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Integumentary System Structure  Skin is the largest organ of the body. In adults, the skin covers an area of approximately 2 square meters and accounts for nearly 20% of one's body weight. Its thickness varies from 0.3-4.0 mm depending on the location on the body. Functions   Skin is extremely important to normal physiologic function secondary to the roles that it plays in maintaining homeostasis. The chief functions of the skin are as follow:        Regulation of body temperature Protection Sensation/perception Excretion Immunity Blood reservoir Synthesis of vitamin D         INTEGUMENTARY SYSTEM (largest organ - 15-20% total body mass) FUNCTIONS : 1. Barrier (to physical, chemical and biological agents) 2. Homeostatic -prevents water loss and regulates body temperature 3. Sensory -touch, pain and pleasure sensitivity 4. Secretory -converts precursor molecules to vitamin D; lubricants for hair; pheromones 5. Excretory - sweat  Two Principal layers:  Epidermis Outer layer  Cells are highly differentiated   Dermis  Supportive tissue  Beneath these two layers is a 3rd layer of subcutaneous adipose tissue Epidermis Thin but tough  Avascular  Body’s first line of defense  Color derived from 3 sources  Stratified into several layers   Stratum germinativum or basal layer  Stratum corneum Skin Cells     Langerhans cells Melanocytes Keratinocytes Merkel Dermis      Irregular fibrous connective tissue Fibroblasts produce collagen and elastin Papillary layer Abundant capillaries Accessory skin structures     Hair follicles Nail follicles Sensory receptors glands Hair   Follicle made of epidermal tissue Growth similar to epidermis Nail Follicles    Nails are hard plates of keratin Nails produced like hair Nail bed is living dermis and epidermis Name the Structures Glands     Sebaceous Ceruminous Apocrine Eccrine Blood vessels   Capillaries Arterioles Sensory Touch  Pressure  Temperature  Pain  Subcutaneous Tissue    AKA: superficial fascia Second line of defense Consists of:   Areolar connective tissue Adipose tissue The Aging Process Slow atrophy of skin structures  Loss of elasticity  Layers become thin  Gland decrease in number and function  Vascularity decreases, becomes more fragile  Number and function of melanocytes decreases  Normal variations Liver spots (Lentigines)  Freckles  Mole (nevus)  Birthmark  Cherry (senile) angioma  Keratoses  Acrochordons (skin tags)  Vitiligo  Common Skin Lesions          Macule Papule Vesicle Pustule Patch Plaque Nodule Wheal Tumor          Bulla Crust Scale Fissure Erosion Ulcer Excoriation Nevus Cyst Skin assessment  Color           Erythema Cyanosis Jaundice Pallor Hair distribution Mobility and turgor Lesions Temperature and moisture Capillary refill History Diagnostic procedures Wood’s Light examination  Patch testing  Biopsy  Potassium hydroxide (KOH)  Tzank smear  Scabies scraping  Patch Testing Biopsy    Shave biopsy Punch biopsy Surgical excision Dressings Protect wounds  Retain moisture to promote healing  Several types   Wet  Dry  Absorbent  Occlusive Phototherapy Light in combination with drugs Treatment for: psoriasis, vitiligo, chronic eczema Contraindications: Hx of herpes simplex infection, skin cancer, cataracts, lupus erythematosus. Phototoxicity: redness, vesicles, pain Maintain Healthy Skin Vitamin A  Stop smoking  Sun Screen  pachy/onych/ia thick/nail/condition of kerato/myc/osis hard/fungus/condition or increase dermato/logist skin/one who specializes in treatment of histo/troph/ic tissue/nourishment or development/pertaining to hyper/onych/ia above or excessive/nail/condition of leuko/trich/ia white/hair/condition of kerat/osis hard/condition or increase pachy/dermat/osis thick/skin/condition or increase epi/dermis upon/skin lip/oma fat/tumor sub/cutane/ous below or under/skin/pertaining to an/hidr/osis without/sweat/condition or increase histo/dia/lysis tissue/across or through/breaking down or dissolution dys/plas/ia painful, difficult or faulty/formation/condition of xantho/derma yellow/skin dys/plas/tic painful, difficult or faulty/formation/pertaining to pachy/dermato/cele thick/skin/pouching or hernia erythro/dermat/itis red/skin/inflammation histo/tox/ic tissue/poison/pertaining to melano/cyt/e black/cell/noun marker xer/osis dry/condition or increase purpur/ic purple/pertaining to squam/ous scale/pertaining to sebo/rrhea sebum(oil)/discharge steato/lysis fat/breaking down or dissolution Study Guide  Know the skin diagram  Structure and function Normal skin markings  Tests and treatments: what are they for, patient teaching and preparation  Burns  Skin lesions  Disorders