Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Derm Digest VETERINARIAN EDITION Indianapolis IN • Louisville KY • Marietta GA Marina del Rey CA • Pasadena CA • San Diego CA • Tustin CA Welcome to the Derm Digest for Veterinarians Thank you for taking a moment to review our premiere issue of Derm Digest- Veterinarian Edition. The standard edition of Derm Digest is written for clients and pet owners interested in animal dermatology while the goal of the Veterinarian Edition is to provide veterinary professionals with the latest information in animal dermatology, along with useful tips and information as provided by the doctors and staff of Animal Dermatology Clinic. New Animal Dermatology Website In July our revamped website was launched. There are new updates and features for veterinarians including a calendar of dates where you can find our doctors are lecturing, dosing information for common drugs used at Animal Dermatology Clinic and disease information handouts. The site is under constant development and we are continuing to add information on a regular and ongoing basis. Go to www.animaldermatolgy.com and take a tour of the site. You can also sign up to have Derm Digest-Veterinarian Edition emailed directly to you. While you’re at it join our Facebook of the Animal Dermatology Clinic in your area (or all of them) as well as following us on Twitter. If you have suggestions of what you would like to see in upcoming issues of this newsletter, please email [email protected] with “Dr suggestion” in the subject line. We will give each suggestion serious consideration and try our best to exceed your expectations. In the meantime, please enjoy our first newsletter. Dr. Andrew Rosenberg joins Animal Dermatology Clinic Animal Dermatology Clinic is pleased to announce that Dr. Andrew Rosenberg has joined the staff of Animal Dermatology Clinic. Dr. Rosenberg was practicing at Long Island Veterinary Specialists in Plainview, NY and will now begin his residency program to attain Diplomate status from the American College of Veterinary Dermatology. He received his doctorate from Cornell University where he developed an interest in dermatology. "I am very excited to be joining the Animal Dermatology Clinic team and look forward to working in such a beautiful part of the country. I have a strong interest in both allergies and autoimmune skin diseases and my goal is to help pets suffering from all dermatologic ailments." Dr. Rosenberg is a native of Long Island and has relocated to Orange County, CA with his dog Mason. He says that he enjoys skiing, watching sports and travelling in his spare time and will be watching New York Jets football games this fall. Dr. Rosenberg will be seeing patients in the Tustin CA clinic. www.animaldermatology.com Page 2 Derm Digest-Vet Edition In April 2009, the annual meeting of the North American Veterinary Dermatology Forum met in Savannah, GA. The conference attracted leading and active veterinary dermatologists across the United States for a week of lectures and continuing education. The following are abstracts from the conference. Evaluation of otoscope cone disinfection techniques and contamination level in small animal private practice AL Kirby , WS Rosenkrantz‡, RM Ghubash , B Neradilek†, NL Polissar† Animal Dermatology Clinic, Marina Del Rey, California, USA ‡ Animal Dermatology Clinic, Tustin, California, USA † The Mountain-Whisper-Light Statistical Consulting, Seattle, Washington, USA Abstract: The objective of this study was to evaluate the level of contamination of otoscope cones in private practice, and to determine the most effective method of disinfection. Fifty-one small animal practices participated in the study, which included a detailed survey regarding otoscope cleaning, storage and usage. The hospitals were also informed that a quantitative culture of the cleaned stored otoscope cones would be performed. One hospital went out of business prior to culture; so only 50 hospitals completed the study. Using sterile technique, 2 cones from each of the 50 hospitals were swabbed and submitted for quantitative culture. 29% of the samples were contaminated and the organisms consisted of: Flavobacterium brevis (10%), Pseudomonas aeruginosa (6%), Pseudomonas alcaligenes (4%), Staphylococcus intermedius (4%), Corynebacterium spp. (2%), Bacillus spp. (1%), Enterococcus faecalis (1%) Malassezia spp. (1%). There was no statistically significant difference between storage type (dry vs. stored in solution) and for the instrumentation used to clean the cones (brush, cotton-tipped applicator, both vs. none). There was a statistically significant difference between the different cleaning solutions (p<. 