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Infectious Diseases Within the HKPR District REPORT JULY 2010 Executive Summary……………………………………………………... Introduction……………………………………………………………… Campylobacteriosis……………………………………………………… Chlamydia………………………………………………………………... Cryptosporidiosis………………………………………………………... Giardiasis………………………………………………………………… Hepatitis C……………………………………………………………….. Influenza…………………………………………………………………. Salmonellosis…………………………………………………………….. Streptococcal Pneumoniae Disease…………………………………….. Glossary………………………………………………………………….. 2-3 4 5-7 8-10 11-13 14-16 17-19 20-22 23-25 26-28 29-31 Any questions, suggestions, or requests for further information pertaining to this report may be directed to: Department of Epidemiology and Evaluation Services, Haliburton, Kawartha, Pine Ridge District Health Unit 200 Rose Glen Road Port Hope, Ontario L1A 3V6 Tel: (905) 885 9100 Email: mailto:[email protected] Website: http://www.hkpr.on.ca/ 1 Executive Summary Introduction Infectious diseases can easily be spread among people, resulting in mild to severe illness for infected individuals. Because of the contagious nature of these illnesses, health care providers, laboratories and long-term care homes in Ontario are required by law to report infectious diseases to the public health unit in their area. As part of its mandate, the Haliburton, Kawartha, Pine Ridge (HKPR) District Health Unit investigates cases of infectious diseases and works with other agencies to control outbreaks. This service is one of the many public health programs provided by the HKPR District Health Unit to residents of Haliburton County, Northumberland County and the City of Kawartha Lakes. The HKPR region, with its approximate 170,000 population, encompasses a large part of Central Ontario. The HKPR District Health Unit has prepared this report, Infectious Diseases Within the HKPR District, to outline incidence rates of eight most common infectious diseases within its region between 2000 and 2008. Statistics for the HKPR region are also compared with disease data for all of Ontario and Canada. Key Findings A list of infectious diseases included in this report, as well as a snapshot of their rates over the past decade in the HKPR region, are provided below: Campylobacteriosis • Between 2000 and 2008, the campylobacteriosis rate for the HKPR region was much lower than the provincial number. However, 2005 is an exception, and this might have may resulted from two campylobacteriosis outbreaks reported in the area that year. Chlamydia • Rates of chlamydia have been increasing in the HKPR region since 2000. This rising trend is reflected in rates for Canada between 1989 and 2004, and for Ontario from 2000 to 2008. 2 Cryptosporidiosis • Over the past decade, cryptosporidiosis rates in the HKPR region peaked in 2006, then declined during the subsequent two years. Rates for Ontario have remained consistent from 2000 to 2008. Giardiasis • In recent years, cases of giardiasis have been in steady decline across Ontario and Canada. A similar trend was observed in the HKPR region from 2000 to 2004, with slight variations in giardiasis rates during the subsequent four years. Hepatitis C • Since 2002, the rate of Hepatitis C in the HKPR region has remained slightly above the provincial rate. This may be due in part to the presence of large correctional facilities in this area. Influenza • A marked increase in influenza cases within the HKPR region was recorded during the 2004/05, 2006/07 and 2007/08 flu seasons, reflecting a similar jump in rates for Canada and Ontario in those years. Salmonellosis • Between 2000 and 2008, the number of salmonellosis cases reported in the HKPR region tended to mirror the provincial rate for the same time period. Locally, a peak in salmonellosis cases was observed in 2006, although a common source of infection was not identified. Streptococcal Pneumoniae Disease • Streptococcal pneumoniae Disease or Invasive Pneumococcal Disease (IPD) was added to the list of reportable diseases in 2002. From 2003 to 2008, the provincial rate remained relatively stable. Within the HKPR region, the IPD cases in the HKPR region have gone up and down between 2002 and 2008, with numbers peaking in 2007. More detailed statistics and graphs for each of these infectious diseases are provided in the full report. 3 Introduction Health units in Ontario are required by law to track the spread of infectious diseases within their regions, including trends and the risk to public health. According to the Health Protection and Promotion Act, health care providers, laboratories and long-term care homes must report certain infectious diseases to their local Health Unit. Staff with the Health Unit will investigate these cases and work with other agencies to control any outbreaks. The Health Unit is also responsible for reporting these diseases to the Ontario Ministry of Health and Long-Term Care. The Haliburton, Kawartha, Pine Ridge (HKPR) District Health Unit is continuously tracking and investigating infectious diseases in Haliburton County, Northumberland County and the City of Kawartha Lakes. This report, Infectious Diseases Within