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PharmaGuide INSTANT reference on the Medicines in GCC Countries SMARTPHONE VERSION GCC Edition GCC How to Use Smartphone Version (Including Overview of Contents) (Page 1 to 19) After you download the Application, spare a few minutes to read this “Manual” (Yellow Pages). It will tell you how to access data easily, quickly and smartly. You will know, ultimately, the features and benefits of the Smartphone Version. Start Here Brief Overview of Contents of PharmaGuide SMARTPHONE VERSION PharmaGuide SMARTPHONE VERSION contains comprehensive prescribing and trade information of all the medicines in the country for which the Application is available [e.g. GCC Edition contains information on all medicines available in GCC countries]. PharmaGuide SMARTPHONE VERSION is automatically updated monthly onto your Smartphone without any extra charges. All information including WHO/USFDA drug prescribing information updates, new products, price changes etc. are updated every month. This will help the medical and allied profession to remain always updated to information on all medicines available in their country. The following information in the following order will appear whenever you will search information for any product: Name of the Product Company Therapeutic Category: Appears in Black Colour below product name. 4 Drug Category: (e.g. sulphonylurea, biguanide….), if applicable, appears in Golden Colour after the therapeutic category. 5 Generic Name/Contents: Appears in Purple Colour after the therapeutic and drug category. In case of products having large number of ingredients (e.g. Centrum) complete formula of the product appears. 6 Dosage Form & Strength of the relevant product. 7 Pack Size & Retail Price: Will appear when Price Button is tapped. Re-tapping of this button will hide the pack & price information i.e. always tapping & retapping will show or hide the prices. Risk Factors 1 rice 2 3 (1) 8 Information provided under Risk Factors includes Contraindications, Precautions and Risks in Pregnancy & Lactation for the relevant product. 9 Dosage & Indications 10 For injectables, method of preparation and administration are made crystal clear. The diluent and their quantity are mentioned. 11 Interactions 12 Adverse Effects 13 Search for an Alternative product having SAME Content or SAME Drug Category or SAME Therapeutic Category. Administration Alternate Products (2) Explanation of the Buttons that has been used in the PharmaGuide SMARTPHONE VERSION: Customized Information Pharmaguide SMARTPHONE Version has the unique feature of mass customization. That means country specific data for all the six GCC countries are available. Information can be seen for any of the six GCC countries at the choice of the user with the click of a button. This feature increases the usability of the application and comfort level of the end user. PharmaGuide OPTIONS BAHRAIN KUWAIT PharmaGuide data is up-to-date. Select Country: U.A.E. OMAN QATAR SAUDI ARABIA Upgrade to complete date You are using Data on Cephalosporins only Help & Usage U.A.E. Check for data updates (Last Updated February 6, 2014) The user will have to select any one country of his choice. Once a country is selected, the data for all the six countries will be downloaded. Now the data for the selected country will appear. The selection will remain valid, until and unless the user selects another country from the option menu. To do so NO Internet connection is needed, this is an offline facility that the user can use as long as he desires. Enter new prepaid 14 - digit number Visit epharmaguide.com Exit Application You are registered with Email [[email protected]] Your Data Subscription Expires On This can be done (changed or re-changed) as many times the user desires. Tap here to upgrade to complete data if you have already downloaded FREE Application (from Play Store/App Store) with limited data on Cephalosporins only. Now the user have 14-digit number and want to have complete & updated data on all the medicines. How the user can see the data of any of the six GCC countries? Tap here to update data, the data is usually updated automatically but you may also update by tapping here. You must have internet