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Lecture 2 - Cranial Nerve Examination Neurologic Examination A thorough neurologic exam can locate the focus of a brain lesion A comprehensive Cranial Nerve exam maps out much of the brainstem Requires simple portable equipment Seven Key Elements Mental Status Cranial Nerves Motor Sensory Coordination Deep Tendon Reflexes (DTRs) and Plantar Reflexes Gait Cranial Nerve Exam The cranial nerve exam should be carried out in an orderly fashion Do it the same way every time, this way you will not miss any steps The Olfactory Nerve – CN 1 Not routinely tested Test in any patient with a suspected frontal lobe disorder Ensure Patency of nasal passage Pt’s eyes closed, cover one nostril, identify familiar odors Mint, Coffee, Vanilla, Lavender Avoid Noxious Odors (alcohol). Defects Anosmia Lack of sense of smell Physical Obstruction Lecture 2 - Cranial Nerve Examination Genetic Causes Neurologic Defect (head trauma) Smoking Aging Use of cocaine The Optic Nerve – CN II Retinal signals travel through this nerve via the Optic Chiasm to the Visual Cortex Test visual acuity using a handheld card or Snellen chart Test each eye separately Directly visualize the nerve with an ophthalmoscope Use your right hand and right eye to evaluate the patient’s right, and your left hand and left eye to evaluate the patient’s left Pay attention to the optic discs. Visual field testing Have the patient cover one eye, hold your hands within easy visual distance from the patient’s face, one hand on each side in the peripheral vision and quickly hold up 1-2 fingers on each hand Ask the patient to count the total number of fingers held up A yellowish orange to creamy pink oval or round structure that lies medially. The normal monocular visual field extends approximately 100 degrees laterally, 60 degrees medially, 60 degrees superiorly and 75 degrees inferiorly. It is divided into nasal and temporal halves and superior and inferior altitudinal halves. A blind spot is located 15 degrees temporal to fixation and just below the horizontal meridian. Optic disc The point where the optic nerve enters the retina; not sensitive to light Simply carries blood vessels and nerves from the retina into the appropriate areas of the brain. Lecture 2 - Cranial Nerve Examination There are no receptors here for vision which is why we have a blind spot. Damage anywhere in the visual pathway from the eye to the visual cortex can cause specific deficits in the visual fields of one or both eyes. Importantly, some visual information from each eye crosses to the opposite side at the optic chiasm. Lesions in front of the optic chiasm (optic nerve lesion) cause visual deficits in one eye – 1&2 on schematic. Lesions at the optic chiasm – involve only fibers that are crossing over to the opposite side & these fibers originate in the nasal half of each retina causing blindness in the temporal half of each field (bitemporal hemianopsia) – 3 on schematic. Lesions behind the optic chiasm (optic tract, thalamus, white matter, and visual cortex) cause visual field deficits that are similar for both eyes (homonymous hemianopsia) – 4&5 on schematic. Clinical correlation When transected, ipsilateral blindness (amaurosis) and loss of direct pupillary light reflex results When subjected to increased ICP (tumor), papilledema is the result Regeneration of the optic nerve does not occur A “choked” optic disk When constricted, optic atrophy results (axonal degeneration) Optic Nerve – CN II and Oculomotor Nerve – CN III Pupillary Testing The optic nerve (II) is responsible for the afferent limb of the pupillary reflex - it senses the incoming light. The oculomotor nerve (III) is responsible for the efferent limb of the pupillary reflex - it drives the muscles that constrict the pupil Direct reaction (pupillary constriction in the same eye) Consensual reaction (pupillary constriction in the opposite eye) The swinging flashlight tests direct and consensual responses Lecture 2 - Cranial Nerve Examination Accommodation --the pupils constrict while fixating on an object being moved from far away to near the eye (Oculomotor nerve) Pupils will constrict as the focal point shortens. Ask the patient to focus on your finger and move it towards the patient in the midline and watch for pupillary constriction Abnormal Pupillary Findings Argyll-Robertson Pupil Seen in Syphilis, and rarely diabetes, the neuropathy results in the loss of constriction to light but accommodation response is preserved Marcus-Gunn Pupil (Afferent Pupillary Defect) Total absence of response to light or accommodation Consensual response preserved For example, both pupils always dilate and constrict the same, so that they appear equal in size to each other. They both constrict when the light is in the good eye, and they both dilate when the light is in the bad eye Oculomotor Nerve – CN III CN III projects postganglionic parasympathetic fibers to the sphincter muscle of the iris (miosis = constriction) and to the ciliary muscle (accommodation) Levator Palpebrae Superioris CN III Palsy droopy eyelid Lecture 2 - Cranial Nerve Examination Raises upper eyelid Medial Rectus Medial gaze Primary = adduction Superior Rectus Upward