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RNI No. DELBIL/2012/45560 DL(E)-20/5415/2012-14 March 1 st - 31 st, 2014 • ` 10/- • New Delhi Monthly Newspaper Vol - 2, Issue - 9 DRUG TODAY Health news delivered daily at drugtodayonline.com Ph.: (011) 22792078, 22792554 Medical Times Medical Institutions P3 Medical pharmacy MCI raids will now catch colleges by surprise B R A I N Y Q U O T E S “The more you like yourself, the less you are like anyone else, which makes you unique.” — Walt Disney DCGI revokes registration of Novartis In an unprecedented move against the European pharmaceutical giant Novartis, the Drug Controller General of India (DCGI), Dr GN Singh cancelled the Registration Certificate (RC) for import of Tiamulin hydrogen Fumarate manufactured by M/S Sandoz, Austria. Drug controller cited rule 21 of the Drugs and Cosmetic Act 1945 for the move. The stringent move is followed by submission of a fake document from M/s Novartis India Limited, Animal Health Business Unit, Sandoz House, Mumbai. Details on P4 P4 Pharmacist may become mandatory for drug stores Medical Review Campaign for direct blood transfusion takes steam Spurious drugs make it to hospital shelves Uttarakhand, Chandigarh come clean, other states shy away BS RAWAT DEHRADUN/ChandiGARH T here is lot of concern in the country over lack of proper healthcare system. But if we see what is going on in the name of public healthcare, we would prefer not to have any public healthcare system at all. Irregularities in the drug deals have been a matter of speculation for quite some time but the depth of malaise was not known. The recent revelations that 54 drug formulations in Uttarakhandand and 20 in Chandigarh hospitals and chemist shops across have been declared “substandard” by their respective Drug Control authorities gives an insight into the business. Uttarakhand had analysed 830 samples and the Union territory administration of Chandigarh 430 drawn by drug inspectors from different locations in the state and Union territory in the last five years in connection with the supply of spurious drugs in government-run hospitals/institutions. Even this expose could be just a tip of the iceberg as many other states have not made up their mind to part any information about the underhand dealings in drugs or simply rejected the request to do so. Through RTI replies officials of the Drug Controller Department of the two governments disclosed that their respective departments have taken prompt action after the report came in about the spurious and seized the tainted drugs, even as the inquiry is still on. “We have seized certain medicines from after the report by Continued on P3 No vehicle, no raid on quacks: DGHS to HC BS RAWAT NEW DELHI When the Delhi High Court asked the Additional Director, Directorate of Health Services of Delhi, Dr VK Aggarwal, about the reason for inaction in the case of quacks active in West and North West District of Delhi, the reply he gave is enough to send anybody into peals of laughter. Quack on bail to arrange Rs 7 lakh damages Riyazuddin, a quack, has been sentenced to three-year jail term for a series of wrong diagnoses that led to the death of a female patient. His bail plea was initially rejected by the court. But when he came in appeal before Delhi High Court and offered to pay Rs 7 lakh to the complainant he was released on bail. The court granted him twomonth bail on the condition that he should deposit the stipulated Rs 7 lakh in the name of 10-yearold Anjali, daughter of the deceased. In 2013, Riyazuddin was found “guilty of intentionally compromising the health of a woman Continued on P2 P6 The bizarre excuse that he offered was that there was no government vehicle made available to anti-quackery cell of the Delhi Medical Council (DMC). As was expected, the court was shocked at such a reckless reply from a senior bureaucrat that if anything reflects the insensitivity of the department entrusted with the responsibility of public Continued on P2 Pharma PSUs to ensure medicine at affordable price DTMT NETWORK In a move to provide medicine at a minimal cost to the masses that otherwise don’t have the accessibility to the expensive drugs, the Department of Pharmaceuticals has decided to procure the same from the drug manufacturing companies owned and controlled by state governments. The move in the offing is followed by a fiveyear pharmaceutical purchase policy adopted by the Union Government last year. Apart from providing drugs at a reasonable cost, it also intends to boost the sick Public Sector Units (PSUs) dealing with medicine. In this direction, the Government has already initiated a revival project. A person close to the development told DTMT that the five-year policy of the Government is applicable only to 103 drugs. It has been unanimously decided that these drugs will be sold by the PSUs and autonomous bodies at an affordable price. The discount in the price of the drugs will be decided by the National Pharmaceutical Pricing Authority (NPPA). Indian Drug and Pharmaceutical Ltd (IDPL), Hindustan Antibiotic Ltd (HAL), Bengal Chemicals and Pharmaceuticals Ltd (BCPL), Karnataka Antibiotics and Pharmaceuticals Ltd (KAPL), Rajasthan Drugs and Pharmaceuticals Ltd (RDPL) are the state owned PSUs. If the new policy is implemented, fate of these PSUs will be revived. The move will benefit needy patients and prove instrumental in saving many a life as life-saving drugs happen to be too expensive to afford for a majority of the patients in the country. The important thing that should need emphasis is that apart from providing medicine at reasonable price, there must be some mechanism to reach out to the needy patient with the medicine. The Union Government has already sanctioned Rs 145 crore for revival and meeting Good Manufacturing Practices (GMP) compliances for the BCPL plant which has four factories, two in Kolkata, and one each in Mumbai and Kanpur. DTMT Exclusive P14 Despite being curable TB on a killing spree in India Medical City 2 DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Rs 1.5L compensation for medical negligence 15 years on, AIIMS to get new blocks Swami Dayanand Hospital-EDMC to pay labourer for death of minor son BS RAWAT NEW DELHI The National Human Right Commission (NHRC) awarded a whopping Rs 1, 50,000 as compensation to be paid by Swami Dayanand Hospital and East Delhi Municipal Corporation (EDMC) to a labourer for the death of his minor son on September 3, 2012 caused by medical negligence. On the plea of RTI activist RH Bansal, the NHRC enhanced the amount of the compensation and asked the hospital and the EDMC to pay the amount to the father of the deceased child and submit proof of payment to the commission within six weeks. The commission observed that Rs 50,000 paid to the bereaved father by a guard convicted in the case by the court is inadequate and EDMC is required to pay some additional amount to compensate the loss of an innocent life. Consequently, the commission ordered the hospital and the EDMC to pay up Rs 1,50,000. An FIR, No 190/12 u/s 304A IPC, was lodged by the deceased’s father at GTB Enclave police station. Consequently, a thorough investigation was carried out in which a guard of the hospital was found guilty and was prosecuted. After his conviction, the court ordered the guard to pay a sum of Rs 50,000 to the father of the deceased, which he obliged during the court proceedings. The commission found the amount too inadequate for an innocent life and hence asked the Swami Dayanand Hospital and the EDMC to pay the entire compensation Rs 1,50,000 (which included Rs 50, 000 levied from the guard) to the deceased’s father. It also asked them to file a com- pliance report so that the same could be placed before it. NHRC had fixed the compensation amount on a RTI quarry referring to deceased father’s appeal to it while holding the contractor of the guard and the hospital culpable of civil liability for negligence. An RTI activist, RH Bansal, in his plea before NHRC had demanded a sum of Rs 1,50,000 compensation on the ground that both the hospital and the EDMC indulged in gross negligence leading to the child’s death. Two-year-old diseased, Pradeep, had come to the hospi- tal escorted by his parents, who were working there as labourers for the construction of a block in the hospital, in September 2012. At the hospital, he came in contact with a live wire and died of an electric shock. After the RTI query, the commission studied EDMC report on the case and came to the conclusion that there was negligence on the part of the hospital as it was the responsibility of the hospital to monitor the work. The report of the Deputy Commissioner clearly said that the Electrical Department of the EDMC failed in its duty in this case. Hence, it is clearly made out that the EDMC was responsible to monitor and supervise the work done by the contractor and they failed in this duty, which resulted in the unfortunate death of a minor. Hence a show-cause notice was ordered to be issued to the hospital, Delhi government and the EDMC. The notice has been responded by the EDMC and found the contractor guilty and was prosecuted. Earlier, the police had absolved the hospitals and the EDMC of criminal liability for negligence. Contractual paramedical staff raise banner of revolt JIVIKA MITTAL Paramedical staff is considered backbone of our health system. But unfortunately when it comes to giving their due, the very system which never tires of singing paeans in their praise develops cold feet. Take the case of Delhi’s paramedical workers. They have been struggling for their rights for more than a decade. But the administration always gives assurances which have turned into void. Around 2,500 contractual paramedical workers are working in various government hospitals in Delhi. These workers are hired by Delhi Subordinate Selection Services Board (DSSSB) after proper selection process. Many of these workers have been working on contractual basis for more than a decade. However, they have not been made regular or permanent em- Contractual paramedical staff holding a demonstration outside Delhi Secretariat ployees for reasons best known to the administration. These hapless workers have been protesting from time to time but the Government has adopted lackadaisical attitude towards them and shown scant interest in their genuine demand. “The Aam Aadmi Party AAP, despite including the promise to regularise all the contractual staff working for more than five years in their manifesto, failed to keep its promise,” said Niyaz Ahmed, general secretary of the Delhi Rajya Health Services Contractual Employees Union. “Recently, reacting to our strike held from February 10 to 14, which threw state’s healthcare machinery out of gear, the principle secretary of Health, said that the policy for your regularisation is already prepared and will be implemented in next two-three months,” added Niyaz. What is all the more intriguing is that DSSSB has been inviting from time to time fresh applications for permanent posts of paramedical staff. And if these posts are filled by the fresh candidates, what will come of these trained and experienced workers. “I am worried about my future as I can lose my job any moment,” a contractual OT lab technician of Ambedkar Hospital expressed his worst fears. Furthermore, in November 2012, the Delhi Government passed an order for same-pay for same-work, but these contractual workers have yet to get the salary that their permanent counterparts are drawing. No vehicle, no raid... Continued from page 1 health and safety. “It was very shocking state of affairs of the anti-quackery cell,” the court order observed and called for an emergency meeting of the officials of state Government, Delhi Police and Medical Council of India, Medical Council of Delhi, Central Council of Indian Medicine and other stakeholders to look into all aspects of quackery, the court asked the administration to ensure that no quacks are allowed to practice as it affects the very fundamental right to life of citizens under Article 21 of the Constitution. The DTMT in its February edition carried an exclusive report on DMC’s action against 38 quacks. But the action turned out to be a farce as all the so-called doctors were let off without any stringent and deterrent punishment. The anti-quackery cells of the Indian Medical Association (IMA)/Delhi Medical Association (DMC) have become redundant. All these years they have done precious little in curbing the menace. While DMC is competent to take suo moto action against quacks under Rule 32 of DMC Rules, 2003, it has never done so. There is no reason why the DMC, state Medical Councils and Medical Council of India should have anti-quackery cells at all when they hardly act against quacks. Proof of medical negligence, expert opinion, and legal action by medical council and involvement of the IMA can ensure that quacks are booked and punished quickly. After all, it is the duty of the medical system to fight against quackery. Quack to pay Rs 7 lakh Continued from page 1 patient” by the Delhi Court. Riyazuddin, who is an AYUSH practitioner, was allegedly dabbling in allopathy. “He wrongly diagnosed the patient and used the wrong treatments,” the court added. The court is convinced that the patient died as a result of wrong treatment at the hands of the convict. This may be the first case where a ‘doctor’ has been sent to jail for medical negligence. The case of Riyazuddin, which is still pending in the court, set a good precedent. It shows if an individual complainant/sufferer is determined, he can still nail those who indulge in quackery. Finally, the court has found it necessary to impale medical councils as parties. – DTMT BS RAWAT NEW DELHI After a delay almost long 15 years, foundation stone for the proposed Mother and Child (MCH) block and surgical block in the Masjid Moth area of All India Institute of Medical Sciences (AIIMS) was finally laid by Health Minister Ghulam Nabi Azad on February 3. The projects will add 600 more beds and 24 operation theatres at a total cost of Rs 255 crores. “Together these initiatives constitute a major breakthrough in the development of AIIMS infrastructure which has come under the severe strain due to increasing pressure of teaching, research and patient care activities,” Azad said, adding that the Plan and non-Plan budget for the current year was Rs 1,340 crore. The surgical block will be spread over an area of 17,000 sq meter and will have three basements and nine floors. It will have 200 beds, 12 operation theatres, a national endoscopy centre, a high dependency unit and transplant facilities. The facilities would be constructed at an estimated cost of Rs 55 Crores approximately and is expected to be ready by April 2015, Azad said. Further, the state-of-the art Mother and Child block will be built over an area of about 45,000 sq meters and will also have three basements and nine floors. The medical college and research university was established in 1956 and operates autonomously under the Ministry of Health and Family Welfare. DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Medical Institutions COLLEGES BEWARE! No more cheating! MCI to carry out surprise inspections JIVIKA MITTAL No private or government medical hospital will be able to hoodwink the inspection team of the Medical Council of India (MCI) any more by simply borrowing the infrastructure from some other hospital to get the approval of the MCI. Recently, the Executive Committee of MCI, on the basis of the judgment of the High Court of Delhi in the case of Raipur Institute of Medical Sciences Vs Union of India, has decided to conduct surprise inspections in all the medical colleges, seeking MCI approval for Under Graduation as well as Post Graduation courses. Earlier, the MCI used to inform the college about the inspection dates in advance. Owing to it, many medical colleges used to borrow faculty, laboratory equipment, library books and other infrastructural needs from neighboring institutions and present them before the MCI’s inspecting teams as their own to get MCI’s approval for their colleges. “This initiative of the apex body will help in keeping a check on the frauds which will ultimately help in maintaining the standard of the medical education in India,” said the MCI sources. MCI also decided to keep the video recordings of all the Inaugurated, maternity hospital still awaits opening A full one week has passed since its inauguration by a rickshaw-puller Bijay Baba, 60, amid much fanfare, but the newlyconstructed New Delhi Municipal Council’s upgraded Palika Maternity Hospital in Lodhi Colony, has yet to become fully functional. Patients continue to visit another hospital for biological tests and operation. If the hospital functions fully, it will be a great relief for all of them besides it would ease the burden on Charak Palika Hospital. When this correspondent visited the hospital, he found that people are getting only OPD services here. They were referred to another hospital for other facilities. Despite 65 beds, no ward service is available till date. Sources said that renovated maternity hospital will also offer laboratory services and immunisation and distribute drugs free of cost. DTMT Spurious drugs Continued from page 1 two laboratories reached us and we have also sent show-cause notices to various manufacturing companies in this regard. We are duty-bound to act against spurious drugs,” SC Sharma Drug Controller, Uttarakhand said in the reply. In its reply to RTI activist, RH Bansal, Uttarakhand Drug Control have listed 54 medicines as sub-standard. The drug inspectors found the samples of Paracetamol tablets, Diclofenac Sodium, Vitamin B Complex, Prazolam 0.25 tablets, Prazolam 0.25 tablet, Rem-CC tablets and E-PAR (paracetamol Oral Suspension) taken from CMSD stores and manufactured by a vadodara, Bangalore, Dehradun, Kashipurand Haridwar based companies as substandard and having the presence of particulate matters, the report said. The samples of the drug CZPAM 0.5 (Clonezpam Dispersible tablets) taken from the Forest Hospital Trust and Medical College, Haldwani also turned out to be sub-standard, the report mentions. Similarly, analysis of other drug from various institutes namely Aekil tablets, Azizen drops, Integesic-MR, Norfloxacin & Tinisazole tablets showed no clarity of the solution and presence of particulate matter, it said. The drug controllers also found that spurious drugs were being sold in chemist shops across the state, as many samples, taken from such shops in Bageshwar, Almora, Roorkee, Rudraprayag, Dehradun, Rudrapur,Pithoragarh, Haridwar, Srinagar,Chamoli, Pauri and Kashipur were found to be sub-standard. Similarly, the Drug Control officer, Chandigarh Administration has listed 20 medicines as substandard. It said that total sample collected during the last five year are 430 including 37 from the Central Drug Store, GMSH Sector-18, 30 from PGIMER, Sector 12, nine from GMCH Sector-32, 17 from ESI Dispensary, Sector-29, four from District Family Welfare Officer, Sector-22 and seven from Homeopathic Dispensary, Sector -34. The RTI activist RH Bansal is not happy with other state agencies. They failed to reply to his queries for some excuse or the other. The Government of Rajasthan which is pioneering free generic drug distribution, said refused to answer his query. Many other states including Uttar Pradesh, Punjab, Haryana, West Bengal and Bihar preferred to remain silent over the matter. He said he is planning to move high courts of the respective states if they do not send factsheets. inspections so that no one can claim the falsification in any means at the later stage. Recently, in the Raipur Institute of Medical Sciences Vs Government of India case, Justice VK Jain said surprise inspections must be conducted so that there is no scope for (i) arranging or admitting patients and (ii) arranging/hiring/ borrowing equipment or employing teachers, on a temporary basis. 3 Medical Pharmacy 4 PCI mulls making pharmacist mandatory for chemist shops MK SINGH The Pharmacy Council of India (PCI) is considering issuing a directive to all the state drug controllers and pharmacist councils to ensure that every chemist shop has at least one pharmacist. The move in the offing is aimed at implementation of the Pharmacy Act on the lines of Drugs and Cosmetics Act. Dr B Suresh, president of the PCI, told DTMT that the primary objective of the move is to ensure that patients get right medicine in the right dose and at the right time under the supervision of a competent person who could advise them on the safe use of medicines. For this, it is crucial to implement the Act in letter and spirit. The Pharmacist Act has a provision that each medical store should have at least one pharmacist. Moreover, section 42 of the Act provides for appointment of inspectors for ensuring implementation of the Act. "If the new directive is implemented, patients will be assured of quality medicine and expert guidance. This will also help avoid self-medication," added Dr Suresh. A lot of chemist shops in the country are managed by people who don’t know the basics about medicine. Quite often lure of the lucre draws people, even those who do not have proper degree or diploma in pharmacy, to the businesses of medicine. How can Dr B Suresh, president PCI “The primary objective of the move is to ensure that patients get right medicine in the right dose and at the right time under the supervision of a competent person who could advise them on the safe use of medicines. For this, it is crucial to implement the Act in letter and spirit” they do justice to a profession that requires sensitivity and precision? Despite the fact that the Act makes it mandatory for all medical stores to hire the services of a bonafide pharmacist, very few comply with the rule. The council has set aside funds to conduct the Continuing Education Programme (CEP) for pharmacists and directed that the pharmacists should complete two CEPs before registration. With more than one million pharmacists registered with the council and 700 institutes producing 40,000 pharmacy diploma holders annually there is no dearth of pharmacists. Hence, the challenge is not the nonavailability of pharmacists but the will to appoint them. Keeping in mind the safety of the patients with new drugs coming in the market it becomes imperative to know the useful and harmful effects of the drugs. The council has been constantly in touch with the Central and state governments and the councils to implement the same as soon as possible. It is doing so with renewed vigor to ensure patient welfare and safety, added Dr Suresh. For the betterment of pharmacists, the council has introduces a six-year D Pharma programme right after completing class 12th class . This programme will nurture them in their genre and will make them clinically competent pharmacists who can use their knowledge and skill in various Government and private hospitals and will be able to support patients along with the physician with unbiased information of medicines, said Dr Suresh. ICMR issues fresh guidelines for stem cell research DTMT NETWORK NEW DELHI The Indian Council of Medical Research (ICMR) has come up with fresh guidelines for stem cell research in India. The revised guidelines are aimed at restraining some clinics from exploiting patients by offering unproven stem cell treatment prematurely. Such a fraudulent practice needs to be stopped forthwith to ensure that significantly designed and responsible research on stem cell is not hindered, the ICMR contended in the guidelines. The field of stem cell research is still in its nascent stage in India. However, some significant advances have been made towards understanding the basic biology of stems and their differentiation into different cell lineage. However, harnessing of their promised potential to usher in the era of regenerative medicine is still a long way to go. In the guidelines, it has been decided to omit the word therapy. This has been done to emphasise the fact that the stem cells are still not a part of standard of care; hence, there can be no guidelines for therapy until efficacy is proven. “Any stem cell use in a patient must only be done within the purview of an approved and monitored clinical trial with the intent to advance science and medicine, and not offering it as a therapy. In accordance with this stringent definition, every use of stem cells in patient outside an approved clinical trial shall be considered as malpractice,” said the guidelines. These guidelines apply to all stakeholders including individual researchers, organizations, sponsors, oversight/regulatory committees and anybody associated with stem cell research. DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Legal Column Can a doctor run a pharmacy shop in his premises? Query: “Can a doctor who has a private practice have a pharmacy shop in the premises where he practices as per the Drugs and Cosmetics Act? If not, what is the penalty for doing so?” (Anonymous) According to Drugs & Cosmetics Act 1940 and Drugs & Cosmetics Rules 1945, no person shall himself or by any other person on his behalf can sell, stock, exhibit or offer for sale, or distribute any drug except under and in accordance with the condition of a licence issued for such purpose under the Act. No person has the right to purchase and