the HKPR District, provides an overview and statistics of certain diseases reported in the region between 2000 and 2008. It also compares disease data for this region with national and provincial rates. An analysis of the following reportable diseases is provided: • • • • • • • • Campylobacteriosis Chlamydia Cryptosporidiosis Giardiasis Hepatitis C Influenza Salmonellosis Streptococcal Pneumoniae Disease Note: When interpreting this data, consider that the number of cases of a disease reported to the Health Unit may not reflect its true extent. For many reportable diseases, only a small percentage of individuals who have symptoms seek medical attention and receive testing in the lab. Those diseases with fewer than 5 cases reported annually were not included in this report. 4 Campylobacteriosis Description Campylobacteriosis is the most common bacterial infection in the world. People can become ill from it when they eat undercooked meat, drink contaminated water and consume unpasteurized milk. Campylobacteriosis can also be spread to humans when they come in contact with infected animals (including pets) and contaminated surfaces such as cutting boards, counters and utensils. Children under the age of five years and young adults have the highest occurrence of this infection. People with compromised immune systems are also at a greater risk. Symptoms Symptoms of campylobacteriosis include diarrhea, abdominal pain, fatigue, fever, nausea and vomiting. These symptoms usually appear between two and 10 days after initial exposure to the bacteria. Symptoms can range from mild to severe, and may be recurring. Complications from the disease may occur, including typhoid-like syndrome, arthritis, convulsions, and meningitis (inflammation of the lining of the brain). Another complication is Guillain-Barré Syndrome, a potentially life-threatening illness that causes progressive weakness and paralysis. Prevention and Control To reduce the risk of campylobacteriosis, thoroughly cook meat and poultry. In the kitchen, clean work surfaces to ensure raw or undercooked meat does not come into contact with ready-to-eat foods. People who work with domestic animals should also use proper hand hygiene at all times. Data Trends In Canada from 1989 to 2004, campylobacteriosis was the most frequently reported enteric illness. However during this time period, there was a decreasing trend in the illness provincially and across Canada. The following graph shows the number of cases of campylobacteriosis in the HKPR District Health Unit region between 2000 and 2008. The HKPR rate shows a similar trend, except for the year 2005 when the incidence rate peaked locally at 45 cases per 100,000 population. 5 Number of Campylobacter enteritis cases in HKPR District Health Unit region, 2000-2008 Number of confirmed cases 100 80 60 40 20 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 Calendar year Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 The following graph compares the local and provincial rates of campylobacteriosis cases between 2000 and 2008. In most years, the rate for the HKPR region is much lower than the provincial number. However, 2005 is an exception, and this may result from two campylobacteriosis outbreaks reported in the HKPR region that year. Incidence rates of Campylobacter enteritis in HKPR District Health Unit region in comparison to Ontario rates 50.0 45.0 40.0 35.0 Rate 30.0 25.0 20.0 15.0 10.0 HKPR rate 5.0 0.0 ON rate 2000 2001 2002 2003 2004 2005 2006 2007 2008 HKPR rate 31.0 40.8 29.5 34.3 27.6 45.2 25.7 33.1 27.7 ON rate 42.0 44.0 38.0 33.2 32.8 29.5 30.0 30.1 29.2 Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 Reportable disease data posted on Public Health Ontario Portal Population estimates and projections. 2000-08. Ontario MOHLTC, extracted from Intellihealth July 2009 6 While further analysis by age, gender and seasonality was not completed, the number of reported cases of campylobacteriosis peaks during the warmer months. This is due to people having greater contact with environmental sources of contamination and increased exposure to high-risk foods at this time of year. References Heymann DL. (2004). Control of Infectious Diseases Manual, 18th edition. Washington, DC: American Public Health Association. P.81-84. Public Health Agency of Canada. Campylobacteriosis –Notifiable Diseases On-Line. Cited July 3rd, 2009 from <http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/diseases/camp-eng.php> Public health Agency of Canada. Notifiable Diseases On-Line – Chart Query Result: Campylobacteriosis, both Sexes Combined, All Ages, Canada 1989 – 2004. Cited July 3rd, 2009 from < http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/cgibin/ndischart2?DATA_TYPE=R&YEAR_FROM=89&YEAR_TO=04&CAUSE=086& AREA=00&AGE=0&SEX=3&CTIME1=View+Chart> 7 Chlamydia Description Chlamydia trachomatis infections are one of the most common sexually transmitted infections (STIs). These infections occur around the world, and are spread through sexual intercourse. Symptoms Most infected people show no symptoms of chlamydia. Up to 70 per cent of women, and 10 to 25 per cent of men, may be unaware