connectivity to update data. The date on which it is updated appears below. Tap the options appear. the following screen will (3) Tap here to renew or extend subscription after you have new 14 - digit prepaid number. (4) Explanation of the Buttons that has been used in the PharmaGuide SMARTPHONE VERSION: Tap to go to Option Menu PharmaGuide GCC Edition U.A.E. Search P harmaGui de Type your search here... X Tap to find Search Price will appear when “PRICE Button” is tapped. Tapping & re-tapping will show or hide the prices. The currency name indicates the country of price & availability. If only currency name appears and no prices are mentioned, it means the product is available in that country but the prices are not available in the application. rice Tap “Yellow Button” or “Search Button” to Go to Search Screen Optional feature for refined specific search Colour Buttons. These buttons may or may not be used because all information can simply be seen by SCROLLING the Screen. Forward & Backward Shows the name of country selected and now you are seeing the data of that country only. This can be changed or re-changed as many times the user desires. (See previous page 3 & 4 to know how to change or re-change the country). Risk Factors Dosage & Indications Administration Currency (Abbreviation) AED BHD KWD OMR QAR SAR Interactions Adverse Effects Country UAE Bahrain Kuwait Oman Qatar Saudi Arabia Alternate Products rand While Scrolling tap “Black Button” to go to top of the screen Tap XX to clear the text (5) Tapping of this “BRAND Button”, will show you a list of Brands which are available for the Generic. This Button appears only when the user is searching information by Generic. (6) GCC Tap 'application icon' to start application and to go to search screen. Search Screen (Main Screen) This is the Main Screen and is to be used most frequently. This screen is mainly used to find information on any product. The user must be smart or well versed in using this screen. It is extremely important if the user wants to find and make use of the benefits of information provided in the PharmaGuide Smartphone Version. You can at any time tap X to clear the text in the box PharmaGuide GCC Edition U.A.E. Search P harmaGui de Type your search here... X Please type text in search box Brand Name The User can go to this Search screen at any moment by tapping this “Yellow / Search Button” How to Use this Search Screen: When this screen appears, Tap Search Box Area, Keyboard appears. Type text to find detail information on the next screen. As you type text, a list below will appear, you can also tap any one to go to next screen to see the detail information. IMPORTANT: You have to type ONLY any of these five options i.e. (1). Brand Name (2). Generic Name (3). Contents (4). Therapeutic Category. (5) Company Name. Other than these five types of information never type any other information for finding any information. (7) Generic Name (e.g. Cefoperazone) Contents (e.g. Cefoperazone and Sulbactam) Therapeutic Category (e.g. Cephalosporins) Company Name (8) As you type the text in the box of “Search Screen” the list below will show you in the following manner: PharmaGuide GCC Edition U.A.E. Search P harmaGui de When list appears Ace Magenta bullet before a line indicates a Brand Name Purple bullet before a line indicates Generic Name and/or Contents X ACE Inhibitors Ace-Bex Aceartin Black bullet before a line indicates a Therapeutic Category As you tap any item you will find detail information on the next screen. Aceclofenac Acef 1 2 3 4 5 6 7 8 9 10 q w e r t y u i o p ! @ # $ % & * ? / a s d f g h j k l _ - . ( ) - + z x c v b n m EN (9) ; , : . 