sell drugs from his premises without a licence. The purchase of drugs for sale and possession without a valid licence would be illegal. The doctors/registered practitioners of modern scientific system of medicines can only stock or dispense Allopathic drugs/medicine to their own patients provided a doctor/registered medical practitioner is not keeping an open shop or selling across the counter or engaged in the importation, manufacturer, distribution or sale of the drugs. The doctors/registered medical practitioners shall purchase the drugs only from a dealer or manufacturer licensed under the rules and records of such purchase showing the names and quantities of such drugs, together with their batch numbers and names and addresses of the manufacturers. The doctor/registered medical practi- For any legal query you can write us at: [email protected] Dharamshila claims successful launch of Haploidentical bone marrow transplant The Dharamshila Cancer Foundation and Research Centre has started the Blood and Marrow Transplantation (BMT) through a procedure called “Half Matched or Haploidentical BMT”. The procedure is expected to be the last resort to 80 per cent of Leukemia, Lymphoma, Myeloma, Thalasemia, Aplastic Anemia and Sickle cell anemia patients in the country. Pointing out that 25,000 people require transplant in India annually, Dr S Khanna, president of the research centre, told DTMT that of these, only 10,000 could get the procedure done till a couple of months ago. The reasons for this lacuna are non-availability of matched donor and the cost of importing the stem cell from abroad, say for example the UK, the US, is too high i.e. Rs 25 lakh. Moreover, lack of awareness about BMT with half matched donor is one of the factors that used to UNDERSTANDING BMT n BMT is a procedure to replace the damaged bone marrow, a soft, fatty tissue inside your bones, with healthy bone m a r r o w Dr Sandeep Chatrath (CEO, stem cells Dharamshila Hospital nStem cells are immature cells in the bone marrow that gives rise to all blood cells There are three types of BMT: Autologous BMT: Stem cells are removed from the body before receiving high dose of chemotherapy or radiation treatment. The stem cells are stored in a freezer (cryopreservation). After high dose of chemotherapy your stem cells are put back into your body to make normal blood cells. Allogenic BMT: Stem cells are recome in the way of carrying out the procedure. Now, with the launch of BMT indigenously people RAMESH CHAND, ADVOCATE Nationally acclaimed expert on Drugs and Cosmetics Act (1940) [email protected] Mob-09810129898 (The views expressed in this column are those of the author and do not necessarily represent the views of, and should not be attributed to, Drug Today Medical Times.) RAY OF HOPE FOR CANCER PATIENTS DTMT NETWORK tioner should also maintain a record of the names of patients to whom he has dispense or administered the drugs in a register open to inspection by an inspector under the Act. A doctor/registered medical practitioner can purchase the drugs only according to requirements of his patients. Hence, doctor/registered medical practitioner has no right to establish a pharmacy shop in his clinic for sale of drugs to the general public/outer patients. He has to dispense the medicine to his patients by himself or through a qualified compounder or registered pharmacist. If a doctor/registered medical practitioner sells drugs from his shop situated in his clinic without a valid licence, he is liable to be prosecuted under section 18(a)(i) punishable under section 27(b)(ii) and liable to be punishable with imprisonment for a term which shall not be less than three years but which may be extended to five years and with fine which shall be not less than one lakh rupees or three times of the value of the drugs confiscated whichever is more and if the drugs found adulterated or spurious than he also liable for a imprisonment mentioned under section 27(a), 27(b)(i), 27(c) and 27(d) as the case may be. moved from a donor. The donor genes need to be partly matched with the genes of the receiver. Special blood tests are done to ensure that the donor is a good match for the receiver. Parents and siblings are most likely are good choice. If the donor genes do not match with the patient, one can go for registration for national or international bone marrow. Umbilical Cord Blood Transplant: This is a type of allogenic transplant. Stem cells are removed from a newborn’s umbilical cord right after birth. The stem cells are frozen and stored till they are needed for a transplant. Umbilical cord blood cells are very immature so there is less of a need of matching. But blood counts takes longer to recover in the procedure. A BMT is essential in cancers such as leukemia, lymphoma or both which is called myeloma. won’t have to look to other countries for stem cells. Apart from carrying out the procedure successful- ly we have been focusing on prevention of infection since infections have been major cause of casualties in the case of BMT in the past. For the same, we have created a state-ofthe-art infrastructure. We have built four rooms at a cost Rs 8 crore endowed with the best facility available nowhere in India, added Dr Khanna. “BMT is a very delicate procedure in which patients have to go through Immuno suppression where chances of infection are enormous. To overcome this, we have laid emphasis on the air catering unit, air pressure in the room. Beside, we have created vinyl cladding joint less-wall, stainless steel door among many, Happa filters of .3 microns to sanitise the BMT room of all infections. The BMT treatment is also quite affordable. The cost of the procedure ranges between Rs 6 to 15 lakh which otherwise would cost almost Rs 30 to 40 lakh if you go for imported stem cell, said Dr Sandeep Chatrath, CEO of the hospital. DBT research project to curb pre-term births DTMT NETWORK The Department of Biotechnology decided to undertake a multi-disciplinary research project to predict and diagnose Pre-Term Birth (PTB) by enhancing knowledge about the underlying pathophysiological mechanism. It has been decided that as an initial step the department will establish a hospital of a cohort of pregnant woman. Screening of pregnant women will start from the first trimester and each of them will be followed till delivery. Applying a crossdisciplinary approach, it has been proposed that possible mechanisms and outline the etiology of PTB should be elucidated. Whole genome screens, study of genomics, epigenomics and proteomics in different time frames will be done to access the biological risk factors and dynamic nature of PTB. Beside, the objective of the research is to achieve appropriate risk stratification of women in early pregnancy, identify simple and better prediction tools that will recognize the optimal time of prediction and clinical intervention. Globally, PTB is the single largest cause of neonatal deaths. In India, of 27 million birth cohorts born annually, 3.6 million are pre term and over 300,000 of them die each year. Directive against import of drugs with less than 60 pc residual shelf life DTMT NETWORK NEW DELHI The Drug Controller General of India (DCGI) has issued a directive restraining the import of drugs having less than 60 per cent residual shelf life unless the drug licensing authority relaxes the norm in the case of certain drugs which it may deem fit. The directive reads: “No drugs shall be imported unless it complies with the standard of strength, quality and purity if any. The licensing authority shall not allow the import of any drug having less than 60 per cent residual shelf life period as on the date of import.” As per the directive, the DCGI office can consider special conditions/circumstances under which the permission for import with less than 60 per cent found an edge especially for charity, national health schemes, when no substitutes are available and if the drugs required for treatment of disease which are specific to be of India origin, drugs meant for only testing and analysis purpose, orphanage drug for rare disease and to control the sudden outbreak of a disease. DCGI cancels Novartis registration certificate MK SINGH In an unprecedented move against the European pharmaceutical giant Novartis, the Drug Controller General of India (DCGI), Dr GN Singh cancelled the Registration Certificate (RC) for import of Tiamulin hydrogen Fumarate manufactured by M/S Sandoz, Austria. Drug controller cited rule 21 of the Drugs and Cosmetic Act 1945 for the move. The RC number BD-394 & Import Licenses issued under the said certificate has also been cancelled and in this regard direction from the drug regulatory authority has been issued asking that the stocks of the imported drugs available in the market, under the said certificate shall be recalled with immediate effect. The stringent move is followed by submission of a fake document from M/s Novartis India Limited, Animal Health Business Unit, Sandoz House, Mumbai. Along with the application, the firm has submitted Certificate of Suitability (CEP) R1-CEP 2004-176-Rev 01 dated 25/2/2013 for the drug THF, covering a different manufacturing site namely M/S Sandoz Industrial Products SPA, Italy. While evaluating the document, the Indian drug authority found that the firm has submitted the same CEP number of Austria and Italy. The matter was verified with European Directorate for the Quality Medicine (EDQM) and after an enquiry it came to light that the documents supporting M/S Sandoz, Austria is fake. Draft of a very confidential order available with DTMT says with respect to submitting fake document with a fraudulent motive and notarization of the fake document are concerned, the matter would be required to be investigated as per applicable law of the land. For this purpose the matter would be referred to the Ministry of Health and Family Welfare for their considered opinion for taking further legal action in the matter. ICMR norms for medical researchers DTMT NETWORK Indian Council of Medical Research (ICMR), the apex research body of the country, has issued guidelines on code of conduct for research scientists of life sciences. The move is aimed at ensuring that all research activities including into microbial, biological agents or toxins, irrespective of their origin and method of production, are meant for protective or other peaceful purpose. Since laboratory services are an integral part of disease diagnosis, treatment, response monitoring, surveillance programme and research, it is mandatory for the personnel working in the clinical or research laboratories to be aware of their ethical responsibilities. Taking cognizance of instances where scientific discoveries across the globe are being used for both peaceful and destructive purposes, the research council has stipulated checks and balances through the guidelines. It is of the view that modern technologies can be wittingly or unwittingly used to create organisms that are more virulent, anti biotic resistant and have greater stability in the environment. This advance genetic modifica- tion can be used to facilitate the immune response system of the host population with an intention to modify susceptibility to a pathogen or disrupt the normal host response. The guidelines said that in order to prevent the use of scientific research for purpose of bio-terrorism or bio-warfare, all persons and institutions engaged in all aspects of scientific research should strictly abide by this code governed by the principle of non- maleficence, principle of beneficence, principle of confidentiality, principle of compliance among many. The code of conduct lays emphasis on ethical considerations, which is binding on all the laboratories scientists involved in scientific research concerning dangerous organisms and toxic weapons against any living being or environment. DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Medical Paramedical INC relaxes rules for Tibetan nurses practicing in India DTMT NETWORK In a move that comes as a much needed relief for Tibetan nurses studying and practicing nursing in India, the Indian Nursing Council (INC), which had earlier issued a circular barring Tibetan nurses from practicing in the country, has reversed its decision. The INC has clarified that Tibetan nurses born in India (before July 1, 1987), being citizens of the country, can be registered to enable them to practice their profession. The Council will verify their birth certificates before registering them. Earlier, in July, 2013 the council said that Tibetans born and residing in India, being foreigners, cannot work as nurses in hospitals in the country. It also sent a letter to all universities and State Nursing Councils in the country, stating Tibetans, being foreigners, cannot work as nurses in India. “The issue of citizenship of Tibet- an refugees born in India has been clarified by the Hon’ble High Court of Delhi which has held that Tibetan nurses born in India have to be taken as Indian citizens,” the council explained. INC also stated that the issue of admission and taking up the profession of nursing for livelihood by Tibetan refugees in the country has engaged the attention of the council for quite some time, keeping in view the provisions of the Indian Nursing Council Act 1947. There are several Tibetans, mostly women, studying in nursing colleges or working in various hospitals all over India. The Government of India requires all Tibetans born in India to be registered as foreigners even though the country’s citizenship law states that all persons born in the country before July 1, 1987 are citizens. In 2009, the Delhi High Court ruled for judicial enforcement of this statutory provision in the case of a Tibetan petitioner. It directed the Government to issue passport to her as she was born in India during the relevant period even though it was contended by the state that she was already registered as a foreigner. However, most Tibetans born before July 1, 1987 do not possess birth certificates and continue to be registered as foreigners with temporary, renewable permits to remain in the country. Hence, those seeking to register as nurses have to follow a cumbersome process to prove their birth in the country to obtain the relevant certificate. Cough syrup as liquor sets new trend JIVIKA MITTAL During raids on the wholesalers and retailers of the drugs in Ghaziabad we checked the sale and purchase records of. On the basis of investigation, the license of three wholesale pharmacists got cancelled in the city. Recently, a drug inspector conducted some raids in different parts of Ghaziabad on the directions of Food and Drugs Depart- Draft rule on cosmetics Interview for pharmacists: Defending the indefensible test ban on animals DTMT NETWORK NEW DELHI Union Health Ministry of India adopted a draft rule to prohibit the testing of cosmetics on animals nationwide. A leading animal welfare group, Humane Society International (HSI), welcomed the draft rule, which is the last legislative step to end this practice in India. Be Cruelty-Free India campaign of HSI played a vital role in forcing the Government to come up with this legislation. The campaign is now focusing on obtaining a ban on the import and sale of cosmetics tested on animals in other parts of the world including India. HSI India managing director NG Jayasimha said, “Last year, our Be CrueltyFree India campaign was instrumental in obtaining a ban on animal test for cosmetics. The Government revised the Bureau of Indian Standards’ test guidelines to ensure that such tests are not carried out in the country. But to ensure that this test ban is executed within the existing regulatory framework amendment to the Drug and Cosmetics Rules is vital.” Pointing out that companies are still free to outsource their animal testing to other countries and to import their newly animaltested cosmetics and ingredients back into India, Jayasimha said this double standards must stop. Israel and the 28 countries of the European Union have already introduced an import and sales ban, India should follow their example to be truly cruelty-free. The Drug Technical Advisory Board has also spoken out in favour a ban on import and sales of cosmetic products tested on animals. The Board noted that the Ministry of Health and Family Welfare is already in the process of prohibiting the use of animals in testing of cosmetics manufactured in the country. India should therefore take a lead in prohibiting the import of cosmetics testing in animals also. JIVIKA MITTAL Even as state drug authorities keep justifying interviews for approval of manufacturing chemists there are certain pertinent questions left unanswered on the interview process in vogue. DTMT had carried an article under the title: “Mfg chemists kept on the tenterhooks” in its February issue. In the article, the state pharma councils vehemently defended the interview criterion saying they are crucial in judging the efficiency of the chemists in manufacturing drugs glossing over the fact that it has no mention in the Drugs and Cosmetics Act 1940. As per the aforementioned Act, any graduate in pharmacy with the stipulated 18-month experience in manufacturing is entitled to be a manufacturing chemist and get its approval from the state drug authority under rule 76 of the Act. In the light of the Act, are not these drug authorities acting in an extra-constitutional manner? We have found that these interviews are just eyewash. If they conduct these interviews to judge the efficiency of the person as they claim, are we to understand that all those manufacturing chemists in the trade approved by the authorities competent enough to carry on with the business of drug manufacturing? Is their record without blemish? The tradition of conducting interviews for manufacturing chemist is quite old. State drug authorities are routinely carrying out them for long. Why the fake drugs are occupying space on the shelves of the chemist shops? Who do they blame for this? They may argue that those who indulge in illegal practices do so not due of incompetence but for the lure of easy money. Is it not the duty of the drug control authorities to see that such unprofessional elements should not enter the field? Can’t they eliminate them through interview process? Subscribe NOW! 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Requests for replacement of lost/misplaced subscriber copy would be entertained within 30 days from the date of issue, subject to availability of the newspaper at our end. Loss due to failure to notify/give changed/incomplete address, will not qualify for replacement. Subscribers wishing to have Drug Today Medical Times through registered post may kindly send an amount of Rs 300 and Rs 900 for 1 year and 3 years subscription respectively. ment, UP. Deepak Sharma, Drug Inspector, Ghaziabad told that during raids, we checked the sale and purchase records of the wholesalers and retailers of the drugs. On the basis of investigation, the licence of three whole sale pharmacists got cancelled in the city. In January, in Lucknow the drug department of UP seized the Phesyndyl Cough Syrup bottles which was worth of rupees 20-25 lakhs. The syrup was seized as there were no record of sales and purchases. “The syrup if used in higher dose than the prescribed dose can cause the alcoholic effect, told Sharma. According to sources, these drugs were meant to be supplied in the foreign countries where the consumption of the alcohol is banned. As legally any drug cannot be exported exceeding to a particular limit. Therefore, the syrup was kept for illegal supply. After this, the UP FDA ordered all the drug departments of the state to investigate the matter thoroughly. Consequently, raids were conducted and the license of Balaji Medical Store, Mittal and Mittal pharmacy and Raj Medicos were suspended for failure to produce the sale and purchase records. Medical Review 6 DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi ALLOW DIRECT BLOOD TRANSFUSION, SAVE RURAL LIVES Campaign by surgeons gains momentum MK SINGH M any patients in rural India die for want of blood. These causalities can be averted if only blood is provided to them at an instant at the time of emergency. Association of Rural Surgeons of India (ARSI) spearheaded a campaign to save the lives of the people living in villages across the country. ARSI called for legalising the unbanked direct blood transfusion (UDBT) through an amendment in the Schedule K of the Drugs and Cosmetics Act. This, the association argues will give village folks easy access to blood and thereby help save millions of lives in the country. In this context, Dr Rajesh Tongaonkar, chairman of ARSI, wrote to the Union Health Minister, Chairman, National Human Right Commission emphasising the need for the UDBT. In his letter, Dr Tongaonkar pointed out that 70 per cent of the Indian population lives in rural areas which does not have access to the blood banks. As per estimation, 30 per cent of maternal mortalities occur due to haemorrhages (bleeding) while 19 per cent deaths are due to anaemia. Both these conditions need immediate blood transfusion to prevent death. Dr Tongaonkar said if the Government amends Act, it won’t be doing so for the first time. There is a precedence of amending the Act to save the lives of a soldier as the Government of India had amended the rule in schedule K way back in 2001 and had allowed Armed Forces Medical Services to do what is akin to UDBT in emergency situation. “Is the life of rural women or men is less precious than a jawan?” he argued. To buttress its argument, the association said in certain areas of the country there are no blood banks. Hence, it becomes imperative on the part of the Government to legalise the UDBT in line with the amendment it made in the case of armed forces. It further said that the UDBT can be included in the healthcare facilities in rural areas or small towns where blood banks are not available so that blood transfusion can be carried out in emergency situations and surgeries. Such facility will have a designated qualified physician n India has only 2545 licensed blood banks most of which are in cities n At present the D & C Act author- izes collection of blood only by licensed blood banks making the so called UDBT illegal n According to WHO a country needs Dr R Tongoankar From ARSI a minimum stocks of blood equal to 1% of its population. As per WHO estimates India needs 12 million units of blood a year, but only 9 million are collected n Earlier UDBT were allowed till 1998, but Govt amends the D & C Act to curb the HIV transfussion and adequately trained medical laboratory technician and will be licensed for five years by the state Food and Drug Administration. UDBT is done by the designated physician himself. In this procedure blood of a voluntary donor is taken and after conducting all the mandatory tests, immediate transfusion of blood is done without storing or banking. The mandatory tests include blood test, cross matching, test for HIV, hepatitis B, VDRL and malarial parasites. These tests can be conducted by using rapid test kits as recommended by the WHO. However, despite all the efforts of the association, UDBT has yet to be legalised as the Government has not taken any decision for the requisite amendment. Moreover, the NHRC rejected the proposal outright saying blood transfusion in such a way cannot be carried out as it will dilute the investigation of HIV/ AIDS. Beside, the National Aida Control Organisation (NACO) is also opposed to the idea. It argued that the move is fraught with dangerous consequences as it will dilute the prevailing system which stresses the need to avoid HIV/AIDS infection. However, speaking to DTMT, Dr Tongaonkar clarified that UDBT is absolutely safe as no HIV risks are associated with it as we did it with all the mandatory tests. Moreover, when it is allowed to save the Army personnel, why then the government is not considering it to save millions of countrymen. Why the rural folks are left at the mercy of the blood banks which of which they have no access. Claiming that Union Additional Health Secretary and Executive Director are of the view that the UDBT will save lives in the rural areas especially that of the expecting mothers so also the victims of road accidents, Dr Tongaonkar asked why then the NACO and Blood Transfusion Council is opposed to it. Dr Tongaonkar started his campaign for UDBT in 1998 by collecting blood from crossmatched donors in view of the scarcity of blood banks in rural areas. After conducting the mandatory tests, he gave it to the patients immediately without banking or storing it. Now, unmarried and divorced too going for IVF: Fertility Specialist BS RAWAT With Assistant reproductive technology (ART) techniques are breaking the social taboo divorced and unmarried men and women too are taking advantage of techniques. A new variation has been observed that older couples are also coming for taking advantage of these techniques. This is the observation of a well-known fertility specialist, Dr Anoop Gupta of Delhi IVF Fertility Research Centre Director. Dr Gupta, not the only in the country but also abroad, treated more than seven thousand couples Success rate of IVF then was Just 5 per cent. Today the success rate has reached to 50 per cent and such clinics have increased in number. But they suggest that before