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Cubist Pharmaceuticals, Inc. Infectious Disease CNS Cardiovascular Disease DELEGATE(S) Brad Prosek 65 Hayden Avenue Lexington, MA 02421 USA HIGHLIGHTS Recent www.cubist.com Cubist Pharmaceuticals and Hydra Biosciences announce plans to begin Phase 1 Clinical Trial for Novel TRPA1 Modulator to treat acute pain. Incorporated: 1992 Employees: 700 Ownership: Public Cubist announces Full Year 2011 total CUBICIN® net product revenues of USD $735.5 Million, up 18% over 2010. NASDAQ: CBST Cubist announces first patient dosed in pivotal global Phase 3 Trial of CXA-201 for Complicated Intra-Abdominal Infections. MISSION/BACKGROUND Cubist Pharmaceuticals, Inc. is a biopharmaceutical company focused on the research, development, and commercialization of pharmaceutical products that address significant unmet medical needs in the acute care environment. Cubist is headquartered in Lexington, Mass. Additional information can be found at Cubist’s web site at www.cubist.com. ALLIANCES Optimer, AstraZeneca, Novartis, Merck-Banyu, Hydra Biosciences, others... PRODUCTS Name Phase Indication CUBICIN On Market Bacterial Infection ENTEREG On Market Post Operative Ileus DIFICID On Market Clostridium Difficile Infections CXA-201 Phase III Gram Negative Infections CB 183, 315 Phase III Clostridium Difficile Infections Novel TRPA1 Modulator Phase I Acute Pain Company Profiles – 10