12# ( 10 ) Hypoglycaemics excluding Insulins Sulphonylurea Glimepiride Tab 1 mg; 2 mg; 3 mg; 4 mg. Tab 1 mg 2x15’s: AED 25.00 Tab 2 mg 2x15’s: AED 44.50 Tab 3 mg 2x15’s: AED 62.50 Tab 4 mg 2x15’s: AED 75.00 rice On tapping a Brand Name, you will find information in the following order, colour and style. Scrolling of the screen will always allow you to see the continuing information. Amaryl Sanofi Aventis At any time, you may tap “Yellow Button” to go to Search Screen and search for any other product. hen appear w e PRICE will tapped. Th is n o t t u e Price B dicates th n i e m a n ty. currency availabili & e c ri p f s country o e the price d i h ll i w g Re-tappin RISK FACTORS: Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contra-ind: Insulin-dependant (type 1) diabetes mellitus; diabetic ketoacidosis; diabetic precoma or coma; hypersensitivity to glimepiride or other sulfonylureas or sulfonamides; serious renal or hepatic dysfunction; dialysis patients. Precautions: Regular monitoring of glucose levels in blood and urine. Milder or absent symptoms of hypoglycaemia, e.g. in patients with autonomic neuropathy or taking beta blockers, clonidine, reserpine, guanethidine or other sympatholytic drugs. Temporary change over to insulin in exceptional stress situations (e.g. trauma, surgery, infections with fever). DOSAGE (Alongwith Indications): Non-insulin-dependant (type 2) diabetes mellitus. Adults: Usual initial dosage 1 mg once daily; daily dosage may be increased at intervals of 1-2 weeks and carried out stepwise as follows: 1 mg, 2 mg, 3 mg, 4 mg, 6 mg and in exceptional cases 8 mg. Usual maintenance dose 1 mg to 4 mg daily. Children: Not recommended. ADMINISTRATION --INTERACTIONS Insulin, oral antidiabetics, ACE-inbibitors, allopurinol, anabolic steroids and male sex hormones, probenicid, quinolones, salicylates, sulfinpyrazone, sulfonamides, tetracyclines, tritoqualine, trofosfamide, barbiturates, corticosteroids, diazoxide, diuretics, epinephrine and other sympathomimetic agents, glucagon, laxatives, nicotinic acid (in high doses), oestrogens, phenothiazines, phenytion, rifampicin, thyroid hormones, H2-receptor antagonists, clonidine, reserpine; acute & chronic alcohol intake. ADVERSE EFFECTS Hypoglycaemia, signs of adrenergic counterregulation, hepatitis, liver failure, thromobocytopenia, heamolytic anaemia. ( 11 ) ( 12 ) Ceftriaxone Cephalosporins Inj 250 mg; 500 mg; 1 gm; 2 gm. rand On tapping a Generic Name (and/or Contents), you will find information in the following order, colour and style. Scrolling of the screen will always allow you to see the continuing information. AND” f this “BR st Tapping o w you a li o sh ll i w , le Button are availab h ic h w s of Brand eric. en G e th for RISK FACTORS: Pregnancy: No evidence of risk in humans. Lactation: Caution advised or effect undetermined. Contra-ind: Beta-Iactam hypersensitivity. Premature newborns having less than 41 weeks postmenstrual age; neonates over 41 weeks postmenstrual age with jaundice, hypoalbuminaemia or acidosis; concomitant treatment with IV calcium (including total parenteral nutrition containing calcium) in neonates over 41 weeks postmenstrual age - risk of precipitation in urine and lung. Do not use in hyperbilirubinemia neonates. Precautions: Severe renal and hepatic impairment. Do not use in pregnancy unless absolutely indicted. DOSAGE: (Alongwith Indications) Severe respiratory and genitourinary tract, bone and joint, abdominal infections, sepsis, meningitis. Adults: Usually 1 gm daily by deep IM., slow IV inj over at least 2-4 mins., or IV infusion. Severe infections, 2-4 gm as a single dose every 24 hours. Children: Usually 20-50 mg/kg once daily by IM inj., slow IV inj over at least 2-4 mins., or IV infusion. Severe infections, up to maximum 80 mg/kg daily (maximum 50 mg/kg in neonates). Doses over 50 mg/kg to be given by slow IV infusion over at least 30 minutes. Peri-op prophylaxis: Adults: 1 gm as single IM or slow IV dose. Colorectal surgery: Adults: 2 gm by IM, slow IV inj or infusion with anaerobic antibacterial. Lower Respiratory Infection: Adults: IM/IV: Usual: 1-2 gm once daily (or in equally BID doses). Max: 4 gm/day. Otitis Media: Children: 50 mg/kg IM single dose. Max: 1 gm/dose. Bone Infection: Adult: IM/IV: Usual:1-2 gm once daily (or in equally BID doses). Max: 4 gm/day. Meningitis: IV: Adults: 1-2 gm once daily (or in equally BID doses). Max: 4 gm/day. Children: Initial of 100 mg/kg (not to exceed 4 gm), then 100 mg/kg once daily or (in equally BID doses) for 7-14 days. Max: 4 gm/day. Septicaemia: IV: Adults: 1-2 gm once daily (or in equally BID doses). Max: 4 gm/day. Children: 50-75 mg/kg in divided doses every 12 hours. Max: 2 gm/day. Urinary Tract Infection: Adults: IM/IV: 1-2 gm once daily (or in equally BID doses). Max: 4 gm/day. Gonorrhoea: Single