adopting this process couples should have a good heart and experienced doctor. A senior fertility specialist of Delhi IVF Fertility Research Centre, Mrs Alka Gupta, said, “These days even couples who have crossed 50-55 years of age are coming forward to give these techniques a try. Earlier, people used to give up all hope of bearing a child after a certain age. Rather it was expected of Cancer: Awareness and high index Dramatic rise in of suspicion key to early diagnosis joint replacement BS RAWAT NEW DELHI The number of cancer patients in India is increasing at an alarming pace. Annually, over 12 lakh people are diagnosed with different types of cancer and over 36 lakh patients are being treated at any given time of the year in different parts of the country. By conservative estimates, the numbers are expected to double in next two decades. Main reason for the spurt in cancer cases is the change in lifestyles – increasing use of tobacco, increase in fat and caloric consumption, sedentary habits, overweight, infections and change in dietary habits. Newer causes such as insecticides, pesticides, immunosuppression, and exposure to electromagnetic waves are under investigation. Dr R Ranga Rao, senior consultant and director, Medical Oncology, BLK Super Speciality Hospital, New Delhi said common cancers in men include lung, oral cavity, stomach and esophageal cancers and in women cervical breast, gall bladder cancers. According to Dr Rao, some major changes are being observed in the recent years in the cancer occurrence. Firstly, more young patients with cancers are being diagnosed nowadays. In India, people as young as 40 years, against 30 years in the West, are diagnosed with cancer. Secondly, some types of the disease such as lymphomas, lung, breast, ovarian kidney, colon and prostate cancers are surfacing more often. Treatment of cancer too has undergone many changes with increase in the rate recovery, survival of patients with advanced cancers. One of the important changes in the treatment is the use of person- alised therapy according to the type of cancers. Patients undergoing treatment need to educate themselves about various options and choose the appropriate one after discussing with their treating oncology centers. About 5 per cent patients have family history of some cancers. Frequent checkups and awareness can diagnose their cancers early. A detailed discussion of the family members with family oncologist is encouraged. Breast Cancer As lifestyles change in India, an increasing number of younger women have become susceptible to the breast cancer. “We see girls as young as 18 years with breast cancer. Due to urbanisation, lifestyle of people has changed by 180 degrees and the effect is visible. While the normal age for contracting breast cancer was anywhere between 45 and 55 years a decade ago, it has plunged to 35-45,” said Dr NK Pandey, cancer surgeon of Asian Institute of Medical Sciences (AIMS). According to Dr Pandey, breast cancer today is the most common cancer in most Indian cities, and second most common in the rural areas. The disease accounts for 25 to 32 per cent of all female cancers. This implies practically onefourth (or even approaching one thirds) of all female cancer cases are breast cancers. In India, the average age of developing a breast cancer has undergone a significant shift over last few decades. “Breast cancer can also be termed as a lifestyle disease.” Late marriage, fewer children and declining trend of breastfeeding are some causative factors, and all these are related to urbanisation. Obesity, which is related to lifestyle, is another cause.” said Dr Anita Kant, breast cancer expert at AIIMS. DTMT NETWORK NEW DELHI Osteoarthritis of the knee and hip are one of the five leading causes of disability among elderly men and women. The risk of disability from osteoarthritis is as great as that from cardiovascular disease. Similar disabilities develop with joint degeneration from rheumatoid, ankylosing spondylitis and many other causes of joint degeneration. Orthopedic surgeons say some problems may affect everyday activities such as walking, bending and use of stairs. Pain continues even while resting, both day of night and stiffness in joint limits ability to move or lift leg. Addressing a press conference on February 16, Prof Surya Bhan, Chief Joint Replacement Surgeon of Primus Super speciality Hospital, said in India, over the last few years, the volume of joint replacement procedures has increased dramatically due to increased level of awareness and improvement of technologies. Treatments of joint and knee problems have improved significantly with newer therapies and methodologies including the very exciting biologic disease modifying drugs and procedures like arthroscopy and joint replacements making tremendous impact on ability to treat various arthritis. Joint replacement surgery is one of the most successful procedures in orthopaedics. Prof Bhan, said, “a joint replacement can improve the quality of life tremendously by making the patient free of pain, deformity and physical dependence. Married for 15 years, the couple were blessed with three girls, Safa and Marwa and Sofia after IVF treatment. successfully for infertility and helped them have babies. About a thousand of the babies born through such techniques are twins. “Childlessness is a major problem in countries like India. In India growing number of couples are unable to produce offspring due to different medical reasons. But thanks to ART techniques many are now enjoying parenthood,” says Dr Gupta. Nearly 20 years ago Delhi IVF Fertility Research Center was established in Bengali Market in Delhi. This technology was fairly new then. People did not believe then that a baby could be born this way. them. There are many couples who rang the whining of children in the home from the ART technique.” Mrs Gupta says those couples who fail to achieve parenthood before 35 years of age should be treated with this technique for a meaningful parenthood. Whether or not the female ovum in fertility they are not then they are taken away from a female donor. Similarly, the male’s sperm may not be weak or if their fertility is taken from the donor. If for medical reasons, women are not able to conceive of such surrogacy is taken from another woman. Doctors say Indian men a KNOW YOUR ENEMY : neglected lot in healthcare Greying prematurely? Find solution in your lifestyle altering. Noting that most national health programmes focus mostly on comith a population of 1.3 billion, municable diseases and on children India has just a handful of urol- and women doctors at the conferogists cater to urological needs of ence observed that men’s health the public and men’s health remains in India has always been neglected a neglected area even though diseas- though diseases like cancer and es grip them two to four times more those related to heart and lifestyle afflict them two to four times more than women. To address the above mentioned than women. Over 1.3 billion Indian men are sufissues and discuss various health programmes that can be framed in fering from kidney disorders among this regard on a national scale, the other health issues but are unable Urological Society of India hosted to get early and effective treatment five-day 47th annual conference here due to dearth of urologists in India, from January 29. said Rajiv Sood, The conferhead of the urolence was attendogy department at Ram Manohar ed by over 3,000 Lohia hospital urologists from here. across India, Speaking at the SAARC counConference, he tries, US, Europe said: “Till now (UK, France, men’s health Germany and had no place in Spain) and Ausnational health tralia. During programmes. We the conference numerous im- Use of ring clamp to facilitate vasal fixation. only focused on child and women portant issues Courtesy : Brady Urology Foundation health.” of national con“We are unacern like organ donation and urinary genital cancers ware of the fact that the average life among others came up for discus- span of man is five years less than sion. A pre-conference live work- women in India. “There is fast-paced technologishop featuring robotic and laparoscopic surgeries in 3D was the high- cal advancement in urology and there are a number of options availlight of the meet. The focus was on the technologi- able for optimal patients’ care but cal advances like Fusion Biopsy and they are going unnoticed for want Photodynamic therapy for focal ab- of awareness,” added Sood, calling lation of prostate cancer and phar- for focus on newer equipments and macological advances in terms of drugs to cure urological problems of newer molecules that can be disease Indian men. DTMT NETWORK NEW DELHI W T here was a time when grey hair was considered a sign of wisdom. Times have changed. Grey is no longer a symbol of wisdom and exMadhuri Shukla perience. Now, even youngsters as young as in their early 20s have a grey hair here and a grey hair there protruding from their locks. Even as the problem is becoming more and more common, the reasons, causes and possible solutions of the prematurely greying hair are still elusive. What Is The Source Of Hair Colour ? Each hair strand has a follicle that originates under the root and the skin of the scalp. Within the hair follicle are cells which determine the colour of the hair. These cells produce colour pigment called melanin. Once melanin cell production slows down, the colour changes in each hair strand resulting in greying of hair. What’s Premature Greying? One reason for hair turning grey is reduction in the number of colour-producing melanin cells. Another reason is the build of naturally occurring hydrogen peroxide in the hair which bleaches the colour. With advancing age, hydrogen peroxide builds up in large amounts in the hair follicle and ultimately inhibits the synthesis of melanin. Hydrogen peroxide, or H2O2, is a by-product of a process by which cells burn fuel for energy. Generated in small amounts throughout the body, the chemical is normally neutralised by an enzyme which breaks it down into water and oxygen. With growing age, levels of the enzyme fall and hydrogen peroxide builds up in the follicle. On an average, white people start going grey in their mid-30s, Asians in their late 30s, and African-Americans in their mid-40s. Around 50 per cent of all people have a significant amount of grey hair by the time they turn 50. White people are considered prematurely grey if their hair turns grey by the age of 20, while grey hair before the age of 30 is premature for African-Americans. Greying begins to get visible when thicker darker hair-fall increases and there is an enhanced growth of thinner white hairs. This shedding of hair can last over a period of few months, or in some cases can be sudden fallout. Moreover, greying pattern varies in men and women. In men, it starts at the beard, then moustache, side locks and over time spreads to other parts of the head. For women, grey hair starts from the temples, and then it spreads to the sides. Why It Happens? Ranging from hormonal im- balance, thyroid, malnutrition, pernicious anemia, nutritional deficiency such as Vitamin-12 deficiency B Vitamins, iron, copper and iodine in daily diet, stress, use of electric dryers and concentrated hair dyes, as well as genetic disorders, all these factors provide causes for going grey. What Are The Solutions? Grey hair can be concealed in a number of ways. Semi-permanent ammonia-free hair colour is a good option for those who have just started to see grey hair. Coloured grey hair blends easily with natural colors making your mane look beautiful and natural. Permanent colour is recommended for those who have 45 to 50 percent grey hair. While greying is irreversible in most cases, checking the right nutrient uptake, maintaining a proper hair and scalp hygiene and leading a disciplined stress free lifestyle is important to prevent the problem from worsening. Regular healthy diet, proper hair and scalp hygiene and de-stressing activities are a must. Applying bhingraj oil to the scalp, substituting coffee for green tea and eating vegetables rich in folic acid, iron, vitamin D and vitamin B complex have been proven to be beneficial. The rejuvenating effect of yoga on the mind and body is well known, but many are not aware of the fact that practicing yoga asanas on a daily basis has wonderful effect on hair, especially if greying is due to stress. Routine practice of the inverted postures of yoga helps increase the blood circulation to the scalp and reduce greying. Some of these postures are Sirshasana (Headstand), Sarvangasana (Shoulder Stand), Halasana (Plough Pose) and Adho Mukha Vrksasana (Handstand). However, it is important to not over do these yoga postures and practice them within limits. Breathing exercises such as Pranayam involving alternate breathing from each nostril helps in maintaining a steady flow of oxygen in the upper part of the body, hence increasing the amount of blood flow to the melanin producing cells and taking good care of your long healthy locks. Finally follow your granny’s advice, eat lots of Indian gooseberries (amla) as they stimulate hair growth and quality, maintain a good hair care regime and flaunt your healthy, shiny, thick and dark locks! nBusting Myths w Popular belief: If you find a grey hair, do not pluck it as many more greys will grow in its place. w What science say: Plucking the hair will indeed get rid of the grey hair, but only tempo rarily. As the hair follicle is still alive and it will produce another hair to replace the one that was pulled out, how ever, it has no effect on its neighbors. Medical Voice DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Bronchial asthma – chronic, but complex disease FROM THE EDITOR’S DESK Knee-jerk action set a dangerous precedent Asthma being a complex disease needs to be handled with the utmost sensitivity. Awareness of patient and involvement of doctor are crucial for treatment, contends Dr Abhishek Kumar Medicos could have been brought around The high drama that culminated into a deadlock between medicos and the Central Government in Delhi held the medical system in the National Capital to ransom for some breathtaking moments that lasted for a few days. It all started with the threat of medical students and senior resident doctors of city’s top hospitals to go on an indefinite strike. The episode ended in an anti-climax when the medicos called off their agitation after an assurance from Union Health Minister Ghulam Nabi Azad that there was no proposal to extend the duration of MBBS Course, a demand that was agitating medical students for quite some time now. Earlier, doctors from AIIMS, GTB hospital, Safdarjung hospital, Maulana Azad Medical College (MAMC), Lady Hardinge Medical College, Deen Dayal Upadhyaya and RML hospital and medical students had demonstrated outside the Health Ministry headquarters at Nirman Bhavan, demanding revision of the proposed MBBS course structure. True, the strike had led to the closure of OPDs in many of the hospitals, causing distress to the patients. But the Government did not even once tried to bring the agitating medicos around through dialogue and reason. As always it was the Government to blink first much to the chagrin of the entire nation. The Government, in fact, conceded much more than the agitators had bargained for, that too, without much ado. There is no point arguing who was right and who was wrong in the entire episode. But one thing is clear, the Government ended up a loser. A release issued by the Health Ministry soon after resolution of the issue was drafted in a way to give an impression that the decision was not taken under any pressure and was followed by much deliberation but the facts were otherwise. It read: “He (Azad) listened to all their (the medicos’) concerns patiently and allayed their fears regarding Medical Council of India (MCI) Notification in respect of one year mandatory rural posting of PHC after completion of MBBS, before they seek admission to PG Course. The minister has directed concerned officials of the Ministry to keep the Notification in abeyance.” As far as the nation’s memory goes, mandatory rural posting for medicos has been a commitment of the UPA Government led by the Congress. Why this turnaround now? As a vast majority of people living in villages across the nation are deprived of basic medical facilities, the Government had taken a decision to reach out to them with medical services. Mandatory rural posting of medical graduates was seen as precious first step in this direction. If the Government had tried it could have succeeded in convincing the defiant medicos. By reversing its own decision, it might have bought peace with them for now but has lost its core constituency – the villagers – who have missed one last chance to get access to healthcare. This pusillanimous approach on the part of the administration is fraught with dangerous consequences. If it is doctors this time, it will be some other professionals next time around. If it goes on to concede to the whims of some group or the other holding the system to ransom, it will create a dangerous precedent which our democracy will ill afford. If people let the government decide what foods they eat and what medicines they take, their bodies will soon be in as sorry a state as the souls who live under tyranny. “ — Thomas Jefferson W hen people talk about bronchial asthma, what they really mean is asthma, a chronic inflammatory disease of the airways that causes periodic “attacks” of coughing, wheezing, shortness of breath, and chest tightness. Asthma is a common chronic disease worldwide. It is one of the most common chronic but noninfectious diseases that afflict childhood. The prevalence of the disease in adult population is 2.5 per cent or more. In children its prevalence is higher exceeding 5 per cent. The patho-physiology of asthma is complex as it involves airway inflammation, intermittent airflow obstruction, and bronchial hyper-responsiveness. Most types of asthma are linked to allergies. If you have allergic asthma, learning how to avoid your allergy triggers is a big part of staying well. In people with allergic asthma, the muscles around their airways begin to tighten. The airways themselves also become inflamed and flooded with mucus. The symptoms of allergic asthma are generally the same as those of nonallergic asthma. Allergens you inhale are most likely to worsen your allergic asthma. Some common allergens are pollen from trees and grass, mold, animal dander (from hair, skin, or feathers) and saliva, dust mites and cockroaches. People may also have allergic reactions if they touch or eat allergens but this type of exposure rarely causes asthma symptoms. Some irritants can also trigger an asthma attack, even though they don’t cause an allergic reaction. Tobacco smoke, air pollution, cold air, strong chemical odors like perfumes or other scented products, intense emotions may precipitate asthma attack. What patients should do? w Avoid asthma triggers: When pollen counts are high, stay inside as much as possible in order to keep dust mites out, wrap your pillows, mattress, and If you have allergic asthma, learning how to avoid your allergy triggers is a big part of staying well. The airways themselves also become inflamed and flooded with mucus. The symptoms of allergic asthma are generally the same as those of non-allergic asthma box spring in allergen-proof covers. If your child has allergic asthma, only buy washable stuffed animals. Remove wallto-wall carpeting, if possible. If moisture is a problem in your home, get a dehumidifier to cut down on mold. Repair any plumbing leaks. If you have pets, keep them out of the bedroom. Keep your kitchen and bathroom very clean to avoid mold and cockroaches. Change your work place if possible. w Recognise asthma attack The most common symptoms of an attack include: symptoms that keep getting worse, even with treatment like not able to complete a sentence, tightness in the chest, flaring your nostrils as you breathe, sucking in your chest or stomach with each breath, difficulty walking, the dose of your daily maintenance therapy to help control your asthma. w Self-care and optimal therapy For optimal asthma relief, it is important to participate in your care. With the help of your healthcare provider, you can get the best asthma relief by checking your peak flow and developing an asthma action plan. Keeping an asthma diary, avoiding asthma triggers, and learning ways to manage stress are important tools for better management. So, pay attention to your asthma symptoms. You may notice a pattern that can help guide you. Knowing your personal signs of asthma allows you to take action early, reducing the severity of your asthma attacks. What physicians should do? In a country like India where health expenditures are not covered by government, we need to educate the patients about management of chronic disease like asthma. Physician should get involved with the patient to know his or her lifestyle, work, socio-economic status and affordability of medications. Only prescribing medications are not sufficient. Despite a good advice patients keep coming with same symptoms. A number of medications may be needed for control of symptoms leading to poor compliance. Minimum medications should be prescribed, importance and specific use of tablets/ inhalers to be stressed. Patients should understand importance of each and every component of treatment. Main problem with inhaler is that the patients do not understand how to use it. It costs a lot especially latest long acting drugs. In dedicated clinics, doctors should pay time to demonstrate inhaler technique: individual and group demonstrations are needed. This avoids wastage of drugs, ensures better drug delivery leading to better control of symptoms. These steps lead to active involvement of patients in their disease management, stimulate them to take medications regularly and increase their confidence and, of course, give satisfaction to clinician. (The author is senior resident doctor at Lady Hardinge Medical College) Carlos Juan Finlay Alexander A. Maximow Discovered yellow fever. Born on December 3, 1833 in Cuba, Carlos attended the Jefferson Medical College in Philadelphia, Pennsylvania and later studied in Havana and Paris. He started practicing medicine in Havana and began researching on the cause of yellow fever during the 1870s. He discovered how yellow fever gets transmitted, via mosquitoes and not through humans. The discovery of stem cells is largely credited to Alexander A. Maximow. He was a Russian-American physician, biologist and scientist. Born on January 22, 1874 in Russia, Maximow studied in Germany and America and obtained an M.D. from the Imperial Military Academy in St. Petersburg. Alexander A. Maximow developed the theory that all cells come from the same precursor cell, which he later called as stem cells. PERSONALITY OF THE MONTH ‘Challenges and changes give me a high‘ It is a contrast that strikes everyone. Dr Suversha Khanna, who happens to be a qualified paediatrician, is, in fact, president of the Dharamshila Cancer Foundation and Research Centre. Her transition from a paediatrician to a crusader against the cancer is followed by the sad demise of her father who was diagnosed with prostate cancer at stage four. Noticing that there was dearth of treatment for cancer in the country, she decided to do something to ensure that in future nobody suffers the way her father did. Dr Khanna wanted to change the treatment situation in India and has successfully established the largest cancer hospital in North India. In the beginning, she faced many impediments; financial crisis being prominent among them. She took it as a challenge. Through grit and determination she could be able to make her dream come true. Her family and friends were her strength stood by her through thick and thin. She went ahead and registered an NGO with an objective of starting 300 beds with state-of-the-art comprehensive cancer care and research centre in Delhi. To live her dream she had to make many sacrifices. She had to give up her practice of almost 25 year and sell her family assets to fund the project. In an informal conversation with Maharishi Kant Singh, Dr Khanna spoke about her achievements and goals in life. Drug Today Medical Times: Tell us something about your childhood. Dr Survesha Khanna: Very happy, balanced and enjoyable childhood, except that to fulfill my dream of becoming a doctor I had to work a lot to convince my parents to put me in a medical college. DTMT: If not a doctor what would you have been? DSK: I have been a totally focused person from my childhood. I set my goals very clearly and work hard to achieve those goals. There was no question of not becoming a doctor. DTMT: Do you regret leaving practice as a paediatrician for almost 25 years, if not why? DSK: One regrets leaving old work if he/she is not enjoying new ventures, or is not able to achieve the set goals. Accepting challenges and changes gives me a high, which I enjoy. Completion of BMT project has really made me extremely happy and therefore question of regretting does not arise. DTMT: From pediatrician to president of leading cancer institute, how did you mange this transition without technical know-how and managerial skills? DSK: “Technical know-how” has