they are infected with it. The main symptom of chlamydia in men is urethritis, while among females it is cervical infection. Chlamydia has similar symptoms to gonorrhea, such as moderate or small amounts of discharge, itching in the urethra and a burning sensation when urinating. Women may also experience lower abdominal pain and abnormal vaginal bleeding between periods. If left untreated in women, chlamydia infections can lead to pelvic inflammatory disease, problematic pregnancies, infertility and chronic pain in the pelvic area. Chlamydia rates among sexually-active youth can range from 15 to 25 per cent. Prevention and Control Practising safer sex, using condoms and limiting the number of sexual partners are all important ways to prevent chlamydia. Young women should be screened regularly for chlamydia, especially when they become pregnant. Early diagnosis and treatment is key to controlling the infection, as is notifying any sexual partner who could be at risk. Data Trends Genital chlamydia is the most commonly reported STI, with rates rising steadily across Canada between 1989 and 2004, and in Ontario from 2000 to 2008. The HKPR region has seen a similar increase since 2000, as shown in the following graph. 8 Number of Chlamydia cases in HKPR District Health Unit region, 2000-2008 Number of confirmed cases 220 200 180 160 140 120 100 80 60 40 20 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 Calendar year Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 The incidence rate of chlamydia varies significantly between age groups. This makes age standardization necessary to compare local and provincial rates. Age standardization is used to compare incidence rates of disease between populations with different age distributions. For example, STIs such as chlamydia are more common among 15-to-24 year olds. Consequently, a population with a higher proportion of this age group will have a higher overall incidence rate of STIs. To determine which population has a higher incidence rate regardless of age distribution, the rates must be age standardized. Using age standardization rates as shown below, the HKPR region has a lower chlamydia rate than the rest of Ontario since 2000. 9 Age-Standardized Incidence rates (Per 100,000 population) Age Standardized Incidence Rate of Chlamydia in HKPR District Health Unit region and Ontario, 2000-2008 250 200 150 100 50 ON 0 2003 2004 2005 HKPR 2000 2001 2002 2006 2007 2008 ON 140.5 152.4 170.9 180.2 189.7 195.4 199.2 201.9 226.5 HKPR 40.7 63.7 96.2 126.4 157.9 168.7 179.9 162.3 160.1 Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 Reportable disease data posted on Public Health Ontario Portal Population estimates and projections. 2000-08. Ontario MOHLTC, extracted from Intellihealth July 2009 References Heymann DL. (2004). Control of Infectious Diseases Manual, 18th edition. Washington, DC: American Public Health Association. P.100-103. Public Health Agency of Canada. Genital Chlamydiosis –Notifiable Diseases On-Line. Cited July 3rd, 2009 from < http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/diseases-maladies/chlamyd-eng.php> Public health Agency of Canada. Notifiable Diseases On-Line – Chart Query Result: Genital Chlamydiosis, both Sexes Combined, All Ages, Canada 1989 – 2004. Cited July 3rd, 2009 from < http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/cgibin/ndischart2?DATA_TYPE=R&YEAR_FROM=89&YEAR_TO=04&CAUSE=138& AREA=00&AGE=0&SEX=3&CTIME1=View+Chart> 10 Cryptosporidiosis Description Cryptosporidiosis is a condition caused by a parasite known as Cryptosporidium parvum. A person can develop this condition by ingesting food or water that has become contaminated with feces. This ‘fecal oral route’ is one of the main ways that people get sick from cryptosporidiosis. Direct person-to-person, or animal-to-person transmission, may also occur. Outbreaks of cryptosporidiosis are often linked to consuming unsafe drinking water or swallowing contaminated water from a lake, river or swimming pool. People who are at a greater risk of cryptosporidiosis include very young children, travelers, animal handlers, people with compromised immune systems and men who have sex with men. Symptoms Diarrhea is a major symptom, and is usually combined with cramping and abdominal pain. Other symptoms include weight loss, anorexia and nausea. In certain cases, no visible symptoms may be present. Prevention and Control Proper handwashing is the most effective way to prevent the spread of cryptosporidiosis. Boiling drinking water is advisable if there is a concern about water quality. Individuals who show symptoms of cryptosporidiosis should stay home, especially if they work with children or prepare food. To reduce person-to-person and animal-to-person transmission, personal hygiene and the safe disposal of feces should be emphasized. Data Trends Cryptosporidiosis rates in Canada remained steady between 2000 and 2004, with one exception. In 2001, a spike in cases was attributed to a waterborne cryptosporidiosis outbreak in Saskatchewan. In Ontario, the rate has remained consistent from 2000 to 2008. Cryptosporidiosis rates in the HKPR region peaked in 2006, and then declined during the subsequent two years. The following graph provides more detail on local cryptosporidiosis cases. 