dose of 250 mg by IM inj. (Continued on Next Page.....) ( 13 ) ( 14 ) ADMINISTRATION: Ceftriaxone may be administered by IV intermittent infusion over 10-30 min; final concentration for IV administration should not exceed 40 mg/mL. The drug has also been administered by direct IV push over 2-4 min. Inject deep IM into large muscle mass. IM Injection: 250 mg/500 mg/1000 mg VIAL: To make concentration of 250 mg/mL add Water for Injection 0.9 mL in 250 mg vial; 1.8 mL in 500 mg vial; 3.6 mL in 1000 mg vial. IV: 250 mg/500 mg/1000 mg VIAL: To make concentration of 100 mg/mL add Water for Injection 2.4 mL in 250 mg vial; 4.8 mL in 500 mg vial; 9.6 mL in 1000 mg vial. Compatibility: Stable in D5W with KCL 10 mEq, D5W, D10W, NS, mannitol 5%, mannitol 10%, Sodium bicarbonate 5%, bacteriostatic water,SWFI. Stability: For IV infusion in NS or D5W, solution is stable for 3 days at room temperature or 10 days when refrigerated. INTERACTIONS: Oral contraceptives, calcium containing IV solns. ADVERSE EFFECTS: GI upset. skin reactions, blood dyscrasias. Rarely pseudomembranous colitis, raised liver enzymes, glucosuria, oliguria, haematuria, bronchospasm, phlebitis at inj. site, urinary and biliary precipitates, pancreatitis. PharmaGuide GCC Edition U.A.E. Ceftriaxone rand Ceftriaxon e Axone Pharma International Cebact Cadila You can tap any item on the List to see the detail information of the Brand. Scrolling will show further products in the list. You can also type brand name in the box to find products that contain the Ceftra Lupin same Generic. Cephalosporins Inj 250 mg; 500 mg; 1 gm; 2 gm. Type for Brand..... Advacef Neopharma X Megion Novartis ( 15 ) ( 16 ) An Outstanding benefit of PharmaGuide Smartphone Version: Find Alternate Products within SECONDS. Just Tap the Green Button Three different features for finding alternative products have been provided. You can use any of these three features by simply tapping the “GREEN BUTTON” 1) Search for an Alternative product having SAME Content. 2) Search for an Alternative product having SAME Drug Category. 3) Search for an Alternative product having SAME Therapeutic Category. 1) To Search for an Alternative of Amaryl having SAME Content. Amaryl Contains Glimepiride. Tap Glimepiride to find other products containing Glimepiride 2) To Search for an Alternative of Amaryl having SAME Drug Category. Amaryl Drug Category is Sulphonylurea. Tap Sulphonylurea to find other products containing Sulphonylurea PharmaGuide GCC Edition U.A.E. Am aryl Amaryl Sanofi Aventis Hypoglycaemics excluding Insulins Sulphonylurea Glimepiride Tab 1 mg; 2 mg; 3 mg; 4 mg. ALTERNATIVES Glimepriride Sulphonylurea Hypoglycaem... Type for Brand..... X Diapride Dar Al Dawa 3) To Search for an Alternative of Amaryl having SAME Therapeutic Category. Amaryl Therapeutic Category is Hypoglycaemics. Tap Hypoglycaemics to find other Hypoglycaemics Emipride Global Pharma G Pride Oman Pharma Tap any item on the list to see its detail information. ( 17 ) rice e.g. Searching for an Alternative of Amaryl: When you are seeing information of Amaryl, Tap the “GREEN BUTTON”, this screen will appear. Then tap any of the three “BOXES”. ( 18 ) Optional or Additional feature for Refined Specific Search For Refined Specific Search different Colour Buttons as shown below are provided. These buttons may or may not be used because all information, can simply be seen by SCROLLING the Screen. For example if Magenta Button is Tapped, Interactions of the product will appear. PharmaGuide GCC Edition U.A.E. Am aryl Amaryl Sanofi Aventis Hypoglycaemics excluding Insulins Sulphonylurea Glimepiride Tab 1 mg; 2 mg; 3 mg; 4 mg. INTERACTIONS Insulin, oral antidiabetics, ACE-inbibitors, allopurinol, anabolic steroids and male sex hormones, probenicid, quinolones, salicylates, sulfinpyrazone, sulfonamides, tetracyclines, tritoqualine, trofosfamide, barbiturates, corticosteroids, diazoxide, diuretics, epinephrine and other sympathomimetic agents, glucagon, laxatives, nicotinic acid (in high doses), oestrogens, phenothiazines, phenytion, rifampicin, thyroid hormones, H2receptor antagonists, clonidine, reserpine; acute & chronic alcohol intake. Risk Factors Dosage & Indications Administration Interactions Adverse Effects ( 19 )