to be learnt every day because technology keeps on changing very fast. If one is bluish or grayish tinge to your lips or fingernails usually in the background of running or stuffy nose, sore throat, and other allergic or cold symptoms. Now, what should you do if you have any of these asthma warning signs? Take two puffs of quick relief inhaler medication; repeat it two to three times if needed. If your symptoms are not controlled; consult your physician immediately. Your doctor may also need to change History makers Quote of the month “ 7 passionate about anything, one has to pursue every possible tool of learning with firm commitment and hard work. That is exactly what I did. Managerial skills: Since I come from a business family, I had been imbibing general managerial skills from my father, uncles and brothers. But at hospital one requires special managerial skills which I kept on learning every day. In spite of all this, every day there are new managerial challenges and one has no choice but to learn skills for managing crisis by attending conferences, workshop etc on managerial skills. DTMT: Five years down the line where do you see your cancer institute? DSK: In the next five years, Dharamshila should change the oncology scene in India by: nBecoming a national leader in blood and marrow stem cell transplantation by saving 500-1000 precious lives that are being lost due to lack to fully matched HLA donors n Downgrading cancer staging by early detection and prompt treatment n Improving 10 years cancer survival rates by optimum and high quality treatment n Decreasing morbidity and mortality rates of cancer. DTMT: North India’s largest cancer institute: in which parameters, infrastructure or service to the patient? DSK: We have 300 including 21 BMT beds Equipment: we have the maximum number of state-of-the-art equipment in each department for diagnosing cancer, finding out stage of cancer and treating cancer with world class technology. Expertise: we have maximum number of oncologists and all the other allied specialists to manage associated problems of cancer patients e.g. dental, ENT, neurological, hypertension , diabetes, kidney, liver, orthopedic, Gynae, Psychiatric, Psychoogical, speech and rehablitaiton. Systems and standards: Dharamshila Hospital and Research Centre is India’s first cancer hospital accredited by NABH, NABL and ISO TUV NORD for implementing integrated quality, safety and environmental management systems and standards. Care and service: We have thousands of satisfied patients who love us for compassionate care, ethical practices and transparent billing. Survival: In cancer five years survival and 10 years survival after treatment is the bench mark for different types of cancers and their stage. Prevention can be primary, secondary and tertiary. In primary we organise almost 15 awareness lecture per annum in Delhi/NCR, educate people through our website to make them know the risk factors, warning signs of cancer. Beside this we also educate for healthy lifestyle and fro self examination for diagnosing cancer at an early stage. In secondary we provide subsidized cancer check up, offering free cancer check up for the poor. In tertiary care we put all our efforts to save the patients. DTMT: Tell us something about the efforts that your centre puts in to save the patient at the last stage of the disease? DSK: It is not possible to cure patients of last stages but it is possible to add quality to their lives by providing palliative care or symptomatic relief. Depending on the specific problems of patients we go out of the way in providing palliative care by giving pain relief, e.g., oral morphine, nerve block: CARM guided, US guided and by continuous spinal analgesia inaccute or chronic pain. Besides, we go for Palliative surgery, Palliative radiation and Palliative chemotherapy. DTMT: Three things that make you smile? DSK: Achieving my goals nA thankful patient who has become disease-free n A successful cancer surgery which was highly challenging n A smiling, kicking, cooing baby, lush mountains, lakes, sea, rivers and musical dance of pines and wind in hills DTMT: Your suggestions to the young oncologists? DSK: Treat every cancer patient like your own kith and kin Avoid unnecessary procedures, drugs and hospitalisation. Become patient centric and stop being self centered. Be a friend, philosopher and guide for the teammates in real sense, ensuring their growth and development. Become excellent role models for others with ethical work practices. RAPID FIRE BORN ON 16th June, 1945 PLACE OF BIRTH Lahore HOBBY Music and climbing mountains FAV DISH Peas Pulao FAV HOLIDAY DESTINATION Kashmir and Europe ALL-TIME FAV READ Geeta, Upanishads Readers are welcome to write to us on any health and medicine related issue. We will be glad to publish the same on merit after suitable editing. You may email us at — [email protected] Visit us at drugtodayonline.com LETTERS TO THE EDITOR Interview for pharmacists is a dilatory tactic Sir, Apropos the news item under the title ‘Mfg chemist kept on the tenterhooks’ (DTMT, February 2014), I congratulate DTMT for raising a vital issue. There is no reason why there should be any interview for manufacturing chemist prior to their approval when the law sanctions none. Those who insist on it are behaving like extra-constitutional authority. The contention of the drug control authorities that the interviews are crucial in ensuring merit in the profession is untenable. The delaying tactics most bureaucrats adopt to deprive the citizens what is rightfully due to them is guided by anything but virtuous. And this is also a fact that most of them use this excuse to hide their ulterior motive. Inderjeet Singh, Pharmacist, Haryana Let the Govt come up with alternative to quackery Sir, Your editorial ‘Overhaul healthcare system’ (February 2014) was thought-provoking. I congratulate DTMT to bring such an important issue related to public health out into the public domain. Those who are at the helm of the country’s governance should not behave like dog in the manger. While they have long abdicated from their responsibility towards the poor and underprivileged, they seem to have decided not to allow others to do something to serve their interest. Granted, the quacks who treat the poor are not qualified enough to take precautions to treat them safely. What better option they have other than this. Does the administration have an alternative for them? Unless it has one, it should refrain from upsetting the applecart. Preeti Srivastava, Delhi Innovation keeps readers’ interest intact Sir DTMT is growing rich in both quality and content. Every month, DTMT comes up with newer and little known facts about medicine and healthcare. This saves the paper from becoming monotonous and the reader’s interest secure. The service you and your team have been rendering on humanity through this noble venture is praiseworthy. I wish you all the success. Keep it up. Somesh Kumar, Pune Medical Nation 8 DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Island of poverty and disease amidst opulence of city life A woman standing in front of her dilapidated house. (Inset) garbage strewn all around here alongside others. Well said, misery is great equaliser. Not a single clinic exists in the entire area to cater to the healthcare needs of the poor inhabitants. There is no water connection from any source including corporation water. Whatever little water is supplied, it is through a mosque borewell. Only 166 houses have toilet facility. Many houses here do not have power connection. Residents don’t possess ration or voter ID cards leave alone Aad- har cards or bank accounts in their name. Social security scheme of the Government like widow pension, old-age pension etc. does not reach many of the in- Early test to cut death risk in Oral cancer JIVKA MITTAL Cancer is the second leading cause of death worldwide. It is really shocking that 86 per cent of all oral cancer cases, reported worldwide are, take place in India. Currently over 23 per cent of all recorded cancer deaths in India are from oral cancer. The high mortality rate from oral cancer is due to several factors, but undoubtedly, the most significant is delayed diagnosis. According to experts the survival and cure rate can significantly increase if oral cancer can be detected in its pre-cancerous or early disease stages. To salvage the situation, Virtus Health Services India (VHSI) launched the O-Test in India, which is a non-invasive, highly affordable early stage detection test for oral cancer. The O-Test is supported by Virtus’ highly advanced automated screening software. This software designed by senior pathologists and applied to the entire process right from case history to medical examination and microscopic slide viewing, offers higher accuracy and speed of results generation. Mr Sunil Ikhe, Opera- tions Director and Country Head, VHSI said, “Given the significant morbidity and mortality associated with advance stage oral cancer, there has been a compelling need to provide doctors with an accurate and easy access diagnostic technique for early detection of oral cancer or even identity those at high risk. The O Test addresses this critical requirement at costs highly affordable and accessible to all sections of society.” The O-test has already been run on a pilot basis as an internal employee health benefit with some prominent corporates in India such as Edelweiss and Just Dial. In the roll out phase, a total of over 600 employees have been administered the O-Test. The globally widely accepted O-Test is expected to significantly reduce the rate of morbidity and mortality from oral cancer. The O-Test, a screening of the oral cavity works on two principles. The first is a five minute visual examination of Oral Cavity and identification of susceptible areas, if any which is conducted by qualified dental medical professionals. This is followed by the brush test, a non-invasive, painless, bloodless procedure which does not need local anaesthesia. The cells acquired on the brush are transferred to a microscopic slide for staining which is further analysed for cell abnormalities using the technical method. If any legions found suspicious or the cells are detected abnormal, the further tests are advised. habitants as most of them do not have any proof of identification whatsoever. As for educational profile of the area, of the 272 children in the age group of 3-6 years, only 83 go to school and 189 are either dropouts or have never been to school at all. Children in the age group of 7-18 years numbering 728 of whom less than 50 per cent i.e. 340 go to school. There is not a single graduate or postgraduate in the entire area. However, 18 children have completed their Pre-University Course (PUC) and 39 SSLC. Only seven children are pursuing their religious studies in Madrasas. There are many factors responsible for backwardness of this area. What is intriguing is that the local municipality too turns a blind eye to the civic woes of the residents. This is one of the slums of the city where unauthorised occupants are staying since ages. Politicians are not interested in improving their lot simply because they have a state in their backwardness. They think as wretched of the society they serve them better as vote bank at the time of elections. The living conditions here are so dismal that even access to basic amenities is not available to them. Since the roads are either so narrow or in such dilapidated condition that no vehicle, not even a two-wheeler, can enter the locality after a certain point. Family keeps Nepalese man in chains DTMT NETWORK KANCHANPUR It may sound strange, but it’s true. An apparently mentally ill man is kept in chains for the past 48 years in Malka Badayat of Shreepur VDC-6, southern part of the district. Kept in a solitary confinement, the man in his seventies has been deprived of treatment and is forced to live a hellish life due to poverty and lack of awareness. Badayat’s family decided to put him in chains in 1966 when he started behaving abnormally. For the purpose, they built a small hut (which itself is an incomplete structure) for him near the house. The hut cannot protect Badayat from rain and cold as it is open on all four sides and even mosquito bites. Badayat was taken to a local health institute and even to a hospital in India for treatment in the initial stages of the illness, according to his nephew Rajaram. He was brought back home following some improvement after one-anda-half month treatment. “But the problem persisted and we could not take him to hospital for further treatment. Rs 48,000 was spent on uncle´s treatment at that time,” he added. While some times Badayat expresses pain and sor- row by crying, at others he digs the earth with the help his nails. Once he even attempted to break the chain. Although married early, he has no children and his spouse, who was caring for her helpless husband since he was put in chains, died around one-and-a-half year back. Since then his nephew Rajaram is looking after him. Of late, he has lost his appetite, according to his neighbour Ganesh Rana. He complained that Badayat’s family visited local shamans for the treatment of ailing their member rather than a doctor which led to the deterioration of his health. DTMT NETWORK CHENNAI The Indian Institute of Technology-Madras (IIT-M) has announced setting up of a cancer tissue bio-bank, a first-of-its-kind community-based venture. At a press briefing here, IIT-M director Bhaskar Ramamurthi said the tissue bio-bank was a collaborative effort between the Department of Science and Technology (DST) of the Government of India, and IIT-M. The DST had awarded 27.81 crore towards the establishment of the facility in IIT-M and the project would be spearheaded by Professor S Mahalingam of the Department of Biotechnology. According to Bhaskar, the project was aimed at attracting voluntary contribution of cancer tissues by individual patients and doctors/ institutions. Such type of indigenous research was mandatory for progress in advancement of cancer therapeutics for the community. The community-based venture would help to reflect on cancer incidence, diagnostics and treatment outcomes, he said. The director also added that Research institutions/organisations with appropriate regulatory approval may have an access to the stored tissue samples with an aim to identify suitable drug targets and biomarkers IIT-M initiated the biobanking process with Cancer Research and Relief Trust (CRRT), Chennai, and aimed to collaborate with various institutions/organisations to encourage voluntary donation of cancer tissues by patients. “Measures will be put in place for appropriate collection, transport and storage of such tissues in the centralised tissue bank, which will be located within the IIT-M premises,” he said. Research institutions/organisa- tions with appropriate regulatory approval may have an access to the stored tissue samples with an aim to identify suitable drug targets and biomarkers. “This is aimed at discovering ‘personalised treatment’ with less side-effects, early detection and prevention of cancer,” Bhaskar said. Besides a complementary funding of 3.9 crore, IIT-M will also provide 10,000 sq ft of space for the biobank with required storage and security facilities. It will have infrastructure to accommodate 25,000 cancer tissue samples initially over a period of five years. Super-resolution imaging system, cell sorting facility and next generation sequencing facilities would also be housed in the biobank. Further, IIT-M would be involved in training, education and research of the next-generation biobanking process, said Bhaskar. Upon standardising the system and process within the central facility at Chennai, the process would be duplicated at nodal stations in peripheral areas, he added. The director also said that an ‘International Conference on Cancer Biology: Molecular Mechanisms and Novel Therapeutics’ - Cancercon 2014 - would be held at IITMadras from January 30 to February 1. The three-day meet is being organised jointly by the Biotechnology Department of IIT-Madras and the Cancer Research and Relief Trust (CRRT), Chennai. Around 500 delegates from across the globe, including the US, UK, Belgium, Sweden, Germany, Australia and Singapore, are expected to attend the meet. medical test nears ends DTMT NETWORK MUMBAI A four-year legal battle for gender-sensitive examination protocols in sexual assault cases is at the final stage. A judgment is awaited after the Nagpur Bench of the Bombay High Court concluded hearing into a PIL and an accompanying intervention application. Sangeeta Rege of the Mumbai-based Cehat, who had intervened in the original public interest litigation filed by Dr Ranjana Pradhi in 2010, said that on January 29, when the matter last came up and closed for judgment, the court asked the state to implement the protocols. The Centre for Enquiry into Health and Allied Themes (Cehat) had argued that the protocols and the pro forma for forensic ex- amination of a rape survivor have certain lacunae. It intervened in the PIL through the Lawyers Collective, seeking gender-sensitive protocols for rape examination and right to healthcare to survivors. Cehat objected to the focus on the height and weight of a survivor, the past status of her hymen and commenting on the elasticity of the vagina and the anus. “These points are biased against women, irrelevant and unscientific,” it said. The NGO argued that the definition of “rape” itself had been changed by the Criminal Law (Amendment) Act, 2013, and now covers nonpenile sexual assault that may not result in injuries. Often there are no injuries found in rape cases too, the court was told. H IN D IA IIT-Madras sets up bank for cancer tissues Battle for sensitive rape T National Centre for Research and Development (NCRD), an NGO, zeroes in on the most backward areas in a select city, district or block consisting of around 500-600 houses to carry on with its social activities. Recently, the NGO has chosen Devara Jeevanahalli as focus of its activities among several backward areas of the city. Given the pathetic infrastructure, subhuman living conditions and the civic mess the locality present, DJ Halli seems to be the right choice for NCRD’s activities. Most of the residents in DJ Halli are underprivileged and hence lead a life of penury with meagre resources, barely enough to make both ends meet. The irony is that the locality is surrounded by up-market Banga- lore suburbs which are home to rich and the elite of the city – truly an island of poverty and destitution amidst opulence of urban life. NCRD classified DJ Halli into 12 parts, each consisting of 50,000-60,000 households for its activities. The major problems the residents of this area are facing include chronic illness and physical handicap. Oldage, widowhood, damaged houses etc. With a population of just 2,683, the locality has a large chunk of people suffering from heart diseases, TB, cancer, asthma, diabetes, hyper tension, skin diseases, leprosy, deafness, kidney, abdominal ailments and other health related problems. The positive aspect of this locality is that even people affected by leprosy, generally made to live in segregation due to age-old myths against the disease, live SO U S AFSHAN AZHAR BANGALORE “An analysis of case records of 100 rape survivors brought to three Mumbai-based public hospitals showed that 50 per cent survivors reaching the hospitals were children and they did not exhibit injuries. This was also seen with adult women survivors who have reached hospitals within 24 to 48 hours,” said Rege, adding that the World Health Organisation, too, had noted that only a third of sexual assault cases display any injuries. “It is, therefore, critical that damaging indicators such as height and weight, and status of hymen (of survivors) be replaced with a gender-sensitive protocol for sexual assault examination at the level of hospitals,” a Cehat statement said. Now, quit-line for addicts to rub Vani Vilas – a boon for the underprivileged off the habit of tobacco DTMT NETWORK VISAKHAPATNAM A group of dentists and patients have joined hands under Tobacco Intervention Initiative (TII) in collaboration with the Indian Dental Association (IDA) to launch a toll-free helpline called quit-line for counselling tobacco users on phone. Dentists are now increasingly donning the role of anti-tobacco counsellors while treating patients addicted to cigarette and other tobacco products. Apart from six TII centres in Hyderabad, IDA is planning to train more dentists and open more centres across the state, including the coastal region. The tobacco-user can call the quit-line number for free personal counselling in any regional language. Call- ers receive counselling from trained tobacco cessation experts, who also give advice on medication to help fight withdrawal symptoms. The Tobacco Intervention Initiative (TII) is a professionally-led ‘call to action’ programme to eradicate tobacco addiction while striving for a tobacco free India and thus improving the oral health of Indians by the year 2020. Tobacco causes significant changes in a person’s mouth and counseling is the first step on the road to quitting. Counseling reveals the deleterious effects of continued tobacco use. The dental community is the first line of defense in early detection of the disease and risk factors associated with oral cancer. Oral health awareness and tobacco ad- diction prevention should be promoted more and more. Patients with tooth problems are identified with the tobacco-related cases, which are usually marked by blackened teeth, nicotine patches, loosening of teeth and gum problems. Doctors prescribe medicines and also counsel the patients based on their tobacco smoking or chewing habits, age, profession, whether they are social smokers or addicted to tobacco. However, the government needs to be more proactive in dealing with tobacco addiction and not give in to the lobbying of tobacco companies. More TII centres should be set up in other parts of the country as well. S AFSHAN AZHAR BANGALORE Located at the center of the Garden City of India, Vani Vilas Hospital is part of its rich heritage. Founded in the year 1935, the hospital, meant for women and children, is run by the state Government. This hospital has two departments viz. Obstetrics and Gynecology and Pediatrics. The Central and state governments have provided various schemes for the convenience of the patients. Under the Central Government, the ‘Pradhanamantri Swastya surakhsha Yojana’ scheme was launched which aims at correcting the imbalances in the availability of affordable healthcare facilities. On the other hand the state Government provides Janani Shishu Suraksha Yojane, under which all the deliveries including under Cesarean Section are conducted free of cost. Yeshaswini Yojane provides free gaynaecological advice and treatment till delivery. Speaking to DTMT, the Medical Superintendent of the hospital, Dr Some Gowda, MD, DGO, said that the hospital is one of its kind, where deliveries and neonatal care is free of charge to all patients. Of the 536 beds 420 belong to the maternity section, 80 to the pediatrics and the remaining 36 to the pediatric surgery. Forty to fifty deliveries take place here on a daily basis. Majority of the patients here belong to ei- ther middle class or poor families. There is a facility for special ward at a reasonable fee. However, deliveries and medicines are provided free of charge. All the neonates born in the hospital are given free treatment up to one year. Dr Gowda brought about positive changes in the hospital such as a musical centre which provides music therapy to the pregnant ladies. The hospital introduced a special ward for children suffering with Marasmus, a first in the state. “Now, use of Yeshaswini and BPL cards has come down because we are providing free service to all would be mothers. There is another scheme, the Vajpayee scheme, under which cancer patients and other surgeries like babies born with abnormalities, heart, brain, abdominal problems which may require higher surgery are also done free of cost. In all cases, laparoscopic method of surgery is used,” said Dr Gowda. “We are the first in Karnataka to introduce removal of uterus through laparoscope. Advanced surgeries like urogynaechology are also being done here instead of referring them to higher centres. ‘Malignant’-cancer cases are also operated upon, here,” he added. DTMT caught up with Dr Sudha, a gynaecologist at the hospital, for her views. She felt there was a scope for more facilities from the government because the flow of patients is large. Airing similar view, one of her colleagues, Dr Rashmi said, “We are doing our best to serve the patients. But, there is still much more to be improved due to shortage of man power.” The common refrain among the patients is that the doctors here are found to be quite caring. While they feel there is much to be desired by way of facilities, the nononsense and diligent service of doctors make up for this deficiency. DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Medical Nation 9 Watch out on your alcohol intake AORTIC COARCTATION The heart disease that to keep up the festive spirit comes without warning I t’s that time of the year when people generally lower their guard to enjoy the season of