001) and between the storage solutions (p=0.003). A single most effective cleaning solution was unable to be determined due to the large number of solutions utilized. Cetylcide G→ (Cetylite Industries, Inc., Pennsauken, NJ) was the most effective of the three most commonly used storage solutions when used as directed (P<0.001). The level of contamination had a positive association with the frequency of cone use and a negative association with the frequency of storage solution replacement. Source of Funding This study is self-funded Conflicts of Interest No conflicts of interest have been declared. Nisin impregnated wipes for the treatment of canine pyoderma and surface bacterial Colonization L. A. Frank1, E. M. Kirzeder1, J. A. Davis1, J. J. Rejman2 1Department of Small Animal Clinical Sciences, University of Tennessee, College of Veterinary Medicine, Knoxville, Tennessee, USA 2ImmuCell Corporation, 56 Evergreen Drive, Portland, ME 04103 Abstract: Nisin is an antimicrobial peptide produced by Lactococcus lactis. Nisin is marketed in a wipe format to help prevent bovine mastitis. Recently methicillin-resistant Staphylococcus spp isolated from companion animals were susceptible to nisin in vitro. The purpose of this research was Derm Digest – Vet Edition Page 3 to evaluate nisin wipes for treating surface infections and pyodermas in dogs. Study A enrolled 10 dogs with focal surface bacterial colonization. Cultures and cytology were obtained on Day 0. Dogs were treated twice daily with nisin wipes and re-evaluated weekly. Study B enrolled 18 dogs with superficial pyoderma. Cultures and cytology were obtained on Day 0. Two areas with similar lesions were selected and randomly assigned to receive either treatment or nothing. Nisin wipes were applied to the treatment areas twice daily. After one week dogs were started on clindamycin or another antibiotic based on culture and susceptibility and rechecked weekly. Visual assessment and cytology were performed at each recheck for both studies. In Study A, Pseudomonas was cultured from five dogs and Staphylococcus intermedius from two dogs. The lesions of four dogs resolved with treatment while those with Pseudomonas and Malassezia did not. In Study B, cultures from all but one dog yielded Staphylococcus intermedius susceptible to clindamycin. In 10 dogs treated areas showed improvement after one week and cleared more rapidly than the untreated areas. Mean time until cytological resolution was 1.4 versus 2.1 weeks. The mean time until clinical resolution was 2.5 versus 2.8 weeks. Nisin wipes demonstrated efficacy in treating some dogs with bacterial skin infection. This study was funded by ImmuCell Corporation. Efficacy of metaflumizone plus amitraz for treatment of juvenile and adult onset generalized demodicosis in dogs: pilot study of 24 dogs W.S. Rosenkrantz Animal Dermatology Clinic, Tustin, CA Abstract: A spot-on formulation containing metaflumizone plus amitraz (ProMeris®/ProMeris Duo® for dogs, Fort Dodge Animal Health, Overland Park, KS) was evaluated in 24 dogs with juvenile (n = 13) or adult onset (n=11) generalized demodicosis. Case selection included option for initial therapy by owner preference (3/24), undesirable side effects of previous treatment (6/24) or lack of efficacy of previous treatments (15/24). All were treated with a minimum dose rate (20mg kg-1of metaflumizone and amitraz, 0.133ml/kg-1) at a 14 day interval until 2 consecutive negative skin scrapings were obtained. Cases were evaluated every 30 days. The treatment times ranged from 90 – 180 days. The results were based on reduction of mite numbers. A grading score was assigned as excellent if no mites were identified for 60 days (2 negative scrapings), good if 75% reduction, fair if 50% reduction and poor if no change in mites numbers within 90 days. Other antimicrobial therapies were allowed throughout the study. Cases were monitored for side effects and complications. Of the 13 juvenile onset cases, 12/13 (92.3%) had excellent results and 1/13 (7.7%) had poor results. In the 11 adult onset cases, 5/11 (45.4%) had excellent results, 3/11 (27.3%) had good results and 3/11 (27.3%) had poor results. Side effects included a pemphigus foliaceus-like pustular eruption (1), vomiting (1), diarrhea (2), transient lethargy (2) and product odor (7). Efficacy was comparable to other products, and metaflumizone plus amitraz is an approved alternative to other treatment options. Longer term remission and cure rates still need to be evaluated. The spot-on formulation metaflumizone plus amitraz (ProMeris®/ProMeris Duo® was supplied by Fort Dodge Animal Health, Overland Park, KS