11 Number of confirmed cases Number of Cryptosporidiosis cases in HKPR District Health Unit region, 2000 - 2008 20 16 12 8 4 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 Calendar year Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 In the graph below, a comparison of local and provincial cryptosporidiosis rates is provided. Incidence rates of Cryptosporidiosis in HKPR District Health Unit region in comparison to Ontario rates 10 9 8 7 Rate 6 5 4 3 2 1 0 HKPR rate ON rate 2000 2001 2002 2003 2004 2005 2006 2007 2008 HKPR rate 1 4.3 4.7 5.8 5.7 5.2 8.6 5.0 4.0 ON rate 2 2 2 2.2 2.4 2.1 3.1 3.1 2.6 Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 Reportable disease data posted on Public Health Ontario Portal Population estimates and projections. 2000-08. Ontario MOHLTC, extracted from Intellihealth July 2009 Cryptosporidiosis rates in the HKPR region were consistently higher than the provincial numbers (further analysis based on age, sex or seasonality was not completed). A jump in local cases during 2006 reflects the increase in cryptosporidiosis cases reported that year in Ontario. Using early warning data, a provincial investigation into cryptosporidiosis found an increase in reported cases during August 2006. However, a common exposure or risk factor was not identified. 12 References Heymann DL. (2004). Control of Infectious Diseases Manual, 18th edition. Washington, DC: American Public Health Association. P.138-141. Public Health Agency of Canada. Cryptosporidium parvum – Material Safety Data Sheet (MSDS). [Online] Cited July 3rd, 2009 from http://www.phac-aspc.gc.ca/msds-ftss/msds48e-eng.php Public health Agency of Canada. Notifiable Diseases On-Line – Chart Query Result: Cryptosporidiosis, both Sexes Combined, All Ages, Canada 1989 – 2004. Cited July 3rd, 2009 from < http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/cgibin/ndischart2?DATA_TYPE=R&YEAR_FROM=89&YEAR_TO=04&CAUSE=176& AREA=00&AGE=0&SEX=3&CTIME1=View+Chart> Dalloo A, Lacroix C. (2007) Cryptosporidiosis Investigation in Ontario – October 2006. Canadian Field Epidemiology Program. Ottawa, ON. 13 Giardiasis Description Giardiasis is caused by the parasite Giardia lamblia. While this parasite can be found in animal and human feces, it also thrives in warm, still bodies of water such as ponds and stagnant lakes. The infection is mainly spread when an object such as food or water becomes contaminated with feces, and is then ingested by an individual. Giardiasis occurs worldwide in areas of poor sanitation. In North America, it is common in childcare centres where children are not yet toilet-trained. Symptoms Symptoms include chronic diarrhea, abdominal cramps and bloating, fatigue and weight loss. Complications such as arthritis and damage to cells that line the intestine can also result from giardiasis, especially in cases of prolonged infection. Prevention and Control Proper hand hygiene and avoiding contaminated water sources are the best ways to prevent giardiasis. If individuals show symptoms of the infection, they should not use swimming pools, water slides, hot tubs and other recreational water settings frequented by others. If drinking water supplies are exposed to human or animal fecal contamination, they should be filtered, cleaned and chlorinated before use to reduce the risk of infection. Data Trends In recent years, cases of giardiasis have been in steady decline across Ontario and Canada. A similar trend was observed in the HKPR region from 2000 to 2004, with slight variations in giardiasis rates during the subsequent four years. However, the number of giardiasis cases reported in the HKPR region in 2008 is significantly lower when compared to the year 2000. The following graph provides more details on local rates of the infection. 14 Number of confirmed cases Number of Giardiasis cases in HKPR District Health Unit region, 2000-2008 50 45 40 35 30 25 20 15 10 5 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 Calendar year Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 In the graph below, incidence rates for giardiasis are compared between Ontario and the HKPR region. Because of the variability in local rates, it is difficult to determine whether the trend is significantly different than the Ontario rates. Incidence rates of Giardiasis in HKPR District Health Unit region in comparison to Ontario rates 30.0 25.0 Rate 20.0 15.0 10.0 5.0 0.0 2000 2001 2002 2003 2004 2005 2006 2007 2008 HKPR rate 24.0 24.1 9.4 10.5 12.6 14.9 9.7 19.4 13.0 ON rate 17.0 18.0 16.0 13.2 12.6 12.7 12.1 12.5 12.1 Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 Reportable disease data posted on Public Health Ontario Portal Population estimates and projections. 