festival. You too must be looking forward to have a rollicking time gulping as much of alcoholic beverages as you can. But you need to take a look at your levels of alcohol intake this Holi to minimise the effects it could have on your health. Of course, you can enjoy the pleasure of drinks with friends. But it’s best to reduce your alcohol intake if you want to fend off its deleterious effects on the body. Apart from partying, you may look at the times you consume alcoholic beverages such as your weekly ‘happy hour’ or just taking a couple drinks at home to reduce stress. It’s said that moderate drinking may be healthy, but that doesn’t apply for everyone. For women, it is up to one drink per day; for men, up to two drinks per day. However, each person must weigh the benefits and risks of consuming alcohol. So, even if you go to an event, with beverages that are on the house or part of what you pay for at an all-inclusive party, you must make a decision to arrive home alive by drinking responsibly, especially if you are driving. Alcohol creates health problems for irresponsible drinkers. This is why it is important to drink responsibly to prevent the problem of alcoholic addiction, which can harm relationships. The long time effects range from possible health benefits for low levels of alcohol consumption to severe effects in cases of chronic alcohol abuse Psychiatric disorders associated with alcoholism include major depression, mania, phobias, suicide and panic disorders. Teen drinking: Adolescents who tend to drink excessively at parties and nightclubs may place themselves at risk for slower brain development and increased risk of alcohol abuse. Some experts argue that the benefits of moderate alcohol consumption may be outweighed by other increased risks, including injuries and acts of violence. Excessive consumption of alcohol is one of the leading preventable causes of death. According to the British Medical Journal, The Lancet, one in 25 deaths around the world is caused by alcohol consumption. Alcohol is now as damaging to global health as tobacco was a decade ago. Beware of unfamiliar drinks. Such drinks as zombies and other fruit and rum drinks can be deceiving, as the alcohol is not always detectable, and it is difficult to space them out. Remember that alcohol is still the No. 1 date-rape substance. When you drink that, you are out of control, putting yourself at risk of DTMT NETWORK KOLKATA Researchers from Netaji Subhash Chandra Bose Cancer Research Institute (NCRI), Kolkata, have found sojne danta (moringa oliefera), popularly known as drumsticks, has the potential to cure breast and ovarian cancer. They have discovered that there are certain compounds in the vegetable that can inhibit cancer cells and cause their programmed death. “We were experimenting with various plants when we came across the moringa root. It has two interesting compounds – glucosinolate and bengyl isothiosyonate – that kill breast cancer cell lines. It works under a mechanism that is called apoptosis and results in programmed cell death. It is effective in case of ovarian cancer as well,” said clinical scientist Chinmay Bose, head of the research. Ovarian and breast cancer are caused by the hyper functioning of estrogen hormone. The moringa compounds have been found to inhibit estrogen biochemically. “These compounds while “Glucosinolate and bengyl isothiosyonate in drumstick work under a mechanism that is called apoptosis and results in programmed cell death in breast as well as ovarian cancer” on the one hand control estrogen, kill cancer cells on the other. The moringa root has got more compounds that have yet to be identified which might have more properties that could help treat the disease more effectively,” said Bose. “The next step for researchers will be to identify the cell lines that are being blocked by the compounds. Cancer cells will have to be cultured for that. It has to be done in a particular laboratory environment that we don’t have yet. We will have to imports certain instruments from other cities and develop the laboratory. It won’t be easy but we are confidant of success,” added Bose. Ashish Mukhopadhyay, director NCRI said once the rest of the compounds are identified, the scientists will prepare for phase one clinical trial. The signs are encouraging and the research has the promise to be a path breaking one. The West Bengal has around 21,000 ovarian cancer patients, 60 per cent of whom turn drug resistant in two years. Of 48,000 breast cancer patient in the state, 30 per cent are resistant to drugs. This figure underlines the necessity for the development of the biological agents as a replacement for conventional chemotherapy. Around 20 per cent of the breast and ovarian cancer patient died every year, added Dr Mukhopadhyay. The research was started in 2012 jointly by the Indian Council of Medical Research and NCRI. Exotic imported foods bug bites small towns too Cancer is growing in all the north eastern states by leaps and bounds. Of late there has been a spurt in the number of cancer cases. While 2011 accounted for 36354 cases, the figure for 2012 and 2013 was 36814 and 37294 respectively. The data is presented by the cancer registries under the aegis of the Indian Council of Medical Research (ICMR). The North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS) geared up for the challenge. It created a state-of-theart infrastructure to combat the disease. The institute developed separate oncology wards with 16 indoor beds with a provision With state-of-the-art infrastructure two N-E institutes geared up for the challenge posed by cancer of further expansion up to 30 beds. Pain relief, palliative care facilities, regular screening programme are also conducted in the hospital. Beside, Dr B Borooah Cancer Institute, Guwahati has also come out to meet the Cancer challenge. It is has 209 beds, radiotherapy equipments like Linear Accelerator Machines with IMRT, IGRT, SRS/SRT and major equipments for radio diagnosis like CT scan and MRI, five fully equipped state of the art opera- JIVIKA MITTAL A dvocate Govind Sharma, 52, had been suffering from a life-threatening congenital condition called Aortic Coarctation. He came to know about this disease only recently when he stricken by a heart attack. Sharma was advised immediate open heart surgery to carry out a bypass for blocked coronary arteries and the repair of coarctation. Coarctation of aorta is among the most common congenital heart abnormalities. Coarctation means blockage or narrowing of aorta, largest artery which distributes oxygenated blood to all parts of our body. This disease is often detected in the first few months of birth when children develop symptoms of heart failure like breathlessness, poor feeding and growth. In adults, it is often discovered in the third decade of the life. Rarely, some people can walk around with their condition undetected for years like Govind Sharma. “It was really surprising that the patient survived for so many years without any symptom of Aortic Coarctation, which is very risky as he could have a severe heart attack at any moment. The diagnosis of coarctation of the aorta may be missed during early childhood unless an index of suspicion is maintained. DTMT NETWORK NEW DELHI Demand for cheese, tortilla chips, pasta, sauces and olive oil among others has gone up by 27-28 per cent in small towns recently against a 15-17 per cent growth in big cities, according to data from the Forum of Indian Food Importers. “The demand is booming in small cities. Exposure to international fast food chains through various food shows on TV has changed the eating habits of people,” observed Amit Lohani, convener of the Forum of Indian Food Importers. For instance, olive oil sales are growing by 50 per cent every year while imported pasta and cheese is seeing a growth of more than 30 per cent. The Indian gourmet food industry, which is growing at 20 per cent annually, is likely to top $2.8 billion (Rs 17,500 crore) by 2015, data from consultancy Technopak Advisors shows. “Small cities are where the future is,” said Jehangir Lawyer of Fortune Gourmet Specialities, which imports cheese, processed meats and seafood from Europe, the US and Australia. “The super six cities (Mumbai, Delhi, Kolkata, Chennai, Hyderabad and Bangalore) were earlier driving growth for imported food. Now we have identified 30 additional towns,” said Sumit Saran of SCS Group, which represents several US brands including California Prunes and Washington Apples. People from places such as Dhanbad and Bokaro to shop for imported gourmet food products, said Saikat Sarkar of retail chain Spencer’s., four buses to Nepal on Republic Day. A large section of the society in the country has no access to healthcare services. There are social, geological and economical factors that come in the way of reaching out to them with healthcare. These factors act like roadblocks in the way of achieving healthcare for all. To address these issues, Associated Chambers of Commerce and Industry of India (ASSOCHAM) recently organised a summit: “Access to Healthcare: Scaling up Best Practices”. The event brought policy makers, industry leaders, entrepreneurs, R&D professionals, academicians and students at one platform to raise awareness about the problem. This is the second time Assocham organised the event since 2011 to inspire the gathering to work together towards facilitating excellent healthcare facilities for the citizens of the country. The initiative offered a platform to discuss the state of Indian healthcare services and showcase tion theatres among many. Modernisation of these institutes and introduction of newer technologies is an ongoing process in this direction. As per information provided by Atomic Energy Regulation Board (AERB), Mumbai, there are as many as four institutions with radiotherapy facility in the public sector in the North-East region. Health being a state subject, the Centre supplements the efforts of the state governments here through inter alia, the Central Government health institutions and national programmes. In assisting the state governments the National Programme for Prevention and Control of Cancer, Diabetes, CVD and Stroke was started in 2010. Coarctation means blockage or narrowing of aorta, largest artery which distributes oxygenated blood to all parts of our body Generally, the diagnosis is delayed until the patient encounters the symptoms of the disease for long time. Stroke, brain aneurysm and early onset coronary artery disease, are some of the symptoms of the disease” said Dr Mukesh Goel, HOD and chief cardiac surgeon, Asian Institute of Medical Sciences. “It is estimated that 1 out of every 10,000 babies born have coarctation of the aorta, but diagnosed at such later stage of life is very rare,” added Dr Mukesh. The aorta is the main artery that leaves the left side of the heart (the left ventricle) and supplies oxygenated (oxygen-rich) blood to our body. The aorta is the main artery of the body and all of the other arteries of the body derive from it. In coarctation of the aorta, there is a narrowing in part of the aorta and thus blood cannot pass as easily through the narrowed part of the aorta. This means that the blood supply to the lower half of the body can be affected (less blood is able to get through). Also, because of the narrowing, the heart works harder to pump and try to squeeze blood through the narrowing. Because the heart is working harder to pump, this can cause blood pressure to rise which is the main symptom of coarctation of the aorta. The degree of narrowing in coarctation of the aorta can be different in different people. During a physical exam, the doctor may find that a person with a coarctation has higher blood pressure in the arms than in the legs. The doctor also might hear a heart murmur or notice that the pulses felt in the groin area or on the feet are weak or even absent. To judge the exact condition of the heart a cardiologist may perform some tests such as a echo, ECG, chest X-ray, a magnetic resonance imaging (MRI) test, or a computerized tomography (CT) scan. Call your doctor immediately if you are having high blood pressure, shortness of breath, chest pain, or fainting as it can be a silent knock of coarctation of the aorta. Healthcare access: Assocham meet takes up roadblocks for discussion DTMT NETWORK KOLKATA North-East gears up to meet cancer challenge DTMT NETWORK T IN D IA Drumsticks – a veggie and potential antidote to cancer sexual assault by persons. Do not leave your drink unattended at any time. This provides the perfect opportunity for someone to add hard drugs that could knock you out and place you at risk of sexual abuse. If you feel extremely drunk after only a few drinks, get help because you may have been drugged. Two other predator drugs being used are ‘roofies’ and GHB. These make you feel drunk after 20-30 minutes of consumption. They can also cause amnesia and unconsciousness for three to eight hours. Because of the physiological and psychological effects of alcohol consumption, it is important to know how to administer first aid to an intoxicated person. The following are some guidelines if a problem develops. There is no way to sober up quickly: a cold shower, black coffee, oxygen or exercise only result in a wet, wide awake or tired but intoxicated person. The amount of alcohol in the blood is controlled by the metabolic rate of the liver. Quitting alcohol for short periods – even up to a month – not just brings health benefits but also changes the person’s mindset about drinking, which over time could be a bigger gain. Abstinence not just reduces levels of liver fat, cholesterol and blood glucose but also makes it easier for people to say no to alcohol or to start an evening off with low alcohol drinks. Taking safety steps during festival may save you from accidents caused by excessive alcohol consumption. EAS BS RAWAT the best available scalable models. “In India, public healthcare is much more affordable as compared to the private healthcare; however the lack of physical reach and other practices makes private healthcare system a better alternative. Government of India’s initiatives such as formation of High Level Expert Group (HLEG) on Universal Healthcare Coverage (UHC) and Prime Minister’s announcements about increasing public funded supply of the free generic medicines to the less privileged half of the population by 2017 are some of the steps in right direction,” said Manoj Jhalani, Joint Secretary, Ministry of Health and Family Welfare. “Although substantial progress is visible in the key healthcare indicators, there are still a set of challenges to work upon for improving access to common Indian and guarantee their healthcare needs,” said Bhaskar V Iyer, chairman of Assocham National Council on Drugs and Pharmaceuticals. “At present, socio-economic conditions of Indian healthcare system is in need of innovative models of healthcare delivery. Some models have emerged in the last few years which aim to address issues of accessibility, affordability and assurance on quality of care,” added Iyer. The objectives and major areas of focus of the summit included scaling up best practices, major policy gaps and possible solutions, redefining role of private sector in healthcare, importance of traditional Indian health practices, utilisation of ICT in enabling healthcare delivery and management, pioneering models for increasing access to healthcare and value of a comprehensive health insurance policy to serve health needs of the people. Medical Nation DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Under panic attacks? Don’t panic, beat the blues ROHIT KUMAR In today’s hectic lifestyle people are left with hardly any time for themselves. In this age of cutthroat competition social interaction and family life which gives an individual relief from day-to-day stress have no place in a person’s scheme of things. Anxiety and mental stress are the byproducts of this professional strain which eventually leads to panic attacks. nWhat Are Panic Attacks? Sudden surge of overwhelming anxiety and fear is known as panic attack. In the state of panic attack, heart pounds and breathing becomes heavy. One feels as if he is dying or going crazy. If left untreated, these panic attacks can lead to panic disorder and other problems. They are likely to force us to withdraw from normal daily routine. Panic attacks generally give a sense of unreality or a fear of losing control. In the struggle for success in professional life each individual finds himself or herself alone in life. This takes a toll on physical and mental well-being. Those who have experienced panic attacks think they are having heart attacks, losing their control or even may think they will die. Panic attacks are unpredictable. One can’t anticipate when and where such attack will occur. They can occur even during sleep. An attack generally ends within 10 minutes, but some symptoms may last longer. n What Causes Them There is not a single cause of panic attacks. However, psychological factors like depression, drug abuse and alcoholism are the main reasons for panic disorder. These disorders need to be treated separately. The main symptoms of depression are feelings of sadness or hopelessness, not sleeping adequately, weakness and difficulty in concentration. Patients with Depression can be treated with anti-de- New IVF technique holds out a ray of hope for issueless couples JIVIKA MITTAL NEW DELHI netic abnormalities caused due to abnormal sperms. PGS (pre-implantation genetic screening) is a revolutionary technique that uses array CGH (Comparative Genomic Hybridization) which can screen all the 24 chromosomes for any genetic abnormality and hence is an accurate test to increase the ongoing pregnancy rate. The first of its kind, Iviomics lab, offers the international technology for a safer, faster and more accurate method of identification and selection of healthy, disease-free embryos to overcome the current limits of pre-natal genetic testing. Dr Nalini Mahajan, Past President Indian Fertility Society (IFS) and Clinical Director, Nova IVI Fertility Delhi, said, “Using PGS technology, we selected a chromosomally normal and healthy embryo for transfer to Pooja’s uterus and it resulted in a successful Limited access to contraceptives for Haryana women DTMT NETWORK CHANDIGARH The Punjab and Haryana High Court on Friday directed the Centre and Haryana Government to respond within a month to a petition alleging that the state’s health policy and programmes discriminated against women by limiting information and access to modern contraceptives. The directions came from a division bench comprising chief justice Sanjay Kishan Kaul and justice Arun Palli, while disposing of a public interest litigation (PIL) filed by Rohtak based non-government organisation (NGO) Himmat Mahila Samooh. The petitioner had accused the Haryana government of providing women limited access to reproductive healthcare facilities, inadequate and incorrect information about contraceptives in violation of the National Rural Health Mission (NRHM) and Adolescent Reproductive Sexual Health (ARSH) Strategy. It was submitted that inadequacy of such facilities led to mental and physical anguish with unwanted pregnancy and increased the need for unsafe abortion. The organisation had in November 2013 submitted a similar representation to the Union Ministry of Health and Family Welfare and Haryana Government, but got no response till filing the petition. The court observed: “The petitioner has sought to raise an important issue of adequate healthcare facilities for family control.” It directed the Centre and Haryana Government that they “must examine the issue on the basis of material set out in the petition” and “take a considered decision”, and a speaking order be communicated to the petitioner within a month. Petitioner’s advocate, Veena Kumari, submitted that in a Jindal Global Law School study in 2013 in Haryana, it was revealed that nearly 86 per cent unmarried women did not know about modern contraceptive options. “Inadequate access to modern contraceptives... is a human rights violation, and part of the continuum of indignities women in Haryana experience from birth,” said Colin Gonsalves, founder of Human Rights Law Network, which helped the NGO in legal proceedings. The petition has sought that public health facilities be equipped with adequate stock of contraception, and counselling sessions be carried out at anganwadi centres, primary health centres and community health centres. Papaya – one fruit, five health benefits DTMT NETWOK NEW DELHI Papaya is known as ‘fruits of angels’. The fruit is liked by one. But many people are not aware of medicinal properties the fruit boasts of. Doctors recommend papaya as it is digestive, has nutritional value and last but not the least delicious. The best thing about papaya is its availability in all the seasons and is affordable for all. It has immense health advantages and is packed with nutrients. anxiety medications. Cognitivebehavioral therapy, also known as CBT, can also be highly effective in the treatment of panic attacks. CBT may be used alone, or in conjunction with medications. During CBT, the therapist helps the client identify thought patterns that contribute to panic attacks. Once these harmful thoughts have been identified, the clients can then focus on altering their destructive thoughts and learn to engage in more helpful behaviors. n Self-Help Tips Take a break from the monotony and indulge in a hobby, Exercise to work off tension, Relaxation techniques like meditation, yoga and chanting are beneficial, Eat a healthy diet, with plenty of fresh fruits and vegetables, See a physician and especially if physical complaints persist. Shri Shekhar Kunte an embodiment of social service: Sanjeev Pendharkar DTMT NETWORK “For an ardent and selfless social worker, his dedicated service to the society is itself a precious ornament.” With these words Sanjeev Pendharkar, director of Vicco Laboratories, introduced Shri Shekhar Kunte at function held recently at Dadar (Mumbai) by friends, students and well-wishers of Shri Shekhar Kunte’s Institution. “This rare dedication to social service,” he said “reflected in the life and work of Shri Kunte, who he said has accepted social service as a mission of his life.” Sanjeev Pendharkar was chief guest at the function. On the occasion, he felicitated a number of social workers – including Mrs Shalaka Mane, coaching Yoga, Pranayam and Reiky; Dr Pawar rendering free Ayurvedic diagnosis and treatment for their selfless service to humanity. For more than two decades Shri Kunte inspired the young generation through his various social activities. His efforts were instrumental in trans- As eradication of polio is being celebrated in India, Unicef said there is big need to make immunisation system for children stronger, accessible and tackle the women’s status if it really wants to address the problem of mortality among children. Unicef pointed out that routine immunisation for kids in parts of the country is still very low and they are facing inequality within one state. “Routine immunisation in some parts of the country is yet very low. I visited some districts in south UP where it is below 20 percent. So that’s quite serious,” Louis-Georges Arsenault, Unicef representative to India, said. Though the national average is ”not very bad”, he added. He also alerted that there should be no quite period in polio immunisation programme, which he termed an “amazing accomplishment”, as the danger of polio virus being spread into India from affected parts of the world remains. Polio transmission has not been eradicated Book your worldwide as it was planned and advertisment today!!! danger is as high as it has never been for polio cases to be imCall us at 9971995818 or ported into InWrite to us at — [email protected] dia, he said. Increase your business prospects upto 100% Sanjeev Pendharkar giving away awards to social workers at the function forming the youth from pessimism to optimism and enthusiasm. “He has also developed a team of such social workers roping his his numerous pupils. The society will remain grateful to Shri Kunte and contribute to his remarkable but tough mission.” With these words Shri Pendharkar concluded his speech. Shame of Bihar: Fifth acid attack in just 14 months DTMT NETWORK PATNA Acid attack on a young woman in north Bihar hospital is the fifth recorded case in the state in the past 14 months. The attack came just over six months after the Supreme Court directed state governments to put in place stringent measures to curb such attacks. The victim of acid attack is fighting for her life in the Sri Krishna Medical College Hospital (SKMCH) in Muzaffarpur. She was found in a serious condition at a public place at Mohanpur village under Piprahi police station of Sheohar district before rushed to the hospital. RK Mandal, Piprahi police station house officer, confirmed that a woman was found in a critical condition at Mohanpur. “Out of purely humanitar- “We can’t ignore such danger. We should be aware of it and make sure that the measures that are put in place are sustained. The main thing is to ensure that each and every child continues to be immunized for polio,” the Unicef representative said. It is a big challenge for complete immunisation; he said a well-planned system has to be put in across the country. There are some districts and states where immunisation is running well. Some parts of the country have 99.9 percent. South India is doing much better, he said. India will have to improving the statues of women and children, particularly child marriage, as both issues have a larger impact on a child’s survival and development. DTMT NETWORK New Delhi ian consideration, we have rushed her to Muzaffarpur as saving her life was our top priority. We are in the process of instituting a case”, Mandal said. The SHO claimed that an attempt had been made to kill the woman by setting her alight after pouring kerosene on her. “This was the finding at a medical facility where the police took her for first aid”, he said. However, SKMCH superintendent Dr GK Thakur confirmed the woman was the victim of an acid attack. “She has suffered 65 per cent burns and is admitted to the ICU in a critical con- dition. She was brought here in an ambulance, has been registered as an unknown person and does not have any attendant”, said. On January 22, two men had pinned town a Dalit youth, Ranjit Sada, 22, who they accused of being a thief, and poured acid in his eyes. The attack took place in Kishanpur police station area of Supaul in north eastern Bihar. Earlier, in October last year, failing in their attempt to molest a woman sleeping on a Samastipur railway station platform, some miscreants threw acid on her as retribution. She was badly injured in the attack. Also last October, acid was poured on the private parts of a minor boy accused of theft by the owner of kabadi shop in Sohrai locality of Nalanda in south central Bihar. 