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Key Points
LIPO-6 is a powerful and extremely popular fat-burner that utilizes
maximum strength liquid capsules for superior absorption and rapid
results. This highly advanced method of delivering fast-acting
fat-burning compounds makes LIPO-6 a great choice when it comes
to weight-loss products.
When LIPO-6 was released in 2005 it was the world’s first liquid
capsule fat burner. Over the years LIPO-6 has established itself as a
proven and reliable tool to lose weight fast. It works great for everyone,
man or woman, fitness enthusiast or bodybuilder. LIPO-6 consists
of only pure pharmaceutical-strength ingredients that allow for a
pronounced, yet consistent and predictable fat-loss effect.
Furthermore LIPO-6 is the only liquid capsule fat burner that utilizes
all natural vegetable capsules which are completely devoid of any
animal products. It is no wonder that LIPO-6 was voted ‘Fat-Loss
Product of the Year’ in 2005, 2006, 2007 and 2008 by the popular
consumer & industry website www.bodybuilding.com. To this day
LIPO-6 is the benchmark for all other liquid capsule fat burners.
Some key product highlights include:
Synephrine HCL
SUPPLEMENT FACTS
Serving Size: 2 Liqui-caps
• Boosts norepinephrine levels
Amount per serving
% Daily Value*
Synephrine HCL
20mg
*
• Increases thermogenesis,
Synthetic 99% Guggulsterones Z&E 1:1
20mg
*
enhancing the breakdown of
Yohimbine HCL
3mg
*
Caffeine Anhydrous USP
200mg
*
fat with muscle-sparing effect Bioperine **
5mg
*
• Revs your metabolism without * Daily Value not established.
Other Ingredients: Vegetable Cellulose , Purified Water
altering heart rate or blood
**Bioperine is a registered trademark of Sabinsa Corp.
pressure
• Exerts a strong appetite suppressing effect
®
†
®
Synthetic 99% Guggulsterones Z&E 1:1
• Increases thyroid hormone activity, significantly augmenting metabolism
• Decreases body fat levels
This Product Utilizes
• Lowers LDL cholesterol
• Inhibits excessive inflammation from intense exercise
Yohimbine
• Increases lipolytic activity (breakdown of stored body fat)
• Improves cognitive alertness and overall mental function
Caffeine Anhydrous USP
Free of Animal Products
• Boosts metabolism, helps shed body fat
• Catalyzes neuromuscular transmission, enhancing strength gains and
increasing work volume
• Improves mental alertness and enhances mood
Bioperine®
• Enhances the absorption of key ingredients in LIPO-6 making them
more potent
• Induces thyroid hormone stimulation, increasing metabolism
• Augments antioxidant activity in your body and from foods
Available in 120 ct and 240 ct.
LIPO-6
Detailed Facts
Synephrine HCL
Synephrine activates ß-3 adrenoreceptors and, therefore, displays a lipolytic and thermogenetic capacity as it
boosts norepinephrine levels (1). By consuming synephrine prior to workouts, you enhance fat breakdown with
its subsequent utilization for energy. Furthermore, synephrine has a significant muscle-sparing effect while
expending energy at the expense of body fat. (2) Synephrine has demonstrated its efficacy as an ephedra
alternative for revving your metabolism without altering heart rate or blood pressure. (3-6) Synephrine also exerts
a strong appetite suppressing effect making it the ideal compound for calorie-restricted diets.
Synthetic 99% Guggulsterones Z&E 1:1
E- and Z-Guggulsterones are the bioactive compounds of Guggul (Commiphora Mukul) that have purported
benefits for lowering LDL cholesterol and triglycerides. (7, 8) Guggulsterones also have the capacity to rev your
metabolism by increasing the overall thyroid hormone activity with significant influence on triiodothyronine
(T3) hormone (thyroid regulator). (9-11) By supplementing with guggulsterones you are also inhibiting excessive
inflammatory responses you experience from your exercise regimen. (12) LIPO-6 utilizes a 99% pure 1:1 ratio of
synthetic Guggulsterones Z&E.
