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Top Pap smear Questions
1-When should Pap screening begin?
Age 21 y/o,3yrs after first intercourse
2-What are screening methods&intervals(for Pap &HPV)?
Cytology:
1-Conventional(20%FN)
2-Liquid-based :
Surepath
Thinprep
Focal point
-HPV co-test(cytology+HPV test)
-primary hrHPV testing(16+18+pool results of 12 other
hrHPV)
-Every 3yrs(conventional or liquid-based)
3-When can women C/C Pap smear?
Aged>65 with adequate negative prior screening & no history
of CIN2 or higher within the last 20 yrs
4-What are RF for HPV INFXN?
A-Multiple sex partners
B-High-risk partners
C-Cigarette smoking
D- Immunodificiency
E-HX of STD
F- Early age at first intercourse
5- What are the three HPV vaccines?
A- Gardasil (quadravalent )for protection against HPV
16,18,6,11
B- Cervarix (bivalent) for protection against HPV 16,18
C- Gardasil 9(9-valent)for protection against HPV
16,18,6,11,31,33,45,52,58
6- What are the 6 components of the Pap smear ?
A- Description (Conventional or liquid – based )
B- Description of Adequacy ( Satisfactory )
C- General Category (negative or positive for epithelial cell
Abnormality )
D- Interpretation / Result
E- Description of ancillary testing (hr HPV Test )
F- Educational notes & Suggestion (optional)
7- What are some non-neoplastic Pap smear findings??
Yes. A-INFXN: Trichomonas , fungi (Candida), BV, HSV2,nonspecific
B- Reactive: Inflammation , radiation , IUD
C- Atrophic change
8- Do women who have been vaccinated against HPV still need to be
screened for cervical cancer?
Yes.
Current HPV vaccines do not protect against all HPV types that
cause cervical cancer
9- Can HPV infections be prevented?
A- Not sexually active
B- Vaccine
C- Condom
10- What are the aims of Pap smear?
A-Detection of precancerous cervical lesions
B- Detection of inflammatory & infectious cervical lesions
( especially HPV)
C-Detection of cervical cancer
D- Hormonal evaluation
E- Follow up of cervical cancer
11- When is the best Time to get a Pap smear in a month?
A- Mid-cycle or two weeks after the last LMP
B- 12 weeks or
3 months postpartum
12-How to prepare for a Pap Test?
Avoid intercourse,Douching & vaginal inserts for 24 to 48h
13-What is the relationship between HPV & cervical cancer ?
A- It is more important than association between cigarette
smoking & lung cancer
B- Extremely common ( most common viral infection of the
reproductive tract)
C- Over 100 types of HPV , At least 15 HR type
D- HPV16 , 18 cause 70% of cervical cancer & precancerous
cervical lesions
E- Skin – to – skin genital contact is a well-recognized mode of
Transmission
14-Does having HPV or abnormal cervical cells affect chances of getting
pregnant or have healthy babies?
A- No
B- But if one needs treatment , it could affect fertility or carrying a
baby to term
15- Is there any test for men to find out if they have HPV?
A – No
B- Genital warts
16- Do one need to check LR HPV Test ?
A- No disease progression
B- No change Treatment
17- Do need to continue Pap test in patients with history of endometrial
caner?
- No
18- Who should not have the Pap Test?
A- <21 Y/O
B- No sexual activity
C- Had total hysterectomy for non-cancer lesions
D- Aged>65 years with adequate screening history
E- Dialysis Patients with limited life expectancies without sign &
symptom (ASN)
19- What are the most important references for Pap Test?
A- American Society for Clinical Pathology (ASCP)
B- American Cancer Society (ACS)
C- American Society for Colposcopy & Cervical Pathology (ASCCP)
D- U.S. Preventive Services Task Force (USPSTF)
E- American College of Obstetricians &Gynecologists (ACOG)
F- National Cancer Institute (NIH)
G- Society of Gynecologic oncology (SGO)