78,000 infants die of congenital heart disease every year TH IN D IA When Pooja (name changed), 33, a financial analyst and her husband Purav (name changed), a IT professional decided to start a family, they discovered to their chagrin that she could not conceive as Purav had fertility issues. He was suffering from azoospermia, a severe male factor problem where no sperms are produced in the semen. They explored the option of having their own baby through IVF. After two failed IVF cycles and recurrent miscarriages, they gave up the hope of ever having a baby. However, a third and final attempt using PGS screening technology helped in choosing the healthiest embryo for implantation and today she is successfully 6 month pregnant. Like Pooja and Purav many couples these days face repeated miscarriages or problems in conception. They should consider getting a sperm analysis done before any other test as chances are that an abnormal sperm could be the culprit. Infertility experts say that a new test can successfully screen embryos for ge- A new test can successfully screen embryos for genetic abnormalities caused due to abnormal sperms — Experts pregnancy. It has saved the couple’s precious time, effort and money from undergoing repeated IVF cycles while also assuring them of a healthy and safe pregnancy.” Sharing her story, Pooja said, “We wanted a healthy child and didn’t want to take too many chances so we explored the option of undertaking the new test during IVF (In vitro fertilization). Finally we can look forward to our family being complete. ” Severe Male Factor is a very crucial element that plays a huge role in defining an IVF success rate. About 50% of the infertility cases either alone or in combination with other factors that are evaluated and under treatment are because of the same. It includes not just the abnormal (low) sperm count but also abnormal motility, appearance and volume. Men with a severe male factor problem can produce defective sperms having abnormal DNA. If such a sperm is used for embryo formation, it can form chromosomally abnormal embryos, which if transferred in the mother can lead to failure of implantation and abortion. pression medicines, meditations and physchoterapy. n Signs & Symptoms Some symptoms of panic disorder are: fast heartbeat, chest pains, stomach upset, dizziness, sickness, difficulty breathing, a sense of feeling smothered, tingling or numbness in the hands, dreamlike sensations or perceptual distortions, a need to escape, fear of losing control and doing something embarrassing, fear of dying, terror- a sense that something unimaginably horrible is about to occur and one is powerless to prevent it. n Treatable Medications are often used to treat panic disorders and have been shown to be both safe and effective. The pharmacological treatments that are prescribed by doctors and psychiatrists include antidepressants and anti- Unicef: Vaccination programme for polio needs to be robust NOR 10 DTMT NETWORK AGRA Nearly 78,000 infants suffering from congenital heart disease die in India every year due lack of healthcare facilities, say experts. Congenital heart disease is a problem with the heart’s structure and function that is present at birth. “Every year 1.5 lakh infants are born in India with congenital heart disease,” Dr Murtaza Chisti, chief cardiac surgeon of the Mahatma Gandhi Cardiac and Critical Care Centre said after conducting a medical camp. Due to lack of knowledge among people, cases of congenital heart disease are growing in the country. Work-related stress coupled with lifestyle changes of youngsters and those who belong to 30 to 40 years age group make them susceptible to heart attacks,” he said. “A balanced diet with minimum fatty and nonvegetarian food, non-consumption of sweets, could decrease the growing cases of cardiac related problems, he said, adding that diabetes, high blood pressure, depression, increase in cholesterol were causes of cardiac attacks. Dr ML Swarankar chairman of the India Education Trust, asserted that India had the dubious place of having the largest number of deaths in Asia from heart attack. A new research shows that sharing your anxiety with people who may be feeling the same way, can be an effective coping mechanism to deal with stress. At long last, neonatal screening facility for ESI beneficiaries JIVIKA MITTAL GHAZIABAD Some of the benefits of this tasty fruit are: 1. Some researches in the past have suggested that it is an amazing option of food for diabetic patients as it helps lower blood-sugar levels. 2. It helps in losing weight as they are packed of vitamins, minerals content and does have low calories. 3. Papaya highly advised in constipation, indigestion, heart burn and irritable bowel syndrome as it contains antiamoebic and anti-parasitic traits thereby easing bowel activities. 4. It is also used for skin, pimples and spots. 5. Taking a papaya daily can increase the immunity a lot as it contains Vitamin A and C. ESI hospital, Sahibabad, is soon going to start Gestational diabetes mellitus screening (diabetes screening test for neonates) and the cervical cancer screening for female patients. Dr Vinod Kumar, Medical Superintendent, ESI hospital, Sahibabad, says that they were planning to start these screening tests with the starting of the New Year. But, there are many doctors in the hospital who are on contract basis, and the renewal of the contract was pending. So, due to shortage of doctors in the hospital, they were unable to start these services in the January. “Now, as the contract of these doctors has got renewed we can now concentrate on the initiation of these services,” he added. The machines which are required for the testing and the screening are already available in the hospital. They just need the authorities go ahead so that they can start the diabetes and cancer screening tests in the hospital. Owing to the high costs of these tests, the poor people could not afford these tests. But as these tests will be free of cost here, the most vulnerable people would be able to get the benefit of the service. Good blood sugar control is important before becoming pregnant, because many women do not even know they are pregnant until the baby has been growing for two to four weeks. High blood sugar levels early in the pregnancy (before 13 weeks) can cause birth defects. They also can increase the risks of miscarriage and diabetes-related complications. High blood sugar levels early in the pregnancy can cause birth defects and also can increase the risks of miscarriage A common problem among the babies of pregnant women with diabetes is a condition called “macrosomia,” which means “large body.” In other words, babies of diabetic women are apt to be considerably larger than others. Sometimes, the baby becomes too large to be delivered vaginally, and a cesarean delivery becomes necessary which leads to many complications. The complications associated with Gestational diabetes can be prevented by early recognition, intense monitoring and proper treatment. 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Medical Nation DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi A familiar episode in tallest woman’s saga BS RAWAT The plight of Siddika Parveen, 26, who was brought to the All India Institute of Medical Sciences (AIIMS) recently for removal of a “giant” brain tumour, reflects India’s embarrassing reality of healthcare in rural areas where many patients do not receive timely treatment because of either poor diagnosis or inadequate access to appropriate treatment. The giant brain tumour responsible for secretion of growth hormones up to 16-18 times above the normal level could have been fixed had she got timely treatment. In the absence of any medical aid the tumour went unchecked and by the time she was 15, she was already six feet tall. “She may not have grown so much if the surgery had been done earlier,” Dr Ashish Suri, professor of neurosurgery and who led the surgical team at AIIMS told DTMT. Tests at AIIMS, where she was brought in November 2013, revealed that Siddika’s levels of growth hormone were nearly 16 times higher than the normal range. Suri has per- TALL ORDER: Siddika Parveen with her father Asafuddin Ahmed in her hometown in West Bengal formed nearly 9,000 brain surgeries over the past 20 years and routinely trains young surgeons in endoscopic neurosurgery, a procedure that helps surgeons avoid making large incisions on the skull. “But the surgery on Siddika was among the most challenging I’ve encountered,” he said. The team removed 90 per cent of the 4cm tumour, leaving behind a tiny portion that Suri said could not be extracted because it was too close to important blood vessels. The residual tumour could be removed through radiotherapy or medication. Siddika Parveen is a resident of Buniadpur, about 60km from Balurghat in South Dinajpur, in West Bengal. Her sight was also weak and she was bed-ridden due to fractures in her vertebrae from the last 15 years. Her illiterate parents didn’t know how to help her, so she was forced to live a life of isolation, with no friends and no hope of a future. For Siddika, her height, which earned her the distinction of being the tallest woman on earth, was cause for more pain than joy. AT 26, she measures 7 feet 8 inches and weighs about 130 kilograms, with a shoe size of 15-16. The pituitary adenoma had begun growing when Siddika was in her early teens. Her family recalled that she began grow- ing unusually fast after she had turned 10. Siddika was admitted to AIIMS with a condition where her serum growth hormone level was significantly elevated as a consequence of over secretion of the hormone by the pituitary tumour. Siddika also had a vertebral spine fracture and could not walk properly. Now the tumour is almost gone, but she won’t lose her title of one of the world’s tallest women. First, she spoke no language other than Bengali and we needed an interpretor to create a rapport with her and convince her for the operation, explained a professor who was in the team. Siddika had received pre-operative medical management at the AIIMS endocrinology department and doctors say she will need to continue taking medicines after surgery. “She’ll require lifelong medical therapy to address certain hormone deficiencies caused by the destruction of the normal pituitary gland by the tumour.Siddika’s father Asafuddin Ahmed said she was looking forward to going home. Govt helpless as tobacco goes on a killing spree The rising death toll due to tobacco-related diseases is a matter of grave concern. A World Lung Foundation report has claimed that more than one million people die in India due to use of tobacco products. There are approximately 120 million smokers in India. According to the World Health Organization (WHO), India is home to 12 per cent of the world’s smokers. Tobacco in India is the primary cause of cancer while chewing tobacco Tobacco in India is the primary cause of cancer while chewing tobacco is directly related to oral cancer that affects any part of the oral cavity is directly related to oral cancer that affects any part of the oral cavity, including the lips, upper or lower jaw, tongue, gums, cheeks, and throat. “It is estimated that our oral cancer wards point to 80 to 90 per cent of preventable cancers of the neck, head and throat are tobacco related. The burden of oral cancers caused by chewing tobacco, as well as lung and other cancers caused by smoking tobacco in ‘bidis’ and cigarettes, is Prenatal Sex Determination DTMT NETWORK JAIPUR With a view to curb sex determination and female feticide in the society the preconceptions, prenatal diagnostic technique (PCPNDT) cell of the health department here has come up with a novel initiative. Now, pregnant women will assist in decoy operations to nab doctors and their agents involved in prenatal sex selection activities. In this context the department even gave a proposal to the Government on rewarding the pregnant women who volunteer to play decoy to the doctors with a cash prize as incentive. In fact, the health department is already carrying out such operations to nab the culprits but is finding it difficult to take the help of pregnant women in the absence of a cash incentive which could encourage. Under the Mukhbir Yojna, the state Government gives Rs 1 lakh as reward to any person who gives information to the PCPNDT cell and helps in decoy operation to nab the persons involved in sex selection activities. Help of a pregnant woman is always needed in decoy operation. The Health Department and the mukhbir (whistle blower) send a pregnant woman as a decoy to the doctor suspected to be involved in prenatal sex determination activities. In most cases the mukhbir persuades a pregnant woman for the operation and it is his responsibility to reward her. After successful decoy operation, the mukhbir gets Rs 1 lakh in instalments, which depends on the case filed in the court against the doctor too. So far the Department has not taken an initiative to reward the pregnant women directly as mukhbir rewards her from the Rs 1 lakh that he gets from the department. It depends on the mukhbir how much money he parts with as a reward for her. A Health Department official said that they have now impressed upon the state Government on the need to reward pregnant women under Mukhbir Yojna. PCPNDT cell has proposed that the amount should be increased to Rs 2 lakh so that it can be shared between the mukhbir and the pregnant women. Timely innovative surgery averts stroke successfully DTMTNETWORK NAGPUR A special surgical intervention and welltimed treatment at the Orange City Hospital and Research Institute prevented a dangerous situation like stroke in a 65-year-old man. Hospital authority claimed that this is the first time a procedure of this kind was carried in Nagpur. The patient came to the hospital with slurred speech and some problem in the right eye vision, which if picked in time can avert brain stroke and save a man’s life. “The patient had typical indications of the danger ahead and fortunately for him the doppler picked up the 70 per cent block in the carotid artery, the artery in neck which supplies blood to the brain. Had it been not cleared in time, the block would have caused to a brain stroke,” said Dr Anup Marar, medical director of OCHRI. “There are many ways of clearing the block in carotid artery. One of the common methods is angioplasty (an operation to repair a damaged blood vessel or unblock a coronary artery) in the block area. But there are many disadvantages of the process, including the cost. In the modern era carotid artery stenting, still carotid endarterectomy ( a method of cleaning the block surgically) or CE remains the gold standard. So, we decided to use this technique against angioplasty,” said Dr Rohit Gupta a vascular surgeon who performed the surgery. I ST N D IA Pregnant women to be rewarded for catching doctors red-handed enormous,” said Pankaj Chaturvedi of Tata Memorial Hospital, Mumbai. Earlier, a report by the International Tobacco Control Project has stated that despite having signed a global treaty on tobacco control and having numerous antitobacco and smoke-free laws, India has failed to implement them completely. “Health experts are surprised at the rising incidence of cancer caused by lifestyle factors, particularly tobacco use. Governments must implement policies on an urgent basis to prevent the access of unhealthy products and enforcement of ban their advertisements and promotion,” said Nandita Murukutla, India director of World Lung Foundation. WE DTMT NETWORK The blockage in the carotid artery was originally leading to discharge of some of the deposited cholesterol moving randomly once in awhile upwards in the brain. Depending on the area of brain where these pieces were moving, the patient was responding accordingly. Therefore the person’s speech and vision were affected. The patient responded extremely well and regained his speech and vision after the surgery. Otherwise also, the slurring of speech and loss of vision in such case is a temporary phenomenon. But if the patient is aware and sees the he can be diagnosed and a brain stroke can be prevented. Whether this patient had knowledge of the symptoms is unclear but he came to the doctors in time and therefore was saved of the stroke. Health issues plague auto drivers DTMT NETWORK NAVI MUMBAI Years of auto driving tells on health of the drivers in the city. This was disclosed in a free health camp organised by a city hospital. Poor vision, back pain and painful mobility of wrists were the major problems found among them. Out of 130 auto drivers in the age group of 20-40 who attended the health camp at Sneh Saideep (SSD) hospital, Koparkhairane, a significant 81 or 62.3 per cent reported ophthalmic and orthopedic prob- Health problems were high among auto drivers in their 40s, who had begun driving when they were in their 20s lems. Eight of them even have high levels of blood sugar. “We had anticipated more bone problems, but eye tests showed auto drivers have major vision issue and they had no knowledge of it. Thirty-five relatives of the auto drivers who went through a checkup also suffered from eye problems and joint pain,“ said Dr Sandeep Thadani who heads the operations department at the hospital. He said, “Health problems were high among auto drivers in their 40s, who had begun driving when they were in their 20s. This was the first health check-up camp for auto drivers as they serve as in reaching hospital during emergencies.” “Two auto drivers have undergone eye operation and those who suffered from bone problems have been advised regular exercise,” said Dr Thadani. 11 ‘High-caffeine’ drinks may lead teens to drugs Mandatory eye tests mooted for diabetics DTMT NETWORK AGRA The government must make eye tests mandatory for diabetic patients to prevent increasing blindness in India, a leading doctor recommended an ophthalmology convention that ended here on Sunday. Quresh Masketi, president of the All India Ophthalmologiacal Society, made the suggestion at the four-day meet, a conference spokesman said. Due to lack of awareness, many diabetic patients are losing eye sight and making their lives difficult as their eyes were not checked regularly. A total of 6,000 delegates from different parts of the country participated in the convention, the world’s largest gathering of eye surgeons and eye care specialists. The conference discussed new techniques, evaluated the performance of latest gadgets and shared useful professional experiences. More than 220 scientific papers were discussed, the spokesperson said. HP Singh, a important of the organising committee said, “ Both for the country and Agra, this has been a truly landmark conference. Rohit Kumar Children who consume high-caffeine energy drinks may indulge in using alcohol, cigarette, or drug, a new study has claimed in US. The same characteristics that attract youngsters to consume energy drinks such as being different or riskoriented may make them more likely to use other substances as well, suggests the new search by Yvonne M. Terry-McElrath, MSA, and colleagues of the Institute for Social Research, University of Michigan, Ann Arbor. This research was done on nearly 22,000 US secondary school students. Responding to questions about 30 per cent children said they use caffeinecontaining energy drinks. More than 40 per cent said they take regular soft drinks every day, while 20 per cent drank soft drinks daily. It was revealed that boys were more likely to use energy drinks than girls and teens were in large numbers using it without parents at home and those whose parents were less educated. Surprisingly, the children whose ages were 11 to 13 were most likely to use energy drinks. Students who used such energy drink or caffeine related items were more in possibilities in using alcohol, cigarette or illicit drugs. Women may be at higher risk of stroke than men, warn scientists Rohit Kumar US scientists have warned for the first time that women may face a higher risk of stroke then men due to high blood pressure, disorders in pregnancy and other hormonal changes. American Heart Association issues guidelines for preventing stroke in women tells factors such pregnancy, birth control pills, and migraine headaches with aura and menopause that put women at particular risk for stroke. “If you are a woman, you share many of the same risk factors for stroke with men, but your risk is also influenced by hormones, reproductive health, pregnancy, childbirth and other sex-related factors,” said Cheryl Bushnell, author of the new scientific state- ment. The guidelines said that high blood pressure, migraine with aura, artial fibrillate, diabetes, depression and emotional stress factors that are likely to be stronger or more common in women than in men. According to new guidelines, Women have basically a history of high blood pressure before pregnancy should be considered for low-dose aspirin and cal- cium supplement therapy to decrease preeclampsia ( abnormal condition of pregnancy characterized by hypertension and fluid retention, albuminuria) risks. Women who have preeclampsia have twice the risk of stroke and a four-fold risk of high blood pressure later in life. That’s why, preeclampsia should be known as a risk factor too after pregnancy, and other risk factors like high cholesterol, obesity, smoking in such type of women should be treated early, the association said. Pregnant women with slightly high blood pressure may be considered for blood pressure pills, whereas expectant mothers with extremely high blood pressure should given proper treatment. Medical Latest 12 Premature birth can have Common cold: long-term health effects Drug promises DTMT NETWORK NORTH CAROLINA A new study published journal PLoS One indicates that a major cause of premature birth - where waters break too soon, triggering labour may be caused by specific bacteria. This research could lead to screening and possible treatment for women at risk of early labour and help and protect the newborn from further difficulties. The condition wherein the water breaks prematurely in a pregnant woman is termed as preterm premature rupture of the membranes (PPROM). It is estimated that nearly one-third of all premature births are caused due to early rupture of membranes. The membranes that make up the sac that holds the baby usually break at the start of labour. The study was conducted by the researchers at the Duke University School of Medicine and has found that high numbers of bacteria are present at the site This discovery will help prevent premature births by detecting bacteria associated with premature rupturing of the membranes where membranes rupture which are linked with the thinning of membranes. It is important to understand that if the bacteria are the major cause of early membrane rupture, then this study may lead to new treatments or screen for women at risk. This discovery will help prevent premature births as certain bacteria associated with premature rupturing of the membranes can be detected by screening early in pregnancy and treated affected with antibiotics and thereby reduce risk for PPROM. Still following the research more opportunities are required to explore potential targeted therapeutic interventions in the field. surefire cure DTMT NETWORK LONDON UK scientists have found a new drug compound which can prevent people from catching the cold virus by blocking its transmission to others. The very same compound can also be useful against potentially dangerous illnesses as polio, hand, foot and mouth disease, which have caused thousands of deaths globally. The work of this compound is to bind itself to the virus, paralyzes it and prevents it from releasing the genetic material that causes the infection. Presently, there are number of effective drugs against the flue, but drugs which can ward off diseases like common, cold polio and hand, foot and mouth disease are not available, said Dave Stuart, lead researcher from the University of Oxford. He said this compound can also help improve polio vaccines. Medicine alone can’t beat cancer; prevention is vital, says WHO DTMT NETWORK On World Cancer Day on February 4th, World Health Organization asserted that drugs alone can’t cure or protect from cancer but using of better vaccines and preventive public health policies are required to fight against the fatal disease. Noting that the dreaded disease is growing “at an alarming pace”, WHO’s International Agency for Research on Cancer (IARC) stressed on the need for new measures to curb the menace. Scientists from more than 40 countries take part in producing IARC report roughly once in five years. They said that more commitment and dedication is needed to fight cancer. They said relatively effective and inexpensive drugs would significantly drastically cut death tolls even in places where healthcare services are less developed because a large number of patients can’t afford the treatment. According IARC report, in 2012, the number of cancer cases were 14 million which is expected to rise to 22 million. Over the same period cancer deaths are likely to rise from 8.2 million a year to 13 million per year and that would be hard to overcome if it continues with this pace. The data also suggests that at the present rate one in five men and one in six women will develop cancer before they attain the age of 75 years and one in eight men and one in twelve women will die from disease. In 2012, the most common causes of cancer deaths were liver, lung and stomach cancer. Increasing and aging population in developing countries will be affected the most by cancer cases. 