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How to Manage the Patient with Hemodynamic Support: Trouble-Shooting David M. Shavelle MD FACC FSCAI Associate Clinical Professor Keck School of Medicine at USC Director, General Cardiology Fellowship Director, Cardiac Catheterization Laboratory Los Angeles County + USC Medical Center Objectives Discuss common issues related to IABP, Tandem Heart and Impella: 1. Device insertion 2. Device malfunction 3. Device removal “I embrace solutions, not excuses” Jon Taffer, BAR RESCUE Device Insertion Case 1 68 yo male with ischemic cardiomyopathy, prior CABG, prior PCI, EF 10% admitted with decompensated heart failure. IABP placed in cath lab with initial augmentation of 120 mm Hg on Dopamine 5 mcg/kg/min. The patient is transferred to the ICU and the nurse calls stating IABP is ‘not working’ and is no longer providing an augmentation of the BP. The next best step in management would be: 1. Add Milrinone 0.25 mcg/kg/min 2. Increase Dopamine to 20 mcg/kg/min 3. Portable Chest Ray 4. Consider Impella Device Case 1 68 yo male with ischemic cardiomyopathy, prior CABG, prior PCI, EF 10% admitted with decompensated heart failure. IABP placed in cath lab with initial augmentation of 120 mm Hg on Dopamine 5 mcg/kg/min. The patient is transferred to the ICU and the nurse calls stating IABP is ‘not working’ and is no longer providing an augmentation of the BP. The next best step in management would be: 1. Add Milrinone 0.25 mcg/kg/min 2. Increase Dopamine to 20 mcg/kg/min 3. Portable Chest Ray 4. Consider Impella Device Movement of IABP • Device placed on standby • Advance based upon estimate of distance • Recheck chest X ray Optimal Device Placement: IABP • Radio-opaque tip at proximal portion of IABP • Optimal position: tip distal to left subclavian artery in proximal descending aorta • Common Issues Unable to see on Xray over penetrate film palpate left radial and/or brachial pulse may need fluroscopy Ability to move IABP allow ‘slack’ at groin Problem: Aorto-iliac Disease • • • • • Indentify during initial arterial access Difficult to place .025” wire Access with floppy or hydrophilic wire (Benson, Wholey, Magic Torque, Glide) exchange using catheter (glide catheter, JR4, MP, etc) for IABP .025” wire Consider angiography, PTA and stent placement to facilitate IABP passage If stent placed, fluroscopy essential during IABP advancement through stent Problem: No Femoral Access • • • • Impella and TH not possible IABP Alternative access sites: left brachial & left subclavian arteries Axillary artery also possible Described in heart failure/transplant literature for prolonged access to keep patients ambulatory (frequently with conduits) Left Brachial Artery Access • 68 yo male, EF 20%, ongoing CHF, severe LM/LAD disease, Aortoiliac occlusion, refused CABG • Ht 6’ 6”, Wt 84 kg • Ultrasound left brachial artery: Ø 5 mm • Punctured and 8F sheath inserted for 50 cc Mega IABP • Removed at end of case with manual compression Left brachial fossa with 50 cc Mega via sheath Device Insertion: Tandem Heart • Transseptal puncture: lost art, not trained during IC fellowship very difficult to achieve necessary skills • Current fellows partner with EP program for afib cases • Puncturing the septum – 3 approaches • Fluroscopic – anatomic landmarks • ICE guided • TEE guided • Regardless of method: meticulous technique, go slow, measure pressures during puncture (not done by majority of EP doctors), use contrast to define anatomy • Reference = Daoud E Heart Rhythm Vol 2 No 2 Feb 2005 Device Insertion: ICE Guidance ICE catheter and BB needle Clear tenting of IAS Daoud E Heart Rhythm Vol 2 No 2 Feb 2005 Device Insertion: TEE Guidance Clear tenting of mid IAS LA cannulae in place Anesthesia & Analgesia. 103(6):1412-1413, December 2006 Optimal Device Placement: TH .035” Amplatzer wire Mullins TS sheath Standard wire = Amplatz ES or SS or Amplatzer J wire .025” Inoue wire Additional support Rarely, IAS needs to be dilated with 4 mm balloon to facilitate cannulae placement Optimal Device Placement: TH Insert movie name = JC8 Left Atrial Gram via Mullins TS sheath Insert movie name = JC7 Tandem Heart 21 F venous cannulae in left atrium Optimal Device Placement: TH • Radio-opaque markers on tip of venous cannulae • Observe venous cannulae position • Cannulae can move/entrain into the pulmonary vein – commonly left upper pulmonary vein low flow PTA to Facilitate Impella Placement • Very uncommon to need PTA if pre placement angiogram is done • If stent is required – you must watch device pass stent under fluroscopy Probable ‘posterior’ plaque not appreciated on AP Aortogram PTA of distal Ao and Right and Left Iliac Arteries with 9 and 10 mm Balloons allowed placement of Impella Device via R CFA Optimal Device Placement: Impella •AL-1 and 0.035” J or straight wire