2000-08. Ontario MOHLTC, extracted from Intellihealth July 2009 15 References Heymann DL. (2004). Control of Infectious Diseases Manual, 18th edition. Washington, DC: American Public Health Association. P.229-231. Public Health Agency of Canada. Giardiasis –Notifiable Diseases On-Line. Cited July 3rd, 2009 from <http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/diseases/giar-eng.php> Public Health Agency of Canada. Giardia lamblia – Material Safety Data Sheet (MSDS). (Online) Cited July 3rd, 2009 from <http://www.phac-aspc.gc.ca/msds-ftss/msds71eeng.php> Public Health Agency of Canada. Notifiable Diseases On-Line – Chart Query Result: Giardiasis, both Sexes Combined, All Ages, Canada 1989 – 2004. Cited July 3rd, 2009 from < http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/cgibin/ndischart2?DATA_TYPE=R&YEAR_FROM=89&YEAR_TO=04&CAUSE=043& AREA=00&AGE=0&SEX=3&CTIME1=View+Chart> 16 Hepatitis C Description Hepatitis C Virus (HCV) is a bloodborne infectious disease. While Hepatitis C cases occur around the world, its existence was only proven conclusively in 1989. HCV can cause inflammation of the liver and, over time, lead to cirrhosis (extensive scarring that affects liver function). Exposure to blood or blood products infected with HCV is the main way it is spread to others. Injection drug users, hemophilia patients and hemodialysis patients have a higher risk of infection. Rates of HCV infection were also higher among recipients of blood, tissues and other organs prior to 1990. Since then, a major improvement in screening procedures used to detect the infection in blood products has been implemented. In Canada, 10 to 20 new cases of HCV per 100,000-population are reported each year. Symptoms The majority of people with HCV show no symptoms. Those who do will typically experience symptoms six to seven weeks after infection. Jaundice (yellowing of the skin and eyes) can occur in 20 to 30 per cent of HCV cases. Other symptoms can include feeling of uneasiness, loss of appetite, stomach pain, fatigue and dark urine. Approximately one-quarter of individuals who are infected with acute Hepatitis C recover without the need for treatment. Annually, one per cent to five per cent of people who are infected will HCV die from chronic liver disease, liver damage and liver cancer. Prevention and Control Limiting exposure to contaminated blood or blood products and encouraging the use of sterile needles are the best ways reduce the risk of HCV. Equipment used for tattoos, body piercing and acupuncture should be sterilized. Homemade or reused equipment such as needles and ink should be avoided. Data Trends National rates of HCV decreased from 1998 to 2004. In Ontario, HCV rates dropped from 49 cases per 100,000-population in the year 2000 to 35 cases per 100,000population in 2008. In the HKPR region, Hepatitis C cases rose slightly from 2000 to 2004, and have since been in decline. The following graph gives a detailed year-by-year breakdown of local HCV rates for the 2000 to 2008 period. 17 Number of confirmed cases Number of Hepatitis C cases in HKPR District Health Unit region, 2000-2008 150 135 120 105 90 75 60 45 30 15 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 Calendar year Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 The graph below compares the HCV rates for the HKPR region and the rest of Ontario from 2000 to 2008. Since 2002, the local rate of HCV has remained slightly above the provincial rate, and this may be due to the presence of large correctional facilities in this area. Incidence rates of Hepatitis C in HKPR District Health Unit region in comparison to Ontario rates 120.0 100.0 Rate 80.0 60.0 40.0 20.0 HKPR rate ON rate 0.0 2000 2001 2002 2003 2004 2005 2006 2007 2008 HKPR rate 36.0 43.9 51.0 65.0 71.0 59.0 54.8 57.0 45.1 ON rate 49.0 48.3 45.0 44.0 42.8 36.1 29.5 35.1 35.5 Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 Reportable disease data posted on Public Health Ontario Portal Population estimates and projections. 2000-08. Ontario MOHLTC, extracted from Intellihealth July 2009 Note: Increased lab testing for HCV between 2000 and 2008 resulted in a significant rise in the number of cases reported in Ontario. These represent 'newly-diagnosed' cases, both acute cases (infection has been acquired within a few weeks) and chronic cases (infection has been present for several months or years). Figures in the graph do not reflect the 18 under-reporting and newly-infected cases of Hepatitis C. As a result, these numbers should be interpreted with caution. References Heymann DL. (2004). Control of Infectious Diseases Manual, 18th edition. Washington, DC: American Public Health Association. P.261-264. Public Health Agency of Canada. 