60 per cent of cases take place in Africa, Asia, Central and South America. This regions account for 70 per cent of cancer deaths and the condition becomes so critical when such deaths or tragedy occurs in poorer countries due to lack of health facilities. “Governments must show political commitment to implement the high-quality screening and early detection programs, which are an investment rather than a cost,” said Bernard Stewart, another co-editor of the report. DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Human lungs grown in a lab for the first time DTMT NETWORK Researchers at the University of Taxes Medical Branch in Galveston of the US have succeed in growing human lungs in the laboratory using components from the lungs of deceased children. Stem cell (undifferentiated biological cells) specialists have been working on growing lung tissue for some years, but the lung is a complex organ of the body, which gives more troubles than renewing other organ tissue, such as human skin. The University of Texas Medical Branch first announced their solution for growing lungs in 2010. “The lung is probably the most complex of all organs – the cells near the entrance are completely different from those deep in the lung,” UTMB researcher Dr Joaquin Cortiella. “People question us why we are doing the lung, because it is so difficult. But the potential is so great, and the technology is here. It’s going to take time, but I think we’re going to make a system that works,” he said. “If we can make a good lung for people, we can also make a good model for in- At long last, effective HIV vaccine comes closer to reality DTMT NETWORK Washington to human lungs. Taking lungs from two children who were killed in an accident, the researchers stripped one of the lungs down to a bare skeleton of just collagen and elastin – the main proteins in connective tissue. Using this stripped-down lung as a “scaffold”, they harvested cells from the other lung, which were applied to the scaffolding. This lung structure was then placed in a chamber filled with a nutritious liquid. After four weeks of immersion, the team removed a human lung from the liquid. It was just softer, pinker and less dense. The team then successfully repeated the process suing a second set of lungs. jury. We can make a fibrotic lung and assess what’s happening with those, what the cells are doing, how well stem cell or other therapy works,” researcher Dr Joan Nichols said, adding, “We can see what happens in pneumonia, or in tuberculosis, or hantavirus - all the agents that target the lung and cause damage in the lung,” he added. The research conducted in 2010 involved destroying rat’s cell by repeatedly freezing and thawing and then reseeding the lungs with developing stem cells from pests. Following that work up with similar but more largescale experiments on pig lungs, the researchers now applied the same regenerative engineering principles Scientists have discovered a mechanism that helps HIV evade antibodies and stabilise key proteins, a finding that could pave way for more effective vaccine for the deadly virus. National Institutes of Health (NIH) scientists found the mechanism involved in stabilising key HIV proteins and thereby concealing sites where some of the most powerful HIV neutralising antibodies bind. Numerous spikes jut out of the surface of HIV, each containing a set of three identical, bulbshaped proteins called gp120 that can be closed together or spread apart like the petals of a flower, researchers said. Some of the most important sites targeted by HIV neutralising antibodies are hidden when the three gp120s, or the trimmer, are closed, and the gp120 trimer remains closed until the virus binds to a cell, they said. The researchers discovered that certain amino acids located on the gp120 protein undergo a process that stabilises the trimer in its closed position. In this process, called sulfation, the amino acids acquire a sulfur atom surrounded by four oxygen atoms. By either blocking or increasing sulfation of these amino acids, the researchers changed the sensitivity of the virus to different neutralising antibodies, indicating that the trimer was being either opened or closed. The scientists suggest that if the synthesised gp120 widely used in HIV research were fully sulfated during manufacture, the resulting product would adopt a more true-to-life structure and more closely mirror the way the immune system sees unbound HIV. This might help generate a more effective HIV vaccine, NIH researchers said. They added that full sulfation of gp120 may enable scientists to crystallise the molecule more readily, which also could advance HIV vaccine design. Turning down thermostat can help lose weight: Study DTMT NETWORK A research suggested that turning down thermostat a few degrees could help reduce weight O verweight people can be found in all age groups and sections of the society. Obesity is not a disease in itself, but it gives rise to many a medical condition. In some cases obesity causes depression among youngsters. Here is good news for those who are looking forward to cut down that extra flab in their bodies. Dutch research has claimed that keeping temperature a bit cool at home may help reduce weight during winters. It burns calories to keep you warm. Americans love to crank up the thermostat particularly in bitterly cold conditions. But a new research suggested that turning it down a few degrees could help to reduce weight. “Since most of us live in indoor conditions 90 per cent of the time, it is worth Crossword Hints cal order? (7) 2) Appropriate work in bed (5) 1) Getting back bit in Radio Te- 3) Whip up perfume (7) lephony for evidence of pay- 4) Conducts tense incomplete ment (7) search before Tuesday, the 5th of August (9) 5) A legendary musician, he joins us after turning profes 5) Readily available, like piped sional (7) water (2,3) 9)Watch for order containing 6) Boat for Landseer, perhaps (7) fifty boxes with arrows (9) 7) Unnecessary oath from ex- 10)Simply missing the point, I priest I’ve allowed in earlier (9) suggest (5) 8) Statements, perhaps more 11)Former prongs may furnish than one saw (7) outer coats (7) 14)Famous lover partly emraced 12)The sound of raindrops -- by Maria could knock you last thing in design for a down (9) model (7) 16)Victor William? (9) 13)Monsieur drowned in unspe- 17) Quietened when learner ci fied French river (5) bungled around (7) 15)Right after two cop per bits 18)Skill is extremely troulesome for gourds (9) for a performer (7) 17)Evil, it’s normal, possibly 19)He is not doing it for money; (6,3) a good friend coming to an- 19)Proficient in algebra, starting cient city (7) with short division (5) 20) See tidy artful batiks! (3-4) 21)Juliet and I invested in suet- 22)Dismisses dry white wines (5) like snacks (7) 24)Jetsons dog star? (5) 23)United Nations leads a war, with Eritrean head caught napping (7) 25)Mendacious storytellers? (5) 26) Confine bear without a trade (9) 27)Merchants could be card players (7) 28)Umpire Southhead surrounding jumper pro- vides shelter again (7) Across Down 1) Beams in reverse alpha beti- Solution on page 16 exploring health aspects of ambient temperatures,” lead author Wouter Van Marken Lichtenbelt said. “What would it mean if we allow our bodies to work again to control body temperature?” Lichtenbelt and his team has been working on this for 10 years. Animals and humans shiver to stay warm. There are types of shivering, one of them called thermo genesis occurs when the temperature is cool but not cold, says research. That type of shivering is called ‘brown fat’ that can burn up to 30 percent energy of the body and help to reduce weight loss. Brown adipose tissue (BAT), also known as brown fat, is one of two types of fat humans and other mammals have – the other type is known as white or yellow fat. Human newborns and hibernating mammals have high levels of brown fat. Brown fat’s main function is to generate body heat. However, scientists are just starting to understand what brown fat does, and stress that there is a great deal about it that we do not yet know. Brown fat was discovered in adults in 2009 which burns calories instead of storing them like white fat. Amazing Facts Most people think of the toilet as the most contaminated part of the house, but in fact the kitchen sink typically contains 100,000 times more germs than a bathroom or lavatory. The human body is home to some 1,000 species of bacteria. There are more germs on your body than people in the United States. Trachoma, the leading cause of preventable blindness worldwide, is related to the lack of facial hygiene. When you are looking at someone you love, your pupils dilate, and they do the same when you are looking at someone you hate. The human brain cell can hold five times as much information as the Encyclopedia of Britannica. Your body gives off enough heat in 30 minutes to bring half a gallon of water to a boil. Each year about 2,500 people go to emergency rooms to be treated because of injuries caused by using a toothbrush. On an average, women say 7,000 words per day. Men speak just over 2,000. The eye of a human can distinguish between 500 shades of gray. Sudoku Corner How to play Fill in the grid so that every horizontal row every vertical column and every 3 x 3 box contains the digits 1 to 9, without repeating the numbers in the same row, column or box. You cant change the digits already given in the grid. Every puzzle has one solution. Medical Globe DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi 13 Decoded: How brain creates sequences in the memory DTMT NETWORK LONDON We would further study the functional organization of the basal ganglia during learning and execution of action sequences,” Rui Costa said. ‘A step closer’, according to Nature article N euroscientists have discovered how efficiently the brain organises memories and actions by connecting separate small elements to become a unique and meaningful sequence. “A specific area of the brain – the basal ganglia – is involved in a mechanism called chunking that signals neurons to connect individual elements into a behavioural sequence, says a study published in the journal Nature Neuroscience. “We trained mice to perform gradually faster sequences of lever presses – similar to a person who is learning to play a piano piece at an increasingly fast pace,” narrated Rui Costa from the Champalimaud Neuroscience Programme (CNP) in Lisbon, Portugal. “By recording the neural activity in the basal ganglia during this task, we found neurons that seem to treat a whole sequence of actions as a single behaviour,” he added. The basal ganglia encompass two major pathways, the direct and the indirect. The authors found that although activity in these pathways was similar during the initiation of movement, it was rather different during the execution of a behavioural sequence. “The basal ganglia and these pathways are absolutely crucial for the execution of actions. These circuits are affected in neural disorders, such as Parkinson or Huntington’s disease, in which learning of action sequences is impaired,” added Xin Jin, an investigator at the Salk Institute in San Diego, US. “We would further study the functional organization of the basal ganglia during learning and execution of action sequences,” Rui Costa said. ‘A step closer’, according to Nature article. Scientists have found a way to turn animal cells back to a youthful, neutral state, a feat hailed as a “game-changer’’ in growing transplant tissue. The research, reported in the journal Nature, could be the third great advance in stem cells - a futuristic field that aims to reverse Alzheimer’s, cancer and other crippling or lethal diseases. The latest breakthrough comes from Japan, as did its predecessor which earned its inventor a Nobel Prize. The new approach - provided it overcomes safety hurdles - could smash cost and technical barriers in stem-cell research, said independent commentators. “If it works in man, this could be the game-changer that ultimately makes a wide range of cell therapies available using the patient’s own cells as starting material,’’ said Chris Mason, a professor of regenerative medicine at University College London. “The age of personalised medicine will have arrived.’’ Stem cells are primitive cells that, as they grow, differentiate into the various specialised cells that make up the different organs - the brain, the heart, kidney and so on. The goal is to create stem cells in the lab and nudge them to grow into these differentiated cells, thus replenishing organs damaged by disease or accident. One of the obstacles, though, is ensuring that these transplanted cells are not attacked as alien by the body’s immune system. To achieve that, the stem cells would have to carry the patient’s own genetic code, to identify them as friendly. Sunanda latest victim of drug overdose among rich & mighty DTMT NETWORK NEW YORK Socialite Sunanda Pushkar Tharoor was found dead after a heated exchange on Twitter where she alleged that her husband was having an affair with a Pakistani journalist. Her body was discovered by husband Shashi and the autopsy report suggested that she died of a drug overdose – most probably a combination of sedatives and strong medicines. Sunananda is not the lone celebrity to have died of substance abuse. In fact, there seems to be a causal link between fame and substance abuse which more often than not ends on a tragic note. Here is a list of rich and famous whose deaths under mysterious circumstances caused flutter in the society. nPhilip Seymour Hoffman Philip Seymour Hoffman recently died of an alleged heroin overdose. He’s not the first celebrity whose death is linked to substance abuse. n Cory Monteith The Glee star was found dead in his Vancouver hotel room after taking a lethal cocktail of heroin and alcohol. He was alone when he died. n Anna Nicole Smith The former Playboy model and reality TV star was found unresponsive in a hotel in Hollywood and when she was rushed to a hospital she was declared dead. Her death was caused due to a combination of drugs but the major culprit was chloral hydrate – a sleep drug. n Marilyn Monroe Hollywood’s ultimate sex symbol was discovered dead in her bedroom by her psychiatrist and it was believed she committed suicide by consuming too many anti-depressants. Her cause of death was believed to be ‘acute barbiturate poisoning’ though many still consider the circumstances suspicious. n Heath Ledger Heath Ledger will forever be remembered for his immortal portrayal of The Joker in The Dark Knight and he even received a posthumous Os- R O F G N I K O LO car for that performance. Many believed that his preparation for the role of a joker might have driven him over the edge and he was found dead a few days after shooting. Autopsy reports revealed that he died of acute intoxication caused due to the effect of six different prescription drugs. n Janis Joplin The legendary musician’s manager found her dead at her house in Hollywood. She too died of a heroin overdose and was found dead with a cigarette in her hand. n Elvis Presley The King of Rock and Roll died of cardiac arrhythmia (irregular heartbeats) and it was believed that it was caused by an overdose of prescription drugs including codeine, valium, morphine, and Demerol. n Jimi Hendrix Arguably the greatest guitarist of them all had a history of drug abuse and was even arrested for possession of heroin in 1969. He was acquitted after convincing the authorities that the drugs were planted in his belongings and he died of a heroin overdose in 1970. n Jim Morrison Drugs have claimed some of music’s greatest talents including the Doors frontman who was just 27 when he was found dead in a Paris apartment bathtub. While there’s no autopsy report to back up this claim, most believed he died of an a heroin overdose, having accidentally injected it believing it to be cocaine. n Kurt Cobain Like Morrison, Cobain too was just 27 when he was found dead. He left behind a suicide note and the autopsy revealed a high concentration of heroin and traces of diazepam (Valium) in his body. n Sid Vicious The bassist from the punk rock band The Sex Pistols died in his sleep after a party. He consumed a lot of heroin on the night after his release from prison and the drug was provided to him by his mother! But it doesn’t always end badly, here are 10 celebs who beat addiction! Delhi Kolkata Mumbai bangalore Hyderabad Chennai Full time/freelance journalists in Delhi, Mumbai, Bangalore, Chennai, Hyderabad & Kolkata for our pan India level English monthly medical newspaper. Science background will be preferred. ‘DRUG TODAY MEDICAL TIMES’ Interested candidates can contact at: (011) 22792554, 22792078 Or E-mail at: [email protected], Website: http://drugtodayonline.com India gifts 17 ambulances to Nepal DTMT NETWORK KATHMANDU India’s ambassador to Nepal Ranjit Rae presented 17 ambulances and four buses to various social and educational organisations during a function to mark the Republic Day in the Indian Embassy premises. The remaining three ambulances were gifted by the Consulate-General of India, Birgunj to various organisations based in southern Nepal. Rae presented books to 50 educational organisations, libraries and training institutions. He hoisted the national flag and read out the address of the President of India, which stressed among other things “India’s support for peace, stability and development in its neighbourhood”. Nepali Congress president Sushil Koirala, general secretary Prakash Man Singh and former prime minister Baburam Bhattarai among others were present on the occasion. Rare Diseases Mermaid Syndrome A young victim of the genetic disorder Sirenomeila (Mermaid Syndrome) S irenomelia is a rarely found disease which affects the development of kidney, urinary bladder, genitourinary abnormalities, gastrointestinal abnormalities and anomalies of the lumbar sacral spine at the initial stage of birth. The disease is a result of failure of normal vascular supply from the lower aorta in utero. In this particular disease most of the infants die. The exact cause of sirenomelia is still not known, most cases take place randomly for no apparent reason. In Sirenomelia, also called as Mermaid Syndrome, legs of the newborn are fused together and look like tail of a mermaid, a half woman and half fish that lives in the sea. This condition is found in nearly one out of 100,000 infants as rare as conjoined twins. Affected infants may have one foot, no feet or both feet, which may be rotated externally. The tailbone is usually absent and the sacrum is partially or completely absent as well. More than fifty percent of such disease results in stillbirth and this may happen to identical twins than in single birth or dissimilar twins. Cases where infants have survived the disease: nA girl from Peru, known as the ‘Little Mermaid”, has taken her first steps after undergoing a second round of surgery to separate her fused legs. Milagros Cerron, now two years old, is learnt to be one of the world’s few surviving ‘Mermaid syndrome’ babies. nTiffany Yorks of the United States underwent successful surgery in order to separate her legs before she was one year old. She is the longest-surviving sirenomelia patient. nShiloh Pepin who has been named as an extraordinary person in the US didn’t have bladder, uterus, rectu, vegina, rectum. She had only six inches of large colon and with only one quarter of a kidney and one ovary survived for ten years. First Indian WHO regional director for southeast Asia BS RAWAT NEW DELHI Taking charge as regional director of WHO for South-East Asia Dr Poonam Khetrapal Singh is the first the first Indian national in particular and the first woman in general to hold the coveted post. She retired as advisor, International Health in the Ministry of Health and Family Welfare. Dr Poonam was elected by the 11 member states of the region in September 2013 and subsequently appointed by the WHO’s executive board at its 134th session in January 2014. The South-East Asia Region is expected to be certified polio free by WHO in March 2014. Dr Poonam Khetrapal Dr Poonam Khetrapal Singh Singh served for over two decades as a civil servant in India as a member of the Indian Administrative Services. She was the Secretary to Health, Family Welfare and Medical Education in the State of Punjab, with a population of 22 million and a health budget of US$ 350 million. In 1987, Dr Singh moved to the Health, Population and Nutrition Department of the World Bank. In 1998 she joined WHO headquarters as executive director, Sustainable Development and Healthy Environments, and a member of the Cabinet of then director-general Dr Gro Harlem Brundtland. From 2000 to 2013, Dr Khetrapal Singh served as WHO deputy regional director for the South-East Asia Region. In February 2013, she joined the Ministry of Health and Family Welfare of the Government of India as Advisor for International Health, where her principal task was to strengthen global health outcomes and provide guidance to the Ministry to take forward the international health agenda. India, Netherlands sign MoU to boost ties in health sector DTMT NETWORK NEW DELHI Indian and the Netherlands signed an agreement to boost bilateral cooperation in the areas of communicable diseases, public health policy, e-health, and medical products among others. Under the agreement, both countries could also encourage greater research collaborations among their universities, foundations, industry and the health services, an official statement said. The Memorandum of Understanding (MoU) was signed by Health and Family Welfare Minister Ghulam Nabi Azad and his Dutch counterpart Edith I Schippers. Azad said the strengthening of cooperation between the two countries would result in mutually beneficial exchanges. “This is a very positive development and a step forward from the sectoral MoU between respective food regulatory authorities in the area of food safety,” he said. Schippers said the MoU would strengthen ties between the two countries in the areas of health. Azad expressed his happiness that the United Nations had recognised the importance of health in the next generation of global development goals beyond 2015, suggesting an illustrative goal of “ensuring healthy lives”. DTMT Exclusive 14 DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi TB – no more formidable, but facing weak resistance Don’t ignore bad cough! Go for a test and make sure it’s not TB JIVIKA MITTAL R With 2-2.5 million cases of tuberculosis reported annually in the country India has achieved a dubious distinction of being home to highest number of TB patients in the world. High prevalence of tb in the country and the casualties at a time when the totally disease is a sad commentary on the state of our healthcare system. Unless we take steps to plug the loopholes in the implementation of healthcare schemes, our victory over TB will remains pyrrhic. eena had bad cough for two months. She was taking cough syrup regularly taking it for bad cold. But there was no respite from cough. As gradually she started having fever with high temperature, losing weight and was complaining pain in the chest, omitting blood, weakness and fatigue she realised something seriously wrong with her. She underwent some test and diagnosed with tuberculosis. Tuberculosis (TB) is a highly contagious disease caused by the bacteria that spread through the