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The Cardiovascular System Physiology of Circulation Compare and Contrast – Arteries & Veins Arteries - Characteristics • Thicker tunica media – smooth muscle layer • Smaller lumen • Elastic – stretch and recoil as blood is pumped through • High pressure • Carry blood away from heart Veins - Characteristics • Thin tunica media (smooth muscle layer) • Larger lumen • Rely on other structures to help return blood to heart – Valves – Skeletal muscle – Pressure changes in thoracic cavity Arterial Pulse • Pulse: the alternating expansion and recoil of artery as the left ventricle contracts • Usually equals pulse rate – Normal pulse rate: 7076 bpm • Pressure points: pulse points compressed to stop blood flow Blood Pressure • Pressure blood exerts against the inner walls of the blood vessels • Blood flows from aorta arteries arterioles capillaries venules veins vena cava – Pressure is strongest at the aorta, and zero at the vena cava You Decide: • Which was cut in the man – an artery or vein? How do you know? • http://www.youtube.com/watch?v=hsM0Cwq GrBs Measuring Blood Pressure • Systolic pressure: pressure in arteries at the peak of ventricular contraction • Diastolic pressure: pressure when ventricles relax • normal BP: 120 (systolic)/80 (diastolic) Factors affecting blood pressure • Peripheral resistance – Friction encountered as blood flows through vessels – Age, weight, time of day, exercise, body position, emotional state, drugs • Neural factors – Sympathetic system causes vasoconstriction of vessels which increases blood pressure • Renal factors (kidneys) – Alter blood volume – As BP increases above normal, kidneys excrete more water into urine Factors Continued • Temperature – Cold causes vasoconstriction, heat is a vasodilator • Chemicals – Nicotine causes vasoconstriction (increases bp), alcohol causes vasodilation (decreases bp) • Diet – Low salt, saturated fats and cholesterol help prevent hypertension (high bp)