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SESAME STREET GENETICS ACTIVITY Introduction: It is an exciting time for geneticists as they have just discovered the genome for Sesamus muppetis (sesame street characters). They have determined that Sesame Street characters have six chromosomes. On these chromosomes they have found specific locations of the following genes: eye shape, nose color, lip color, body color, hair type, blood type and certain genetic disorders. Due to your expertise in the genetics area they have hired you as their apprentice to finish the job. Your Job as a Genetic Apprentice You were hired as an apprentice to the geneticists. Your task: 1) Research traits of specific Sesame Street characters and identify their genotypes and matching phenotypes. 2) “Mate” two Sesame Street characters and determine the probability of their monster children’s traits using punnett squares. 3) Create two new Sesame Street children using your punnett square probability and fill out a monster profile for each. 4) Draw your Sesame Street family portrait and present to class, including a list of family members, genetic make-up and monster profile of children. CHECKLIST Your performance will be assessed based on completion of the job you were hired to do. To mark your progress, use the following checklist. Date Completed: ____________ Observation of Genetics Traits of each Character (10 pts.) ____________ Monster Mates Genetic Profile (10 pts.) ____________ Sesame Street Punnett Squares (10 pts.) ____________ Creating Monster Offspring (10 pts.) ____________ Sesame Street Family Portrait and Presentation (10 pts.) ____________Third Generation Monsters (10 pts) All Work Due on Presentation Date: __________ OBSERVATION OF GENETIC CHARACTERISTICS Instructions: Using table 1.1, fill in the genotypes and phenotypes tables below. GENOTYPES TABLE Eye Shape Nose Color Body Color Hair Type (Not Fur) Fingers Grover ee PP RO XhY Ff Elmo EE PY RR XhY FF Zoe Ee PP OO XHXh Ff Telly Ee PY BO XHY FF Green Honker Ee PY RB XHY Ff Rosita Ee PY RB XHXh Ff C. Monster Ee RO XhY Ff Abby ee BB XHXh Ff Hair Type (Not Fur) Fingers PP PHENOTYPES TABLE Eye Shape Nose Color Body Color Grover Endo Pink Blue Bald Y Elmo Exo Orange Red Bald Y Zoe Exo Pink Orange Hair Y Telly Exo Orange Magenta Hair Y Honker Exo Orange Green Hair Y Rosita Exo Orange Teal Hair Y C. Monster Exo No Nose Blue Bald Y Abby Endo Pink Pink Hair y GENETICS OF SESAME STREET CHARACTERS (Table 1.1) Characteristic Eye Shape Phenotype Exo (pops out) Endo(flat) Genotype EE, Ee ee Type of Inheritance Dominant/recessive Nose Color Pink Orange Yellow No Nose PP PY YY Incomplete dominance Body Color Red Teal Green Blue Magenta Orange Pink RR RB RB RO BO OO BB Multiple alleles; R,B, & O Incomplete dominance Hair Type Hair XHXH XHXh XHY XhY XhXh X-Linked (Sex Linked) FF, Ff ff Dominant/Recessive Bald Fingers Fingers No Fingers Muppet Mates Genetic Profile Elmo (Monster’s Name) Characteristic Eye shape Genotype EE Type of Inheritance Mendelian/Simple Inheritance PY Incomplete Dominance RR Incomplete Dominance Hair Type Red Bald XhY X-Linked Fingers Yes FF Mendelian/Simple Inheritance Characteristic Eye shape Phenotype Exo Genotype Ee Type of Inheritance Mendelian/Simple Inheritance Nose Color Pink PP Incomplete Dominance Body Color Orange OO Incomplete Dominance Hair Type Hair XHXh X-Linked Fingers Yes Ff Mendelian/Simple Inheritance Nose Color Phenotype Exo Orange Body Color Zoe (Monster’s Name) SESAME STREET PUNNETT SQUARES Please fill out the following Punnett Squares in order to determine the possible traits of the Muppet Babies you will create. Then, using the space below each Punnett Square, tell the probability for each phenotype (dominant and recessive). First, write the probability as a ratio, i.e., 1:4, next as a percent, i.e., 25%. Gender X X XX XX X Y Hair Type: XhY x XHXh Xh XY XH XHXh XHY Xh XhXh XhXy XY (female) = 2:4 = 1:2= 50% XY (male) = 2:4 = 1:2 = 50% Genotype Percentages: All 25% Phenotype Percentages: 50% Hair 50% Bald Eye Shape: EE x Ee E E e R EE EE Ee Ee O Genotype Percentages: EE 50% Ee 50% Phenotype Percentages: 100% Exo P P P Body Color: RR x OO E Nose: PY x PP PP PP Y O R RO RO RO RO Genotype Percentages: RO 100% Phenotype Percentages: Blue 100% Fingers: FF x Ff Y PY PY Genotype Percentages: PP 50% PY 50% Phenotype Percentages: Pink 50% Orange 50% F f F F FF FF Ff Ff Genotype Percentages: FF 50% Ff 50% Phenotype Percentages: Fingers 100% CREATING MONSTER OFFSPRING Now that you have crossed your monsters, create two muppet children. One muppet child should have the most likely characteristics (highest probabilities) from your punnett squares. You can be creative with your second child, but you need to make sure that it has the possibility of having traits based on your punnett square results. Name your monster children. Draw a family portrait that includes all the inherited characteristics. Name of Monster Child #1 Zelmo Characteristic Phenotype Genotype Type of Inheritance Sex Eye shape Nose Color Body Color Hair Type Fingers Male Exo Pink Blue Hair Yes XY EE PP RO XHY FF Mendelian Mendelian Incomplete Dominance Incomplete Dominance X- linked Mendelian Probability of Trait (pheno) 50% 100% 50% 100% 50% 100% Name of Monster Child #2 Moe Characteristic Phenotype Genotype Type of Inheritance Sex Eye shape Nose Color Body Color Hair Type Fingers Female Exo orange Blue Bald Yes XX Ee PY RO Mendelian Mendelian Incomplete Dominance Incomplete Dominance X- linked Mendelian XhXh Ff Probability of Trait (pheno) 50% 100% 50% 100% 50% 100% Family Portrait: Draw children here:
