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Dominique is General Manager at QFAB, a multi-institution collaboration whose
role is to provide advanced bioinformatics solutions to the biotechnology,
pharmaceutical, clinical and research communities. In this role, Dominique is
leading the development of QFAB’s platform for integrated and accessible
bioinformatics which combines collaborative tools, Omics data integration,
pathway and network analysis, High Performance Computing and Grid
technologies.
Prior to joining QFAB, Dominique was Head of Research at Bio-Layer, a biotech
company that became publicly listed in 2005. He has designed and developed a
high-throughput proteomics screening platform to improve applications in the
biotechnology, diagnostics and pharmaceutical industries. Integral to this
platform is a full hardware and software system for collection, management,
search and tracking of experimental data, including molecular structures,
biological and analytical data.
From 1997 to 2001, Dominique was team leader at Synt:em, a French
biopharmaceutical company focused on the discovery of drug candidates for
Central Nervous System diseases. He led the development of Synt:em
proprietary software, Diverser, specifically designed for molecular diversity
analysis and compound library design in the context of High-Throughput
Screening. He also developed methodologies based on unsupervised neural
networks for the analysis of large and complex chemical and biological datasets.
Prior joining Synt:em, Dominique was ARC Postdoctoral Research Fellow at the
Department of Biochemistry of the University of Sydney and then at the John
Curtin School of Medical Research in Canberra. During these two years, he
developed a computation method based on molecular dynamics simulations to
determine binding mode and free energy of binding of potential inhibitors. In
1993, he received his Ph.D. in computational chemistry from the University of
Bordeaux - France where he developed a computer program for the interactive
study and visualisation of molecular systems interactions.
Dominique has over 19 years experience in software development, information
management, data mining and data modelling applied to life science applications.
He is the author of more than 40 scientific publications and communications, and
is co-inventor of 3 patents. He is also member of the Australian Computer
Society.