2003. Hepatitis C Fact Sheet – Bloodborne pathogens Section, Blood Safety Surveillance and Health Care Acquired Infections Division. [Online] Cited on July 3, 2009 from < http://www.phac-aspc.gc.ca/hcai-iamss/bbp-pts/hepatitis/hep_c-eng.php> Public health Agency of Canada. Notifiable Diseases On-Line – Chart Query Result: Campylobacteriosis, both Sexes Combined, All Ages, Canada 1989 – 2004. Cited July 3rd, 2009 from < http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/cgibin/ndischart2?DATA_TYPE=R&YEAR_FROM=89&YEAR_TO=04&CAUSE=173& AREA=00&AGE=0&SEX=3&CTIME1=View+Chart> 19 Influenza Description Influenza, also known as the ‘flu,’ is a serious respiratory infection that begins in a person’s nose and throat. It is highly contagious and spreads rapidly from person-toperson through coughing or sneezing, and by touching contaminated surfaces such as doorknobs, telephones and eating utensils. Influenza, which is caused by the A, B or C types of influenza virus, usually occurs on a seasonal basis, typically in Canada between November and April. The influenza virus can also mutate so that is becomes more virulent, and this can result in an epidemic or a more widespread pandemic. Symptoms People who get influenza can suffer from fever, chills, cough, runny eyes, stuffy nose, sore throat, headache, muscle aches, extreme weakness and fatigue. The cough is often severe and prolonged. In more severe cases, influenza can lead to pneumonia and even cause death. People who are at greater risk of influenza include elderly people and those with compromised immune systems. Prevention and Control Getting immunized each year is the best defence against influenza, as it can provide 70 to 80 per cent protection against infection. The effectiveness of the influenza vaccine may vary based on the age of the person being immunized, the immunity level of the recipient, and how well the vaccine matches the strain of influenza circulating in the community that year. Educating people, especially health care workers, about the importance of regular and thorough hand washing, covering up coughs and sneezes, and staying home from work when sick are also effective ways to help reduce the spread of influenza. Data Trends Note: Because most influenza cases occur from November to April in Canada, surveillance data is compiled annually from September 1 to August 31 of the following year. This is the time period referred to in the following statistics and graphs. Between 2000/01 and 2007/08, influenza activity in the HKPR District Health Unit region showed a wide variation. A marked increase in local influenza cases was recorded during the 2004/05, 2006/07 and 2007/08 flu seasons, reflecting a similar jump in rates for Canada and Ontario in those years. The increased influenza activity for these years may reflect only a partial match between the circulating virus strain and the vaccine available in that flu season. 20 The following graph shows the number of lab-confirmed influenza cases reported in HKPR District Health Unit region between 2000-01 and 2007-2008. Number of Influenza cases reported at HKPR District Health Unit region, 2000 - 01 to 2007- 08 Number of confirmed cases 160 140 120 100 80 60 40 20 0 2000-01 2001-02 2002-03 2003-04 2004-05 2005-06 2006-07 2007-08 Calendar year Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 The graph below compares influenza rates between Ontario and the HKPR District Health Unit region from 2000/01 to 2007/08. After 2002/03, the local incidence rate of influenza is consistently higher than the rest of the province. During the last three flu seasons in the HKPR region, children under 14 years of age and individuals aged 65 years and older were most frequently diagnosed with influenza. 21 Incidence rates of Influenza rates in HKPR District Health Unit region in comparison to Ontario rates, 2000- 01 to 2007- 08 90.0 80.0 70.0 Rate 60.0 50.0 40.0 30.0 20.0 10.0 0.0 HKPR rate ON rate 2000-01 2001-02 2002-03 2003-04 2004-05 2005-06 2006-07 2007-08 HKPR rate 9.5 6.8 6.5 68.7 80.5 60.8 80.0 77.6 ON rate 8.1 19.4 8.3 43.1 47.0 19.9 22.5 41.7 Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 Reportable disease data posted on Public Health Ontario Portal Population estimates and projections. 2000-08. Ontario MOHLTC, extracted from Intellihealth July 2009 Data Notes: The proportion of people 65 years and older living in HKPR District Health Unit region compared to Ontario is different. This maybe one of the reasons for an increased rate when compared to Ontario, as the majority of cases occurring in HKPR District Health Unit region are 65 years and older. Age standardization is necessary to compare incidence rates of disease between populations with different age distributions. Due to the unavailability of the provincial data by age group, comparison of the age-standardized rates was not possible. Hence the interpretation of the comparison with the provincial rate should be done with caution, understanding the variability in the age distribution. References Heymann DL. (2004). Control of Infectious Diseases Manual, 18th edition. Washington, DC: American Public Health Association. P.281-287. Public Health Agency of Canada. 