air from one person to another. The TB bacteria spread when a person with TB of the lungs or throat coughs, sneezes, speaks or sings. People nearby may breathe in these bacteria and become infected. The TB bacteria usually attack the lungs, but can attack any part of the body such as the kidney, spine, and brain. It is important to note The TB bacteria spread when a person with TB of the lungs or throat coughs, sneezes, speaks or sings. People nearby may breathe in these bacteria and become infected. Normally, the TB bacteria usually attack the lungs, but can also attack any part of the body such as the kidney, spine, and brain that everyone infected with TB bacteria does not fall sick. People who get infected but are not sick have latent TB infection. People who have latent TB infection do not feel sick, do not have any symptoms, and cannot spread TB bacteria to others. But they can be a carrier of the disease. A positive TB skin test or TB blood test only tells that a person has been infected with TB bacteria. It does not tell whether the person has latent TB in- Need to cut down delay India home to most TB patients in the world in treatment of TB cases ROHIT KUMAR BS RAWAT As theme for World TB Day 2014 – “A TB test, treatment and cure for all” – has been announced, global partners will call for an effort to find, treat and cure all people with TB and accelerate progress towards the bold goals to see in Tuberculosis strategies post-2015 and a world with Zero TB deaths, stigma and infections. The day is observed all over the world not only to create awareness in the general public about the disease but also to involve it in the efforts for total eradication of the disease. World TB Day has been established to commemorate the tuberculosis by all at one place in order to get some solution to eradicate it from the world. It mobilises the political and social authorities for further progress towards the disease prevention for the effective reduction in the TB cases and death rate in the coming years. TB is a completely curable disease at very lowcost through the DOTS treatment administered by the government. Its treatments and diagnostic tests should be accessible by each and every person affected by the tuberculosis all over the world. Active participation is required by the all group people, communities and government agencies to work together as it is continues to be major public health threat, with an estimated 8.7 million new cases per year, and an estimated 1.4 million deaths. Early case detection and rapid treatment continues to remain the cornerstone of the “Stop TB strategy”. With the incidence of TB declining very slowly, it is now becoming clear that TB cannot be eliminated by 2050. India has the world’s highest burden of TB where TB kills one person every two minutes and 750 people every day. Global TB control is unattainable without enhanced control of TB in India. The emergence of “totally drugresistant” and the DOTS strategy may not be sufficient for reducing TB incidence in the country. India’s Revised National TB Control Programme (RNCTP) has made great strides in the last decade, and free, quality-assured TB diagnosis and treatment is available to all patients who seek care in the public sector. While there are some positive developments, but the TB control in India is at a critical juncture. The DOTS program has been scaled-up and may have reached its limits because TB incidence is not declining. TB case finding has plateau and many cases remain either undiagnosed. By the time TB cases are initiated on treatment in the RTNCP, they likely have already infected many others in the community. Delays in diagnosis or ineffective treatment lead to ongoing transmission, facilitating the spread of the disease. The government reluctantly made TB a notifiable disease as the public and private sectors were not ready to correct this anomaly and have shown little interest in implementing the order. If implemented in right earnest, every case detected would get reported and the actual extent of the disease will bec o m e known. Of late, there has been a dramatic rise in cases of tuberculosis cases in India. According to World Health Organization (WHO), of a total number of TB cases in the world, 2-2.5 million cases are from India alone. This makes our country the most TB vulnerable nation in the world. Poverty, huge urban settlements and unhygienic living conditions are some of the major factors behind this rise. A rough survey shows that even one unnoticed TB patient could affect 10-15 people in one year. Take the case of Mumbai, in January 2012 the city had a big TB worry when 12 people were reported to be suffering from a totally drug resistant version of tuberculosis, a potential epidemic likely to occur. Cases Undetected One of the important aspects of the report was that the three million TB cases are not detected each year and 33 per cent popula- tion does not get treatment when they need it the most. The WHO believes that if we want to eradicate this dangerous disease, we need to reach such patients. It was estimated that 450,000 people suffered from a multi-drug resistant variety of TB with China, India and Russia accounting for the highest patients. MDR-TB is a type of tuberculosis that can resist the first line of anti-TB drugs. It happens because people do not take medicine regularly or stop taking it mid-way in the course of treatment. It spreads in the same way as tuberculosis. Mdr-Tb Threat The WHO’s belief that drug-resistant TB is a big problem is completely justified as we would be hardpressed to make new drugs if the millions around the world were forced with drug-resistant TB. “The unmet demand for a full-scale and quality response to multidrug-resistant tuberculosis is a real public health crisis,” says Dr Raviglione, head of the WHO’s tuberculosis programme. “It is unacceptable that increased access to diagnosis is not being matched by increased access to MDR-TB care. We have patients diagnosed but not enough drug supplies or trained people to treat them. The alert on antimicrobial resistance has been sounded; now is the time to act to halt drugresistant TB.” Maintain Funding The present worldwide funding to fight TB is nearly $2 billion per year and it is particularly crucial for lowincome countries which heavily depend on international donor funding. To increase response, we will require refilling the Global Fund so that there is decline in the resources handed out to vulnerable nations. The WHO is trying to meet its Millennium Development Goals but it will need to maintain the current pace and to rise in some sectors to reach its goals. fection or has progressed to TB disease. Other tests, such as a chest x-ray and a sample of sputum, are needed to see whether the person has TB disease. Not all people need a TB test. You should get a TB test if you are at increased risk. If a person has been recently infected with TB bacteria or his immunity is decreasing day by day, should undergo the TB tests. While anyone can get TB disease, some people who are infected with TB bacteria are more likely to get sick. The person who has HIV infection can be infected with TB bacteria as well in the last two years of his existence because he will have weak immune system or consumes alcohol and hence have higher chances of getting TB. Active TB disease can be fatal if left untreated, therefore, regular monitoring and treatment by a doctor is crucial as doctor gives several antibiotics to treat the infection and to help prevent resistant bacteria from emerging in patient’s body. Tips for prevention Early diagnosis: Early diagnosis is key to avert spread of the disease and infection. Patients with active lung tuberculosis can go to any government chest clinic for treatment. Close contacts: The close contacts of TB patients, generally members of the household, should be examined. In the examination, skin test and or chest X-ray examination for teenagers and older children and adults are essential. Healthy lifestyle: The germs attack the lungs when a person’s body resistance decreases. So, try to protect yourself by leading a healthy lifestyle in order to cut down chances of contracting the disease. BCG vaccination: The TB & Chest Service provides Bacille Calmette-Guerin (BCG) vaccination to all infants to guard them against tuberculosis. Children residing in Hong Kong below 15 years of age and have never received BCG before are also advised to receive the vaccine. Other precautions Regular exercise Adequate rest and sleep Balanced diet Avoiding alcohol and tobacco Breathing fresh air Absolutely curable, yet a killer disease in India Reason: Delayed diagnosis, lack of public awareness, irregular treatment and inaccurate dosage MK SINGH T uberculosis is an absolutely a curable disease. Right medicine at right time and the right course of treatment are key to treat tuberculosis successfully. Patient needs to follow the instructions of the physician in letter and spirit. Just persecution of medicine is not enough. TB being highly contagious disease, it is the public health responsibility of the doctor treating a patient has to make sure that his patient eventually gets relief. For this, he should ensure that the patient follows his instructions properly, lest however efficient the treatment might be it will not show the desired results. In fact, it is the responsibility of both the doctor and the patient to ensure that the treatment reaches to its logical conclusion. All the doctors treating TB are under obligation to choose correct line of treatment and prescribe right medicine. In case of any lapses, apart from the patient, the society at large will have to pay a heavy price. It is a pity almost 2.5 lakh people have lost their lives due to TB in India despite all the caution. On an average two people die in every three minute. Patients do not get the medicine in correct dosage as it should be and if they do they do not take it properly owing to negligence. In most cases patients do not follow the prescribed course and give up medicine mid-way. It doesn’t mean they don’t have the desire to live, but they do so due to lack of awareness. The need of the hour is to educate people. The Government is making medicine available to all, diagnosis too is not a big deal what is required is that the patient should avail the benefits. Only 50 per cent of the TB patients avail the benefits. Tuberculosis is a sensitive disease, we need to handle it sensitively but unfortunately we do not as most of the patients tend to break the duration of medication. They, however, start taking the medicine again after a gap. But this break journey renders tuberculosis drug resistant. For instance, multi-drug resistant (MDR) is extensively drug resistant (XDR) and in some cases total drug resistant (TDR). In these cases no drugs available will work. The current drug duration course is for six months. Although researches are on way to minimise the course as it might be the long duration by which people get fed up and leave the medicine. In India, to the earliest diagnosis of MDR is almost two to three months. During this period, many people lose their lives as they live without medicine. Now, under the new technique named “gene expert”, the diagnosis for MDR will take only a couple of hours. Before gene expert there was a technique called “lipa method” which takes two days in diagnosis MDR. With the help of these two techniques our Government has initiated a pilot testing project in more than 90 districts. The objective is to replace the earlier test method so that it can save the valuable time spent on diagnosis to bring down the causality. The first TB control programme was started in 1962 by the Government of India called National TB control program (NTCP). To analyze the benefit in 1992 our government with the help of WHO had evaluated the programme. In evaluation the expected result were not found due to some shortcomings in implementation. To overcome all the drawbacks the government again moved up with the Revised National TB control programme (RNTCP). In NTCP the period of treatment was one year but in RNTCP it is minimized by six months. DOTS were introduced in RNTCP. The government has put all his effort to restrain the causality. This RNTCP has brings down the causality to almost 2.5 lakhs against 5 lakhs. There still remain many challenges to tackle and to do so the government is trying to bring private hospitals, NGOs, health activists under one platform. Moreover, the government has made it a notifiable disease. In this case we can avail the actual data of people suffering from TB and through this we can gives the best treatment. Our effort is to diagnose it early to provide the best medicine in right dose so that the MDR and XDR will not evolve. The government has decided to eliminate TB by 2050. (With inputs from Prof Rajendra Prasad, director, Vallabhbhai Patel Chest Institute.) Medical Business DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Global sales boost Sun profit DTMT NETWORK Sun Pharmaceutical Industries reported a 74 per cent increase in consolidated net profit to Rs 1,531.09 crore in the quarter ended December 31 on robust sales in the global markets. “Profit a year earlier was Rs 881.3 crore”, Sun Pharma said in a statement. Net sales of the pharma major climbed 50 per cent to Rs 4,286.59 crore from Rs 2,852.01 crore in the year-ago period. Branded generic sales in India rose 20 per cent to Rs 947 crore, while finished dosage sales in the US grew 57 per cent to $434 million, it said. According to market analysts, the top two pharma majors, Sun Pharma and Lupin, have beaten street expectations by a long margin on all counts. Lupin had posted a 42 per cent increase in consolidated net profit to Rs 476.1 crore in Q3. International formulation sales outside the US were up 16 per cent at $84 million. International revenue accounted for more than 75 per cent of the total in the quarter. “Our overall performance reflects the focus on execution of our strategy. We are developing a differentiated and specialty business and continue to evaluate opportunities to enhance our global presence,” Sun Pharma Managing Director Dilip Shanghvi said. Sun Pharma said it is ranked second with a 5.3 per cent share in India’s Rs 74,000 crore pharmaceutical market, citing a December report by market research organisation AIOCD-AWACS. Shares of the company gained 0.6 per cent to Rs 614.70 at the close on the BSE. External sales of its active pharmaceutical ingredients (API) business posted a 17 per cent decline to Rs 174 crore, mainly due to increased captive consumption, the company said. Consolidated R&D expenses were at Rs 306 crore, or 7.1 per cent of sales. During the period, the company filed abbreviated new drug applications (ANDA) for five products. “After counting these, and adjusting for filings that were dropped, cumulatively ANDAs for 468 products have been filed with the USFDA (as on December 31),” the company said. ANDAs for four products received approvals in the third quarter, taking the total number of approvals to 337. Applications for 131 products await USFDA approval, including 14 tentative approvals, it said. The company revised its consolidated revenue growth forecast to 29 per cent compared with the previous estimate of 25 per cent. “The revised guidance takes into account the performance achieved in first nine months of the fiscal, higher base of Q4FY13 on consolidation of acquisitions as well as the risks associated with increase in competition for some products,” it said. Big layoff in Novartis: Cipla shares tank as Q3 earnings lag estimates 4,000 workers face DTMT NETWORK job loss or transfer DTMT NETWORK MUMBAI Swiss drug maker Novartis plans to cut or transfer up to 4,000 jobs and move a significant part of it to its India facility in Hyderabad, a news report said, quoting the German newspaper NZZ am Sonntag. The move, affecting up to 6 per cent of its workforce, is part of a cost-cutting strategy through which the company will be reducing the number of manufacturing sites, the agency cited the newspaper as saying. Novartis could not be reached for comment. The development comes at a time when multinational drug makers are facing increasing pressure to cut costs as patents expire. The measures “reflect the need to respond to a dynamically changing healthcare environment”, it said, adding that Novartis expects group headcount to remain largely flat in 2014. “We expect that an equal number of jobs will be cre- ated as are reduced,” the statement said. A significant number of jobs are expected to be moved to India, with the company saying that it plans to move existing operations in Hyderabad to a business services centre as part of its consolidation strategy. “The new centre is expected to open in late 2015 or early 2016 and will bring together Novartis operations that are currently spread across three sites in Hyderabad as well as provide for future growth,” the statement said. Novartis, which will face copycat competition for blood pressure, Pill Diovan once Ranbaxy Laboratories overcomes regulatory delays for its generic version, posted lower than expected core earnings per share last week. The company is also conducting a review of its overthe-counter, animal health and vaccines businesses, which lack the global scale of its pharmaceuticals operations. Shares of drug major Cipla slumped by over 6 per cent after the company posted a lower than estimated consolidated net profit of Rs 284.31 crore for the third quarter ended December 31, 2013. After making a weak opening, the scrip further lost 6.11 per cent to Rs 387.55 on the BSE. At the NSE, Cipla’s scrip tanked 6.17 per cent to Rs 387.25. The stock was the top loser among the bluechips on both Sensex and Nifty during the morning trade. The company announced results after market hours on February 12. “Cipla posted numbers that were above expectations on sales front, while net profit came below expectations,” Angel Broking said in a report. The company had posted a net profit of Rs 340.31 crore during the same period of the previous fiscal. Consolidated net sales of the company stood at Rs 2,552.63 crore for the third quarter. It had stood at Rs 2,070.53 crore in the same period of previous fiscal, Cipla Ltd said on February 12. “Current year figures include the relevant results of Cipla’s subsidiaries from the date they became subsidiary of the company and therefore the corresponding figures for the previous period are not comparable,” it added. During the period under review, the comp a n y ’s domestic revenues stood at Rs 1,044 crore as against Rs 927 crore d u r ing the s a m e period of previous fiscal. USFDA ban lands Ranbaxy in the red DTMT NETWORK US drug regulator USFDA recently blacklisted Ranbaxy Laboratories’ Toansa plant in Punjab — the generic drug makers’ fourth factory to face such an import ban — dealing a body blow to the company’s reputation and bringing its share prices crashing by nearly 20 per cent. Japanese drug maker Daiichi Sankyo had bought the company for an eye-popping $4.6 billion (about Rs 20,000 crore at the time) in 2008 from its former promoters, Malvinder Mohan Singh and family. The latest ban could not have come at worse time for the one-time poster-boy of India’s pharmaceutical industry that is nursing a welter of festering wounds from runins with regulators to employee exits and penalties for felony. The company will now have to negotiate prolonged scrutiny before it can introduce new products in key markets. Analysts warned of a drop in earnings by up to 40 per cent over the next one year as exports from Indian are effectively ruled out. Disclaimer: We exercise due care, diligence and caution in publishing the news and articles. None of the report or articles constitute any form of advice, recommendation or arrangement by us. Readers are requested to make their own research and enquiries prior to making any investment or other decisions. We are not liable for any claim of loss or damages suffered by any person due to such decisions solely based on our reports or articles. It could also hit the company’s plans to exploit “patent cliff” opportunities, ruling out a shot at a multibillion dollar opening of drugs whose patents expire soon. Ranbaxy has been found wanting compared to its peers, facing pointed posers on production and hygiene standards. The USFDA prohibited it from making and selling active pharmaceutical ingredients (API) from its facility in Toansa. Violations included staff re-testing raw materials and drugs after they “failed analytical testing and specifications in order to produce acceptable findings.” 15 HCL forays into healthcare business; to invest Rs 1k crore DTMT NETWORK NEW DELHI With the launch of HCL Healthcare, the technology giant forays into wellness and preventive healthcare market. The company is looking forward to invest Rs 1,000 crore in next five years to create India’s largest network of outdoor patient clinics. Promoted by billionaire Shiv Nadar the company is already running two clinics in the Delhi NCR region. Think smartphone apps, video con- sultation and online monitoring of real-time health status of patients that will help them get rid of unwieldy paperwork. “The idea is to capture diseases early and nip problems in the bud,” says CEO of HCL Avitas Harish Natarajan. Medical Mix 16 DRUG TODAY MEDICAL TIMES 1st - 31st March 2014, New Delhi Smart glasses to help doctors ‘see’ cancer cells MUKUL VYAS A big leap forward in the treatment of cancer with accurate precision! Now special glasses developed at Washington University School of Medicine in St Louis may help surgeons visualise cancer cells, which glow blue when viewed through the glasses. Cancer cells are notoriously difficult to see, even under high-powered magnification. These smart glasses are designed to make it easier for surgeons to distinguish cancer cells from healthy ones and ensure that no stray tumour cell is left behind during surgery. The wearable technology was used during surgery for the first time at Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine. Julie Margenthaler, MD, breast surgeon and associate professor of surgery at the Washington University, who performed the operation, said: “We’re in the early stages of this technology, and more development and testing will be done, but we’re certainly encouraged by the potential benefits to patients.” “Imagine what it would mean if these glasses eliminated the need for follow-up surgery and the associated pain, inconvenience and anxiety,” he added. Current standard of care requires surgeons to remove the tumour and some neighboring tissue that may or may not include cancer cells. The samples are sent to a pathology lab and viewed under a microscope. If cancer cells are found in neighboring tissue, a second surgery is often recommended to remove additional tissue that also is checked for the presence of cancer. The glasses could re- duce the need for additional surgical procedures and subsequent stress on patients, as well as time and expense. Margenthaler said about 20 to 25 per cent of breast cancer pa- tients who have lumps removed require a second surgery because current technology doesn’t adequately show the extent of the disease during the first operation. RNI No. DELBIL/2012/45560 Published by Poonam Mishra for and on behalf of Drug Today Medical Times, 252, Kailash House, Kotla, Mayur Vihar –I, Delhi -110 091 Ph No.: (011) 22792078, 22792554, Fax No.: (011) 22759677 and printed at India Offset Printers, X-36, Okhla Industrial Area, Phase-II, Delhi - 110 020 Email - [email protected] Editor: Lalit Mishra © All rights reserved. Reproduction in whole or in part without written permission of the publisher is strictly prohibitedWe have taken every possible care to avoid errors. Since this publication is being sold on the condition and understanding that information given herein is merely for reference, it must not be treated as an authority of or binding in any way on the writers, editors, publisher, and printer and sellers who do not owe any responsibility for any damage or loss to any person. All disputes are subject to the exclusive jurisdiction of competent court and forums in Delhi/NCR only. For the use only of a registered Medical Practitioner or a hospital or a Laboratory For inquiries call us at : Jokes n An Old man went to the doctor complaining a terrible pain in his leg. “I am afraid it’s just old age”, replied the doctor, “there is nothing we can do about it.” “That can’t be” replied the old man, adding “you don’t know what you are doing.” “How can you possibly know I am wrong?” questioned the doctor. “Well it’s quite obvious. My other leg is fine, and it’s exactly of same age!” reasoned the old man. n Lady to Doctor: My husband has the habit of talking in sleep. What should I give him to cure? Doctor: Give him an Opportunity to speak when he is awake. n Dad: What’s your result? Son: I’ve failed in five subjects. Dad: Now onwards don’t call me dad! Son: Oh! Come on dad, it’s my school test, not a DNA test. n I was very scared about going to the eye specialist to get a certain procedure done on my Sudoku solution eyes. The doctor tried to put me at ease but to no avail. It was after he finished with my first eye that I nearly jumped out of the chair. “There there”, he said “only one eye left!” Crossword solution 09971523292