to cross Aortic Valve exchange for Impella .018” wire back load device and insert through 13 F sheath RAO Projection LAO Projection Device Insertion Using Fluroscopic and Angiographic Guidance Optimal Puncture site Rim Catheter forceps Device Insertion Using Fluroscopic and Angiographic Guidance Insert movie name = wells_2 Puncture at Mid CFA under Angiographic Guidance Insert movie name = completion Completion Angiogram: No extravasation AND Normal distal flow Is Speed Important? • If critically ill patient IABP • Impella and/or Tandem Heart for several elective cases high risk PCI • Transition to ‘after hours’ and ‘emergent use’ once 2-3 cases have been done successfully • Always ask for help from 2nd operator and/or Senior Partner Device Malfunction Case 2 52 yo female with cardiogenic shock, s/p intubation, on multiple pressors, presumed myocarditis, on IABP and transitioned to emergent TH placement with initially excellent flows. Now with falling flow rates. CXR shows stable position of LA cannulae. HCT 28. Groins without hematoma. The most common reason for falling flow rates would be: A. Inadequate volume B. Hemolysis C. Recovery of left ventricular function Case 2 52 yo female with cardiogenic shock, s/p intubation, on multiple pressors, presumed myocarditis, s/p TH placement and initially with excellent flows. Now with falling flow rates. CXR shows stable position of LA cannulae. HCT 28. Groins without hematoma. The most common reason for falling flow rates would be: A. Inadequate volume B. Hemolysis C. Recovery of left ventricular function TH Placement following IABP IAPB in place. Left atrial angiogram via trans septal sheath to define left atrial anatomy. Normal sized left atrium. Optimize Hemodynamics • • • For critically ill patients, the use of a Swan Ganz Catheter can be helpful Optimal filling pressures can often be difficult to empirically determine Most patients require higher filling pressures than normal for example, RAP 10 and Wedge 20 mm Hg Case 3 70 yo male with cardiogenic shock, s/p placement of Impella Device via right femoral artery, HD#2, now with low flows, dark urine and falling Hematocrit. The next best step in management would be: A. Device removal B. Place IABP via contra-lateral femoral artery C. Send plasma free hemoglobin, LDH and haptoglobin Case 3 70 yo male with cardiogenic shock, s/p placement of Impella Device via right femoral artery, HD#2, now with low flows, dark urine and falling Hematocrit. The next best step in management would be: A. Device removal B. Place IABP via contra-lateral femoral artery C. Send plasma free hemoglobin, LDH and haptoglobin Impella Device Related Hemolysis ISAR-SHOCK J Am Coll Cardiol 2008;52:1584–8 Device Removal Device Removal: IABP Manual hemostasis (‘Fellow Device’) = proximal and distal control Device Removal: IABP with Manual Hemostasis Insert movie name = IMG_0737 Pre-Close Technique with 2 devices 10 o’clock 2 o’clock IABP Device Removal: Additional Options Remove 40 cc IABP via 8 F standard sheath place 8 F AngioSeal device using standard .035 J wire Bleeding Events: Impella/Tandem Heart Author/Year Device n Sjauw/2009 USpella/2012 Burkhoff/2006 Seyfarth/2008 Impella 2.5 Impella 2.5 TH TH 144 175 19 26 Thomas/2010 TH 37 Bleeding Requiring Transfusion 5.5 % 9.7 % 42 % PRBC 2.6±2.7 units 82 % • All patients should have and active Type and Cross with blood available • Working large bore peripheral or central line to give blood Problem: Cardiac Arrest • IABP – – – – Change to ‘internal mode’ Provides counter-pulsation at fixed rate of 80 bpm When stable, consider TVP and IABP triggered to TVP Correct acidosis, secondary issues Problem: Cardiac Arrest • Tandem Heart and Impella – – – – Continue support during CPR Consider ‘light’ CPR Confirm position of device when stable Consider echocardiogram (TH) when stable pericardial effusion Problem: IABP Balloon Rupture • Blood noted within balloon catheter by nursing or alarms from lack of sufficient inflation • Most commonly occurs after insertion and likely related to adjacent vessel calcium • Possibly related to insertion with damage to the balloon from adjacent calcium less likely • IABP must be removed – Is patient stable? Support with pressors – Replace IABP via CL FA or consider an alternative device Problem: Loss of Distal Pulses • Common for all devices – • Assess with physical examination – – – – • TH (15/17 F) > Impella (13 F) >> IABP (8 F) Color/temperature of leg/foot Evidence of embolic event Pulses by palpation and/or doppler Baseline pulse exam essential May require device removal Unique Solutions to Limb Ischemia • Antegrade SFA puncture with 4/5 F sheath • Antegrade sheath connected to the retrograde 15/17 F TH sheath with short tubing segment • ‘Auto’ perfusion of ischemic limb • Can only be done with Tandem Heart device Questions?