2008-2009 FluWatch. [online] Cited July 3rd, 2009 from <http://www.phac-aspc.gc.ca/fluwatch/index-eng.php> Public Health Agency of Canada. Notifiable Diseases On-Line – Chart Query Result: Influenza, laboratory confirmed, both Sexes Combined, All Ages, Canada 1989 – 2004. Cited July 3rd, 2009 from < http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/cgibin/ndischart2?DATA_TYPE=R&YEAR_FROM=89&YEAR_TO=04&CAUSE=058& AREA=00&AGE=0&SEX=3&CTIME1=View+Chart> 22 Salmonellosis Description Salmonellosis is caused by bacteria from the Salmonella family, and is mainly transmitted through contaminated food. This can occur if someone eats undercooked poultry, raw milk and eggs, or food that becomes contaminated during preparation. Another way that salmonellosis can be spread is by people coming into direct or indirect contact with certain animals, including common pets such as birds, reptiles, turtles and tortoises. Symptoms Symptoms of salmonellosis include the onset of headache, abdominal pain, diarrhea, and nausea. These symptoms usually occur 12 to 48 hours after someone eats contaminated food or drinks. Dehydration, especially among young children, elderly people and individuals with compromised immune systems, can be severe and result in people being hospitalized. Prevention and Control Salmonellosis infection can be prevented when you wash your hands well and follow safe food practices. Food safety includes chilling food properly, washing produce thoroughly, separating raw foods from other foods, and cooking foods to safe internal temperatures. Data Trends From 1989 to 2004, salmonellosis rates in Canada showed a gradual decline. The following graph shows the number of salmonellosis cases reported in the HKPR District Health Unit region between 2000 and 2008. Locally, a peak was observed in 2006, although a common source of infection was not identified. 23 Number of Salmonellosis cases in HKPR District Health Unit region, 2000 - 2008 Number of confirmed cases 50.0 40.0 30.0 20.0 10.0 0.0 2000 2001 2002 2003 2004 2005 2006 2007 2008 Calendar year Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 In the graph below, the incidence rates of salmonellosis in the HKPR region is compared with the rest of Ontario for the years 2000 to 2008. The two rates tend to mirror each other over time, although the local numbers remain slightly lower than the provincial rate. Incidence rates of Salmonellosis in HKPR District Health Unit region in comparison to Ontario rates 50.0 45.0 40.0 Rate 35.0 30.0 25.0 20.0 15.0 10.0 5.0 0.0 HKPR rate ON rate 2000 2001 2002 2003 2004 2005 2006 2007 2008 HKPR rate 26.0 27 16 15 16.7 21.8 25.2 12.0 11 ON rate 20.0 22.0 20.0 16.2 17.0 23.32 18.50 21.92 18.4 Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 Reportable disease data posted on Public Health Ontario Portal Population estimates and projections. 2000-08. Ontario MOHLTC, extracted from Intellihealth, July 2009 24 References Heymann DL. (2004). Control of Infectious Diseases Manual, 18th edition. Washington, DC: American Public Health Association. P.469-473. Public Health Agency of Canada (2001). Material Safety Data Sheet: Salmonellosis. [Online] Cited July 3, 2009 from: < http://www.phac-aspc.gc.ca/msds-ftss/msds135e-eng.php> Public health Agency of Canada. Notifiable Diseases On-Line – Chart Query Result: Salmonellosis, both Sexes Combined, All Ages, Canada 1989 – 2004. Cited July 3rd, 2009 from < http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/cgibin/ndischart2?DATA_TYPE=R&YEAR_FROM=89&YEAR_TO=04&CAUSE=108& AREA=00&AGE=0&SEX=3&CTIME1=View+Chart> 25 Streptococcal Pneumoniae Disease, Invasive Description This is a severe respiratory illness also known as Invasive Pneumococcal Disease (IPD). The disease is caused by a type of bacteria called Streptococcus pneumoniae, and can be deadly for infants and elderly people. Bacteria that cause IPD can live at the back of the nose and throat without causing symptoms. The bacteria are spread through droplets in the air when an infected person coughs or sneezes. Bacteria can also be transmitted through the saliva of an infected person who shares common items such as bottles, straws and eating utensils. Symptoms Symptoms of IPD include the sudden onset of a high fever, chills, headache, tiredness, coughing, and chest pain/discomfort. Among infants and young children, fever, vomiting and convulsions are initial signs of IPD. The bacteria that cause IPD can also result in pneumonia (lung infection), bacteraemia (infection of the blood) and meningitis (infection of the lining of the brain and spinal cord). These conditions can be deadly and may cause long-lasting complications such as deafness, especially in people with existing medical conditions. Prevention and Control Vaccination is the best way to protect people from Invasive Pneumococcal Disease. As part of its publicly-funded immunization program, Ontario provides vaccine free of charge to children under six years of age, as well as to individuals of all ages with specified medical conditions. Free vaccination is also available to those 65-years-of-age or older, and individuals who live in nursing homes, homes for the aged, and chronic-care facilities or wards. Crowded living quarters in large institutions or barracks should be discouraged, as this contributes to the spread of disease. In some cases, the use of antibiotics can make individuals less infectious. Data Trends While there was a sharp decline in the national rate of Streptococcal Pneumoniae Invasive Disease in 2001, numbers increased from 2002 to 2004. In Ontario, the disease was added to the list of reportable diseases in 2002 and, between 2003 and 2008, the provincial rate remained relatively stable. From 2002 to 2008, the number of invasive Streptococcal pneumonia cases in HKPR region disease has had multiple peaks and valleys, as reflected in the graph below. 