Yohimbine HCL
Yohimbine is just right for the thermogenetic concoction in LIPO-6 to help induce lipolysis (fat burning)
without the side effects from other fat burners (i.e. increased heart rate, increased blood pressure, anxiety)(14, 15)
In particular, Yohimbine induces fat breakdown where fat stores prevail as problem areas. Furthermore,
yohimbine induces excitatory effects, improving elements of cognitive function, primarily alertness. (15)
Caffeine Anhydrous USP
Caffeine provides a variety of enhancements for the neuromuscular system; including increases in secretion of
catecholamines (16-18) and calcium release from the sarcoplasmic reticulum (19). Caffeine, with its capacity to
optimize skeletal muscle contraction from augmented neuromuscular transmission (20), has demonstrated its
ability to enhance strength gains and increase work volume (21-23). While allowing you to work harder caffeine
also boosts your metabolism, assisting in body fat loss while recruiting lean body mass. (24, 25) Caffeine also
improves mental alertness and mood function, optimizing your level of focus through your workouts or
fatigue-battling tasks. (26, 27) By providing caffeine in its anhydrous form, you’re getting a more pure, synthetic
form for maximal potency.
Bioperine®
Bioperine is patented and powerful component of Piper Nigrum L (black pepper) that will stimulate your
antioxidant capacity and induce thermogenesis. Bioperine enhances drug and nutrient absorption in the body
which improves the effectiveness of the key ingredients in LIPO-6. Bioperine further helps to protect your
body’s cells from the damages of oxidative stress. (28-30) In addition, Bioperine possesses thyroid-stimulating
capability to significantly diminish body fat and help modulate insulin levels. (31)
All numbered references marked above can be found in the References section to follow.
LIPO-6
Product Label
FAST-ACTING LIQUID CAPSULE FAT BURNER FOR MAXIMUM RESULTS
LIPO-6 LIPO-6 LIPO-6 LIPO-6 LIPO-6 LIPO-6 LIPO-6 LIPO-6
SUPPLEMENT FACTS
Serving Size: 2 Liqui-caps
Amount per serving
BURN FAT FAST
Servings Per Container: 60
% Daily Value*
Synephrine HCL
20mg
Synthetic 99% Guggulsterones Z&E 1:1 20mg
Yohimbine HCL
3mg
Caffeine Anhydrous USP
200mg
Bioperine®**
5 mg
* Daily Value not established.
With Liquid Capsule Technology
*
*
*
*
*
LIPO-6 is a ground breaking fat-loss formula that utilizes a modern
liquid-capsule delivery system for maximum results. This unique
product is the first and only weight loss agent that combines speed
and strength with the usage of animal-free capsule material assuring
rapid and healthy weight-loss. It is no wonder Lipo-6 was voted
Fat-Loss Product of the Year three times in a row.
Other Ingredients: Vegetable Cellulose†, Purified Water
**Bioperine® is a registered trademark of Sabinsa Corp.
†
This product utilizes only natural vegetable capsules that are free of animal
products.
Strength: Lipo-6 consists of pure pharmaceutical-strength ingredients
and does not contain inferior herbal compounds that cannot be
efficiently absorbed by the human body. This allows for a pronounced,
yet consistent and predictable, fat-loss effect with Lipo-6 as opposed
to a guessing game in so called other fat burners that
rely on herbal ingredients.
MAXIMUM
STRENGTH
Accelerated Fat-Loss Formula
Developed by and exclusively manufactured for:
Nutrex Research, Inc.
Oviedo, FL 32765
Lipo6.com • 1-888-3NUTREX
6
Dietary Supplement - 120 Liqui-Caps
Animal-Free Capsule Material: Lipo-6 utilizes only
natural vegetable capsules that are free of animal products.
Offering capsules that are of plant origin makes Lipo-6
the ideal choice for the health conscious person.
53237 00080
The statements on this label have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure or
prevent any disease.
Speed: Superior liquid capsules which have been developed by one of
the world’s leading pharmaceutical companies offer a rapid and complete
absorption of the powerful fat-burning components in Lipo-6. Without
delay, Lipo-6 goes to work almost instantly by targeting stored body
fat, controlling your appetite and speeding up your metabolism.
