L-theanine—a
unique amino acid of green tea and its relaxation effect in humans.
Trends in Food Science and Technology. 1999;10:199-204.
4.Meyers S. Use of neurotransmitter precursors for treatment of
depression. Alt Med Rev. 2000;5(1):64-71.
5.Jacob RA. Folate, DNA methylation, and gene expression: factors of nature and
nurture. Am J Clin Nutr. 2000;72(4):903-904.
6.Mayer G, Kroger M, Meier-Ewert K. Effects of vitamin B12
on performance and circadian rhythm in normal subjects.
Neuropsychopharmacology. 1996;15(5):456-464.
taking medications, consult your healthcare practitioner before use. Use with
caution when driving or operating machinery, may cause drowsiness.
hese statements have not been evaluated by the Food and Drug Administration.
* TThis
product is not intended to diagnose, treat, cure, or prevent any disease.
©2009 Metagenics, Inc.
MET1029 01/09