26 Number of Streptococcus pneumoniae invasive cases in HKPR District Health Unit region, 2002 - 2008 Number of confirmed cases 25 20 15 10 5 0 2002 2003 2004 2005 2006 2007 2008 Calendar year Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 The next graph compares the rate of invasive Streptococcal pneumoniae in the HKPR region and Ontario from 2002 to 2008. In most years, the local rate was slightly higher. Incidence rates of Streptococcus pneumoniae invasive in HKPR District Health Unit region in comparison to Ontario rates Incidence Rate per 100,000 population 15.0 10.0 5.0 0.0 2002 2003 2004 2005 2006 2007 2008 HKPR rate 7.7 9.3 9.8 10.3 6.3 12.6 10.2 ON rate 5.10 8.1 8.5 7.31 7.40 7.35 8.08 Data Sources: integrated Public Health Information System (iPHIS), extracted July 2009 Reportable disease data posted on Public Health Ontario Portal Population estimates and projections. 2000-08. Ontario MOHLTC, extracted from Intellihealth July 2009 References Heymann DL. (2004). Control of Infectious Diseases Manual, 18th edition. Washington, DC: American Public Health Association. P.413-417. 27 Public Health Agency of Canada. Streptococcus pneumoniae – Material Safety Data Sheet (MSDS). [Online] Cited July 15, 2009 from <http://www.phac-aspc.gc.ca/msdsftss/msds147e-eng.php> Public health Agency of Canada. Notifiable Diseases On-Line – Chart Query Result: Invasive pneumococcal disease, both Sexes Combined, All Ages, Canada 1989 – 2004. Cited July 3rd, 2009 from < http://dsol-smed.phac-aspc.gc.ca/dsol-smed/ndis/cgibin/ndischart2?DATA_TYPE=R&YEAR_FROM=89&YEAR_TO=04&CAUSE=182& AREA=00&AGE=0&SEX=3&CTIME1=View+Chart> Publicly funded immunization schedules for Ontario, January 2009. 28 GLOSSARY Age Standardized Incidence Rate The incidence rate that a population would have if it had a standard age distribution. Age standardization is used to compare incidence rates of disease between populations with different age distributions. E.g. Sexually transmitted infections (STIs) such as chlamydia are more common among 15-to-24 year olds, so a population with a higher proportion of this age group will have a higher overall incidence rate. In order to determine which population has a higher incidence rate regardless of age distribution, the rates must be age standardized. Bacteria Single cell microorganisms, some of which cause infections and disease in humans. Database A collection of data arranged for ease and speed of retrieval. Disease An unhealthy condition of the body or mind, such as an illness or sickness. Epidemic This occurs when new cases of a certain disease, in a given human population, and during a given period, substantially exceeds what is "expected” based on recent experience (the number of new cases in the population during a specified period of time). Immunity State of being protected against infectious disease. Incidence The number of new cases of disease occurring during a defined time period in a defined population. Incidence Rate The rate at which new cases of disease occur in a defined population during a defined time period. The incidence rate is the number of new cases of disease relative to the total population at risk, and is usually expressed as number of cases per 100,000 people. Infection This describes the entry and development, or multiplication, of an infectious organism in the body. A person can become infected, but not experience any disease. 29 Infectious Agent An organism that is capable of causing infection (E.g. bacteria, viruses or parasites). Invasive Penetrates sites such as tissues, blood or cerebrospinal fluid. Microorganism An organism of microscopic or submicroscopic size. Outbreak An increase in incidence of a disease above expected levels. Pandemic A pandemic is an epidemic of infectious diseases that is spreading through human populations across a large region, such as a continent or around the world. Pathogen This is a microorganism that causes disease, including bacteria, viruses, or parasites. Pneumonia It is an inflammation or infection of the lungs most commonly caused by a bacteria or virus. Prevalence The number of existing cases of disease or health condition at a particular time and in a defined population. Reportable Disease Reportable diseases are defined in Ontario's Health Protection and Promotion Act as infectious diseases (or suspected occurrences of these diseases) that must be reported to local health units by health care providers, laboratories and administrators of institutions such as long-term care homes. Health units must in turn report these diseases to the Ministry of Health and Long-Term Care. Sexual Contact Sexual intercourse or other intimate sexual contact. Significant Unlikely to have occurred by chance. Vaccination The introduction of vaccine into the body for the purpose of inducing immunity. 30 Vector Organisms that transmit human disease or play an essential role in the life cycle of a pathogenic agent. Virus Microorganism consisting of DNA or RNA and a protein coat. Viruses invade host cells to survive and can cause infection and disease in humans. 31