Download Transcripton/Translation Worksheet

Name
Hour
Date
For each of the following sequences, fill in either the DNA, the mRNA sequence, the rRNA anticodons, or
the amino acid sequences that have been left blank. If several sequences might work choose any one.
1. DNA
2.
TAC TGA TCG ACC CCC ATA ATG AAA ATC
mRNA
A U G
tRNA
UAC UGA UCG ACC CCC AUA AUG AAA AUC
AA
MET-THR-SER-TRP-GLY-TYR-TYR-PHE-STOP
DNA
T A C
C G C
T C C
G C C
G T C
G A C
A A T
A C C
A C T
mRNA
AUG
GCG
AGG
CGG
CAG
CUG
UUA
UGG
UGA
tRNA
UAC
CGC
UCC
GCC
GUC
GAC
AAU
ACC
ACU
AA
MET-ALA-ARG-ARG-GLU-LEU-LEU-TRP-STOP
3. DNA
A C U
A G C
U G G
G G G
U A U
U A C
U U U
U A G
TAC CAC CCC CGT ATG GCT GGG AAT ATC
mRNA
AUG GUG GGG GCA UAC CGA CCC UUA UAG
tRNA
U A C
AA
MET-VAL-GLY-ALA-TRY-ARG-PRO-LEU-STOP
C A C
C C C
C G U
A U G
G C U
G G G
A A U
A U C
GLY
( STOP)
Highlighted parts for 4 and 5 will be different for different students…
4. DNA
TAC GCA CCA AAA AAC TAC CAA GGT ATC
mRNA
AUG CGU GGU UUU UUC AUG GUO GGA UAG
tRNA
UAC GCA CCA AAA AAC UAC CAA GGU AUC
AA
MET
5. DNA
ARG
GLY
PHE
PHE
MET
T A C CTC ACA CTA CGA A T G TTG GGA ATT
mRNA
AUG GAG U G U
tRNA
UAC C U C ACA CUA CGA AUG U U G GGA A U U
AA
MET-GLY-CYS-ASP
G A U
GCU UAC AAC CCU UAA
ALA TRY-ASN PRO- STOP
VAL
6. What are the three differences between RNA and DNA?
DNA
RNA
Deoxyribose sugar-no oxygen
Ribose sugar-oxygen
Double stranded
Single stranded
Thymine
Uracil
7. Where is DNA found in the cell? nucleus Where is RNA found in the cell? Cytoplasm and nucleus
8. Name the three types of RNA and what they do.
Messenger RNA (mRNA) carries the message that will be translated to form a protein.
Ribosomal RNA (rRNA) forms part of ribosomes where proteins are made.
Transfer RNA (tRNA) brings amino acids from the cytoplasm to a ribosome.
9. Draw an mRNA strand that is complementary to the DNA strand AATTGC. Circle a nucleotide.
Etc…..make sure you have the phosphate and the ribose sugar…
10. What are the steps of transcription translation?
1.
For translation to begin, tRNA binds to a start codon and signals the ribosome to assemble. A
complementary tRNA molecule binds to the exposed codon, bringing its amino acid close to the
first amino acid.
2. The ribosome helps form a polypeptide bond between the amino acids and breaks the bond
between the first tRNA molecule and its amino acid.
3. The ribosome pulls the mRNA strand the length of one codon. The now empty tRNA molecule
returns to the cytoplasm. A complementary tRNA molecule binds to the next exposed codon.
Once the stop codon is reached, the ribosome releases the protein and disassembles.