8
RECOMMENDED USE FOR FAT LOSS: Take 2 liqui-caps 30 minutes before
breakfast and 2 more liqui-caps in the afternoon. Start off with only 2 liqui-caps
on your first two days (1 in the morning and 1 in the afternoon) and increase
dosage by 1 liqui-cap every two days until maximum dosage of 4 liqui-caps
per day is reached. DO NOT EXCEED 4 LIQUI-CAPS PER DAY. Do not take
within 6 hours of sleep.
WARNING: Not for use by persons under age 18. Do not use if pregnant or
nursing. Do not exceed recommended dose. Do not consume synephrine or
caffeine from other sources, including but not limited to, coffee, tea, soda and
other dietary supplements or medications containing phenylephrine or caffeine.
Contains caffeine. Do not use for more than 8 weeks. Consult your physician
prior to use if you are taking medication, including but not limited to, MAOI
inhibitors, antidepressants, aspirin, non-steroidal anti-inflammatory drugs or
products containing phenylephrine, ephedrine, pseudoephedrine, or other
stimulants. Consult your physician prior to use if you have a medical condition,
including but not limited to, heart, liver, kidney, or thyroid disease, psychiatric
disorders, difficulty urinating, diabetes, high blood pressure, cardiac arrhythmia,
recurrent headaches, enlarged prostate or glaucoma. Discontinue 2 weeks
prior to surgery or if you experience rapid heart beat, dizziness, severe headaches
or shortness of breath. KEEP OUT OF REACH OF CHILDREN.
LIPO-6
References
1. D’Andrea G, Terrazzino S, Fortin D, Farruggio A, Rinaldi L, Leon A. HLPC electrochemical detection of trace amines
in human plasma and platelets and expression of mRNA transcripts of trace amine receptors in circulating leukocytes.
Neurosci Lett. 2003, 346:89-92.
2. Kalman DS, Colker CM, Shi Q, Swain MA. Effects of a weight-loss aid in healthy overweight adults: double-blind,
placebo-controlled clinical trials. Curr Ther Res. 2000; 61(4):199-205.
3. Colker CM, Kalman DS, Torina GC, Perlis T, Street C. Effects of Citrus aurantium Extract, Caffeine, and St. John’s
Wort on body fat loss, lipid levels, and mood states in overweight healthy adults. Curr Ther Res. 1999; 60(3):145-153.
4. Pensak SR, Jann MW, Cold JA, Hon YY, Desai HD, Gurley BJ. Seville (sour) orange juice: synephrine content and
cardiovascular effect in normotensive adults. J Clin Pharmacol. 2001, 41(10):1059-63.
5. Moro CO, Basile G. Obesity and medicinal plants. Fitoterapia. 2000, 71 Suppl 1:S73-82.
6. Kreider RB, Almada AL, Antonio J, Broeder C, Earnest C, Greenwood M, Incledon T, Kalman DS, Kleiner SM,
Leutholtz B, Lowery LM, Mendel R, Stout JR, Willoughby DS, Ziegenfuss TN. ISSN exercise & sport nutrition review:
research and recommendations. Sport Nutr Rev J. 2004, 1(1):1-44.
7. Nityanand S, Srivastava JS, Asthana OP. Clinical trials with guglipid. A new hypolipidaemic agent. J Assoc Physicians
India. 1989; 37(5):323-8.
8. Urizar NL and Moore DD. GUGLIPID: a natural cholesterol-lowering agent. Annu Rev Nutr. 2003; 23:303-13.
9. Panda S and Kar A. Guggulu (Commiphora mukul) induces triiodothyronine production: possible involvement of lipid
peroxidation. Life Sci. 1999; 65(12):PL137-41.
10. Panda S and Kar A. Guggulu (Commiphora mukul) potentially ameliorates hypothyroidism in female mice. Phytother
Res. 2005; 19(1):78-80.
11. Kreider RB, Almada AL, Antonio J, Broeder C, Earnest C, Greenwood M, Incledon T, Kalman DS, Kleiner SM,
Leutholtz B, Lowery LM, Mendel R, Stout JR, Willoughby DS, Ziegenfuss TN. ISSN exercise & sport nutrition review:
research and recommendations. Sport Nutr Rev J. 2004, 1(1):1-44.