and inward gaze Primary = elevation Secondary = intorsion Tertiary = adduction Inferior Rectus Downward gaze Primary = depression Secondary = extorsion Tertiary = adduction Inferior Oblique Upward and out gaze Primary = extorsion Secondary = elevation Tertiary = abduction CN III – Superior Rectus, Inferior Rectus, Inferior Oblique, Medial Rectus CN IV – Superior Oblique CN VI – Lateral Rectus Trochlear Nerve – CN IV Superior Oblique Lecture 2 - Cranial Nerve Examination Downward and inward gaze Primary = intorsion Secondary = depression Tertiary = abduction Via the Trochlea (Pulley) To compensate for IV nerve palsy –the pt will tilt their head toward the unaffected side Abducens Nerve – CN VI Lateral Rectus Lateral Gaze Primary = abduction Extraocular Muscle Testing Check extraocular movements by having the patient look in all directions without moving their head and ask them if they experience any double vision Look for deviation, palsies and nystagmus Clinical Correlation Below: Oculomotor Palsy (III) o Ptosis “Down and Out”, due to unopposed lateral rectus and superior oblique Above: Trochlear Palsy (IV) o Utilizing head tilt Superior lateral gaze Right: Abducens Palsy (VI) o Esotropia Loss of lateral gaze Trigeminal Nerve – CN V Sensory Function Sensation to distributions as listed Lecture 2 - Cranial Nerve Examination Nerves do not cross the midline test both sides Test by stroking three divisions with swab, pin-prick, temperature Motor Function (V3) Muscles of Mastication Ask patient to clench teeth and feel masseters thicken If there is pathology in CN V-3: upon mouth opening, jaw will deviate toward the side of lesion Corneal Reflex Cornea sensation provided by V1 Light stroke of cornea with swab causes BILATERAL blinking Motor response = CN VII Paralysis of tensor tympani Loss of reflex is an indication of pathology at CN V-1 Results in hypoacusis, partial deafness to low-pitched sounds Trigeminal Neuralgia (CN V-3) Tic Douloureux Lecture 2 - Cranial Nerve Examination Painful neuropathy of one segment of CN V Facial Nerve – CN VII Sensory (Taste) Test discrimination of salt, sweet, sour on anterior portion of tongue rarely tested Motor Raising Brow test upper division Squeezing eyelids test upper division Puffing Cheeks test lower division Smiling test lower division Clinical Correlation o Supranuclear Lesion Involves corticobulbar pathways Produces contralateral weakness of the lower face, with normal function of upper face Bilateral innervations of upper face by corticobulbar fibers Unilateral innervation of lower face from contralateral cortical centers “Forehead Sparing” Stroke o Infranuclear Lesion Total involvement of the ipsilateral facial muscles, with no area being spared Results from lesions of the nerve as it exits from the skull or from involvement of the facial nucleus in the pons Bell’s Palsy Auditory Nerve – CN VIII Cochlear Testing Identify gross hearing deficits Rinne Test (Conductive) Bone vs Air Lecture 2 - Cranial Nerve Examination Hold Fork on mastoid until no longer audible then place in front of ear conductive loss if BC>AC Weber Test (Sensorineural and Conductive) Fork in middle of head Sound lateralizes towards side with conductive hearing loss Sound lateralizes away from side with sensorineural loss Can perform formal auditory testing for further delineation of pathology Vestibular Testing Part of the extraocular movement testing (nystagmus) Gait examination (ataxia) Station evaluation (may fall on Romberg) CN VIII lesions would result in hearing loss, tinnitus, vertigo/dizziness, or nystagmus Glossopharyngeal Nerve - CN IX Sensory Function Taste in Posterior 1/3 of tongue Rarely tested Sensation to posterior pharynx and tonsils. Motor Function (With Vagus Nerve CN X) Innervates the muscles of the pharynx and palate Necessary for proper initial phase of swallowing Vagus Nerve – CN X For the cranial nerve X exam we focus mainly on its motor function of the pharynx and larynx (sensory component comes from CN IX) Testing of CN IX and X Motor Function of the pharynx/larynx is shared by both cranial nerves IX and X Lecture 2 - Cranial Nerve Examination Open wide and say “ahhh” Look for symmetric elevation of the Uvula Bilateral loss = no elevation Unilateral Loss = Elevation toward the strong side See Faucilar Pillars Converge (each side of posterior pharynx moves medially, like a curtain) Gag Reflex (“In by IX and out by X”) Laryngeal Testing – Should see elevation of larynx with swallow Hoarseness Vagus nerve (via recurrent laryngeal) innervates vocal cords In a CN X lesion the palate will droop and the uvula will deviate away from the side of the lesion Accessory Nerve CN – XI Innervates Trapezius and Sternocleidomastoid Muscles Testing Trapezius Shoulder Shrug Sternocleidomastoid Head Rotation and Resistance to lateral jaw pressure Weakness or inability to do these tests would indicate a CN XI lesion Hypoglossal Nerve – CN XII Provides Motor Function to tongue Look for fasiculations With tongue resting in floor of mouth If present, indicates hypoglossal LMN lesion Have patient stick his/her tongue out at you Lecture 2 - Cranial Nerve Examination Deviates toward the same side of the lesion if one is present Say “lalalalala”