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Stomach Objectives At the end of the lesson, the student will be able to… 1. Name the parts of the stomach, including the layers, regions, and sphincters 2. Identify the functions of the different cells in the stomach and what they secrete 3. Identify how the stomach digests food and contributes to the overall digestive system 4. Name the functions of the sphincters of the stomach 5. Define the greater and lesser omentum and what role they play in aiding the stomach 6. Trace the path of food from the stomach to the small intestine Stomach • C-shaped, on the left side • Hidden by liver and diaphragm • Multiple regions o Cardiac o Fundus o Body o Pyloric antrum o Pylorus • 3 muscular layers to help mix and breakdown food • Longitudinal layer, circular layer, oblique layer Stomach Stomach • Expands and collapses based on food content • When collapsed, the mucosa forms folds called, rugae What holds it in place?? • Lesser omentum- o Connects liver to “inside” curve of stomach • Greater omentum- o Connects large curve of stomach to the intestines Both are… • Extensions of visceral peritoneum • Riddled with fat (insulate & protect internal organs) o many lymph nodes Stomach • Food enters the stomach from the esophagus through the cardiac sphincter • Chemical breakdown of proteins starts in the stomach • The mucosa is composed entirely of mucous cells that produce a protective layer of bicarbonate-rich alkaline mucus • Smooth lining is dotted with gastric pits that go to gastric glands Secretions in the Stomach • Gastric glands- secrete gastric juice • Chief cells- produce protein digestion enzymes- pepsinogen (before activated, pepsin when activated) • Parietal cells- produce HCl and intrinsic factor • Mucous neck cells- thin acidic mucous • Enteroendocrine cells- produce hormones such as gastrin • Why do we need all of these???? Stomach to Small Intestines • Most digestion occurs in pyloric region of stomach • Chyme- processed food • Chyme enters the small intestine through the pyloric sphincter • Chyme enters the stomach slowly…one squirt at a time until the stomach is empty Stomach Video • http://www.youtube.com/watch?v=URHBBE3RKEs Stomach Illnesses • Heartburn- backflow of chyme into the esophagus • Acid Reflux- chronic heartburn • Gastric ulcers- stomach lining is eroded by gastric juices faster than it can regenerate • Caused by bacteria Helicobactor pylori- acid tolerant bacteria • How??? Peptic Ulcers • Bacteria destroys the mucous lining • NOT caused by stress & spicy foods • Symptoms: o o o o Pain navel-chest Blood in vomit or stool Temp. relief w/ antacids Pain comes & goes Review Activity • Think-pair-share • Get into pairs • Trace the path that food takes from the mouth to the small intestine Objectives 1. Trace the path of food from the stomach to the small intestine 2. Identify the parts of the small intestine- duodenum, jejunum, and ileum 3. Identify the functions of the pancreatic duct and bile ducts in the small intestine and how they contribute to digestion 4. Discuss the function of the microvilli, villi, circular folds, and lacteal in digestion 5. Identify the parts of the large intestine, including the cecum, appendix, colon (ascending, transverse, descending, sigmoid, anus), rectum, sphincters, and anal canal 6. Identify the pancreas, liver, and gallbladder, and their function in digestion 7. Understand defecation reflex Small Intestine • Longest part of the alimentary canal • Named the “small” intestine because of its small diameter- 2.5 cm across • Major organ for chemical digestion • Goes from the pyloric sphincter to the large intestine Let’s Talk about pizza. • What? • Where? • How? • What happens next? Small Intestine and Accessory Organs • Duodenum- first part of the small intestine~5% • Jejunum- 40% • Ileum- 60% (both absorb nutrients • Chyme is mixed with enzymes and transformed by: • Liver- makes bile • Pancreas- glandsecretes “juice” from a duct • Gallbladder- stores bile The Bile Path • Bile is produced by the liver • Stored in the gallbladder • Contains salts that emulsify fats • Prevents fat droplets from re-forming large globules • Causes fats to be more accessible to lipase Absorption of Nutrients • Villi- fingerlike projections (each has microvilli on it) • Microvilli- tiny projections of mucosa cells; make the brush border • Lacteal- lymphatic vessel in each villus • Increase surface area, increase rate of absorption Large Intestine • Main part is the colon • Functions: • • • • • Drys out indigestible food: ex: cellulose Elminates waste as feces Produce alkaline mucus Absorb nutrients produced by bacteria in colon No villi Large Intestine Troubles with the Large Intestine • Diarrhea- lining of the colon becomes irritated by a viral or bacterial infection, resulting in less absorption of water • Constipation- feces is moved along the colon too slowly, too much water is absorbed and feces becomes hard. • Celiac’s disease- protein, gluten, triggers an immune response that leads to swelling and lack of nutrient absorption • Crohn’s disease- inappropriate immune response that leads to chronic inflammation Rectum • Stores feces until they can be eliminated • Contractions of the colon and rectum create urge to defecate • Anus is controlled by 2 sphincters- one voluntary, one involuntary • Voluntary sphincter relaxes, feces is expelled through the anus Digestive Enzyme Video • http://www.youtube.com/watch?v=vTQybDgweiE Review • Trace the path of food from the mouth to the anus. Use the 4 functions of the digestive system in your answer, specifying where each happen. • • • • Ingestion Digestion Absorption Elimination