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Structures of the Cardiovascular System Major Arteries and Veins Common Core and Standards Common Core Standards for Literacy in Social Studies, Science, and Technical Subjects; # 2- Determine the central ideas or conclusions of a text; summarize complex concepts, processes or information presented in a text by paraphrasing them in simpler but still accurate terms. #9 – Synthesize information from a range of sources into a coherent understanding of a process, phenomenon or concept, resolving conflicting information when possible. Living Environment Standards - #4 Key Idea; Living things are both similar to and different from each other and non-living things Key Idea; Organisms maintain a dynamic equilibrium that sustains life Aim: What are the major arteries and veins in the human body? Do Now.. Turn and talk with your partner, and discuss what the difference is between Arteries and Veins Cardiovascular System The heart, blood and blood vessels compose the Cardiovascular system. This system transports fluids throughout the body. Cardiovascular System The cardiovascular system is a closed system in which the heart pumps blood into the arteries connected via capillaries to veins. Veins then carry the blood back to the heart. Arteries The main arteries are; Pulmonary Arteries Which carries blood to the lungs Aorta Which carries blood to the rest of the body Veins Pulmonary Veins Which return blood from the lungs to the heart Superior Vena Cava Which carries blood from the upper parts of the body Inferior Vena Cava Which carries blood from the lower parts of the body Bacterial Cardiovascular and Systemic Diseases Septicemia, Bacteremia and Toxemia Bacterial effects on the Cardiovascular System Septicemia Refers to the presence of microbial infection of the blood that causes illness. Bacteremia Is bacterial Septicemia Toxemia When bacteria remains fixed at the site of the infection and releases toxins into the blood. Aim: What is Septicemia and what are some ways to induce it? Do Now: A patient at a local hospital has to have their appendix removed, a routine and very safe procedure. The patient is accompanied by their spouse as the doctor tells them about this procedure. The patient is not worried at all and is currently enjoying a beautiful steak sandwich for dinner. The patient feels as wonderful as they can be. The next day the patient goes under as the anesthesiologist does their job. The procedure ends up going horribly wrong and the wife has been arrested for manslaughter. Why? What is Septicemia? Septicemia is a serious and even life-threatening infection of the blood. Usually it is caused by bacterial infection, but fungi and other organisms also cause this widespread infection of the bloodstream. “Bacteremia” is another term that denotes the presence of bacteria in the bloodstream. Symptoms are related to the chemicals produced during the body’s immune response to the massive infection. Lymphangitis Septicemia can lead to an infection of the lymphatic system in which inflamed lymphatic vessels become visible as red streaks under the skin. Causes of Septicemia Antibiotic resistant strains or bacteria Close contact with someone who has septicemia Complicated labor and delivery Compromised immune system due to AIDS, cancer chemotherapy or other reasons Indwelling catheters ( such as intravenous lines, urinary catheters, etc.) Localized infections (of a specific organ, tissue or region) Very young age (infants) or advanced age (the elderly) Signs and Symptoms of Septicemia With septicemia, a person’s condition can decline very rapidly. The initial symptoms include accelerated pulse, rapid breathing, chills, and high fevers that come on suddenly. These may lead to septic shock which is a sudden decrease in blood pressure, and confusion or other mental changes. Red spots may occur on the skin as a result of clotting problems in the blood. Aim: What are the treatments and preventions of Septicemia? Do Now: What are some causes of septicemia? Bacterial Septicemia - Petechiae Bacterial Septicemia can trigger Petechiae Which are skin legions that are small and relatively diffuse, or may coalesce to form large black sores which contain dead cells. Toxemia - TSLS Toxemia will manifest differently depending on what toxins are involved. A severe form of Toxemia with Septic shock is TSLS (Streptococcal toxic-shock-like syndrome), in which the patients blood pressure drops very low and they may suffer from dizziness, confusion, difficulty breathing and their liver and kidneys may fail. Diagnosis Physicians diagnose Septicemia based upon signs and symptoms, and are able to culture bacteria from the blood of fewer than half of patients with characteristics signs and symptoms of sepsis; The majority of patients therefore have ‘occult septicemia’ a term referring to the fact that the exact bacterial cause is hidden. Treatment Treatment of septicemia requires hospitalization, typically in the intensive care unit (ICU), where you will be given fluids and medications intravenously. You will receive antibiotics to fight the infection, as well as supplemental oxygen, plasma or other blood products to help with blood-clotting problems and other abnormalities. Respiratory support, sometimes in the form of a ventilator (breathing machine) or hemodialysis, may be required. Septicemia is a very serious illness that can be fatal. It is imperative that you seek medical attention immediately and that you follow your healthcare provider’s treatment plan exactly. Prevention Prevention of Septicemia depends on the prompt treatment of the infection. If treatment is delayed, bacteria multiply and the use of some antimicrobial drugs can worsen a patient’s condition. Early diagnosis and treatment are vital. Summary/Formative Assessment Fill in the handout.