12. Deng R. Therapeutic effects of guggul and its constituent gugglesterone: cardiovascular benefits. Cardiovasc Drug Rev.
2007; 25(4):375-90.
13. Ostojic SM. Yohimbine: the effects on body composition and exercise performance in soccer players. Res Sports Med.
2006; 14(4):289-99.
14. McCarty MF. Pre-exercise administration of yohimbine may enhance the efficacy of exercise training as a fat loss
strategy by boosting lipolysis. Med Hypotheses. 2002; 58(6):491-5.
15. Morgan CA 3rd, Southwick SM, Grillon C, Davis M, Krystal JH, Charney DS. Yohimbine-facilitated acoustic startle
reflex in humans. Psychopharmacology (Berl). 1993; 110(3):342-6.
16. Costill, D. L., Dalsky, G. P., Fink, W. J. Effects of caffeine ingestion on metabolism and exercise performance.
Med. Sci. Sports Exerc. 1978, 10:155-158.
17. Graham, T. E. Caffeine and exercise: Metabolism, endurance, and performance. Sports Med. 2001, 31:786-807.
18. Ivy, J. L., Costill, D. L., Fink, W. J., Lower, R. W. Influence of caffeine and carbohydrate feedings on endurance
performance. Med Sci. Sports Exerc. 1979, 11:6-11.
19. Lopes, J. M., Aubier, M., Jardim, J., Aranda, J. V., and Macklem, P. T. Effect of caffeine on skeletal muscle function
before and after fatigue. J Appl. Physiol. 1983, 54:1303-1305.
20. Williams, J. H. Caffeine, neuromuscular function and high-intensity exercise performance. J Sports Med. Phys. Fitness
31:481-489. 1991.
21. Kalmar, J. M., and Cafarelli, E. Effects of caffeine on neuromuscular function. J Appl. Physiol. 1999, 87:801-808.
22. Beck, T. W., Housh, T. J., Schmidt, R. J., Johnson, G. O., Housh, D. J., Coburn, J. W., and Malek, M. H. The acute
effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities. J Strength
Cond Res. 2006, 20(3):506-510.
23. Astorino, T. A., Rohmann, R. L., Firth, K. Effect of caffeine ingestion on one-repitition maximum muscular strength.
Euro J of Appl Physiol. 2008. 102(2):127-132.
24. Acheson, K. J., Zahorska-Markiewicz, B., Pittet, P., Anantharaman, K., and Jequier, E. Caffeine and coffee: their
influence on metabolic rate and substrate utilization in normal weight and obese individuals. American Journal of
Clinical Nutrition. 1980. Vol 33, 989-997.
25. Dulloo, A. G., Geissler, C. A., Horton, T., Collins, A., Miller, D. S. Normal caffeine consumption: influence on
thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr. 1989. 49:44-50.
26. Lieberman HR, Tharion WJ, Shukitt-Hale B, Speckman KL, Tulley R. Effects of caffeine, sleep loss and stress on
cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land. Psychopharmacology (Berl). 2002,
164(3):250-61.
LIPO-6
References
27. Haskell CF, Kennedy DO, Wesnes KA, Scholey AB. Cognitive and mood improvements of caffeine in habitual
consumers and habitual non-consumers of caffeine. Psychopharmacology (Berl). 2005, 179(4):813-25.
28. Vijayakumar RS, Surya D, Nalini N. Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with
high fat diet induced oxidated stress. Redox Rep. 2004; 9(2):105-10.
29. Srinivasan K. Black pepper and its pungent principle-piperine: a review of diverse physiological effects. Crit Rev Food
Sci Nutr. 2007; 47(8):735-48.
30. Badmaev V, Majeed M, Norkus EP. Piperine derived from black pepper increases the plasma levels of coenzyme Q10
following oral supplementation. J Nutr Biochem. 2000; 11:109-113.
31. Vijayakumar RS and Nalini N. Piperine, an active principle from Piper nigrum, modulates hormonal and apo
lipoprotein profiles in hyperlipedeic rats. J Basic Clin Physiol Pharmacol. 2006; 17(2):71-86.